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Zeitschrift

EJNMMI Research

EJNMMI Research 1/2016

Ausgabe 1/2016

Inhaltsverzeichnis ( 91 Artikel )

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Preclinical imaging of the co-stimulatory molecules CD80 and CD86 with indium-111-labeled belatacept in atherosclerosis

Romana Meletta, Adrienne Müller Herde, Patrick Dennler, Eliane Fischer, Roger Schibli, Stefanie D. Krämer

01.12.2016 | Short communication | Ausgabe 1/2016 Open Access

Impact of fasting on 18F-fluorocholine gastrointestinal uptake and detection of lymph node metastases in patients with prostate cancer

Maurits Wondergem, Friso M. van der Zant, Remco J. J. Knol, Jan Pruim, Igle J. de Jong

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Imaging heterogeneity of peptide delivery and binding in solid tumors using SPECT imaging and MRI

J. C. Haeck, K. Bol, C. M. A. de Ridder, L. Brunel, J. A. Fehrentz, J. Martinez, W. M. van Weerden, M. R. Bernsen, M. de Jong, J. F. Veenland

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Targeted scVEGF/177Lu radiopharmaceutical inhibits growth of metastases and can be effectively combined with chemotherapy

Mary Rusckowski, Yuzhen Wang, Francis G. Blankenberg, Zoia Levashova, Marina V. Backer, Joseph M. Backer

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

177Lu-labelled macrocyclic bisphosphonates for targeting bone metastasis in cancer treatment

Ralf Bergmann, Marian Meckel, Vojtěch Kubíček, Jens Pietzsch, Jörg Steinbach, Petr Hermann, Frank Rösch

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Influence of tumour size on the efficacy of targeted alpha therapy with 213Bi-[DOTA0,Tyr3]-octreotate

Ho Sze Chan, Mark W. Konijnenberg, Erik de Blois, Stuart Koelewijn, Richard P. Baum, Alfred Morgenstern, Frank Bruchertseifer, Wouter A. Breeman, Marion de Jong

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Targeting of radiolabeled J591 antibody to PSMA-expressing tumors: optimization of imaging and therapy based on non-linear compartmental modeling

Edward K. Fung, Sarah M. Cheal, Shoaib B. Fareedy, Blesida Punzalan, Volkan Beylergil, Jawaria Amir, Sandhya Chalasani, Wolfgang A. Weber, Daniel E. Spratt, Darren R. Veach, Neil H. Bander, Steven M. Larson, Pat B. Zanzonico, Joseph R. Osborne

01.12.2016 | Erratum | Ausgabe 1/2016 Open Access

Erratum to: The ultimate radiochemical nightmare: upon radio-iodination of Botulinum neurotoxin A, the introduced iodine atom itself seems to be fatal for the bioactivity of this macromolecule

Janneke van Uhm

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

In vivo validation of gated myocardial SPECT imaging for quantification of small hearts: comparison with cardiac MRI

Chisato Kondo, Eri Watanabe, Mitsuru Momose, Kenji Fukushima, Koichiro Abe, Nobuhisa Hagiwara, Shuji Sakai

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Effects of erlotinib therapy on [11C]erlotinib uptake in EGFR mutated, advanced NSCLC

Idris Bahce, Maqsood Yaqub, Hanane Errami, Robert C. Schuit, Patrick Schober, Erik Thunnissen, Albert D. Windhorst, Adriaan A. Lammertsma, Egbert F. Smit, N. Harry Hendrikse

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Development of TASP0410457 (TASP457), a novel dihydroquinolinone derivative as a PET radioligand for central histamine H3 receptors

Kazumi Koga, Jun Maeda, Masaki Tokunaga, Masayuki Hanyu, Kazunori Kawamura, Mari Ohmichi, Toshio Nakamura, Yuji Nagai, Chie Seki, Yasuyuki Kimura, Takafumi Minamimoto, Ming-Rong Zhang, Toshimitsu Fukumura, Tetsuya Suhara, Makoto Higuchi

01.12.2016 | Original Research | Ausgabe 1/2016 Open Access

Radiolabeling polymeric micelles for in vivo evaluation: a novel, fast, and facile method

Adrianus C. Laan, Costanza Santini, Laurence Jennings, Marion de Jong, Monique R. Bernsen, Antonia G. Denkova

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Contribution of Auger/conversion electrons to renal side effects after radionuclide therapy: preclinical comparison of 161Tb-folate and 177Lu-folate

Stephanie Haller, Giovanni Pellegrini, Christiaan Vermeulen, Nicholas P. van der Meulen, Ulli Köster, Peter Bernhardt, Roger Schibli, Cristina Müller

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Optical imaging of pre-invasive breast cancer with a combination of VHHs targeting CAIX and HER2 increases contrast and facilitates tumour characterization

Marta M. Kijanka, Aram S. A. van Brussel, Elsken van der Wall, Willem P. T. M. Mali, Paul J. van Diest, Paul M. P. van Bergen en Henegouwen, Sabrina Oliveira

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Impact of clinically tested NEP/ACE inhibitors on tumor uptake of [111In-DOTA]MG11—first estimates for clinical translation

Aikaterini Kaloudi, Berthold A. Nock, Emmanouil Lymperis, Roelf Valkema, Eric P. Krenning, Marion de Jong, Theodosia Maina

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Quantitative accuracy of 177Lu SPECT reconstruction using different compensation methods: phantom and patient studies

Eero Hippeläinen, Mikko Tenhunen, Hanna Mäenpää, Antti Sohlberg

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Pre-clinical evaluation of eight DOTA coupled gastrin-releasing peptide receptor (GRP-R) ligands for in vivo targeting of receptor-expressing tumors

Antonella Accardo, Filippo Galli, Rosalba Mansi, Luigi Del Pozzo, Michela Aurilio, Anna Morisco, Paola Ringhieri, Alberto Signore, Giancarlo Morelli, Luigi Aloj

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Discovery and characterization of a high-affinity and high-specificity peptide ligand LXY30 for in vivo targeting of α3 integrin-expressing human tumors

Wenwu Xiao, Tianhong Li, Fernanda C. Bononi, Diana Lac, Ivy A. Kekessie, Yanlei Liu, Eduardo Sanchez, Anisha Mazloom, Ai-hong Ma, Jia Lin, Jimmy Tran, Kevin Yang, Kit S. Lam, Ruiwu Liu

01.12.2016 | Original Research | Ausgabe 1/2016 Open Access

An investigation of the relation between tumor-to-liver ratio (TLR) and tumor-to-blood standard uptake ratio (SUR) in oncological FDG PET

Frank Hofheinz, Rebecca Bütof, Ivayla Apostolova, Klaus Zöphel, Ingo G. Steffen, Holger Amthauer, Jörg Kotzerke, Michael Baumann, Jörg van den Hoff

01.12.2016 | Short communication | Ausgabe 1/2016 Open Access

Impact of MR-safe headphones on PET attenuation in combined PET/MRI scans

Florian Büther, Alexis Vrachimis, Anne Becker, Lars Stegger

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

For avid glucose tumors, the SUV peak is the most reliable parameter for [18F]FDG-PET/CT quantification, regardless of acquisition time

Avigaëlle Sher, Franck Lacoeuille, Pacôme Fosse, Laurent Vervueren, Aurélie Cahouet-Vannier, Djamel Dabli, Francis Bouchet, Olivier Couturier

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

ARAS: an automated radioactivity aliquoting system for dispensing solutions containing positron-emitting radioisotopes

Alex A. Dooraghi, Lewis Carroll, Jeffrey Collins, R. Michael van Dam, Arion F. Chatziioannou

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Automated Bone Scan Index as a quantitative imaging biomarker in metastatic castration-resistant prostate cancer patients being treated with enzalutamide

Aseem Anand, Michael J. Morris, Steven M. Larson, David Minarik, Andreas Josefsson, John T. Helgstrand, Peter S. Oturai, Lars Edenbrandt, Martin Andreas Røder, Anders Bjartell

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

A new method to quantify tau pathologies with 11C-PBB3 PET using reference tissue voxels extracted from brain cortical gray matter

Yasuyuki Kimura, Hironobu Endo, Masanori Ichise, Hitoshi Shimada, Chie Seki, Yoko Ikoma, Hitoshi Shinotoh, Makiko Yamada, Makoto Higuchi, Ming-Rong Zhang, Tetsuya Suhara

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Angiotensin II increases gene expression after selective intra-arterial adenovirus delivery in a rabbit model assessed using in vivo SSTR2-based reporter imaging

Sheela P. Singh, Murali K. Ravoori, Katherine A. Dixon, Lin Han, Sanjay Gupta, Rajesh Uthamanthil, Kenneth C. Wright, Vikas Kundra

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Engineering anti-Lewis-Y hu3S193 antibodies with improved therapeutic ratio for radioimmunotherapy of epithelial cancers

Ingrid J. G. Burvenich, Fook-Thean Lee, Graeme J. O’Keefe, Dahna Makris, Diana Cao, Sylvia Gong, Angela Rigopoulos, Laura C. Allan, Martin W. Brechbiel, Zhanqi Liu, Paul A. Ramsland, Andrew M. Scott

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Radioimmunotherapy of prostate cancer targeting human kallikrein-related peptidase 2

O. Vilhelmsson Timmermand, E. Larsson, D. Ulmert, T. A. Tran, SE. Strand

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Pharmacokinetic modeling of [18F]fluorodeoxyglucose (FDG) for premature infants, and newborns through 5-year-olds

Kitiwat Khamwan, Donika Plyku, Shannon E. O’Reilly, Alison Goodkind, Xinhua Cao, Frederic H. Fahey, S. Ted Treves, Wesley E. Bolch, George Sgouros

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

αVβ3 integrin-targeted microSPECT/CT imaging of inflamed atherosclerotic plaques in mice

David Vancraeynest, Véronique Roelants, Caroline Bouzin, François-Xavier Hanin, Stephan Walrand, Vanesa Bol, Anne Bol, Anne-Catherine Pouleur, Agnès Pasquet, Bernhard Gerber, Philippe Lesnik, Thierry Huby, François Jamar, Jean-Louis Vanoverschelde

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Dependence of treatment planning accuracy in peptide receptor radionuclide therapy on the sampling schedule

Christian Maaß, Jan Philipp Sachs, Deni Hardiansyah, Felix M. Mottaghy, Peter Kletting, Gerhard Glatting

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

[18F]FE@SNAP—a specific PET tracer for melanin-concentrating hormone receptor 1 imaging?

Cécile Philippe, Daniela Haeusler, Thomas Scherer, Clemens Fürnsinn, Markus Zeilinger, Wolfgang Wadsak, Karem Shanab, Helmut Spreitzer, Marcus Hacker, Markus Mitterhauser

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

An exploratory study of volumetric analysis for assessing tumor response with 18F-FAZA PET/CT in patients with advanced non-small-cell lung cancer (NSCLC)

Gerald S. M. A. Kerner, Vikram R. Bollineni, Thijo J. N. Hiltermann, Nanna M. Sijtsema, Alexander Fischer, Alphons H. H. Bongaerts, Jan Pruim, Harry J. M. Groen

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

[18F]tetrafluoroborate as a PET tracer for the sodium/iodide symporter: the importance of specific activity

Alex Khoshnevisan, Maite Jauregui-Osoro, Karen Shaw, Julia Baguña Torres, Jennifer D. Young, Nisha K. Ramakrishnan, Alex Jackson, Gareth E. Smith, Antony D. Gee, Philip J. Blower

01.12.2016 | Preliminary research | Ausgabe 1/2016 Open Access

Preclinical in vivo application of 152Tb-DOTANOC: a radiolanthanide for PET imaging

Cristina Müller, Christiaan Vermeulen, Karl Johnston, Ulli Köster, Raffaella Schmid, Andreas Türler, Nicholas P. van der Meulen

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

The influence of different metal-chelate conjugates of pentixafor on the CXCR4 affinity

Andreas Poschenrieder, Margret Schottelius, Markus Schwaiger, Horst Kessler, Hans-Jürgen Wester

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

PET imaging of cyclooxygenase-2 (COX-2) in a pre-clinical colorectal cancer model

Ole Tietz, Melinda Wuest, Alison Marshall, Darryl Glubrecht, Ingrit Hamann, Monica Wang, Cody Bergman, Jenilee D. Way, Frank Wuest

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Fluorescence imaging of in vivo miR-124a-induced neurogenesis of neuronal progenitor cells using neuron-specific reporters

Jaeho Jang, Song Lee, Hyun Jeong Oh, Yoori Choi, Jae Hyouk Choi, Do Won Hwang, Dong Soo Lee

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Calibration of PET/CT scanners for multicenter studies on differentiated thyroid cancer with 124I

Jakob W. Kist, Manfred van der Vlies, Otto S. Hoekstra, Henri N. J. M. Greuter, Bart de Keizer, Marcel P. M. Stokkel, Wouter V. Vogel, Marc C. Huisman, Arthur van Lingen

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Automated synthesis of [18F]DCFPyL via direct radiofluorination and validation in preclinical prostate cancer models

Vincent Bouvet, Melinda Wuest, Hans-Soenke Jans, Nancy Janzen, Afaf R. Genady, John F. Valliant, Francois Benard, Frank Wuest

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Accelerated 99mTc-sestamibi clearance associated with mitochondrial dysfunction and regional left ventricular dysfunction in reperfused myocardium in patients with acute coronary syndrome

Atsuro Masuda, Keiichiro Yoshinaga, Masanao Naya, Osamu Manabe, Satoshi Yamada, Hiroyuki Iwano, Tatsuya Okada, Chietsugu Katoh, Yasuchika Takeishi, Hiroyuki Tsutsui, Nagara Tamaki

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Posttreatment FDG PET/CT in predicting survival of patients with ovarian carcinoma

Linda C. Chu, Hua-Ling Tsai, Hao Wang, John Crandall, Mehrbod S. Javadi, Richard L. Wahl

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Evaluation of pulmonary perfusion by SPECT imaging using an endothelial cell tracer in supine humans and dogs

Xavier Levac, François Harel, Vincent Finnerty, Quang T. Nguyen, Myriam Letourneau, Sophie Marcil, Alain Fournier, Jocelyn Dupuis

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Comparison of LDPI to SPECT perfusion imaging using 99mTc-sestamibi and 99mTc-pyrophosphate in a murine ischemic hind limb model of neovascularization

Geert Hendrikx, Mark H. Vries, Matthias Bauwens, Marijke De Saint-Hubert, Allard Wagenaar, Joël Guillaume, Levinia Boonen, Mark J. Post, Felix M. Mottaghy

01.12.2016 | Short communication | Ausgabe 1/2016 Open Access

Correlation of clinical outcomes with bremsstrahlung and Y-90 PET/CT imaging findings following Y-90 radiosynoviorthesis: a prospective study

Thomas W. Barber, Martin H. Cherk, Anne Powell, Kenneth S. K. Yap, Baki Billah, Victor Kalff

01.12.2016 | Preliminary research | Ausgabe 1/2016 Open Access

18F-fluoride-PET for dynamic in vivo monitoring of bone formation in multiple myeloma

J. C. Regelink, P. G. Raijmakers, N. Bravenboer, R. Milek, N. J. Hoetjes, A. M. de Kreuk, M. van Duin, M. J. Wondergem, P. Lips, P. Sonneveld, J. M. Zijlstra, S. Zweegman

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Impact of attenuation correction on clinical [18F]FDG brain PET in combined PET/MRI

P. Werner, M. Rullmann, A. Bresch, S. Tiepolt, T. Jochimsen, D. Lobsien, M. L. Schroeter, O. Sabri, H. Barthel

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

The effect of dimethyl sulfoxide on the induction of DNA strand breaks in plasmid DNA and colony formation of PC Cl3 mammalian cells by alpha-, beta-, and Auger electron emitters 223Ra, 188Re, and 99mTc

Roswitha Runge, Liane Oehme, Jörg Kotzerke, Robert Freudenberg

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Somatostatin receptor scintigraphy in patients with rheumatoid arthritis and secondary Sjögren’s syndrome treated with Infliximab: a pilot study

L. K. Anzola-Fuentes, M. Chianelli, F. Galli, A. W. J. M. Glaudemans, L. Martin Martin, V. Todino, A. Migliore, A. Signore

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

177Lu-OPS201 targeting somatostatin receptors: in vivo biodistribution and dosimetry in a pig model

Seval Beykan, Jan S. Dam, Uta Eberlein, Jens Kaufmann, Benedict Kjærgaard, Lars Jødal, Hakim Bouterfa, Romain Bejot, Michael Lassmann, Svend Borup Jensen

01.12.2016 | Erratum | Ausgabe 1/2016 Open Access

Erratum to: Absorption, distribution and excretion of intravenously injected 68Ge/68Ga generator eluate in healthy rats, and estimation of human radiation dosimetry

Anu Autio, Helena Virtanen, Tuula Tolvanen, Heidi Liljenbäck, Vesa Oikonen, Tiina Saanijoki, Riikka Siitonen, Meeri Käkelä, Andrea Schüssele, Mika Teräs, Anne Roivainen

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

A dual tracer 68Ga-DOTANOC PET/CT and 18F-FDG PET/CT pilot study for detection of cardiac sarcoidosis

Lars C. Gormsen, Ate Haraldsen, Stine Kramer, Andre H. Dias, Won Yong Kim, Per Borghammer

01.12.2016 | Original Research | Ausgabe 1/2016 Open Access

Comparative evaluation of SUV, tumor-to-blood standard uptake ratio (SUR), and dual time point measurements for assessment of the metabolic uptake rate in FDG PET

Frank Hofheinz, Jörg van den Hoff, Ingo G. Steffen, Alexandr Lougovski, Kilian Ego, Holger Amthauer, Ivayla Apostolova

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Renal PET-imaging with 11C-metformin in a transgenic mouse model for chronic kidney disease

Lea Pedersen, Jonas Brorson Jensen, Lise Wogensen, Ole Lajord Munk, Niels Jessen, Jørgen Frøkiær, Steen Jakobsen

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Decreased renal AT1 receptor binding in rats after subtotal nephrectomy: PET study with [18F]FPyKYNE-losartan

Basma Ismail, Robert A. deKemp, Tayebeh Hadizad, Kumiko Mackasey, Rob S. Beanlands, Jean N. DaSilva

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Optimal 2-[18F]fluoro-2-deoxy-d-galactose PET/CT protocol for detection of hepatocellular carcinoma

Jacob Horsager, Kirstine Bak-Fredslund, Lars Peter Larsen, Gerda Elisabeth Villadsen, Trond Velde Bogsrud, Michael Sørensen

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Measuring total liver function on sulfur colloid SPECT/CT for improved risk stratification and outcome prediction of hepatocellular carcinoma patients

Stephen R. Bowen, Tobias R. Chapman, Joshua Borgman, Robert S. Miyaoka, Paul E. Kinahan, Iris W. Liou, George A. Sandison, Hubert J. Vesselle, Matthew J. Nyflot, Smith Apisarnthanarax

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Preclinical PET imaging of EGFR levels: pairing a targeting with a non-targeting Sel-tagged Affibody-based tracer to estimate the specific uptake

Qing Cheng, Helena Wållberg, Jonas Grafström, Li Lu, Jan-Olov Thorell, Maria Hägg Olofsson, Stig Linder, Katarina Johansson, Tetyana Tegnebratt, Elias S. J. Arnér, Sharon Stone-Elander, Hanna-Stina Martinsson Ahlzén, Stefan Ståhl, Sel-tag imaging project

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Preclinical modeling and multimodality imaging of chronic myocardial infarction in minipigs induced by novel interventional embolization technique

Bo Tao, Haokao Gao, Minwen Zheng, Zhonghua Luo, Liwen Liu, Wei Bai, Jing Wang, Daliang Liu, Sai Ma, Zhenli Luo, Lei Gao, Yabin Wang, Feng Cao

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Longitudinal analysis of bone metabolism using SPECT/CT and 99mTc-diphosphono-propanedicarboxylic acid: comparison of visual and quantitative analysis

Michael Beck, James C. Sanders, Philipp Ritt, Julia Reinfelder, Torsten Kuwert

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Fractal and multifractal analysis of PET/CT images of metastatic melanoma before and after treatment with ipilimumab

Christina-Marina Breki, Antonia Dimitrakopoulou-Strauss, Jessica Hassel, Theoharis Theoharis, Christos Sachpekidis, Leyun Pan, Astero Provata

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

The use of 18F-fluorodeoxyglucose positron emission tomography (18F-FDG PET) as a pathway-specific biomarker with AZD8186, a PI3Kβ/δ inhibitor

Juliana Maynard, Sally-Ann Emmas, Francois-Xavier Blé, Hervé Barjat, Emily Lawrie, Urs Hancox, Deborah Oakes, Urszula M. Polanska, Simon T. Barry

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

The relationship between endogenous thymidine concentrations and [18F]FLT uptake in a range of preclinical tumour models

Kathrin Heinzmann, Davina Jean Honess, David Yestin Lewis, Donna-Michelle Smith, Christopher Cawthorne, Heather Keen, Sandra Heskamp, Sonja Schelhaas, Timothy Howard Witney, Dmitry Soloviev, Kaye Janine Williams, Andreas Hans Jacobs, Eric Ofori Aboagye, John Richard Griffiths, Kevin Michael Brindle

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Nephroprotective effects of enalapril after [177Lu]-DOTATATE therapy using serial renal scintigraphies in a murine model of radiation-induced nephropathy

Harun Ilhan, Hao Wang, Franz J. Gildehaus, Carmen Wängler, Tanja Herrler, Andrei Todica, Julia Schlichtiger, Paul Cumming, Peter Bartenstein, Marcus Hacker, Alexander R. Haug

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

The effect of purification of Ga-68-labeled exendin on in vivo distribution

Maarten Brom, Gerben M. Franssen, Lieke Joosten, Martin Gotthardt, Otto C. Boerman

01.12.2016 | Erratum | Ausgabe 1/2016 Open Access

Erratum to: Toxicity and radiation dosimetry studies of the serotonin transporter radioligand [18F]AFM in rats and monkeys

Ya-Yao Huang, Cheng-Yi Cheng, Wen-Sheng Huang, Kuo-Hsing Ma, Ta-Wei Tseng, Ta-Kai Chou, Yiyun Huang, Chyng-Yann Shiue

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

The cingulate island sign within early Alzheimer’s disease-specific hypoperfusion volumes of interest is useful for differentiating Alzheimer’s disease from dementia with Lewy bodies

Etsuko Imabayashi, Kota Yokoyama, Tadashi Tsukamoto, Daichi Sone, Kaoru Sumida, Yukio Kimura, Noriko Sato, Miho Murata, Hiroshi Matsuda

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Quantification of myocardial blood flow with 82Rb: Validation with 15O-water using time-of-flight and point-spread-function modeling

Mary Germino, Jim Ropchan, Tim Mulnix, Kathryn Fontaine, Nabeel Nabulsi, Eric Ackah, Herman Feringa, Albert J. Sinusas, Chi Liu, Richard E. Carson

01.12.2016 | Editorial | Ausgabe 1/2016 Open Access

82Rb PET imaging of myocardial blood flow—have we achieved the 4 “R”s to support routine use?

Robert A. deKemp, Ran Klein, Rob S. B. Beanlands

01.12.2016 | Short Communication | Ausgabe 1/2016 Open Access

Preclinical evaluation of [68Ga]NOTA-pentixafor for PET imaging of CXCR4 expression in vivo — a comparison to [68Ga]pentixafor

Andreas Poschenrieder, Margret Schottelius, Markus Schwaiger, Hans-Jürgen Wester

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Inter-observer agreement improves with PERCIST 1.0 as opposed to qualitative evaluation in non-small cell lung cancer patients evaluated with F-18-FDG PET/CT early in the course of chemo-radiotherapy

Joan Fledelius, Azza Khalil, Karin Hjorthaug, Jørgen Frøkiær

01.12.2016 | Short communication | Ausgabe 1/2016 Open Access

Test-retest analysis of a non-invasive method of quantifying [11C]-PBR28 binding in Alzheimer’s disease

Akshay Nair, Mattia Veronese, Xiaohui Xu, Charles Curtis, Federico Turkheimer, Robert Howard, Suzanne Reeves

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

The role of FDG-PET/CT in preoperative staging of sentinel lymph node biopsy-positive melanoma patients

Evan C. Frary, Dorte Gad, Lars Bastholt, Søren Hess

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Early 18F-FDG uptake as a reliable imaging biomarker of T790M-mediated resistance but not MET amplification in non-small cell lung cancer treated with EGFR tyrosine kinase inhibitors

Viviana De Rosa, Francesca Iommelli, Marcello Monti, Ciro Gabriele Mainolfi, Rosa Fonti, Silvana Del Vecchio

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Comparison of the image-derived radioactivity and blood-sample radioactivity for estimating the clinical indicators of the efficacy of boron neutron capture therapy (BNCT): 4-borono-2-18F-fluoro-phenylalanine (FBPA) PET study

Kayako Isohashi, Eku Shimosegawa, Sadahiro Naka, Yasukazu Kanai, Genki Horitsugi, Ikuko Mochida, Keiko Matsunaga, Tadashi Watabe, Hiroki Kato, Mitsuaki Tatsumi, Jun Hatazawa

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Pilot study: use of gallium-68 PSMA PET for detection of metastatic lesions in patients with renal tumour

Handoo Rhee, John Blazak, Chui Ming Tham, Keng Lim Ng, Benjamin Shepherd, Malcolm Lawson, John Preston, Ian Vela, Paul Thomas, Simon Wood

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Cryopreservation of primary human monocytes does not negatively affect their functionality or their ability to be labelled with radionuclides: basis for molecular imaging and cell therapy

Evangelia Pardali, Timo Schmitz, Andreas Borgscheiper, Janette Iking, Lars Stegger, Johannes Waltenberger

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Impact of 68Ga-PSMA PET/CT on salvage radiotherapy planning in patients with prostate cancer and persisting PSA values or biochemical relapse after prostatectomy

Christina Bluemel, Fraenze Linke, Ken Herrmann, Iva Simunovic, Matthias Eiber, Christian Kestler, Andreas K. Buck, Andreas Schirbel, Thorsten A. Bley, Hans-Juergen Wester, Daniel Vergho, Axel Becker

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Reproducibility of 18F-fluoromisonidazole intratumour distribution in non-small cell lung cancer

Milan Grkovski, Jazmin Schwartz, Andreas Rimner, Heiko Schöder, Sean D. Carlin, Pat B. Zanzonico, John L. Humm, Sadek A. Nehmeh

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Effects of common anesthetic agents on [18F]flumazenil binding to the GABAA receptor

Mikael Palner, Corinne Beinat, Sam Banister, Francesca Zanderigo, Jun Hyung Park, Bin Shen, Trine Hjoernevik, Jae Ho Jung, Byung Chul Lee, Sang Eun Kim, Lawrence Fung, Frederick T. Chin

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Evaluation of 18F-fluorothymidine positron emission tomography ([18F]FLT-PET/CT) methodology in assessing early response to chemotherapy in patients with gastro-oesophageal cancer

R. Sharma, P. Mapelli, G. B. Hanna, R. Goldin, D. Power, A. Al-Nahhas, S. Merchant, R. Ramaswami, A. Challapalli, T. Barwick, E. O. Aboagye

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Effects of acetaminophen on mitochondrial complex I activity in the rat liver and kidney: a PET study with 18F-BCPP-BF

Hiroyuki Ohba, Masakatsu Kanazawa, Takeharu Kakiuchi, Hideo Tsukada

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Improved safety and efficacy of 213Bi-DOTATATE-targeted alpha therapy of somatostatin receptor-expressing neuroendocrine tumors in mice pre-treated with l-lysine

Ho Sze Chan, Mark W. Konijnenberg, Tamara Daniels, Monique Nysus, Mehran Makvandi, Erik de Blois, Wouter A. Breeman, Robert W. Atcher, Marion de Jong, Jeffrey P. Norenberg

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Predictive factors of 18F-choline PET/CT positivity in patients with prostate cancer recurrence after radiation therapy: is the impact of PSA nadir underestimated?

Alison C. Johnson, Audrey Emmanuelle Dugué, Marlon Silva, Laura Moise, Xavier Tillou, Florence Joly, Nicolas Aide

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Pre-clinical quantitative imaging and mouse-specific dosimetry for 111In-labelled radiotracers

Ana M. Denis-Bacelar, Sarah E. Cronin, Chiara Da Pieve, Rowena L. Paul, Sue A. Eccles, Terence J. Spinks, Carol Box, Adrian Hall, Jane K. Sosabowski, Gabriela Kramer-Marek, Glenn D. Flux

01.12.2016 | Original Research | Ausgabe 1/2016 Open Access

The effect of isoflurane on 18F-FDG uptake in the rat brain: a fully conscious dynamic PET study using motion compensation

Matthew G. Spangler-Bickell, Bart de Laat, Roger Fulton, Guy Bormans, Johan Nuyts

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

The clinical safety, biodistribution and internal radiation dosimetry of [18F]AH113804 in healthy adult volunteers

E. J. Somer, R. Owenius, A. Wall, G. Antoni, A. Thibblin, J. Sörensen

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

99mTc-labelled S-HYNIC certolizumab pegol in rheumatoid arthritis and spondyloarthritis patients: a biodistribution and dosimetry study

Bieke Lambert, Philippe Carron, Yves D’Asseler, Klaus Bacher, Filip Van den Bosch, Dirk Elewaut, Gust Verbruggen, Rudi Beyaert, Caroline Dumolyn, Filip De Vos

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Computational simulation of the predicted dosimetric impact of adjuvant yttrium-90 PET/CT-guided percutaneous ablation following radioembolization

Alexander S. Pasciak, Abigail Lin, Christos Georgiades, Laura K. Findeiss, Shannon Kauffman, Yong C. Bradley

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Dynamic PET evaluation of elevated FLT level after sorafenib treatment in mice bearing human renal cell carcinoma xenograft

Naoyuki Ukon, Songji Zhao, Wenwen Yu, Yoichi Shimizu, Ken-ichi Nishijima, Naoki Kubo, Yoshimasa Kitagawa, Nagara Tamaki, Kei Higashikawa, Hironobu Yasui, Yuji Kuge

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Low kidney uptake of GLP-1R-targeting, beta cell-specific PET tracer, 18F-labeled [Nle14,Lys40]exendin-4 analog, shows promise for clinical imaging

Kirsi Mikkola, Cheng-Bin Yim, Paula Lehtiniemi, Saila Kauhanen, Miikka Tarkia, Tuula Tolvanen, Pirjo Nuutila, Olof Solin

01.12.2016 | Original research | Ausgabe 1/2016 Open Access

Yttrium-90 radioembolization for colorectal cancer liver metastases: a prospective cohort study on circulating angiogenic factors and treatment response

C. E. N. M. Rosenbaum, A. F. van den Hoven, M. N. G. J. A. Braat, M. Koopman, M. G. E. H. Lam, B. A. Zonnenberg, H. M. Verkooijen, M. A. A. J. van den Bosch

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