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Rheumatology International

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02.03.2017 | Cases with a Message

Etanercept-induced leukemia: could increased mean corpuscular volume be a predictor of hematologic malignancy?

verfasst von: Döndü Üsküdar Cansu, Hava Üsküdar Teke, Cengiz Korkmaz

Erschienen in: Rheumatology International | Ausgabe 8/2017

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Abstract

In rheumatology practice, anti-tumor necrosis factor (TNF) alpha agents are frequently used medications, more so in ankylosing spondylitis (AS). There are case reports, besides their adverse effects, such as infection and injection site reaction, suggesting these agents may cause solid or hematologic malignancies. Acute leukemia secondary to anti-TNF alpha agents has been rarely reported in patients with AS. In this case report, based on a patient who developed acute leukemia while on the treatment with etanercept, we will discuss whether it is possible to predict acute leukemia by monitoring the mean corpuscular volume in light of the literature.

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Titel: Etanercept-induced leukemia: could increased mean corpuscular volume be a predictor of hematologic malignancy?
verfasst von: Döndü Üsküdar Cansu
Hava Üsküdar Teke
Cengiz Korkmaz
Publikationsdatum: 02.03.2017
Verlag: Springer Berlin Heidelberg
Erschienen in: Rheumatology International / Ausgabe 8/2017
Print ISSN: 0172-8172
Elektronische ISSN: 1437-160X
DOI: https://doi.org/10.1007/s00296-017-3687-4

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Etanercept-induced leukemia: could increased mean corpuscular volume be a predictor of hematologic malignancy?

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