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01.06.2015 | Ausgabe 6/2015

Surgical Endoscopy 6/2015

Endoscopic ultrasound: valuable tool for diagnosis of biliary complications in liver transplant recipients?

Zeitschrift:
Surgical Endoscopy > Ausgabe 6/2015
Autoren:
Anna Hüsing, Vito R. Cicinnati, Susanne Beckebaum, Christian Wilms, Hartmut H. Schmidt, Iyad Kabar

Abstract

Background

Biliary complications after liver transplantation (LT) are still common and are an important cause of mortality and morbidity. Until now, endoscopic retrograde cholangiopancreatography (ERCP) has been considered the gold standard for diagnosing such complications. The aim of this study was to evaluate the diagnostic yield and therapeutic impact of endoscopic ultrasound (EUS) in the management of biliary complications after LT.

Methods

Thirty-seven liver transplant patients who presented with clinical, biochemical, sonographic, and/or histological evidence of biliary complications, and who first received EUS followed by ERCP, were enrolled into this prospective observational study. Subsequently, we evaluated the value of EUS in detecting and classifying biliary complications after LT.

Results

Thirty-seven biliary complications were detected in 32 patients. Endoscopic ultrasound showed an overall sensitivity and accuracy of 94.6 % each. In cases of biliary cast and ischemic cholangiopathy, EUS was found to be diagnostically superior to ERCP and has had, in these cases, a significant impact on clinical decision-making. However, EUS was less reliable when diagnosing anastomotic strictures.

Conclusion

EUS can complement ERCP to improve diagnosis of biliary complications after LT and help guide treatment strategies to address these complications.

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