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Erschienen in:

06.08.2018 | REVIEW

Emerging roles of non-coding RNAs in the pathogenesis, diagnosis and prognosis of osteosarcoma

verfasst von: Chongchong Wang, Juehua Jing, Li Cheng

Erschienen in: Investigational New Drugs | Ausgabe 6/2018

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Summary

Non-coding RNAs (ncRNAs) have been found to play essential roles in various physiological and pathological processes. The involvement of ncRNAs in the development of osteosarcoma (OS) has been explored in recent years. In this review, we summarize the functions and mechanisms of microRNA, lncRNA and circRNA in the initiation and progression of OS. We specifically focused on their potential application in the diagnosis, prognosis and therapy of OS. This summary of current knowledge on the involvement of ncRNAs in OS will not only aid comprehension of the complex processes of OS initiation and progression but also contribute to the exploration of ideal diagnostic biomarkers and therapeutic targets for OS patients.
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Metadaten
Titel
Emerging roles of non-coding RNAs in the pathogenesis, diagnosis and prognosis of osteosarcoma
verfasst von
Chongchong Wang
Juehua Jing
Li Cheng
Publikationsdatum
06.08.2018
Verlag
Springer US
Erschienen in
Investigational New Drugs / Ausgabe 6/2018
Print ISSN: 0167-6997
Elektronische ISSN: 1573-0646
DOI
https://doi.org/10.1007/s10637-018-0624-7

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