Ausgabe 3/2025
Inhalt (40 Artikel)
A cutting-edge technology for the future of nuclear medicine
- Editorial
Andor W.J.M. Glaudemans, Adriaan A. Lammertsma, Simon R. Cherry, Paola A. Erba, Axel Rominger, Rudi A.J.O. Dierckx, Ronald Boellaard, Alexander Hammers, Rodney J. Hicks, Riemer H.J.A. Slart
Identifying and navigating bottlenecks in the translation of novel radiopharmaceuticals: a perspective
- Open Access
- Editorial
Margret Schottelius
Editorial Commentary: Should “heterogeneous response” be considered as new category for assessing treatment response in patients with breast cancer?
- Editorial
Sofia C. Vaz, David Groheux, Thiemo van Nijnatten, Lidija Antunovic, Fatima Cardoso, Felix Mottaghy, Maria Joao Cardoso, Christopher Riedl, Lioe-Fee de Geus-Oei, Gary A. Ulaner
Letter to the Editor: EANM position paper on challenges and opportunities of full-ring 360° CZT bone imaging: it’s time to let go of planar whole-body bone imaging
- Letter to the Editor
Paulo Schiavom Duarte
This union must happen: Radiomics and LAFOV PET/CT as the power couple of nuclear medicine
- Letter to the Editor
Luca Filippi, Francesco Bianconi, Orazio Schillaci, Barbara Palumbo
Persistent dysfunctions of brain metabolic connectivity in long-covid with cognitive symptoms
- Original Article
Anna Lisa Martini, Giulia Carli, Silvia Paola Caminiti, Lorenzo Kiferle, Andrea Leo, Daniela Perani, Stelvio Sestini
Identification of metabolic progression and subtypes in progressive supranuclear palsy by PET molecular imaging
- Original Article
Haotian Wang, Bo Wang, Yi Liao, Jiaqi Niu, Miao Chen, Xinhui Chen, Xiaofeng Dou, Congcong Yu, Yan Zhong, Jing Wang, Nan Jin, Yixin Kang, Hong Zhang, Mei Tian, Wei Luo
Individual-level metabolic connectivity from dynamic [18F]FDG PET reveals glioma-induced impairments in brain architecture and offers novel insights beyond the SUVR clinical standard
- Original Article
Giulia Vallini, Erica Silvestri, Tommaso Volpi, John J. Lee, Andrei G. Vlassenko, Manu S. Goyal, Diego Cecchin, Maurizio Corbetta, Alessandra Bertoldo
Dopaminergic PET to SPECT domain adaptation: a cycle GAN translation approach
- Open Access
- Original Article
Leonor Lopes, Fangyang Jiao, Song Xue, Thomas Pyka, Korbinian Krieger, Jingjie Ge, Qian Xu, Rachid Fahmi, Bruce Spottiswoode, Ahmed Soliman, Ralph Buchert, Matthias Brendel, Jimin Hong, Yihui Guan, Claudio L. A. Bassetti, Axel Rominger, Chuantao Zuo, Kuangyu Shi, Ping Wu
Synthesis, preclinical assessment, and first-in-human study of [18F]d4-FET for brain tumor imaging
- Original Article
Lu Hou, Zhiyong Chen, Fanfan Chen, Lianghe Sheng, Weijian Ye, Yingchu Dai, Xiaoyu Guo, Chenchen Dong, Guocong Li, Kai Liao, Yinlong Li, Jie Ma, Huiyi Wei, Wenqing Ran, Jingjie Shang, Xueying Ling, Jimmy S. Patel, Steven H. Liang, Hao Xu, Lu Wang
EANM perspective on clinical PET and SPECT imaging in schizophrenia-spectrum disorders: a systematic review of longitudinal studies
- Open Access
- Review Article
Antoine Rogeau, Anne Jetske Boer, Eric Guedj, Arianna Sala, Iris E. Sommer, Mattia Veronese, Monique van der Weijden-Germann, Donatienne Van Weehaeghe, Diego Cecchin, Antoine Verger, Nathalie L. Albert, Matthias Brendel, Igor Yakushev, Tatjana Traub-Weidinger, Henryk Barthel, Nelleke Tolboom, Francesco Fraioli
PET/CT imaging of differentiated and medullary thyroid carcinoma using the novel SSTR-targeting peptide [18F]SiTATE – first clinical experiences
- Open Access
- Original Article
Sophie C. Kunte, Vera Wenter, Johannes Toms, Simon Lindner, Marcus Unterrainer, Friederike Eilsberger, Klaus Jurkschat, Carmen Wängler, Björn Wängler, Ralf Schirrmacher, Maximilian W. Tiling, Gabriel T. Sheikh, Dirk Mehrens, Matthias Brendel, Johannes Rübenthaler, Christoph J. Auernhammer, Christine Spitzweg, Lena M. Unterrainer, Adrien Holzgreve
Using a novel PSMA-PET and PSA-based model to enhance the diagnostic accuracy for clinically significant prostate cancer and avoid unnecessary biopsy in men with PI-RADS ≤ 3 MRI
- Original Article
Yujia Li, Jian Li, Jinhui Yang, Ling Xiao, Ming Zhou, Yi Cai, Axel Rominger, Kuangyu Shi, Robert Seifert, Xiaomei Gao, Yongxiang Tang, Shuo Hu
First-in-human study of dosimetry, safety and efficacy for [177Lu]Lu-P15-073: a novel bisphosphonate-based radioligand therapy (RLT) agent for bone metastases
- Original Article
Ruiyue Zhao, Jie Lv, Mingzhao Li, Siran Xu, Wenhua Liang, Xinqing Lin, Di Gu, Guohua Zeng, Wenbin Jin, Qingsong Yan, Huizhen Zhong, David Alexoff, Karl Ploessl, Lin Zhu, Hank F. Kung, Xinlu Wang
Assessment of the therapeutic efficacy of [177Lu]Lu-PSMA-X compared to taxane chemotherapy in taxane-chemo-naïve patients with metastatic castration-resistant prostate cancer: A systematic review and meta-analysis
- Original Article
Ludmila Santiago Almeida, Irene García Megías, Elba Cristina Sá Camargo Etchebehere, Adriana K. Calapaquí Terán, Ken Herrmann, Francesco Giammarile, Giorgio Treglia, Roberto C. Delgado Bolton
Nuclear imaging of PD-L1 expression promotes the synergistic antitumor efficacy of targeted radionuclide therapy and immune checkpoint blockade
- Original Article
Jiyun Shi, Hannan Gao, Yue Wu, Chuangwei Luo, Guangjie Yang, Qi Luo, Bing Jia, Chuanhui Han, Zhaofei Liu, Fan Wang
Experience of rescue therapy with [177Lu]Lu-rhPSMA-10.1 in patients with primary or acquired resistance to [177Lu]Lu-PSMA-I&T
- Open Access
- Original Article
Alexander Gäble, Alexander Dierks, Andreas Rinscheid, Marianne Patt, Georgine Wienand, Christian H. Pfob, Malte Kircher, Kazuhito Fukushima, Ana Antić Nikolić, Johanna S. Enke, Tilman Janzen, Julie Steinestel, Hildegard Kempter, Martin Trepel, Dorothea Weckermann, Constantin Lapa, Ralph A. Bundschuh
A head-to-head comparison of [68Ga]Ga-DOTA-FGFR1 and [18F]FDG PET/CT in the diagnosis of lung cancer
- Original Article
Huiqing Yuan, Xiaoshan Chen, Xinming Zhao, Meng Dai, Yunuan Liu, Jingya Han, Fenglian Jing, Xiaolin Chen, Xiao Pang, Zhaoqi Zhang, Jingmian Zhang, Jianfang Wang, Mengjiao Wang
Holmium-166 radioembolisation dosimetry in HCC
- Open Access
- Original Article
Margot T. M. Reinders, Arthur J. A. T. Braat, Karel J. van Erpecum, Joep de Bruijne, Rutger C. G. Bruijnen, Dave Sprengers, Rob de Man, Erik Vegt, Jan N. M. IJzermans, Sjoerd G. Elias, Marnix G. E. H. Lam, Maarten L. J. Smits
Long-axial field-of-view PET/CT improves radiomics feature reliability
- Original Article
Ian L. Alberts, Song Xue, Hasan Sari, Lara Cavinato, George Prenosil, Ali Afshar-Oromieh, Clemens Mingels, Kuangyu Shi, Federico Caobelli, Arman Rahmim, Thomas Pyka, Axel Rominger
Preoperative assessment of pancreatic cancer with [68Ga]Ga-DOTA-FAPI-04 PET/MR versus [18F]-FDG PET/CT plus contrast-enhanced CT: a prospective preliminary study
- Original Article
Zeyu Zhang, Shiwei Guo, Weiwei Su, Guixia Pan, Kai Cao, Hui Jiang, Lu Zhang, Chao Cheng, Gang Jin, Changjing Zuo
Smaller is better? Compact vs. Conventional gamma camera for sentinel lymph node localization in patients with breast cancer
- Original Article
Alexandra Lazar, Fabrizia Gelardi, Andrea Sagona, Marcello Rodari, Lorenzo Leonardi, Roberto Massari, Annunziata D’Elia, Andrea Soluri, Arturo Chiti, Lidija Antunovic
Expert consensus on workflow of PET/CT with long axial field-of-view
- Guidelines
Guobing Liu, Yushen Gu, Martina Sollini, Alexandra Lazar, Florent L. Besson, Sijin Li, Zhifang Wu, Lorenzo Nardo, Akram Al-Ibraheem, Jiefu Zheng, Harshad R. Kulkarni, Axel Rominger, Wei Fan, Xiaohua Zhu, Xinming Zhao, Hubing Wu, Jianjun Liu, Biao Li, Zhaoping Cheng, Ruimin Wang, Baixuan Xu, Denis Agostini, Han Tang, Lijie Tan, Zhi Yang, Li Huo, Jianying Gu, Hongcheng Shi
Coronary artery calcium measurement on attenuation correction computed tomography using artificial intelligence: correlation with coronary flow capacity and prognosis
- Open Access
- Original Article
Sang-Geon Cho, Jong Eun Lee, Kyung Hoon Cho, Ki-Seong Park, Jahae Kim, Jang Bae Moon, Kang Bin Kim, Ju Han Kim, Ho-Chun Song
Remote ischemic periconditioning suppresses cardiac sympathetic activation in acute myocardial infarction: a randomized controlled trial
- Original Article
Takumi Kondo, Masahiro Seo, Tetsuya Watanabe, Takahisa Yamada, Takashi Morita, Masato Kawasaki, Atsushi Kikuchi, Tsutomu Kawai, Yuji Nishimoto, Jun Nakamura, Takeshi Fujita, Masanao Tanichi, Yongchol Chang, Yasushi Sakata, Masatake Fukunami
Clinical significance of quantitative assessment of right ventricular amyloid burden with [99mTc]Tc-DPD SPECT/CT in transthyretin cardiac amyloidosis
- Original Article
Min Zhao, Raffaella Calabretta, Patrick Binder, Josef Yu, Zewen Jiang, Christian Nitsche, Philipp Bartko, René Rettl, Tim Wollenweber, Katharina Mascherbauer, Diana Bondermann, Marcus Hacker, Xiang Li
Comparison of [18F]FAPI-42 and [18F]FDG PET/CT in the evaluation of systemic vasculitis
- Original Article
Kaixiang Zhong, Haiming Chen, Peng Hou, Linling Cheng, Wenliang Guo, Youcai Li, Jie Lv, Miao Ke, Xiaofeng Wu, Yongxia Lei, Chunli Liu, Cheng Hong, Xinlu Wang
Hybrid cardiovascular imaging. A clinical consensus statement of the european association of nuclear medicine (EANM) and the european association of cardiovascular imaging (EACVI) of the ESC
- Open Access
- Guidelines
Federico Caobelli, Marc R. Dweck, Domenico Albano, Olivier Gheysens, Panagiotis Georgoulias, Stephan Nekolla, Olivier Lairez, Lucia Leccisotti, Marc Lubberink, Samia Massalha, Carmela Nappi, Christoph Rischpler, Antti Saraste, Fabien Hyafil
Enhancing the tissue penetration to improve sonodynamic immunotherapy for pancreatic ductal adenocarcinoma using membrane-camouflaged nanoplatform
- Original Article
Jiawei Du, Xin Chen, Xiaoxuan Xu, Ziting Que, Mengyan Zhai, Qinyanqiu Xiang, Zhiwei Zhang, Zhiqi Zhang, Yong Shao, Xue Yang, Fengqin Miao, Jianqiong Zhang, Jinbing Xie, Shenghong Ju
Evaluation of a targeted anti-αvβ3 integrin near-infrared fluorescent dye for fluorescence-guided resection of naturally occurring soft tissue sarcomas in dogs
- Open Access
- Original Article
Patricia Beer, Paula Grest, Christiane Krudewig, Chris Staudinger, Stefanie Ohlerth, Carla Rohrer Bley, Armin Jarosch, Houria Ech-Cherif, Enni Markkanen, Brian Park, Mirja Christine Nolff
Tumor agnostic ultrasmall nanoprobes for fluorescence-guided surgical resection in peritoneal metastasis
- Original Article
Neetu Singh, Wenxi Xia, Esther Need, Kylee McManus, Jiemin Huang, Sixiang Shi, Shreya Goel
Design, preclinical evaluation, and first-in-human PET study of [68Ga]Ga-PSFA-01: a PSMA/FAP heterobivalent tracer
- Original Article
Xinlin Wang, Xiaoyang Zhang, Xiaojun Zhang, Lili Guan, Xi Gao, Lu Xu, Hua Pang, Jin Du, Jinming Zhang, Mengchao Cui
Towards the clinical translation of a silver sulfide nanoparticle contrast agent: large scale production with a highly parallelized microfluidic chip
- Open Access
- Original Article
Katherine J. Mossburg, Sarah J. Shepherd, Diego Barragan, Nathaniel H. O, Emily K. Berkow, Portia S. N. Maidment, Derick N. Rosario Berrios, Jessica C. Hsu, Michael J. Siedlik, Sagar Yadavali, Michael J. Mitchell, David Issadore, David P. Cormode
Synthesis and preclinical evaluation of [18F]AlF-NOTA-Asp2-PEG2-JR11 as a novel antagonist radioligand for PET imaging of somatostatin receptor
- Original Article
Haoran Liang, Zihao Chen, Chunwei Mo, Yanjiang Han, Qingxing Liu, Ganghua Tang
EANM position paper on challenges and opportunities of full-ring 360° CZT bone imaging: it’s time to let go of planar whole-body bone imaging
- Open Access
- Review Article
Richard Graham, David Morland, Sarah Cade, Laetitia Imbert, Emmanouil Panagiotidis, Jens Kurth, Frédéric Paycha, Tim Van den Wyngaert
EANM expert opinion: How can lessons from radiobiology be applied to the design of clinical trials? Part I: back to the basics of absorbed dose–response and threshold absorbed doses
- Open Access
- Review Article
Jean-Pierre Pouget, Pablo Minguez Gabina, Ken Herrmann, Desirée Deandreis, Mark Konijnenberg, David Taieb, Fijs W. B. van Leeuwen, Jens Kurth, Uta Eberlein, Michael Lassmann, Katharina Lückerath
Enhanced differentiation of uveal melanoma and benign sinonasal lesion using [18F]AlF-NOTA-PRGD2 PET/CT
- Image of the Month
Ling Wang, Xue Zhu, Jing Fang, Zhihong Huang, Yan Xue, Shuang Wang, Ke Wang
Positive amyloid and tau PET in an early-onset Alzheimer’s disease with a rare PSEN1 (Arg278Gly) mutation
- Image of the Month
Liu Yang, Ping Dong, Li Li, Lin Li, Minggang Su
Long axial field-of-view PET imaging of intraarterial 2-[18F]FDG injection
- Open Access
- Image of the Month
Korbinian Krieger, Carola Maria Bregenzer, Luis Weissenrieder, Axel Rominger, Thomas Pyka
Intense [68Ga]Ga-FAPI-04 uptake of pancreatic microcystic serous cystadenoma mimicking malignancy
- Image of the Month
Tuo Ma, Xiaoqian Zhao, Weiwei Tian, Nuo Li, Jingmian Zhang, Xinming Zhao
