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Zeitschrift

EJNMMI Research

EJNMMI Research 1/2020

Ausgabe 1/2020

Inhaltsverzeichnis ( 154 Artikel )

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

[18F]ML-10 PET imaging fails to assess early response to neoadjuvant chemotherapy in a preclinical model of triple negative breast cancer

Elodie Jouberton, Sébastien Schmitt, Emmanuel Chautard, Aurélie Maisonial-Besset, Marie Roy, Nina Radosevic-Robin, Jean-Michel Chezal, Elisabeth Miot-Noirault, Yann Bouvet, Florent Cachin

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Prognostic value of 99mTc-ECD brain perfusion SPECT in patients with atrial fibrillation and dementia

Hidenobu Hashimoto, Rine Nakanishi, Sunao Mizumura, Yukiko Hashimoto, Yuriko Okamura, Kyoko Yamanaka, Takanori Ikeda

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Biodistribution and imaging of an hsp90 ligand labelled with 111In and 67Ga for imaging of cell death

Ivan Ho Shon, Divesh Kumar, Chithradevi Sathiakumar, Paula Berghofer, Khang Van, Andrew Chicco, Philip J. Hogg

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Low-dose 18F-FDG TOF-PET/MR for accurate quantification of brown adipose tissue in healthy volunteers

Edwin E. G. W. ter Voert, Hanna Svirydenka, Julian Müller, Anton S. Becker, Miroslav Balaz, Vissarion Efthymiou, Claudia Irene Maushart, Gani Gashi, Christian Wolfrum, Matthias J. Betz, Irene A. Burger

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Pre-test 68Ga-PSMA-ligand PET/CT positivity in early biochemical recurrent prostate cancer after radical prostatectomy—validation of a prediction model

Pia Kraft, Tobias Maurer, Andrei Gafita, Markus Krönke, Bernhard Haller, Wolfgang A. Weber, Matthias Eiber, Isabel Rauscher

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

On the prevention of kidney uptake of radiolabeled DARPins

Mohamed Altai, Javad Garousi, Sara S. Rinne, Alexey Schulga, Sergey Deyev, Anzhelika Vorobyeva

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Quantitative 18F-FDG PET-CT scan characteristics correlate with tuberculosis treatment response

Stephanus T. Malherbe, Ray Y. Chen, Patrick Dupont, Ilse Kant, Magdalena Kriel, André G. Loxton, Bronwyn Smith, Caroline G. G. Beltran, Susan van Zyl, Shirely McAnda, Charmaine Abrahams, Elizna Maasdorp, Alex Doruyter, Laura E. Via, Clifton E. Barry III, David Alland, Stephanie Griffith- Richards, Annare Ellman, Thomas Peppard, John Belisle, Gerard Tromp, Katharina Ronacher, James M. Warwick, Jill Winter, Gerhard Walzl

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Myocardial perfusion reserve of kidney transplant patients is well preserved

Johanna Päivärinta, Kaj Metsärinne, Eliisa Löyttyniemi, Jarmo Teuho, Tuula Tolvanen, Juhani Knuuti, Niina Koivuviita

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Targeted alpha therapy with astatine-211-labeled anti-PSCA A11 minibody shows antitumor efficacy in prostate cancer xenografts and bone microtumors

Tom A. Bäck, Karin Jennbacken, Malin Hagberg Thulin, Sture Lindegren, Holger Jensen, Tove Olafsen, Paul J. Yazaki, Stig Palm, Per Albertsson, Jan-Erik Damber, Anna M. Wu, Karin Welén

01.12.2020 | Case report | Ausgabe 1/2020 Open Access

Paraneoplastic syndrome in undifferentiated embryonic sarcoma of the liver

Regine Mariette Perl, Almut Häring, Marius Stefan Horger, Christina Pfannenberg, Sergios Gatidis

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Kinetic modeling of 68Ga-PSMA-11 and validation of simplified methods for quantification in primary prostate cancer patients

Anna Ringheim, Guilherme de Carvalho Campos Neto, Udunna Anazodo, Lumeng Cui, Marcelo Livorsi da Cunha, Taise Vitor, Karine Minaif Martins, Ana Cláudia Camargo Miranda, Marycel Figols de Barboza, Leonardo Lima Fuscaldi, Gustavo Caserta Lemos, José Roberto Colombo Junior, Ronaldo Hueb Baroni

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Indium-111-labeled CD166-targeted peptide as a potential nuclear imaging agent for detecting colorectal cancer stem-like cells in a xenograft mouse model

Siao-Syun Guan, Cheng-Tien Wu, Tse-Zung Liao, Tsai-Yueh Luo, Kun-Liang Lin, Shing-Hwa Liu

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Optimization of PET protocol and interrater reliability of 18F-PSMA-11 imaging of prostate cancer

Sarah Piron, Kathia De Man, Vanessa Schelfhout, Nick Van Laeken, Ken Kersemans, Eric Achten, Filip De Vos, Piet Ost

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Interobserver agreement of [68Ga]Ga-PSMA-11 PET/CT images interpretation in men with newly diagnosed prostate cancer

Céline Derwael, Olivier Lavergne, Pierre Lovinfosse, Vlad Nechifor, Mallory Salvé, David Waltregny, Roland Hustinx, Nadia Withofs

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Design, synthesis, and biological evaluation of a multifunctional neuropeptide-Y conjugate for selective nuclear delivery of radiolanthanides

Adrien Chastel, Dennis J. Worm, Isabel D. Alves, Delphine Vimont, Melina Petrel, Samantha Fernandez, Philippe Garrigue, Philippe Fernandez, Elif Hindié, Annette G. Beck-Sickinger, Clément Morgat

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Results from extended lymphadenectomies with [111In]PSMA-617 for intraoperative detection of PSMA-PET/CT-positive nodal metastatic prostate cancer

Cordula A. Jilg, Kathrin Reichel, Christian Stoykow, H. Christian Rischke, Mark Bartholomä, Vanessa Drendel, Moritz von Büren, Wolfgang Schultze-Seemann, Philipp T. Meyer, Michael Mix

01.12.2020 | Preliminary research | Ausgabe 1/2020 Open Access

68Ga-PSMA PET/CT in radioactive iodine-refractory differentiated thyroid cancer and first treatment results with 177Lu-PSMA-617

Lisa H. de Vries, Lutske Lodewijk, Arthur J. A. T. Braat, Gerard C. Krijger, Gerlof D. Valk, Marnix G. E. H. Lam, Inne H. M. Borel Rinkes, Menno R. Vriens, Bart de Keizer

01.12.2020 | Short communication | Ausgabe 1/2020 Open Access

Quantification of [11C]PBR28 data after systemic lipopolysaccharide challenge

Eric A. Woodcock, Martin Schain, Kelly P. Cosgrove, Ansel T. Hillmer

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

PET quantification of brain O-GlcNAcase with [18F]LSN3316612 in healthy human volunteers

Jae-Hoon Lee, Jeih-San Liow, Soumen Paul, Cheryl L. Morse, Mohammad B. Haskali, Lester Manly, Sergey Shcherbinin, J. Craig Ruble, Nancy Kant, Emily C. Collins, Hugh N. Nuthall, Paolo Zanotti-Fregonara, Sami S. Zoghbi, Victor W. Pike, Robert B. Innis

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Kinetic analysis of HER2-binding ABY-025 Affibody molecule using dynamic PET in patients with metastatic breast cancer

Ali Alhuseinalkhudhur, Mark Lubberink, Henrik Lindman, Vladimir Tolmachev, Fredrik Y. Frejd, Joachim Feldwisch, Irina Velikyan, Jens Sörensen

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Quantitative γ-H2AX immunofluorescence method for DNA double-strand break analysis in testis and liver after intravenous administration of 111InCl3

Anna Stenvall, Erik Larsson, Bo Holmqvist, Sven-Erik Strand, Bo-Anders Jönsson

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Spinal cord hypermetabolism extends to skeletal muscle in amyotrophic lateral sclerosis: a computational approach to [18F]-fluorodeoxyglucose PET/CT images

Matteo Bauckneht, Rita Lai, Alberto Miceli, Daniela Schenone, Vanessa Cossu, Maria Isabella Donegani, Stefano Raffa, Anna Borra, Stefano Marra, Cristina Campi, Annamaria Orengo, Anna Maria Massone, Alberto Tagliafico, Claudia Caponnetto, Corrado Cabona, Angelina Cistaro, Adriano Chiò, Silvia Morbelli, Flavio Nobili, Gianmario Sambuceti, Michele Piana, Cecilia Marini

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Influence on [18F]FDG uptake by cancer cells after anti-PD-1 therapy in an enforced-immune activated mouse tumor

Mayu Tomita, Motofumi Suzuki, Yusuke Kono, Kohei Nakajima, Takuma Matsuda, Yuji Kuge, Mikako Ogawa

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Pharmacokinetics, radiation dosimetry, acute toxicity and automated synthesis of [18F]AmBF3-TATE

Joseph Lau, Jinhe Pan, Etienne Rousseau, Carlos F. Uribe, Sudhakara Reddy Seelam, Brent W. Sutherland, David M. Perrin, Kuo-Shyan Lin, François Bénard

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Accuracy in dosimetry of diagnostic agents: impact of the number of source tissues used in whole organ S value-based calculations

Anders Josefsson, Klaikangwol Siritantikorn, Sagar Ranka, Jose Willegaignon de Amorim de Carvalho, Carlos Alberto Buchpiguel, Marcelo Tatit Sapienza, Wesley E. Bolch, George Sgouros

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Standardized image quality for 68Ga-DOTA-TATE PET/CT

Christina P. W. Cox, Marcel Segbers, Laura H. Graven, Tessa Brabander, Daniëlle M. E. van Assema

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

HYPHYCA: a prospective study in 613 patients conducting a comprehensive analysis for predictive factors of physiological 18F-FDG anal uptake

Nicolas Aide, Laure-Eugénie Tainturier, Cathy Nganoa, Benjamin Houdu, Jennifer Kammerer, Marie-Pierre Galais, Renaud Ciappuccini, Charline Lasnon

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Coexistence of cerebral hypometabolism and neuroinflammation in the thalamo-limbic-brainstem region in young women with functional somatic syndrome

Takashi Matsudaira, Tatsuhiro Terada, Tomokazu Obi, Masamichi Yokokura, Yukitoshi Takahashi, Yasuomi Ouchi

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Multimodal analysis using [11C]PiB-PET/MRI for functional evaluation of patients with Alzheimer’s disease

Hidehiko Okazawa, Masamichi Ikawa, Minyoung Jung, Rikiya Maruyama, Tetsuya Tsujikawa, Tetsuya Mori, Mahmudur G. M. Rahman, Akira Makino, Yasushi Kiyono, Hirotaka Kosaka

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Added value of 68Ga-PSMA PET/CT for the detection of bone metastases in patients with newly diagnosed prostate cancer and a previous 99mTc bone scintigraphy

Helle D. Zacho, Søren Ravn, Ali Afshar-Oromieh, Joan Fledelius, June A. Ejlersen, Lars J. Petersen

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Radiation dosimetry of 18F-AzaFol: A first in-human use of a folate receptor PET tracer

Silvano Gnesin, Joachim Müller, Irene A. Burger, Alexander Meisel, Marco Siano, Martin Früh, Matthias Choschzick, Cristina Müller, Roger Schibli, Simon M. Ametamey, Philipp A. Kaufmann, Valerie Treyer, John O. Prior, Niklaus Schaefer

01.12.2020 | Review | Ausgabe 1/2020 Open Access

Hypoxia imaging and theranostic potential of [64Cu][Cu(ATSM)] and ionic Cu(II) salts: a review of current evidence and discussion of the retention mechanisms

Tengzhi Liu, Morten Karlsen, Anna Maria Karlberg, Kathrine Røe Redalen

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

[18F]Atorvastatin: synthesis of a potential molecular imaging tool for the assessment of statin-related mechanisms of action

Gonçalo S. Clemente, Jens Rickmeier, Inês F. Antunes, Tryfon Zarganes-Tzitzikas, Alexander Dömling, Tobias Ritter, Philip H. Elsinga

01.12.2020 | Commentary | Ausgabe 1/2020 Open Access

PRRT of neuroendocrine tumors: individualized dosimetry or fixed dose scheme?

Alexander R. Haug

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Comparative evaluation of 68Ga-labelled TATEs: the impact of chelators on imaging

Yuxiao Xia, Chengrun Zeng, Yanhong Zhao, Xinyi Zhang, Zibo Li, Yue Chen

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

A near-infrared probe for non-invasively monitoring cerebrospinal fluid flow by 18F-positron emitting tomography and fluorescence

Hua Guo, Harikrishna Kommidi, Carl C. Lekaye, Jason Koutcher, Martin S. Judenhofer, Simon R. Cherry, Amy P. Wu, Oguz Akin, Mark M. Souweidane, Omer Aras, Zhaohui Zhu, Richard Ting

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Enhancing the therapeutic effects of in vitro targeted radionuclide therapy of 3D multicellular tumor spheroids using the novel stapled MDM2/X-p53 antagonist PM2

Anja C. L. Mortensen, Eric Morin, Christopher J. Brown, David P. Lane, Marika Nestor

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Impaired brain glucose metabolism and presynaptic dopaminergic functioning in a mouse model of schizophrenia

Eugenia Tomasella, German Falasco, Leandro Urrutia, Lucila Bechelli, Lucia Padilla, Diego M. Gelman

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Visual and quantitative evaluation of [18F]FES and [18F]FDHT PET in patients with metastatic breast cancer: an interobserver variability study

Lemonitsa H. Mammatas, Clasina M. Venema, Carolina P. Schröder, Henrica C. W. de Vet, Michel van Kruchten, Andor W. J. M. Glaudemans, Maqsood M. Yaqub, Henk M. W. Verheul, Epie Boven, Bert van der Vegt, Erik F. J. de Vries, Elisabeth G. E. de Vries, Otto S. Hoekstra, Geke A. P. Hospers, C. Willemien Menke-van der Houven van Oordt

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Toxicity of a combined therapy using the mTOR-inhibitor everolimus and PRRT with [177Lu]Lu-DOTA-TATE in Lewis rats

Johannes Zellmer, Hsi-Yu Yen, Lena Kaiser, Erik Mille, Franz Josef Gildehaus, Guido Böning, Katja Steiger, Marcus Hacker, Peter Bartenstein, Andrei Todica, Alexander R. Haug, Harun Ilhan

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

A pan-cancer analysis of the clinical and genetic portraits of somatostatin receptor expressing tumor as a potential target of peptide receptor imaging and therapy

Hyunjong Lee, Minseok Suh, Hongyoon Choi, Seunggyun Ha, Jin Chul Paeng, Gi Jeong Cheon, Keon Wook Kang, Dong Soo Lee

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Double-strand breaks in lymphocyte DNA of humans exposed to [18F]fluorodeoxyglucose and the static magnetic field in PET/MRI

Gunnar Brix, Elisabeth Günther, Ute Rössler, David Endesfelder, Alexandra Kamp, Ambros Beer, Matthias Eiber

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Diagnostic value of PET/CT with 11C-methionine (MET) and 18F-fluorothymidine (FLT) in newly diagnosed glioma based on the 2016 WHO classification

Tomoya Ogawa, Nobuyuki Kawai, Keisuke Miyake, Aya Shinomiya, Yuka Yamamoto, Yoshihiro Nishiyama, Takashi Tamiya

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

[99cmTc]Tc-PSMA-I&S-SPECT/CT: experience in prostate cancer imaging in an outpatient center

P. Werner, C. Neumann, M. Eiber, H. J. Wester, M. Schottelius

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Targeted beta therapy of prostate cancer with 177Lu-labelled Miltuximab® antibody against glypican-1 (GPC-1)

Mei-Chun Yeh, Brian W. C. Tse, Nicholas L. Fletcher, Zachary H. Houston, Maria Lund, Marianna Volpert, Chelsea Stewart, Kamil A. Sokolowski, Varinder Jeet, Kristofer J. Thurecht, Douglas H. Campbell, Bradley J. Walsh, Colleen C. Nelson, Pamela J. Russell

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Head and neck tumors angiogenesis imaging with 68Ga-NODAGA-RGD in comparison to 18F-FDG PET/CT: a pilot study

Steve Durante, Vincent Dunet, François Gorostidi, Periklis Mitsakis, Niklaus Schaefer, Judith Delage, John O. Prior

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

VEGF receptor targeted imaging of angiogenic response to limb ischemia in diabetic vs. non-diabetic Yucatan minipigs

Lynne L. Johnson, Jordan Johnson, Ziad Ali, Yared Tekabe, Rebecca Ober, Gail Geist, Alicia McLuckie, Aram Safarov, April Holland, Geping Zhang, Marina Backer, Joseph Backer

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Fluorescence labeling of a NaV1.7-targeted peptide for near-infrared nerve visualization

Junior Gonzales, Giacomo Pirovano, Chun Yuen Chow, Paula Demetrio de Souza Franca, Lukas M. Carter, Julie K. Klint, Navjot Guru, Jason S. Lewis, Glenn F. King, Thomas Reiner

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Long-term Ashtanga yoga practice decreases medial temporal and brainstem glucose metabolism in relation to years of experience

June van Aalst, Jenny Ceccarini, Georg Schramm, Donatienne Van Weehaeghe, Ahmadreza Rezaei, Koen Demyttenaere, Stefan Sunaert, Koen Van Laere

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

PD-L1 expression correlation with metabolic parameters of FDG PET/CT and clinicopathological characteristics in non-small cell lung cancer

Xiaodong Wu, Yan Huang, Qingping Zhao, Lei Wang, Xiao Song, Yi Li, Lei Jiang

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Neuron-specific enolase has potential value as a biomarker for [18F]FDG/[68Ga]Ga-PSMA-11 PET mismatch findings in advanced mCRPC patients

Florian Rosar, Kalle Ribbat, Martin Ries, Johannes Linxweiler, Mark Bartholomä, Stephan Maus, Mathias Schreckenberger, Samer Ezziddin, Fadi Khreish

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Comparison of diagnostic sensitivity of [18F]fluoroestradiol and [18F]fluorodeoxyglucose positron emission tomography/computed tomography for breast cancer recurrence in patients with a history of estrogen receptor-positive primary breast cancer

Sun Young Chae, Hye Joo Son, Dong Yun Lee, Eonwoo Shin, Jungsu S. Oh, Seung Yeon Seo, Sora Baek, Ji Young Kim, Sae Jung Na, Dae Hyuk Moon

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Independent attenuation correction of whole body [18F]FDG-PET using a deep learning approach with Generative Adversarial Networks

Karim Armanious, Tobias Hepp, Thomas Küstner, Helmut Dittmann, Konstantin Nikolaou, Christian La Fougère, Bin Yang, Sergios Gatidis

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

High uptake of 68Ga-PSMA and 18F-DCFPyL in the peritumoral area of rat gliomas due to activated astrocytes

Dennis Oliveira, Carina Stegmayr, Alexander Heinzel, Johannes Ermert, Bernd Neumaier, N. Jon Shah, Felix M. Mottaghy, Karl-Josef Langen, Antje Willuweit

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Use of static and dynamic [18F]-F-DOPA PET parameters for detecting patients with glioma recurrence or progression

Timothée Zaragori, Merwan Ginet, Pierre-Yves Marie, Véronique Roch, Rachel Grignon, Guillaume Gauchotte, Fabien Rech, Marie Blonski, Zohra Lamiral, Luc Taillandier, Laëtitia Imbert, Antoine Verger

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

The flow-metabolism ratio might predict treatment response and survival in patients with locally advanced esophageal squamous cell carcinoma

Kewei Zhao, Chunsheng Wang, Qingfeng Mao, Dongping Shang, Yong Huang, Li Ma, Jinming Yu, Minghuan Li

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Synthesis of a novel 89Zr-labeled HER2 affibody and its application study in tumor PET imaging

Yuping Xu, Lizhen Wang, Donghui Pan, Junjie Yan, Xinyu Wang, Runlin Yang, Mingzhu Li, Yu Liu, Min Yang

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Quantification and reliability of [11C]VC - 002 binding to muscarinic acetylcholine receptors in the human lung — a test-retest PET study in control subjects

Zsolt Cselényi, Aurelija Jucaite, Cecilia Kristensson, Per Stenkrona, Pär Ewing, Andrea Varrone, Peter Johnström, Magnus Schou, Ana Vazquez-Romero, Mohammad Mahdi Moein, Martin Bolin, Jonathan Siikanen, Pär Grybäck, Bengt Larsson, Christer Halldin, Ken Grime, Ulf G. Eriksson, Lars Farde

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Regional SUV quantification in hybrid PET/MR, a comparison of two atlas-based automatic brain segmentation methods

Weiwei Ruan, Xun Sun, Xuehan Hu, Fang Liu, Fan Hu, Jinxia Guo, Yongxue Zhang, Xiaoli Lan

01.12.2020 | Original Research | Ausgabe 1/2020 Open Access

Human biodistribution and internal dosimetry of 4-[ 18F]fluorobenzyl-dexetimide: a PET radiopharmaceutical for imaging muscarinic acetylcholine receptors in the brain and heart

Cameron D. Pain, Graeme J. O’Keefe, Uwe Ackermann, Vincent Dore, Victor L. Villemagne, Christopher C. Rowe

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Voxel-based comparison of [68Ga]Ga-RM2-PET/CT and [68Ga]Ga-PSMA-11-PET/CT with histopathology for diagnosis of primary prostate cancer

Thomas Franz Fassbender, Florian Schiller, Constantinos Zamboglou, Vanessa Drendel, Selina Kiefer, Cordula A. Jilg, Anca-Ligia Grosu, Michael Mix

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Tumour-to-liver ratio determined by [68Ga]Ga-DOTA-TOC PET/CT as a prognostic factor of lanreotide efficacy for patients with well-differentiated gastroenteropancreatic-neuroendocrine tumours

Yong-il Kim, Changhoon Yoo, Seung Jun Oh, Sang Ju Lee, Junho Kang, Hee-Sang Hwang, Seung-Mo Hong, Baek-Yeol Ryoo, Jin-Sook Ryu

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Comparison of regional flortaucipir PET with quantitative tau immunohistochemistry in three subjects with Alzheimer’s disease pathology: a clinicopathological study

Michael J. Pontecorvo, C. Dirk Keene, Thomas G. Beach, Thomas J. Montine, Anupa K. Arora, Michael D. Devous Sr, Michael Navitsky, Ian Kennedy, Abhinay D. Joshi, Ming Lu, Geidy E. Serrano, Lucia I. Sue, Anthony J. Intorcia, Shannon E. Rose, Angela Wilson, Leanne Hellstern, Natalie Coleman, Matthew Flitter, Patricia Aldea, Adam S. Fleisher, Mark A. Mintun, Andrew Siderowf

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Cerenkov luminescence imaging is an effective preclinical tool for assessing colorectal cancer PD-L1 levels in vivo

Sheng Zhao, Wenbin Pan, Huijie Jiang, Rongjun Zhang, Hao Jiang, Zonghui Liang, Hongbo Hu

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

In vivo absolute quantification of striatal and extrastriatal D2/3 receptors with [123I]epidepride SPECT

Stergios Tsartsalis, Benjamin B. Tournier, Philippe Millet

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

PET imaging of soluble epoxide hydrolase in non-human primate brain with [18F]FNDP

Yong Du, Il Minn, Catherine Foss, Wojciech G. Lesniak, Feng Hu, Robert F. Dannals, Martin G. Pomper, Andrew G. Horti

01.12.2020 | Case report | Ausgabe 1/2020 Open Access

Extravasation of [177Lu]Lu-DOTATOC: case report and discussion

Anne Kirstine Arveschoug, Anne Charlotte Bekker, Peter Iversen, Henrik Bluhme, Gerda Elisabeth Villadsen, Peter Frøhlich Staanum

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

A preclinical PET dual-tracer imaging protocol for ER and HER2 phenotyping in breast cancer xenografts

Michel Paquette, Serge Phoenix, Christine Lawson, Brigitte Guérin, Roger Lecomte, Lee-Hwa Tai, Éric E. Turcotte, Jeffrey V. Leyton

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Translational strategy using multiple nuclear imaging biomarkers to evaluate target engagement and early therapeutic efficacy of SAR439859, a novel selective estrogen receptor degrader

Laurent Besret, Sébastien d’Heilly, Cathy Aubert, Guillaume Bluet, Florence Gruss-Leleu, Françoise Le-Gall, Anne Caron, Laurent Andrieu, Sylvie Vincent, Maysoun Shomali, Monsif Bouaboula, Carole Voland, Jeffrey Ming, Sébastien Roy, Srinivas Rao, Chantal Carrez, Erwan Jouannot

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Phantom and clinical evaluation of bone SPECT/CT image reconstruction with xSPECT algorithm

Noriaki Miyaji, Kenta Miwa, Ayaka Tokiwa, Hajime Ichikawa, Takashi Terauchi, Mitsuru Koizumi, Masahisa Onoguchi

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

[18F]FDG uptake of bone marrow on PET/CT for predicting distant recurrence in breast cancer patients after surgical resection

Jeong Won Lee, Sung Yong Kim, Sun Wook Han, Jong Eun Lee, Hyun Ju Lee, Nam Hun Heo, Sang Mi Lee

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Simultaneous in vivo PET/MRI using fluorine-18 labeled Fe3O4@Al(OH)3 nanoparticles: comparison of nanoparticle and nanoparticle-labeled stem cell distribution

Sarah Belderbos, Manuel Antonio González-Gómez, Frederik Cleeren, Jens Wouters, Yolanda Piñeiro, Christophe M. Deroose, An Coosemans, Willy Gsell, Guy Bormans, Jose Rivas, Uwe Himmelreich

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Development and validation of a prognostic model incorporating [18F]FDG PET/CT radiomics for patients with minor salivary gland carcinoma

Nai-Ming Cheng, Cheng-En Hsieh, Yu-Hua Dean Fang, Chun-Ta Liao, Shu-Hang Ng, Hung-Ming Wang, Wen-Chi Chou, Chien-Yu Lin, Tzu-Chen Yen

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Combined PET/CT with thoracic contrast-enhanced CT in assessment of primary cardiac tumors in adult patients

En-Tao Liu, Tao-Tao Sun, Hao-Jian Dong, Si-Yun Wang, Ze-Rui Chen, Chao Liu, Dan Shao, Zhou-Yang Lian, Qiu Xie, Shu-Xia Wang

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Mechanisms underlying the predictive power of high skeletal muscle uptake of FDG in amyotrophic lateral sclerosis

Cecilia Marini, Vanessa Cossu, Tiziana Bonifacino, Matteo Bauckneht, Carola Torazza, Silvia Bruno, Patrizia Castellani, Silvia Ravera, Marco Milanese, Consuelo Venturi, Sebastiano Carlone, Patrizia Piccioli, Laura Emionite, Silvia Morbelli, Anna Maria Orengo, Maria Isabella Donegani, Alberto Miceli, Stefano Raffa, Stefano Marra, Alessio Signori, Katia Cortese, Federica Grillo, Roberto Fiocca, Giambattista Bonanno, Gianmario Sambuceti

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Kinfitr — an open-source tool for reproducible PET modelling: validation and evaluation of test-retest reliability

Jonathan Tjerkaski, Simon Cervenka, Lars Farde, Granville James Matheson

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Selective serotonin reuptake inhibitors (SSRIs) prevent meta-iodobenzylguanidine (MIBG) uptake in platelets without affecting neuroblastoma tumor uptake

Thomas Blom, Rutger Meinsma, Marja Rutgers, Corine Buitenhuis, Marieke Dekken-Van den Burg, André B. P. van Kuilenburg, Godelieve A. M. Tytgat

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Radiobiological and dosimetric assessment of DNA-intercalated 99mTc-complexes bearing acridine orange derivatives

Ana Belchior, Salvatore Di Maria, Célia Fernandes, Pedro Vaz, António Paulo, Paula Raposinho

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Value of 18F-FDG PET/CT-based radiomics model to distinguish the growth patterns of early invasive lung adenocarcinoma manifesting as ground-glass opacity nodules

Xiaonan Shao, Rong Niu, Xiaoliang Shao, Zhenxing Jiang, Yuetao Wang

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

FDG PET versus CT radiomics to predict outcome in malignant pleural mesothelioma patients

M. Pavic, M. Bogowicz, J. Kraft, D. Vuong, M. Mayinger, S. G. C. Kroeze, M. Friess, T. Frauenfelder, N. Andratschke, M. Huellner, W. Weder, M. Guckenberger, S. Tanadini-Lang, I. Opitz

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Detection limit of 89Zr-labeled T cells for cellular tracking: an in vitro imaging approach using clinical PET/CT and PET/MRI

Laura M. Lechermann, Roido Manavaki, Bala Attili, Doreen Lau, Lorna B. Jarvis, Tim D. Fryer, Nick Bird, Luigi Aloj, Neel Patel, Bristi Basu, Matthew Cleveland, Franklin I. Aigbirhio, Joanne L. Jones, Ferdia A. Gallagher

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Human adult and adolescent biodistribution and dosimetry of the synaptic vesicle glycoprotein 2A radioligand 11C-UCB-J

Jason Bini, Daniel Holden, Kathryn Fontaine, Tim Mulnix, Yihuan Lu, David Matuskey, Jim Ropchan, Nabeel Nabulsi, Yiyun Huang, Richard E. Carson

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Automated synthesis, preclinical toxicity, and radiation dosimetry of [18F]MC225 for clinical use: a tracer for measuring P-glycoprotein function at the blood-brain barrier

Jun Toyohara, Muneyuki Sakata, Tetsuro Tago, Nicola A. Colabufo, Gert Luurtsema

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Comparison of [18F]FDG PET/CT with magnetic resonance imaging for the assessment of human brown adipose tissue activity

Jonas Gabriel William Fischer, Claudia Irene Maushart, Anton S. Becker, Julian Müller, Philipp Madoerin, Alin Chirindel, Damian Wild, Edwin E. G. W. ter Voert, Oliver Bieri, Irene Burger, Matthias Johannes Betz

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Correlation of positron emission tomography ventilation-perfusion matching with CT densitometry in severe emphysema

Asha Bonney, Carrie-Anne Wagner, Shankar Siva, Jason Callahan, Pierre-Yves Le Roux, Diane M. Pascoe, Louis Irving, Michael S. Hofman, Daniel P. Steinfort

01.12.2020 | Review | Ausgabe 1/2020 Open Access

Molecular imaging of the urokinase plasminogen activator receptor: opportunities beyond cancer

V. M. Baart, R. D. Houvast, L. F. de Geus-Oei, P. H. A. Quax, P. J. K. Kuppen, A. L. Vahrmeijer, C. F. M. Sier

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

18F-FDG PET and DCE kinetic modeling and their correlations in primary NSCLC: first voxel-wise correlative analysis of human simultaneous [18F]FDG PET-MRI data

Florent L. Besson, Brice Fernandez, Sylvain Faure, Olaf Mercier, Andrei Seferian, Xavier Mignard, Sacha Mussot, Cecile le Pechoux, Caroline Caramella, Angela Botticella, Antonin Levy, Florence Parent, Sophie Bulifon, David Montani, Delphine Mitilian, Elie Fadel, David Planchard, Benjamin Besse, Maria-Rosa Ghigna-Bellinzoni, Claude Comtat, Vincent Lebon, Emmanuel Durand

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Preliminary evidence of imaging of chemokine receptor-4-targeted PET/CT with [68Ga]pentixafor in non-Hodgkin lymphoma: comparison to [18F]FDG

Qingqing Pan, Yaping Luo, Yan Zhang, Long Chang, Ji Li, Xinxin Cao, Jian Li, Fang Li

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

A new 68Ga-labeled somatostatin analog containing two iodo-amino acids for dual somatostatin receptor subtype 2 and 5 targeting

Rosalba Mansi, Karim Abid, Guillaume P. Nicolas, Luigi Del Pozzo, Eric Grouzmann, Melpomeni Fani

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

[18F]FDG uptake of the normal spinal cord in PET/MR imaging: comparison with PET/CT imaging

Marco Aiello, Vincenzo Alfano, Elena Salvatore, Carlo Cavaliere, Marco Picardi, Roberta Della Pepa, Emanuele Nicolai, Andrea Soricelli, Alessandra Vella, Marco Salvatore, Mario Mascalchi

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

A DROP-IN beta probe for robot-assisted 68Ga-PSMA radioguided surgery: first ex vivo technology evaluation using prostate cancer specimens

Francesco Collamati, Matthias N. van Oosterom, Micol De Simoni, Riccardo Faccini, Marta Fischetti, Carlo Mancini Terracciano, Riccardo Mirabelli, Roberto Moretti, Judith olde Heuvel, Elena Solfaroli Camillocci, Florian van Beurden, Henk G. van der Poel, Renato A. Valdes Olmos, Pim J. van Leeuwen, Fijs W. B. van Leeuwen, Silvio Morganti

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

[18F]FEPPA PET imaging for monitoring CD68-positive microglia/macrophage neuroinflammation in nonhuman primates

Matthew Zammit, Yunlong Tao, Miles E. Olsen, Jeanette Metzger, Scott C. Vermilyea, Kathryn Bjornson, Maxim Slesarev, Walter F. Block, Kerri Fuchs, Sean Phillips, Viktorya Bondarenko, Su-Chun Zhang, Marina E. Emborg, Bradley T. Christian

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Quantitative comparison of pre-treatment predictive and post-treatment measured dosimetry for selective internal radiation therapy using cone-beam CT for tumor and liver perfusion territory definition

Esmaeel Jafargholi Rangraz, Xikai Tang, Charlotte Van Laeken, Geert Maleux, Jeroen Dekervel, Eric Van Cutsem, Chris Verslype, Kristof Baete, Johan Nuyts, Christophe M. Deroose

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Reliability of dopamine transporter PET measurements with [18F]FE-PE2I in patients with Parkinson’s disease

Vera S. Kerstens, Patrik Fazio, Mathias Sundgren, Granville J. Matheson, Erika Franzén, Christer Halldin, Simon Cervenka, Per Svenningsson, Andrea Varrone

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Yttrium-90 radioembolization as a possible new treatment for brain cancer: proof of concept and safety analysis in a canine model

Alexander S. Pasciak, Sasicha Manupipatpong, Ferdinand K. Hui, Larry Gainsburg, Rebecca Krimins, M. Christine Zink, Cory F. Brayton, Meaghan Morris, Jaime Sage, Danielle R. Donahue, Matthew R. Dreher, Dara L. Kraitchman, Clifford R. Weiss

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Quantification of [18F]afatinib using PET/CT in NSCLC patients: a feasibility study

E. A. van de Stadt, M. Yaqub, A. A. Lammertsma, A. J. Poot, P. R. Schober, R. C. Schuit, E. F. Smit, I. Bahce, N. H. Hendrikse

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

177Lu radiolabeling and preclinical theranostic study of 1C1m-Fc: an anti-TEM-1 scFv-Fc fusion protein in soft tissue sarcoma

J. A. Delage, A. Faivre-Chauvet, J. K. Fierle, S. Gnesin, N. Schaefer, G. Coukos, S. M. Dunn, D. Viertl, J. O. Prior

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Impact of the Q.Clear reconstruction algorithm on the interpretation of PET/CT images in patients with lymphoma

Michał Wyrzykowski, Natalia Siminiak, Maciej Kaźmierczak, Marek Ruchała, Rafał Czepczyński

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Initial evaluation of (4S)-4-(3-[18F]fluoropropyl)-l-glutamate (FSPG) PET/CT imaging in patients with head and neck cancer, colorectal cancer, or non-Hodgkin lymphoma

Sonya Y. Park, Camila Mosci, Meena Kumar, Mirwais Wardak, Norman Koglin, Santiago Bullich, Andre Mueller, Mathias Berndt, Andrew W. Stephens, Frederick T. Chin, Sanjiv S. Gambhir, Erik S. Mittra

01.12.2020 | Review | Ausgabe 1/2020 Open Access

Nuclear imaging methods for the prediction of postoperative morbidity and mortality in patients undergoing localized, liver-directed treatments: a systematic review

Caroline Espersen, Lise Borgwardt, Peter Nørgaard Larsen, Trine Borup Andersen, Louise Stenholt, Lars Jelstrup Petersen

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Predictive value of quantitative 18F-FDG-PET radiomics analysis in patients with head and neck squamous cell carcinoma

Roland M. Martens, Thomas Koopman, Daniel P. Noij, Elisabeth Pfaehler, Caroline Übelhör, Sughandi Sharma, Marije R. Vergeer, C. René Leemans, Otto S. Hoekstra, Maqsood Yaqub, Gerben J. Zwezerijnen, Martijn W. Heymans, Carel F. W. Peeters, Remco de Bree, Pim de Graaf, Jonas A. Castelijns, Ronald Boellaard

01.12.2020 | Short communication | Ausgabe 1/2020 Open Access

The feasibility of [18F]EF5-PET/CT to image hypoxia in ovarian tumors: a clinical study

Maren Laasik, Johanna Hynninen, Sarita Forsback, Tommi Noponen, Marko Seppänen, Sakari Hietanen

01.12.2020 | Correction | Ausgabe 1/2020 Open Access

Correction to: Yttrium-90 radioembolization as a possible new treatment for brain cancer: proof of concept and safety analysis in a canine model

Alexander S. Pasciak, Sasicha Manupipatpong, Ferdinand K. Hui, Larry Gainsburg, Rebecca Krimins, M. Christine Zink, Cory F. Brayton, Meaghan Morris, Jaime Sage, Danielle R. Donahue, Matthew R. Dreher, Dara L. Kraitchman, Clifford R. Weiss

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Convolutional neural networks for improving image quality with noisy PET data

Josh Schaefferkoetter, Jianhua Yan, Claudia Ortega, Andrew Sertic, Eli Lechtman, Yael Eshet, Ur Metser, Patrick Veit-Haibach

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

[68Ga]ABY-028: an albumin-binding domain (ABD) protein-based imaging tracer for positron emission tomography (PET) studies of altered vascular permeability and predictions of albumin-drug conjugate transport

Emma Jussing, Li Lu, Jonas Grafström, Tetyana Tegnebratt, Fabian Arnberg, Helena Wållberg Rosik, Anders Wennborg, Staffan Holmin, Joachim Feldwisch, Sharon Stone-Elander

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Mode of progression after radioembolization in patients with colorectal cancer liver metastases

Caren van Roekel, Jennifer M. J. Jongen, Maarten L. J. Smits, Sjoerd G. Elias, Miriam Koopman, Onno Kranenburg, Inne H. M. Borel Rinkes, Marnix G. E. H. Lam

01.12.2020 | Case report | Ausgabe 1/2020 Open Access

Neurologically asymptomatic cerebral oligometastatic prostate carcinoma metastasis identified on [Ga]Ga-THP-PSMA PET/CT

M. I. Ross, N. Bird, I. A. Mendichovszky, Y. L. Rimmer

01.12.2020 | Review | Ausgabe 1/2020 Open Access

Dealing with PET radiometabolites

Krishna Kanta Ghosh, Parasuraman Padmanabhan, Chang-Tong Yang, Sachin Mishra, Christer Halldin, Balázs Gulyás

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Baseline total metabolic tumor volume combined with international peripheral T-cell lymphoma project may improve prognostic stratification for patients with peripheral T-cell lymphoma (PTCL)

Chong Jiang, Yue Teng, Jieyu Chen, Zhen Wang, Zhengyang Zhou, Chongyang Ding, Jingyan Xu

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Fluorescent image-guided surgery in breast cancer by intravenous application of a quenched fluorescence activity-based probe for cysteine cathepsins in a syngeneic mouse model

Frans V. Suurs, Si-Qi Qiu, Joshua J. Yim, Carolien P. Schröder, Hetty Timmer-Bosscha, Eric S. Bensen, John T. Santini Jr, Elisabeth G. E. de Vries, Matthew Bogyo, Gooitzen M. van Dam

01.12.2020 | Short communication | Ausgabe 1/2020 Open Access

[18F]MPPF and [18F]FDG μPET imaging in rats: impact of transport and restraint stress

Verena Buchecker, Ann-Marie Waldron, R. Maarten van Dijk, Ines Koska, Matthias Brendel, Barbara von Ungern-Sternberg, Simon Lindner, Franz Josef Gildehaus, Sibylle Ziegler, Peter Bartenstein, Heidrun Potschka

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

TSPO PET detects acute neuroinflammation but not diffuse chronically activated MHCII microglia in the rat

Nassir U. Al-Khishman, Qi Qi, Austyn D. Roseborough, Alexander Levit, Brian L. Allman, Udunna C. Anazodo, Matthew S. Fox, Shawn N. Whitehead, Jonathan D. Thiessen

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

[11C]mHED PET follows a two-tissue compartment model in mouse myocardium with norepinephrine transporter (NET)-dependent uptake, while [18F]LMI1195 uptake is NET-independent

Linjing Mu, Stefanie D. Krämer, Geoffrey I. Warnock, Ahmed Haider, Susan Bengs, Giovanni Cartolano, Dominic S. Bräm, Claudia Keller, Roger Schibli, Simon M. Ametamey, Philipp A. Kaufmann, Catherine Gebhard

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Synthesis and evaluation of N-isopropyl-p-[11C]methylamphetamine as a novel cerebral blood flow tracer for positron emission tomography

Jun Toyohara, Norihiro Harada, Takeharu Kakiuchi, Hiroyuki Ohba, Masakatsu Kanazawa, Tetsuro Tago, Muneyuki Sakata, Kiichi Ishiwata

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

In vivo glucose metabolism and glutamate levels in mGluR5 knockout mice: a multimodal neuroimaging study using [18F]FDG microPET and MRS

Yo-Han Joo, Yun-Kwan Kim, In-Gyu Choi, Hyeon-Jin Kim, Young-Don Son, Hang-Keun Kim, Paul Cumming, Jong-Hoon Kim

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Diagnostic value of [18F]FDG PET/MRI for staging in patients with ovarian cancer

Hideaki Tsuyoshi, Tetsuya Tsujikawa, Shizuka Yamada, Hidehiko Okazawa, Yoshio Yoshida

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Quantitative evaluation of hepatic integrin αvβ3 expression by positron emission tomography imaging using 18F-FPP-RGD2 in rats with non-alcoholic steatohepatitis

Shuichi Hiroyama, Takemi Rokugawa, Miwa Ito, Hitoshi Iimori, Ippei Morita, Hiroki Maeda, Kae Fujisawa, Keiko Matsunaga, Eku Shimosegawa, Kohji Abe

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Longitudinal [18F]FDG-PET/CT analysis of the glucose metabolism in ApoE-deficient mice

Angela Kuhla, Lou Meuth, Jan Stenzel, Tobias Lindner, Chris Lappe, Jens Kurth, Bernd J. Krause, Stefan Teipel, Änne Glass, Guenther Kundt, Brigitte Vollmar

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Correlations between baseline 18F-FDG PET tumour parameters and circulating DNA in diffuse large B cell lymphoma and Hodgkin lymphoma

Pierre Decazes, Vincent Camus, Elodie Bohers, Pierre-Julien Viailly, Hervé Tilly, Philippe Ruminy, Mathieu Viennot, Sébastien Hapdey, Isabelle Gardin, Stéphanie Becker, Pierre Vera, Fabrice Jardin

01.12.2020 | Preliminary research | Ausgabe 1/2020 Open Access

Brain SPECT perfusion and PET metabolism as discordant biomarkers in major depressive disorder

Maud Tastevin, Laurent Boyer, Theo Korchia, Guillaume Fond, Christophe Lançon, Raphaëlle Richieri, Eric Guedj

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

[18F]FDG PET/CT for evaluating early response to neoadjuvant chemotherapy in pediatric patients with sarcoma: a prospective single-center trial

Giulia Polverari, Francesco Ceci, Roberto Passera, Jacquelyn Crane, Lin Du, Gang Li, Stefano Fanti, Nicholas Bernthal, Fritz C. Eilber, Martin Allen-Auerbach, Johannes Czernin, Jeremie Calais, Noah Federman

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

[11C]PIB amyloid quantification: effect of reference region selection

Fiona Heeman, Janine Hendriks, Isadora Lopes Alves, Rik Ossenkoppele, Nelleke Tolboom, Bart N. M. van Berckel, Adriaan A. Lammertsma, Maqsood Yaqub, on behalf of the AMYPAD Consortium

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Blocking of efflux transporters in rats improves translational validation of brain radioligands

Vladimir Shalgunov, Mengfei Xiong, Elina T. L’Estrade, Nakul R. Raval, Ida V. Andersen, Fraser G. Edgar, Nikolaj R. Speth, Simone L. Baerentzen, Hanne D. Hansen, Lene L. Donovan, Arafat Nasser, Siv T. Peitersen, Andreas Kjaer, Gitte M. Knudsen, Stina Syvänen, Mikael Palner, Matthias M. Herth

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Intraventricular synchronism assessment by gated-SPECT myocardial perfusion imaging in cardiac resynchronization therapy. Does cardiomyopathy type influence results?

Amalia Peix, Kenia Padrón, Lázaro O. Cabrera, Osmín Castañeda, Danet Milán, Jesús Castro, Roylan Falcón, Frank Martínez, Lydia Rodríguez, Jesús Sánchez, Erick Mena, Regla Carrillo, Yoel Fernández, Ricardo Escarano, Diana Páez, Maurizio Dondi

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

A novel PET tracer 18F-deoxy-thiamine: synthesis, metabolic kinetics, and evaluation on cerebral thiamine metabolism status

Changpeng Wang, Siwei Zhang, Yuefei Zou, Hongzhao Ma, Donglang Jiang, Lei Sheng, Shaoming Sang, Lirong Jin, Yihui Guan, Yuan Gui, Zhihong Xu, Chunjiu Zhong

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Brown adipose tissue uptake of triglyceride-rich lipoprotein-derived fatty acids in diabetic or obese mice under different temperature conditions

Andreas Paulus, Natascha Drude, Wouter van Marken Lichtenbelt, Felix M. Mottaghy, Matthias Bauwens

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Gallium-68 prostate-specific membrane antigen ([68Ga]Ga-PSMA-11) PET for imaging of thyroid cancer: a feasibility study

Courtney Lawhn-Heath, Sue S. Yom, Chienying Liu, Javier E. Villanueva-Meyer, Maya Aslam, Raven Smith, Manpreet Narwal, Roxanna Juarez, Spencer C. Behr, Miguel Hernandez Pampaloni, Jason W. Chan, Christine M. Glastonbury, Thomas A. Hope, Robert R. Flavell

01.12.2020 | Correction | Ausgabe 1/2020 Open Access

Correction to: Neurologically asymptomatic cerebral oligometastatic prostate carcinoma metastasis identified on [Ga]Ga-THP-PSMA PET/CT

M. I. Ross, N. Bird, I. A. Mendichovszky, Y. L. Rimmer

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

[177Lu]Lu-DOTA-ZOL bone pain palliation in patients with skeletal metastases from various cancers: efficacy and safety results

Madhav Prasad Yadav, Sanjana Ballal, Marian Meckel, Frank Roesch, Chandrasekhar Bal

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Metabolic network as an objective biomarker in monitoring deep brain stimulation for Parkinson’s disease: a longitudinal study

Jingjie Ge, Min Wang, Wei Lin, Ping Wu, Yihui Guan, Huiwei Zhang, Zhemin Huang, Likun Yang, Chuantao Zuo, Jiehui Jiang, Axel Rominger, Kuangyu Shi

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Day-to-day variability of [68Ga]Ga-PSMA-11 accumulation in primary prostate cancer: effects on tracer uptake and visual interpretation

Judith olde Heuvel, Berlinda J. de Wit-van der Veen, Maarten L. Donswijk, Cornelis H. Slump, Marcel P. M. Stokkel

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Tracking a TGF-β activator in vivo: sensitive PET imaging of αvβ8-integrin with the Ga-68-labeled cyclic RGD octapeptide trimer Ga-68-Triveoctin

Neil Gerard Quigley, Katja Steiger, Frauke Richter, Wilko Weichert, Sebastian Hoberück, Jörg Kotzerke, Johannes Notni

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Asphericity of tumor FDG uptake in non-small cell lung cancer: reproducibility and implications for harmonization in multicenter studies

Julian M. M. Rogasch, Christian Furth, Stephanie Bluemel, Piotr Radojewski, Holger Amthauer, Frank Hofheinz

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

[68Ga]Ga-PSMA-11 PET before and after initial long-term androgen deprivation in patients with newly diagnosed prostate cancer: a retrospective single-center study

Sebastian Hoberück, Steffen Löck, Robert Winzer, Klaus Zöphel, Michael Froehner, Dieter Fedders, Jörg Kotzerke, Tobias Hölscher

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Differences in [18F]FDG uptake in BAT of UCP1 −/− and UCP1 +/+ during adrenergic stimulation of non-shivering thermogenesis

Christian T. McHugh, John Garside, Jared Barkes, Jonathan Frank, Constance Dragicevich, Hong Yuan, Rosa T. Branca

01.12.2020 | Short communication | Ausgabe 1/2020 Open Access

Striatal dopamine transporter SPECT quantification: head-to-head comparison between two three-dimensional automatic tools

Silvia Morbelli, Dario Arnaldi, Eugenia Cella, Stefano Raffa, Maria Isabella Donegani, Selene Capitanio, Federico Massa, Alberto Miceli, Laura Filippi, Andrea Chincarini, Flavio Nobili

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

The value of 18F-PSMA-1007 PET/CT in identifying non-metastatic high-risk prostate cancer

Jun-jie Hong, Bo-le Liu, Zhi-qiang Wang, Kun Tang, Xiao-wei Ji, Wei-wei Yin, Jie Lin, Xiang-wu Zheng

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Evaluation of camera-based freehand SPECT in preoperative sentinel lymph node mapping for melanoma patients

Annie K. Kogler, Andrew M. Polemi, Surabhi Nair, Stanislaw Majewski, Lynn T. Dengel, Craig L. Slingluff Jr, Brian Kross, S. J. Lee, J. E. McKisson, John McKisson, Andrew G. Weisenberger, Benjamin L. Welch, Thomas Wendler, Philipp Matthies, Joerg Traub, Michael Witt, Mark B. Williams

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Sapap3 deletion causes dynamic synaptic density abnormalities: a longitudinal [11C]UCB-J PET study in a model of obsessive–compulsive disorder-like behaviour

Dorien Glorie, Jeroen Verhaeghe, Alan Miranda, Stef De Lombaerde, Sigrid Stroobants, Steven Staelens

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Plasma radio-metabolite analysis of PET tracers for dynamic PET imaging: TLC and autoradiography

Fiona Li, Justin W. Hicks, Lihai Yu, Lise Desjardin, Laura Morrison, Jennifer Hadway, Ting-Yim Lee

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

KRAS mutation effects on the 2-[18F]FDG PET uptake of colorectal adenocarcinoma metastases in the liver

M. Popovic, O. Talarico, J. van den Hoff, H. Kunin, Z. Zhang, D. Lafontaine, S. Dogan, J. Leung, E. Kaye, C. Czmielewski, M. E. Mayerhoefer, P. Zanzonico, R. Yaeger, H. Schöder, J. L. Humm, S. B. Solomon, C. T. Sofocleous, A. S. Kirov

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

18F-Fluciclovine PET metabolic imaging reveals prostate cancer tumour heterogeneity associated with disease resistance to androgen deprivation therapy

Gaurav Malviya, Rachana Patel, Mark Salji, Rafael S. Martinez, Peter Repiscak, Ernest Mui, Susan Champion, Agata Mrowinska, Emma Johnson, Maha AlRasheedi, Sally Pimlott, David Lewis, Hing Y. Leung

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Clinical impact of digital and conventional PET control databases for semi-quantitative analysis of brain 18F-FDG digital PET scans

Elise Mairal, Matthieu Doyen, Thérèse Rivasseau-Jonveaux, Catherine Malaplate, Eric Guedj, Antoine Verger

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Inter- and intraobserver agreement of the quantitative assessment of [99mTc]-labelled anti-programmed death-ligand 1 (PD-L1) SPECT/CT in non-small cell lung cancer

Daniel Johnathan Hughes, Gitasha Chand, Vicky Goh, Gary J. R. Cook

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Evaluation of [ 13 N]ammonia positron emission tomography as a potential method for quantifying glutamine synthetase activity in the human brain

Alice Egerton, Joel T. Dunn, Nisha Singh, Zilin Yu, Jim O’Doherty, Ivan Koychev, Jessica Webb, Simon Claridge, Federico E. Turkheimer, Paul K. Marsden, Alexander Hammers, Antony Gee

01.12.2020 | Short communication | Ausgabe 1/2020 Open Access

Specificity of translocator protein-targeted positron emission tomography in inflammatory joint disease

Yusuf Helo, Graham E. Searle, Federica Borghese, Sonya Abraham, Azeem Saleem

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

[18F]-Fluciclovine PET discrimination of recurrent intracranial metastatic disease from radiation necrosis

Ephraim E. Parent, Dhruv Patel, Jonathon A. Nye, Zhuo Li, Jeffrey J. Olson, David M. Schuster, Mark M. Goodman

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Preclinical comparison of four [18F, natGa]rhPSMA-7 isomers: influence of the stereoconfiguration on pharmacokinetics

Alexander Wurzer, Mara Parzinger, Matthias Konrad, Roswitha Beck, Thomas Günther, Veronika Felber, Stefanie Färber, Daniel Di Carlo, Hans-Jürgen Wester

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Relationship between tumor mutational burden and maximum standardized uptake value in 2-[18F]FDG PET (positron emission tomography) scan in cancer patients

Amin Haghighat Jahromi, Donald A. Barkauskas, Matthew Zabel, Aaron M. Goodman, Garret Frampton, Mina Nikanjam, Carl K. Hoh, Razelle Kurzrock

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

18F-C2Am: a targeted imaging agent for detecting tumor cell death in vivo using positron emission tomography

Flaviu Bulat, Friederike Hesse, De-En Hu, Susana Ros, Connor Willminton-Holmes, Bangwen Xie, Bala Attili, Dmitry Soloviev, Franklin Aigbirhio, Finian. J. Leeper, Kevin M. Brindle, André A. Neves

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Application of the PET ligand [11C]ORM-13070 to examine receptor occupancy by the α2C-adrenoceptor antagonist ORM-12741: translational validation of target engagement in rat and human brain

Mohammed Shahid, Juha O. Rinne, Mika Scheinin, Jere Virta, Päivi Marjamäki, Olof Solin, Eveliina Arponen, Jukka Sallinen, Katja Kuokkanen, Juha Rouru

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

Disease activity and response to therapy monitored by [18F]FDG PET/CT using volume-based indices in IgG4-related disease

Katsuya Mitamura, Hanae Arai-Okuda, Yuka Yamamoto, Takashi Norikane, Yasukage Takami, Kengo Fujimoto, Risa Wakiya, Hiroki Ozaki, Hiroaki Dobashi, Yoshihiro Nishiyama

01.12.2020 | Original research | Ausgabe 1/2020 Open Access

FLT-PET for the assessment of systemic sarcoidosis including cardiac and CNS involvement: a prospective study with comparison to FDG-PET

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01.12.2020 | Original research | Ausgabe 1/2020 Open Access

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