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Erschienen in: Langenbeck's Archives of Surgery 5/2007

01.09.2007 | Original Article

Endoscopic posterior mesorectal resection as an option to combine local treatment of early stage rectal cancer with partial mesorectal lymphadenectomy

verfasst von: Jörg Köninger, Beat P. Müller-Stich, Frank Autschbach, Peter Kienle, Jürgen Weitz, Markus W. Büchler, Carsten N. Gutt

Erschienen in: Langenbeck's Archives of Surgery | Ausgabe 5/2007

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Abstract

Background and aims

Low anterior resection and abdominoperineal resection with total mesorectal excision are the standard treatment in patients with low rectal cancer. Rectal resection remains a surgical intervention with considerable morbidity and long-term impairment of quality of life. Local excision of low rectal cancer is regarded as an alternative to radical surgery; however, occurrence of lymph node metastasis even in patients with highly differentiated early-stage rectal cancer may be underestimated.

Patients and results

In two patients with T1 rectal cancer, minimal-invasive partial excision of the mesorectum was performed after transanal excision of the tumor. The postoperative course was uneventful in both patients. Patients left the hospital on the fourth and fifth postoperative day without any complaints. In one patient, histo-pathological workup revealed a lymph node metastasis in the specimen.

Discussion

The technique of “Endoscopic posterior mesorectal resection” represents an interesting option in the surgical treatment of rectal cancer, as it allows for the first time an organ preserving resection of local lymph nodes in the small pelvis. It may evolve as an efficient new staging procedure to identify patients with metastatic disease who may benefit from multimodal treatment or extended surgery.
Literatur
1.
Zurück zum Zitat Andreola S, Leo E, Belli F, Bufalino R, Tomasic G, Lavarino C, Baldini MT, Meroni E (1996) Manual dissection of adenocarcinoma of the lower third of the rectum specimens for detection of lymph node metastases smaller than 5 mm. Cancer 77:607–612PubMedCrossRef Andreola S, Leo E, Belli F, Bufalino R, Tomasic G, Lavarino C, Baldini MT, Meroni E (1996) Manual dissection of adenocarcinoma of the lower third of the rectum specimens for detection of lymph node metastases smaller than 5 mm. Cancer 77:607–612PubMedCrossRef
2.
Zurück zum Zitat Beral DL, Monson JR (2005) Is local excision of T2/T3 rectal cancers adequate? Recent results. Cancer Res 165:120–135 Beral DL, Monson JR (2005) Is local excision of T2/T3 rectal cancers adequate? Recent results. Cancer Res 165:120–135
3.
Zurück zum Zitat Braat AE, Oosterhuis JW, Moll FC, de Vries JE, Wiggers T (2005) Sentinel node detection after preoperative short-course radiotherapy in rectal carcinoma is not reliable. Br J Surg 92:1533–1538PubMedCrossRef Braat AE, Oosterhuis JW, Moll FC, de Vries JE, Wiggers T (2005) Sentinel node detection after preoperative short-course radiotherapy in rectal carcinoma is not reliable. Br J Surg 92:1533–1538PubMedCrossRef
4.
Zurück zum Zitat Canessa CE, Badia F, Fierro S, Fiol V, Hayek G (2001) Anatomic study of the lymph nodes of the mesorectum. Dis Colon Rectum 44:1333–1336PubMedCrossRef Canessa CE, Badia F, Fierro S, Fiol V, Hayek G (2001) Anatomic study of the lymph nodes of the mesorectum. Dis Colon Rectum 44:1333–1336PubMedCrossRef
5.
Zurück zum Zitat Fisher SE, Daniels IR (2006) Quality of life and sexual function following surgery for rectal cancer. Colorectal Dis 8(Suppl 3):40–42PubMedCrossRef Fisher SE, Daniels IR (2006) Quality of life and sexual function following surgery for rectal cancer. Colorectal Dis 8(Suppl 3):40–42PubMedCrossRef
6.
Zurück zum Zitat Funahashi K, Koike J, Shimada M, Okamoto K, Goto T, Teramoto T (2006) A preliminary study of the draining lymph node basin in advanced lower rectal cancer using a radioactive tracer. Dis Colon Rectum 49:S53–S58PubMedCrossRef Funahashi K, Koike J, Shimada M, Okamoto K, Goto T, Teramoto T (2006) A preliminary study of the draining lymph node basin in advanced lower rectal cancer using a radioactive tracer. Dis Colon Rectum 49:S53–S58PubMedCrossRef
7.
Zurück zum Zitat Goldstein NS, Sanford W, Coffey M, Layfield LJ (1996) Lymph node recovery from colorectal resection specimens removed for adenocarcinoma. Trends over time and a recommendation for a minimum number of lymph nodes to be recovered. Am J Clin Pathol 106:209–216PubMed Goldstein NS, Sanford W, Coffey M, Layfield LJ (1996) Lymph node recovery from colorectal resection specimens removed for adenocarcinoma. Trends over time and a recommendation for a minimum number of lymph nodes to be recovered. Am J Clin Pathol 106:209–216PubMed
8.
Zurück zum Zitat Gopaul D, Belliveau P, Vuong T, Trudel J, Vasilevsky CA, Corns R, Gordon PH (2004) Outcome of local excision of rectal carcinoma. Dis Colon Rectum 47:1780–1788PubMedCrossRef Gopaul D, Belliveau P, Vuong T, Trudel J, Vasilevsky CA, Corns R, Gordon PH (2004) Outcome of local excision of rectal carcinoma. Dis Colon Rectum 47:1780–1788PubMedCrossRef
9.
Zurück zum Zitat Hladik P, Vizd’a J, Hadzi ND, Dvorak J, Voboril Z (2005) Radio-guided sentinel node detection during the surgical treatment of rectal cancer. Nucl Med Common 26:977–982CrossRef Hladik P, Vizd’a J, Hadzi ND, Dvorak J, Voboril Z (2005) Radio-guided sentinel node detection during the surgical treatment of rectal cancer. Nucl Med Common 26:977–982CrossRef
10.
Zurück zum Zitat Nascimbeni R, Burgart LJ, Nivatvongs S, Larson DR (2002) Risk of lymph node metastasis in T1 carcinoma of the colon and rectum. Dis Colon Rectum 45:200–206PubMedCrossRef Nascimbeni R, Burgart LJ, Nivatvongs S, Larson DR (2002) Risk of lymph node metastasis in T1 carcinoma of the colon and rectum. Dis Colon Rectum 45:200–206PubMedCrossRef
11.
Zurück zum Zitat Nascimbeni R, Nivatvongs S, Larson DR, Burgart LJ (2004) Long-term survival after local excision for T1 carcinoma of the rectum. Dis Colon Rectum 47:1773–1779PubMedCrossRef Nascimbeni R, Nivatvongs S, Larson DR, Burgart LJ (2004) Long-term survival after local excision for T1 carcinoma of the rectum. Dis Colon Rectum 47:1773–1779PubMedCrossRef
12.
Zurück zum Zitat O’Connell MJ, Martenson JA, Wieand HS, Krook JE, Macdonald JS, Haller DG, Mayer RJ, Gunderson LL, Rich TA (1994) Improving adjuvant therapy for rectal cancer by combining protracted-infusion fluorouracil with radiation therapy after curative surgery. N Engl J Med 331:502–507PubMedCrossRef O’Connell MJ, Martenson JA, Wieand HS, Krook JE, Macdonald JS, Haller DG, Mayer RJ, Gunderson LL, Rich TA (1994) Improving adjuvant therapy for rectal cancer by combining protracted-infusion fluorouracil with radiation therapy after curative surgery. N Engl J Med 331:502–507PubMedCrossRef
13.
Zurück zum Zitat Rothenberger DA, Garcia-Aguilar J (2000) Role of local excision in the treatment of rectal cancer. Semin Surg Oncol 19:367–375PubMedCrossRef Rothenberger DA, Garcia-Aguilar J (2000) Role of local excision in the treatment of rectal cancer. Semin Surg Oncol 19:367–375PubMedCrossRef
14.
Zurück zum Zitat Stelzner F, Ruhlmann J (2001) PET examinations of recurrent rectal carcinoma, 2. Chirurg 72:818–821PubMedCrossRef Stelzner F, Ruhlmann J (2001) PET examinations of recurrent rectal carcinoma, 2. Chirurg 72:818–821PubMedCrossRef
15.
Zurück zum Zitat Topor B, Acland R, Kolodko V, Galandiuk S (2003) Mesorectal lymph nodes: their location and distribution within the mesorectum. Dis Colon Rectum 46:779–785PubMedCrossRef Topor B, Acland R, Kolodko V, Galandiuk S (2003) Mesorectal lymph nodes: their location and distribution within the mesorectum. Dis Colon Rectum 46:779–785PubMedCrossRef
16.
Zurück zum Zitat Vorburger S, Metzger U (2000) Role of lymph nodes in rectal carcinoma. Zentralbl Chir 125:852–862PubMedCrossRef Vorburger S, Metzger U (2000) Role of lymph nodes in rectal carcinoma. Zentralbl Chir 125:852–862PubMedCrossRef
17.
Zurück zum Zitat Wagman RT, Minsky BD (2001) Conservative management of rectal cancer with local excision and adjuvant therapy. Oncology (Williston Park) 15:513–519, 524 Wagman RT, Minsky BD (2001) Conservative management of rectal cancer with local excision and adjuvant therapy. Oncology (Williston Park) 15:513–519, 524
18.
Zurück zum Zitat Weitz J, Koch M, Debus J, Hohler T, Galle PR, Buchler MW (2005) Colorectal cancer. Lancet 365:153–165PubMedCrossRef Weitz J, Koch M, Debus J, Hohler T, Galle PR, Buchler MW (2005) Colorectal cancer. Lancet 365:153–165PubMedCrossRef
19.
Zurück zum Zitat Zerz A, Beck J, Szinicz G (1999) Dorso-posterior extraperitoneal pelviscopy (DEP). From experiment to initial clinical application. Chirurg 70:294–297PubMedCrossRef Zerz A, Beck J, Szinicz G (1999) Dorso-posterior extraperitoneal pelviscopy (DEP). From experiment to initial clinical application. Chirurg 70:294–297PubMedCrossRef
20.
Zurück zum Zitat Zerz A, Muller-Stich BP, Beck J, Linke GR, Tarantino I, Lange J (2006) Endoscopic posterior mesorectal resection after transanal local excision of T1 carcinomas of the lower third of the rectum. Dis Colon Rectum 49:919–924PubMedCrossRef Zerz A, Muller-Stich BP, Beck J, Linke GR, Tarantino I, Lange J (2006) Endoscopic posterior mesorectal resection after transanal local excision of T1 carcinomas of the lower third of the rectum. Dis Colon Rectum 49:919–924PubMedCrossRef
Metadaten
Titel
Endoscopic posterior mesorectal resection as an option to combine local treatment of early stage rectal cancer with partial mesorectal lymphadenectomy
verfasst von
Jörg Köninger
Beat P. Müller-Stich
Frank Autschbach
Peter Kienle
Jürgen Weitz
Markus W. Büchler
Carsten N. Gutt
Publikationsdatum
01.09.2007
Verlag
Springer-Verlag
Erschienen in
Langenbeck's Archives of Surgery / Ausgabe 5/2007
Print ISSN: 1435-2443
Elektronische ISSN: 1435-2451
DOI
https://doi.org/10.1007/s00423-007-0211-4

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