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Erschienen in: Surgical Endoscopy 1/2021

21.09.2020 | New Technology

EUS-guided fine needle tattooing (EUS-FNT) for preoperative localization of small pancreatic neuroendocrine tumors (p-NETs): a single-center experience

verfasst von: Fausto Rosa, Mihai Rimbaș, Gianenrico Rizzatti, Giuseppe Quero, Claudio Fiorillo, Michele Impagnatiello, Francesca D’Aversa, Guido Costamagna, Sergio Alfieri, Alberto Larghi

Erschienen in: Surgical Endoscopy | Ausgabe 1/2021

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Abstract

Background

and study aims
Pancreatic neuroendocrine tumors (pNETs) can be difficult to detect intra-operatively. The aim of this paper is to evaluate the safety and efficacy of preoperative endoscopic ultrasound guided fine needle tattooing (EUS-FNT) to facilitate intra-operative detection of pNETs.

Patients and methods

Sixteen patients with pNETs (8 insulinoma and 8 non-functional pancreatic neuroendocrine tumors) underwent EUS-FNT. The procedure was carried out using the conventional curvilinear EUS. Tattooing was performed by intralesional injection of 1–2 mL of Spot® ink (Spot®, GI Supply, Comp Hill, PA, US) using a standard 22 gauge EUS-FNA needle.

Results

All identified pNETs could be tattooed in one session. The procedure was well tolerated in all patients without any complication. The time interval between tattooing and surgery was between 1 and 565 days (mean of 52 days). Nine patients underwent open and seven laparoscopic surgery. The tattooed lesions could be recognized in all but one patient. In one patient, a small hematoma secondary to the EUS-FNT was observed. Pathological examination of the resection specimen showed local R0 resection in all cases, and no interference with the specimen evaluation was encountered.

Conclusions

Our results suggest that EUS-guided FNT is a safe and useful method to mark preoperatively small (≤ 2 cm) pNETs.
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Metadaten
Titel
EUS-guided fine needle tattooing (EUS-FNT) for preoperative localization of small pancreatic neuroendocrine tumors (p-NETs): a single-center experience
verfasst von
Fausto Rosa
Mihai Rimbaș
Gianenrico Rizzatti
Giuseppe Quero
Claudio Fiorillo
Michele Impagnatiello
Francesca D’Aversa
Guido Costamagna
Sergio Alfieri
Alberto Larghi
Publikationsdatum
21.09.2020
Verlag
Springer US
Erschienen in
Surgical Endoscopy / Ausgabe 1/2021
Print ISSN: 0930-2794
Elektronische ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-020-07996-5

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