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01.12.2014 | Meeting abstract | Sonderheft 1/2014 Open Access

The Journal of Headache and Pain 1/2014

EHMTI-0245. Some clinical characteristics and prophylactic treatment in patients with moh in an out-patient clinical sample

The Journal of Headache and Pain > Sonderheft 1/2014
M Jovanovic, N Buder


Medication Overuse Headache (MOH) is a well-known condition and diagnostic entity, recognized as a relevant medical and socio-economic problem everywhere. Whether initial primary headache type, its frequency, co-morbid conditions or else, it is not truly clear. The therapeutic management of MOH is often difficult and still not properly and step-by-step guided.


We wanted to point out and compare some clinical features of patients with MOH, migraine and tension type headache, as well as their response to prophylactic treatment.


We considered a group of 100 out-patients, adults and both sexes, according to headache diagnosis (ICHD-III) - migraine (M), tension type headache (TTH), co-existence of M and TTH (M+TTH) and MOH, previous headache in MOH group and attack frequency. Therapeutic response to applied various prophylactic single or combined medications (from the Guideline of EFNS) was estimated as an initial response and/or in a followed-up period of 6 months.


There were 74 females and 26 males, 38 with M, 23 TTH, 20 M+TTH and 19 with MOH (19%) - 7 previously had M, 5 TTH and 7 M+TTH. 40 patients had less and 60 more than 15 headache days per month. Of 94 patients treated by prophylactic medication 74 (78,7%) responded and 20 (21,3%) did not - 3 had M, 8 TTH, 3 M+TTH and 6 MOH.


Focused MOH group and specially those poor responders to prophylactic treatment did not show any significant differences compared to other, mostly chronic, primary headache. Although difficult to manage, MOH is a treatable condition.
No conflict of interest.
Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License ( https://​creativecommons.​org/​licenses/​by/​4.​0), which permits use, duplication, adaptation, distribution, and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
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