Erschienen in:
01.06.2005 | Oral Presentation
ERβ in normal and malignant breast
verfasst von:
J-Å Gustafsson, G Cheng, M Warner
Erschienen in:
Breast Cancer Research
|
Sonderheft 2/2005
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Excerpt
Both ERα and ERβ are expressed in not only normal breast of the rodent, cow, monkey and human, but also in breast cancer. Cells that express ERα are found within the luminal epithelium, but not in the myoepithelium or stroma in the human breast. ERβ, on the other hand, is expressed not only in the luminal epithelial cells, but also in myoepithelial cells, stromal cells and in passenger lymphocytes. This widespread distribution of ERβ suggests multiple roles for ERβ in the mammary gland. …