Erschienen in:
01.12.2001 | Paper Report
Endocrine response: Is CGAthe key?
verfasst von:
Valerie Speirs
Erschienen in:
Breast Cancer Research
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Ausgabe 1/2000
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Excerpt
Oestrogen receptor (ER) is an established prognostic marker in breast cancer and expressed in about two thirds of all patients. The presence of ER is used routinely to predict response to adjuvant endocrine therapy. However, not all patients with ER-positive tumours respond, so there is a need to identify alternative markers of endocrine responsiveness. In this study, the authors evaluated the role of the CGA gene (coding for the a subunit of glycoprotein) as a novel ER-responsive gene in a cohort of human breast tumours. …