Erratum
During the editorial process preceding the publication of this article an error was introduced in the heading of “Table 1 Univariate and multivariate analysis of elafin-positive cells in breast cancer patients.” This error was only noticed after publication of the final version. Specifically, both data-containing columns are labeled “Elafin Negative.” The data-containing column on the right should in fact be labeled “Elafin Positive (n = 482).” The corrected version can be found here (Table 1). Table 1 has also been updated in the original article to reflect the correct labeling of the columns.
Table 1
Univariate and multivariate analysis of elafin-positive cells in breast cancer patients
A. Univariate analysis, breast cancer (n = 793)
| ||||
|---|---|---|---|---|
Factors
|
Elafin negative (n = 311)
|
Elafin positive (n = 482)
|
p-value
| |
Age of diagnosis, year
| 0.02 | |||
Mean | 55.5 | 53.5 | ||
Median (range) | 55 (26–86) | 52 (25–87) | ||
Stage
| <0.0001 | |||
I | 120 (38.7) | 115 (24.0) | ||
IIA | 128 (41.3) | 241 (50.2) | ||
IIB | 62 (20.0) | 124 (25.8) | ||
Unknown | 1 | 2 | ||
ER
| <0.0001 | |||
Positive | 266 (85.5) | 280 (58.3) | ||
Negative | 45 (14.5) | 200 (41.7) | ||
Unknown | 0 | 2 | ||
PR
| <0.0001 | |||
Positive | 218 (70.1) | 236 (49.2) | ||
Negative | 93 (29.9) | 244 (50.8) | ||
Unknown | 0 | 2 | ||
HER-2
| 0.013 | |||
Positive | 42 (13.5) | 98 (20.4) | ||
Negative | 269 (86.5) | 383 (79.6) | ||
Unknown | 0 | 1 | ||
Grade
| <0.0001 | |||
I | 41 (14.2) | 31 (6.8) | ||
II | 186 (64.6) | 197 (43.5) | ||
III | 61 (21.2) | 225 (49.7) | ||
Unknown | 23 | 29 | ||
Tumor subtype
| <0.0001 | |||
Luminal A | 185 (61.9) | 158 (33.1) | ||
Luminal B | 45 (15.1) | 94 (19.8) | ||
Her2 positive | 42 (14.0) | 98 (20.7) | ||
Triple negative | 27 (9.0) | 125 (26.4) | ||
Unknown | 12 | 7 | ||
Recurrence
| <0.0001 | |||
No | 250 (80.9) | 298 (62.3) | ||
Yes | 59 (19.1) | 180 (37.7) | ||
Unknown | 2 | 4 | ||
B. Multivariate Cox proportional hazards analysis of clinicopathologic variables’ influence on breast cancer RFS in whole cohort (n = 793)
| ||||
Factor
|
HR
|
Se
|
P
|
95% CI
|
Stage
| ||||
I | referent | |||
IIA | 1.67 | 0.31 | 0.005 | 1.17-2.39 |
IIB | 2.41 | 0.47 | <0.0001 | 1.65-3.52 |
Age
| 0.98 | 0.01 | <0.0001 | 0.97-0.99 |
Elafin Positive
| 1.94 | 0.3 | <0.0001 | 1.44-2.62 |