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Clinical Reviews in Allergy & Immunology

Erschienen in:

30.12.2017

Eosinophilic Esophagitis Clinical Manifestations and Differential Diagnosis

verfasst von: Diana Muñoz-Mendoza, Adrián Chapa-Rodríguez, Sami L. Bahna

Erschienen in: Clinical Reviews in Allergy & Immunology | Ausgabe 1/2018

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Abstract

As a chronic inflammatory disease with eosinophilic infiltrate of the esophagus, eosinophilic esophagitis (EoE) causes a variety of gastrointestinal (GI) clinical manifestations. None of the symptoms, endoscopic features, or biopsy findings is pathognomonic of the disease, even with high degrees of esophageal eosinophilia. The pathogenesis has been explored by several studies, yet it still far from being completely understood. Evidence supports a role of allergen-driven Th2 lymphocyte mechanism, though not in every patient. This article addresses the disease’s clinical manifestations, endoscopic findings, diagnosis, and differential diagnoses. In addition to the current diagnostic criteria, we summarize some recently emerging procedures that promise of enhancing more precise diagnosis and institution of early appropriate management, with consequent better quality of life and reduction of complications.

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Titel: Eosinophilic Esophagitis Clinical Manifestations and Differential Diagnosis
verfasst von: Diana Muñoz-Mendoza
Adrián Chapa-Rodríguez
Sami L. Bahna
Publikationsdatum: 30.12.2017
Verlag: Springer US
Erschienen in: Clinical Reviews in Allergy & Immunology / Ausgabe 1/2018
Print ISSN: 1080-0549
Elektronische ISSN: 1559-0267
DOI: https://doi.org/10.1007/s12016-017-8663-y

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Eosinophilic Esophagitis Clinical Manifestations and Differential Diagnosis

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