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Zeitschrift

EJNMMI Research

EJNMMI Research 1/2021

Ausgabe 1/2021

Inhaltsverzeichnis ( 109 Artikel )

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Clinical implementation of PLANET® Dose for dosimetric assessment after [177Lu]Lu-DOTA-TATE: comparison with Dosimetry Toolkit® and OLINDA/EXM® V1.0

Lore Santoro, L. Pitalot, D. Trauchessec, E. Mora-Ramirez, P. O. Kotzki, M. Bardiès, E. Deshayes

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Kinetic analysis of dominant intraprostatic lesion of prostate cancer using quantitative dynamic [18F]DCFPyL-PET: comparison to [18F]fluorocholine-PET

Dae-Myoung Yang, Fiona Li, Glenn Bauman, Joseph Chin, Stephen Pautler, Madeleine Moussa, Irina Rachinsky, John Valliant, Ting-Yim Lee

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

The significance of equivocal bone findings in staging PSMA imaging in the preoperative setting: validation of the PSMA-RADS version 1.0

Jonathan Kuten, Snir Dekalo, Ishai Mintz, Ofer Yossepowitch, Roy Mano, Einat Even-Sapir

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Repeatability of two semi-automatic artificial intelligence approaches for tumor segmentation in PET

Elisabeth Pfaehler, Liesbet Mesotten, Gem Kramer, Michiel Thomeer, Karolien Vanhove, Johan de Jong, Peter Adriaensens, Otto S. Hoekstra, Ronald Boellaard

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

The role of [68 Ga]Ga-DOTATATE PET/CT in wild-type KIT/PDGFRA gastrointestinal stromal tumours (GIST)

Luigi Aloj, Olivier Giger, Iosif A. Mendichovszky, Ben G. Challis, Meytar Ronel, Ines Harper, Heok Cheow, Rogier ten Hoopen, Deborah Pitfield, Ferdia A. Gallagher, Bala Attili, Mary McLean, Robin L. Jones, Palma Dileo, Venkata Ramesh Bulusu, Eamonn R. Maher, Ruth T. Casey

01.12.2021 | Review | Ausgabe 1/2021 Open Access

Nanobody: a promising toolkit for molecular imaging and disease therapy

Guangfa Bao, Ming Tang, Jun Zhao, Xiaohua Zhu

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Comparison of metabolic and functional parameters using cardiac 18F-FDG-PET in early to mid-adulthood male and female mice

Maximilian Fischer, Mathias J. Zacherl, Tobias Weinberger, Ludwig Weckbach, Bruno Huber, Christian Schulz, Steffen Massberg, Peter Bartenstein, Sebastian Lehner, Andrei Todica

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

A preliminary clinical trial to evaluate 64Cu-NOTA-Trastuzumab as a positron emission tomography imaging agent in patients with breast cancer

Inki Lee, Ilhan Lim, Byung Hyun Byun, Byung Il Kim, Chang Woon Choi, Sang-Keun Woo, Kwang Il Kim, Kyo Chul Lee, Joo Hyun Kang, Min-Ki Seong, Hyun-Ah Kim, Woo Chul Noh, Sang Moo Lim

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Preliminary study of AI-assisted diagnosis using FDG-PET/CT for axillary lymph node metastasis in patients with breast cancer

Zongyao Li, Kazuhiro Kitajima, Kenji Hirata, Ren Togo, Junki Takenaka, Yasuo Miyoshi, Kohsuke Kudo, Takahiro Ogawa, Miki Haseyama

01.12.2021 | Preliminary research | Ausgabe 1/2021 Open Access

Increased [18F]FMISO accumulation under hypoxia by multidrug-resistant protein 1 inhibitors

Yoichi Shimizu, Yukihiro Nakai, Hiroyuki Watanabe, Shimpei Iikuni, Masahiro Ono, Hideo Saji, Yuji Kuge, Tsuneo Saga, Yuji Nakamoto

01.12.2021 | Short communication | Ausgabe 1/2021 Open Access

A PSMA-targeted theranostic approach is unlikely to be efficient in serous ovarian cancers

Nicolas Aide, Laurent Poulain, Nicolas Elie, Mélanie Briand, Florence Giffard, Cécile Blanc-Fournier, Florence Joly, Charline Lasnon

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Potential synergy between PSMA uptake and tumour blood flow for prediction of human prostate cancer aggressiveness

Mads Ryø Jochumsen, Jens Sörensen, Lars Poulsen Tolbod, Bodil Ginnerup Pedersen, Jørgen Frøkiær, Michael Borre, Kirsten Bouchelouche

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Interim 4′-[methyl-11C]-thiothymidine PET for predicting the chemoradiotherapeutic response in head and neck squamous cell carcinoma: comparison with [18F]FDG PET

Katsuya Mitamura, Takashi Norikane, Yuka Yamamoto, Kengo Fujimoto, Yasukage Takami, Hiroshi Hoshikawa, Jun Toyohara, Yoshihiro Nishiyama

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Iodine-124 PET quantification of organ-specific delivery and expression of NIS-encoding RNA

Matthias Miederer, Stefanie Pektor, Isabelle Miederer, Nicole Bausbacher, Isabell Sofia Keil, Hossam Hefesha, Heinrich Haas, Ugur Sahin, Mustafa Diken

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Quantitation of cancer treatment response by 2-[18F]FDG PET/CT: multi-center assessment of measurement variability using AUTO-PERCIST™

Joo Hyun O, Su Jin Lim, Hao Wang, Jeffrey P. Leal, Hui-Kuo G. Shu, Richard L. Wahl, QIN PET Readers

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Comparison of 6-[18F]FDOPA PET with Nigrosome 1 detection in patients with parkinsonism

Enrico Michler, Daniel Kaiser, Kiriaki Eleftheriadou, Björn Falkenburger, Jörg Kotzerke, Sebastian Hoberück

01.12.2021 | Case report | Ausgabe 1/2021 Open Access

Yttrium-90 radioembolization of isolated hepatic adrenocortical carcinoma metastases with negative surgical pathology

Sen Lu, Jasreman Dhillon, Julie Hallanger Johnson, Ghassan El-Haddad

01.12.2021 | Review | Ausgabe 1/2021 Open Access

Clinical results of fibroblast activation protein (FAP) specific PET for non-malignant indications: systematic review

Paul Windisch, Daniel R. Zwahlen, Frederik L. Giesel, Eberhard Scholz, Patrick Lugenbiel, Jürgen Debus, Uwe Haberkorn, Sebastian Adeberg

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Preoperative prediction of pathological grade in pancreatic ductal adenocarcinoma based on 18F-FDG PET/CT radiomics

Haiqun Xing, Zhixin Hao, Wenjia Zhu, Dehui Sun, Jie Ding, Hui Zhang, Yu Liu, Li Huo

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Detection and therapy of neuroblastoma minimal residual disease using [64/67Cu]Cu-SARTATE in a preclinical model of hepatic metastases

Jason L. J. Dearling, Ellen M. van Dam, Matthew J. Harris, Alan B. Packard

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Evaluation of [68Ga]Ga-PSMA PET/CT images acquired with a reduced scan time duration in prostate cancer patients using the digital biograph vision

Manuel Weber, Walter Jentzen, Regina Hofferber, Ken Herrmann, Wolfgang Peter Fendler, Maurizio Conti, Axel Wetter, David Kersting, Christoph Rischpler, Pedro Fragoso Costa

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

99mTc-labelled PSMA ligand for radio-guided surgery in nodal metastatic prostate cancer: proof of principle

Michael Mix, Wolfgang Schultze-Seemann, Moritz von Büren, August Sigle, Mohamed A. Omrane, Markus T. Grabbert, Martin Werner, Christian Gratzke, Philipp T. Meyer, Cordula A. Jilg

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

The joint use of 99mTc-MAA-SPECT/CT and cone-beam CT optimizes radioembolization planning

Macarena Rodríguez-Fraile, Ana Ezponda, Fabiana Grisanti, Verónica Morán, Marta Calvo, Pablo Berián, Antonio Martínez de la Cuesta, Lidia Sancho, Mercedes Iñarrairaegui, Bruno Sangro, José Ignacio Bilbao

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Impact of contouring methods on pre-treatment and post-treatment dosimetry for the prediction of tumor control and survival in HCC patients treated with selective internal radiation therapy

Guillaume Nodari, Romain Popoff, Jean Marc Riedinger, Olivier Lopez, Julie Pellegrinelli, Inna Dygai-Cochet, Claire Tabouret-Viaud, Benoit Presles, Olivier Chevallier, Sophie Gehin, Matthieu Gallet, Marianne Latournerie, Sylvain Manfredi, Romaric Loffroy, Jean Marc Vrigneaud, Alexandre Cochet

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Muscarinic inhibition of salivary glands with glycopyrronium bromide does not reduce the uptake of PSMA-ligands or radioiodine

V. Mohan, N. M. Bruin, M. E. T. Tesselaar, J. P. de Boer, E. Vegt, J. J. M. A. Hendrikx, A. Al-Mamgani, J. B. van de Kamer, J.-J. Sonke, W. V. Vogel

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

GMP-compliant fully automated radiosynthesis of [18F]FEPPA for PET/MRI imaging of regional brain TSPO expression

Chi-Wei Chang, Chuang-Hsin Chiu, Ming-Hsien Lin, Hung-Ming Wu, Tsung-Hsun Yu, Pao-Yeh Wang, Yu-Yeh Kuo, Ya-Yao Huang, Chyng-Yann Shiue, Wen-Sheng Huang, Skye Hsin-Hsien Yeh

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Autoradiographical assessment of inflammation-targeting radioligands for atherosclerosis imaging: potential for plaque phenotype identification

Eric J. Meester, Erik de Blois, Boudewijn J. Krenning, Antonius F. W. van der Steen, Jeff P. Norenberg, Kim van Gaalen, Monique R. Bernsen, Marion de Jong, Kim van der Heiden

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Intraoperative [18F]FDG flexible autoradiography for tumour margin assessment in breast-conserving surgery: a first-in-human multicentre feasibility study

Patriek A. G. T. Jurrius, Maarten R. Grootendorst, Marika Krotewicz, Massimiliano Cariati, Ashutosh Kothari, Neill Patani, Paulina Karcz, Monika Nagadowska, Kunal N. Vyas, Arnie Purushotham, Maria Turska-d’Amico

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Prognostic superiority of International Prognostic Index over [18F]FDG PET/CT volumetric parameters in post-transplant lymphoproliferative disorder

F. Montes de Jesus, D. Dierickx, V. Vergote, W. Noordzij, R. A. J. O. Dierckx, C. M. Deroose, A. W. J. M. Glaudemans, O. Gheysens, T. C. Kwee

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Carotid plaque inflammatory activity assessed by 2-[18F]FDG-PET imaging decrease after a neurological thromboembolic event

Laerke Urbak, Rasmus S. Ripa, Benjamin V. Sandholt, Andreas Kjaer, Henrik Sillesen, Martin Graebe

01.12.2021 | Short communication | Ausgabe 1/2021 Open Access

The pons as reference region for intensity normalization in semi-quantitative analysis of brain 18FDG PET: application to metabolic changes related to ageing in conventional and digital control databases

A. Verger, M. Doyen, J. Y. Campion, Eric Guedj

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

A retrospective analysis of the diagnostic performance of 11C-choline PET/CT for detection of hyperfunctioning parathyroid glands after prior negative or discordant imaging in primary hyperparathyroidism

M. E. Noltes, S. Kruijff, L. Jansen, H. E. Westerlaan, W. T. Zandee, R. A. J. O. Dierckx, A. H. Brouwers

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Prospective data-driven respiratory gating of [68Ga]Ga-DOTATOC PET/CT

Jonathan Sigfridsson, Elin Lindström, Victor Iyer, Maria Holstensson, Irina Velikyan, Anders Sundin, Mark Lubberink

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Can the function of the tubarial glands be evaluated using [99mTc]pertechnetate SPECT/CT, [18F]FDG PET/CT, and [11C]methionine PET/CT?

Yohji Matsusaka, Tomohiko Yamane, Kenji Fukushima, Akira Seto, Ichiro Matsunari, Ichiei Kuji

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Region- and voxel-based quantification in human brain of [18F]LSN3316612, a radioligand for O-GlcNAcase

Jae-Hoon Lee, Mattia Veronese, Jeih-San Liow, Cheryl L. Morse, Jose A. Montero Santamaria, Mohammad B. Haskali, Sami S. Zoghbi, Victor W. Pike, Robert B. Innis, Paolo Zanotti-Fregonara

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

The pharmacokinetics of [18F]UCB-H revisited in the healthy non-human primate brain

Sébastien Goutal, Martine Guillermier, Guillaume Becker, Mylène Gaudin, Yann Bramoullé, André Luxen, Christian Lemaire, Alain Plenevaux, Eric Salmon, Philippe Hantraye, Olivier Barret, Nadja Van Camp

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Angiogenesis imaging study using interim [18F] RGD-K5 PET/CT in patients with lymphoma undergoing chemotherapy: preliminary evidence

David Tonnelet, M. D. Pierre Bohn, Stephanie Becker, Pierre Decazes, Vincent Camus, Sebastien Thureau, Hervé Tilly, Fabrice Jardin, Pierre Vera

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Comparison of FDG and FMISO uptakes and distributions in head and neck squamous cell cancer tumors

Sadek A. Nehmeh, Mohamed B. Moussa, Nancy Lee, Pat Zanzonico, Mithat Gönen, John L. Humm, Heiko Schöder

01.12.2021 | Editorial | Ausgabe 1/2021 Open Access

10 years of EJNMMI Research: an overview

Angelika Bischof Delaloye

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Correlation of [18F]florbetaben textural features and age of onset of Alzheimer’s disease: a principal components analysis approach

Jing Li, Emanuele Antonecchia, Marco Camerlenghi, Agostino Chiaravalloti, Qian Chu, Alfonso Di Costanzo, Zhen Li, Lin Wan, Xiangsong Zhang, Nicola D’Ascenzo, Orazio Schillaci, Qingguo Xie

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Parameters predicting [18F]PSMA-1007 scan positivity and type and number of detected lesions in patients with biochemical recurrence of prostate cancer

Niloefar Ahmadi Bidakhvidi, Annouschka Laenen, Sander Jentjens, Christophe M. Deroose, Koen Van Laere, Liesbeth De Wever, Cindy Mai, Charlien Berghen, Gert De Meerleer, Karin Haustermans, Steven Joniau, Wouter Everaerts, Karolien Goffin

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Correlation of 4′-[methyl-11C]-thiothymidine PET with Gd-enhanced and FLAIR MRI in patients with newly diagnosed glioma

Takashi Norikane, Katsuya Mitamura, Yuka Yamamoto, Yukito Maeda, Kenichi Tanaka, Tetsuhiro Hatakeyama, Keisuke Miyake, Jun Toyohara, Yoshihiro Nishiyama

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Head to head comparison of [99mTc]Tc(CO)3(NTA) and [99mTc]Tc-MAG3 in patients with suspected obstruction

Andrew T. Taylor, Malgorzata Lipowska, Raghuveer K. Halkar

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Feasibility of equivalent performance of 3D TOF [18F]-FDG PET/CT with reduced acquisition time using clinical and semiquantitative parameters

Julia Pilz, Lukas Hehenwarter, Georg Zimmermann, Gundula Rendl, Gregor Schweighofer-Zwink, Mohsen Beheshti, Christian Pirich

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

In vitro and pilot in vivo imaging of 18 kDa translocator protein (TSPO) in inflammatory vascular disease

Romain Schollhammer, Sébastien Lepreux, Nicole Barthe, Delphine Vimont, Anne Rullier, Igor Sibon, Xavier Berard, Andrea Zhang, Yasuyuki Kimura, Masahiro Fujita, Robert B. Innis, Paolo Zanotti-Fregonara, Clément Morgat

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Conscious rat PET imaging with soft immobilization for quantitation of brain functions: comprehensive assessment of anesthesia effects on cerebral blood flow and metabolism

Chie Suzuki, Mutsumi Kosugi, Yasuhiro Magata

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Necrosis binding of Ac-Lys0(IRDye800CW)-Tyr3-octreotate: a consequence from cyanine-labeling of small molecules

Marcus C. M. Stroet, Bianca M. Dijkstra, Sebastiaan E. Dulfer, Schelto Kruijff, Wilfred F. A. den Dunnen, Frank A. E. Kruyt, Rob J. M. Groen, Yann Seimbille, Kranthi M. Panth, Laura Mezzanotte, Clemens W. G. M. Lowik, Marion de Jong

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Post-reconstruction enhancement of [18F]FDG PET images with a convolutional neural network

John Ly, David Minarik, Jonas Jögi, Per Wollmer, Elin Trägårdh

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

A dual-time-window protocol to reduce acquisition time of dynamic tau PET imaging using [18F]MK-6240

Guilherme D. Kolinger, David Vállez García, Talakad G. Lohith, Eric D. Hostetler, Cyrille Sur, Arie Struyk, Ronald Boellaard, Michel Koole

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Intraoperative visualization of nerves using a myelin protein-zero specific fluorescent tracer

Tessa Buckle, Albertus. W. Hensbergen, Danny M. van Willigen, Frank Bosse, Kevin Bauwens, Rob C. M. Pelger, Fijs W. B. van Leeuwen

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Prognostic value of baseline interleukin 6 levels in liver decompensation and survival in HCC patients undergoing radioembolization

Osman Öcal, Juozas Kupčinskas, Egidijus Morkunas, Holger Amthauer, Kerstin Schütte, Peter Malfertheiner, Heinz Josef Klümpen, Christian Sengel, Julia Benckert, Ricarda Seidensticker, Bruno Sangro, Moritz Wildgruber, Maciej Pech, Peter Bartenstein, Jens Ricke, Max Seidensticker

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

A three-stage, deep learning, ensemble approach for prognosis in patients with Parkinson’s disease

Kevin H. Leung, Steven P. Rowe, Martin G. Pomper, Yong Du

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Automated and robust organ segmentation for 3D-based internal dose calculation

Mahmood Nazari, Luis David Jiménez-Franco, Michael Schroeder, Andreas Kluge, Marcus Bronzel, Sharok Kimiaei

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Risk factors for nonvisualization of the sentinel lymph node on lymphoscintigraphy in breast cancer patients

Youssef Chahid, Xinbo Qiu, Ewoudt M. W. van de Garde, Hein J. Verberne, Jan Booij

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Evaluation of 18F-AlF-NOTA-octreotide for imaging neuroendocrine neoplasms: comparison with 68Ga-DOTATATE PET/CT

Jiale Hou, Tingting Long, Zhiyou He, Ming Zhou, Nengan Yang, Dengming Chen, Shan Zeng, Shuo Hu

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Deep learning-based amyloid PET positivity classification model in the Alzheimer’s disease continuum by using 2-[18F]FDG PET

Suhong Kim, Peter Lee, Kyeong Taek Oh, Min Soo Byun, Dahyun Yi, Jun Ho Lee, Yu Kyeong Kim, Byoung Seok Ye, Mi Jin Yun, Dong Young Lee, Yong Jeong, the Alzheimer’s Disease Neuroimaging Initiative, the KBASE Research Group

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Performance of nanoScan PET/CT and PET/MR for quantitative imaging of 18F and 89Zr as compared with ex vivo biodistribution in tumor-bearing mice

Marion Chomet, Maxime Schreurs, Ricardo Vos, Mariska Verlaan, Esther J. Kooijman, Alex J. Poot, Ronald Boellaard, Albert D. Windhorst, Guus AMS van Dongen, Danielle J. Vugts, Marc C. Huisman, Wissam Beaino

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

The association of DAT gene methylation with striatal DAT availability in healthy subjects

Kyoungjune Pak, Ju Won Seok, Hyun-Yeol Nam, Seongho Seo, Myung Jun Lee, Keunyoung Kim, In Joo Kim

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

[99mTc]Tc-Galacto-RGD2 integrin αvβ3-targeted imaging as a surrogate for molecular phenotyping in lung cancer: real-world data

Jingjing Fu, Yan Xie, Tong Fu, Fan Qiu, Fei Yu, Wei Qu, Xiaochen Yao, Aiping Zhang, Zhenhua Yang, Guoqiang Shao, Qingle Meng, Xiumin Shi, Yue Huang, Wei Gu, Feng Wang

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Accuracy comparison of various quantitative [99mTc]Tc-DPD SPECT/CT reconstruction techniques in patients with symptomatic hip and knee joint prostheses

Martin Braun, Michal Cachovan, Felix Kaul, Federico Caobelli, Markus Bäumer, A. Hans Vija, Geert Pagenstert, Damian Wild, Martin Kretzschmar

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Hematologic safety of 177Lu-PSMA-617 radioligand therapy in patients with metastatic castration-resistant prostate cancer

Daniel Groener, Cam Tu Nguyen, Justus Baumgarten, Benjamin Bockisch, Karen Davis, Christian Happel, Nicolai Mader, Christina Nguyen Ngoc, Jennifer Wichert, Severine Banek, Philipp Mandel, Felix K. H. Chun, Nikolaos Tselis, Frank Grünwald, Amir Sabet

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Whole-body [18F]-FDG-PET/MRI for staging of pediatric non-Hodgkin lymphoma: first results from a single-center evaluation

L. Kurch, R. Kluge, O. Sabri, L. Fischer, S. Wendt, H. Graf Einsiedel, S. Starke, J.-S. Kühl, H. Christiansen, F. W. Hirsch, I. Sorge, C. Roth

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

In vitro proof of concept studies of radiotoxicity from Auger electron-emitter thallium-201

Katarzyna M. Osytek, Philip J. Blower, Ines M. Costa, Gareth E. Smith, Vincenzo Abbate, Samantha Y. A. Terry

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Prognostic value of baseline total metabolic tumour volume of 18F-FDG PET/CT imaging in patients with angioimmunoblastic T-cell lymphoma

Huanyu Gong, Tiannv Li, Jianyong Li, Lijun Tang, Chongyang Ding

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

A dedicated paediatric [18F]FDG PET/CT dosage regimen

Christina P. W. Cox, Daniëlle M. E. van Assema, Frederik A. Verburg, Tessa Brabander, Mark Konijnenberg, Marcel Segbers

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Competitive blocking of salivary gland [18F]DCFPyL uptake via localized, retrograde ductal injection of non-radioactive DCFPyL: a preclinical study

Jyoti Roy, Blake M. Warner, Falguni Basuli, Xiang Zhang, Changyu Zheng, Corrine Goldsmith, Tim Phelps, Karen Wong, Anita T. Ton, Rick Pieschl, Margaret E. White, Rolf Swenson, John A. Chiorini, Peter L. Choyke, Frank I. Lin

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Hypoxia and glucose metabolism assessed by FMISO and FDG PET for predicting IDH1 mutation and 1p/19q codeletion status in newly diagnosed malignant gliomas

Kenta Suzuki, Nobuyuki Kawai, Tomoya Ogawa, Keisuke Miyake, Aya Shinomiya, Yuka Yamamoto, Yoshihiro Nishiyama, Takashi Tamiya

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

N-staging in large cell neuroendocrine carcinoma of the lung: diagnostic value of [18F]FDG PET/CT compared to the histopathology reference standard

Hubertus Hautzel, Yazan Alnajdawi, Wolfgang P. Fendler, Christoph Rischpler, Kaid Darwiche, Wilfried E. Eberhardt, Lale Umutlu, Dirk Theegarten, Martin Stuschke, Martin Schuler, Clemens Aigner, Ken Herrmann, Till Plönes

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Automated procedure assessing the accuracy of HRCT–PET registration applied in functional virtual bronchoscopy

Gábor Opposits, Marianna Nagy, Zoltán Barta, Csaba Aranyi, Dániel Szabó, Attila Makai, Imre Varga, László Galuska, Lajos Trón, László Balkay, Miklós Emri

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

[18F]FDG PET/MRI enables early chemotherapy response prediction in pancreatic ductal adenocarcinoma

Felix N. Harder, Friederike Jungmann, Georgios A. Kaissis, Fabian K. Lohöfer, Sebastian Ziegelmayer, Daniel Havel, Michael Quante, Maximillian Reichert, Roland M. Schmid, Ihsan Ekin Demir, Helmut Friess, Moritz Wildgruber, Jens Siveke, Alexander Muckenhuber, Katja Steiger, Wilko Weichert, Isabel Rauscher, Matthias Eiber, Marcus R. Makowski, Rickmer F. Braren

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Imaging angiogenesis in atherosclerosis in large arteries with 68Ga-NODAGA-RGD PET/CT: relationship with clinical atherosclerotic cardiovascular disease

Matthieu Dietz, Christel H. Kamani, Emmanuel Deshayes, Vincent Dunet, Periklis Mitsakis, George Coukos, Marie Nicod Lalonde, Niklaus Schaefer, John O. Prior

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Visualizing cellularity and angiogenesis in newly-diagnosed glioblastoma with diffusion and perfusion MRI and FET-PET imaging

Friederike Liesche-Starnecker, Georg Prokop, Igor Yakushev, Christine Preibisch, Claire Delbridge, Hanno S. Meyer, Kaywan Aftahy, Melanie Barz, Bernhard Meyer, Claus Zimmer, Jürgen Schlegel, Benedikt Wiestler, Jens Gempt

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

A physiologically based pharmacokinetic (PBPK) model to describe organ distribution of 68Ga-DOTATATE in patients without neuroendocrine tumors

H. Siebinga, B. J. de Wit-van der Veen, J. H. Beijnen, M. P. M. Stokkel, T. P. C. Dorlo, A. D. R. Huitema, J. J. M. A. Hendrikx

01.12.2021 | Short communication | Ausgabe 1/2021 Open Access

Potential and pitfalls of 89Zr-immuno-PET to assess target status: 89Zr-trastuzumab as an example

Marc C. Huisman, C. Willemien Menke-van der Houven van Oordt, Josée M. Zijlstra, Otto S. Hoekstra, Ronald Boellaard, Guus A. M. S. van Dongen, Dhaval K. Shah, Yvonne W. S. Jauw

01.12.2021 | Commentary | Ausgabe 1/2021 Open Access

An abbreviated therapy-dosimetric equation for the companion diagnostic/therapeutic [64/67Cu]Cu-SARTATE

Eric Laffon, Henri de Clermont, Roger Marthan

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

PSMA-ligand uptake can serve as a novel biomarker in primary prostate cancer to predict outcome after radical prostatectomy

Hui Wang, Thomas Amiel, Christoph Würnschimmel, Thomas Langbein, Katja Steiger, Isabel Rauscher, Thomas Horn, Tobias Maurer, Wolfgang Weber, Hans-Juergen Wester, Karina Knorr, Matthias Eiber

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Investigation of spleen CXCR4 expression by [68Ga]Pentixafor PET in a cohort of 145 solid cancer patients

Richard Lewis, Stefan Habringer, Malte Kircher, Maike Hefter, Caroline Anna Peuker, Rudolf Werner, Valëza Ademaj-Kospiri, Alexander Gäble, Wolfgang Weber, Hans-Jürgen Wester, Andreas Buck, Peter Herhaus, Constantin Lapa, Ulrich Keller

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

[18F]FDG-PET/CT in prone compared to supine position for optimal axillary staging and treatment in clinically node-positive breast cancer patients with neoadjuvant systemic therapy

Ariane A. van Loevezijn, Marcel P. M. Stokkel, Maarten L. Donswijk, Erik D. van Werkhoven, Marieke E. M. van der Noordaa, Frederieke H. van Duijnhoven, Marie-Jeanne T. F. D. Vrancken Peeters

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Preselection of robust radiomic features does not improve outcome modelling in non-small cell lung cancer based on clinical routine FDG-PET imaging

Carol Oliveira, Florian Amstutz, Diem Vuong, Marta Bogowicz, Martin Hüllner, Robert Foerster, Lucas Basler, Christina Schröder, Eric I. Eboulet, Miklos Pless, Sandra Thierstein, Solange Peters, Sven Hillinger, Stephanie Tanadini-Lang, Matthias Guckenberger

01.12.2021 | Review | Ausgabe 1/2021 Open Access

Comparison of nuclear imaging techniques and volumetric imaging for the prediction of postoperative mortality and liver failure in patients undergoing localized liver-directed treatments: a systematic review

Caroline Espersen, Lise Borgwardt, Peter Nørgaard Larsen, Trine Borup Andersen, Louise Stenholt, Lars J. Petersen

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Thrombocytopenia after meta-iodobenzylguanidine (MIBG) therapy in neuroblastoma patients may be caused by selective MIBG uptake via the serotonin transporter located on megakaryocytes

Thomas Blom, Rutger Meinsma, Franca di Summa, Emile van den Akker, André B. P. van Kuilenburg, Marten Hansen, Godelieve A. M. Tytgat

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Sex correction improves the accuracy of clinical dopamine transporter imaging

Emma A. Honkanen, Tommi Noponen, Risto Hirvilammi, Kari Lindholm, Riitta Parkkola, Juho Joutsa, Andrea Varrone, Valtteri Kaasinen

01.12.2021 | Short communication | Ausgabe 1/2021 Open Access

Correlation of in vivo imaging to morphomolecular pathology in translational research: challenge accepted

Simone Ballke, Irina Heid, Carolin Mogler, Rickmer Braren, Markus Schwaiger, Wilko Weichert, Katja Steiger

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

A novel read methodology to evaluate the optimal dose of 68Ga-satoreotide trizoxetan as a PET imaging agent in patients with gastroenteropancreatic neuroendocrine tumours: a phase II clinical trial

Colin G. Miller, Henning Grønbæk, Irene Virgolini, Andreas Kjaer, Pierre Terve, Shadfar Bahri, Peter Iversen, Hanna Svirydenka, Thomas Rohban, Sandy McEwan

01.12.2021 | Guideline | Ausgabe 1/2021 Open Access

EANM recommendations based on systematic analysis of small animal radionuclide imaging in inflammatory musculoskeletal diseases

Erik H. J. G. Aarntzen, Edel Noriega-Álvarez, Vera Artiko, André H. Dias, Olivier Gheysens, Andor W. J. M. Glaudemans, Chiara Lauri, Giorgio Treglia, Tim van den Wyngaert, Fijs W. B. van Leeuwen, Samantha Y. A. Terry

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Quantitative SPECT/CT parameters of myocardial 99mTechnetium-3,3-diphosphono-1,2-propanodicarboxylic acid (DPD) uptake in suspected cardiac transthyretin amyloidosis

Simona Ben-Haim, A. Chicheportiche, E. Goshen, M. Arad, M. Smekhov, L. J. Menezes, P. M. Elliott, E. O’Mahoney, E. Stern, Bella Yuzefovich, J. B. Bomanji

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

The metabolic parameters based on volume in PET/CT are associated with clinicopathological N stage of colorectal cancer and can predict prognosis

Hidenori Kido, Shunsuke Kato, Kimihiko Funahashi, Kazutoshi Shibuya, Yousuke Sasaki, Yoshihisa Urita, Masaaki Hori, Sunao Mizumura

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

The effects of molar activity on [18F]FDOPA uptake in patients with neuroendocrine tumors

Gilles N. Stormezand, Romano S. B. H. Schreuder, Adrienne H. Brouwers, Riemer H. J. A. Slart, Philip H. Elsinga, Annemiek M. E. Walenkamp, R. A. J. O. Dierckx, Andor W. J. M. Glaudemans, Gert Luurtsema

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Assessment of early metabolic progression in melanoma patients under immunotherapy: an 18F-FDG PET/CT study

Christos Sachpekidis, Annette Kopp-Schneider, Jessica C. Hassel, Antonia Dimitrakopoulou-Strauss

01.12.2021 | Short communication | Ausgabe 1/2021 Open Access

Quantitative evaluation of interim positron emission tomography in peripheral T-cell lymphoma

Lars Kurch, Ulrich Dührsen, Andreas Hüttmann, Thomas W. Georgi, Osama Sabri, Regine Kluge, Dirk Hasenclever

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

CERMEP-IDB-MRXFDG: a database of 37 normal adult human brain [18F]FDG PET, T1 and FLAIR MRI, and CT images available for research

Inés Mérida, Julien Jung, Sandrine Bouvard, Didier Le Bars, Sophie Lancelot, Franck Lavenne, Caroline Bouillot, Jérôme Redouté, Alexander Hammers, Nicolas Costes

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

[123I]MIBG is a better early marker of anthracycline cardiotoxicity than [18F]FDG: a preclinical SPECT/CT and simultaneous PET/MR study

Alexandra Oudot, Alan Courteau, Mélanie Guillemin, Jean-Marc Vrigneaud, Paul Michael Walker, François Brunotte, Alexandre Cochet, Bertrand Collin

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Benefits and harms of implementing [18F]FDG-PET/CT for diagnosing recurrent breast cancer: a prospective clinical study

Marianne Vogsen, Jeanette Dupont Jensen, Oke Gerke, Anne Marie Bak Jylling, Jon Thor Asmussen, Ivar Yannick Christensen, Poul-Erik Braad, Peter Thye-Rønn, Katrine Lydolph Søe, Marianne Ewertz, Malene Grubbe Hildebrandt

01.12.2021 | Review | Ausgabe 1/2021 Open Access

Imaging modalities for diagnosis and monitoring of cancer cachexia

Jessie Han, Luke Harrison, Lisa Patzelt, Mingming Wu, Daniela Junker, Stephan Herzig, Mauricio Berriel Diaz, Dimitrios C. Karampinos

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

The effect of eating on the uptake of PSMA ligands in the salivary glands

V. Mohan, N. M. Bruin, J. B. van de Kamer, J.-J. Sonke, W. V. Vogel

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Lung shunt fraction calculation using 99mTc-MAA SPECT/CT imaging for 90Y microsphere selective internal radiation therapy of liver tumors

Mike F. Georgiou, Russ A. Kuker, Matthew T. Studenski, Preeti P. Ahlman, Megan Witte, Lorraine Portelance

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

In vivo quantitative assessment of therapeutic response to bortezomib therapy in disseminated animal models of multiple myeloma with [18F]FDG and [64Cu]Cu-LLP2A PET

Anchal Ghai, Nikki Fettig, Francesca Fontana, John DiPersio, Mike Rettig, Julie O. Neal, Samuel Achilefu, Kooresh I. Shoghi, Monica Shokeen

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Automated liver lesion detection in 68Ga DOTATATE PET/CT using a deep fully convolutional neural network

Jonathan Wehrend, Michael Silosky, Fuyong Xing, Bennett B. Chin

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Evaluation of intracellular processes in quinolinic acid-induced brain damage by imaging reactive oxygen species generation and mitochondrial complex I activity

Rie Hosoi, Yuka Fujii, Ohba Hiroyuki, Miho Shukuri, Shingo Nishiyama, Masakatsu Kanazawa, Kenichiro Todoroki, Yasushi Arano, Toshihiro Sakai, Hideo Tsukada, Osamu Inoue

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

The prognostic significance of [18F]FDG PET/CT in multiple myeloma according to novel interpretation criteria (IMPeTUs)

Christos Sachpekidis, Maximilian Merz, Marc-Steffen Raab, Uta Bertsch, Vivienn Weru, Annette Kopp-Schneider, Anna Jauch, Hartmut Goldschmidt, Antonia Dimitrakopoulou-Strauss

01.12.2021 | Correction | Ausgabe 1/2021 Open Access

Correction to: Biokinetics, dosimetry and radiation risk in infants after 99mTc-MAG3 scans

J. Soares Machado, J. Tran-Gia, S. Schlögl, A. K. Buck, M. Lassmann

01.12.2021 | Retraction Note | Ausgabe 1/2021 Open Access

Retraction Note to: Inter- and intraobserver agreement of the quantitative assessment of [99mTc]-labelled anti-programmed death-ligand 1 (PD-L1) SPECT/CT in non-small cell lung cancer

Daniel Johnathan Hughes, Gitasha Chand, Vicky Goh, Gary J. R. Cook

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Alteration of neuroinflammation detected by 18F-GE180 PET imaging in place-conditioned rats with morphine withdrawal

Junpeng Li, Da Shao, Donglang Jiang, Qi Huang, Yihui Guan, Bin Lai, Jun Zhao, Fengchun Hua, Fang Xie

01.12.2021 | Review | Ausgabe 1/2021 Open Access

Rationale for MYC imaging and targeting in pancreatic cancer

Günter Schneider, Matthias Wirth, Ulrich Keller, Dieter Saur

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Convolutional neural network-based automatic heart segmentation and quantitation in 123I-metaiodobenzylguanidine SPECT imaging

Shintaro Saito, Kenichi Nakajima, Lars Edenbrandt, Olof Enqvist, Johannes Ulén, Seigo Kinuya

01.12.2021 | Review | Ausgabe 1/2021 Open Access

There is a world beyond αvβ3-integrin: Multimeric ligands for imaging of the integrin subtypes αvβ6, αvβ8, αvβ3, and α5β1 by positron emission tomography

Katja Steiger, Neil Gerard Quigley, Tanja Groll, Frauke Richter, Maximilian Alexander Zierke, Ambros Johannes Beer, Wilko Weichert, Markus Schwaiger, Susanne Kossatz, Johannes Notni

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Short-duration dynamic [18F]DCFPyL PET and CT perfusion imaging to localize dominant intraprostatic lesions in prostate cancer: validation against digital histopathology and comparison to [18F]DCFPyL PET/MR at 120 minutes

Dae-Myoung Yang, Ryan Alfano, Glenn Bauman, Jonathan D. Thiessen, Joseph Chin, Stephen Pautler, Madeleine Moussa, Jose A. Gomez, Irina Rachinsky, Mena Gaed, Kevin J. Chung, Aaron Ward, Ting-Yim Lee

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Predicting the nature of pleural effusion in patients with lung adenocarcinoma based on 18F-FDG PET/CT

Yi Li, Wei Mu, Yuan Li, Xiao Song, Yan Huang, Lei Jiang

01.12.2021 | Original research | Ausgabe 1/2021 Open Access

Intraindividual comparison of [68 Ga]-Ga-PSMA-11 and [18F]-F-PSMA-1007 in prostate cancer patients: a retrospective single-center analysis

Sebastian Hoberück, Steffen Löck, Angelika Borkowetz, Ulrich Sommer, Robert Winzer, Klaus Zöphel, Dieter Fedders, Enrico Michler, Jörg Kotzerke, Klaus Kopka, Tobias Hölscher, Anja Braune

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