Acknowledgements
We thank Christien Gabriel and Dawn Roberts for technical support. This study was funded by a Tenovus PhD scholarship (LP), seed-corn funding from the Breast Cancer Campaign (RC) and additional part-funding from CR-UK (ME) and BBSRC (NO). RC and ME are RC-UK Research Fellows.
Competing interests
The authors declare that they have no competing interests.
Authors’ contributions
LP was responsible for the design of the experiments, assembly of data and manuscript writing. NO was responsible for the design of experiments, data collection and manuscript writing. SMP developed a new assay. RF was responsible for the design and execution of experiments for one of the figures. ME handled data analysis and interpretation, funding of research and manuscript writing. RC was responsible for the conception and design of the study, data analysis and interpretation, manuscript writing, final approval of manuscript and funding of research. All authors have read and approved the manuscript for publication.