Skip to main content
main-content

14.03.2016 | Original Paper | Ausgabe 1/2017

International Ophthalmology 1/2017

Evaluating the presence of Toxoplasma gondii in peripheral blood of patients with diverse forms of uveitis

Zeitschrift:
International Ophthalmology > Ausgabe 1/2017
Autoren:
Rubens N. Belfort, Jordan Isenberg, Bruno F. Fernandes, Sebastian Di Cesare, Rubens Belfort Jr., Miguel N. Burnier Jr.
Wichtige Hinweise
Partial results presented at the ARVO 2008/9, Fort Lauderdale, FL USA and the World Ophthalmology Congress 2008, Hong Kong, SAR-PRC. This work was funded in part by a grant from Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (Brazil).

Abstract

The purpose of this study was to evaluate the presence of Toxoplasmosis gondii in samples of peripheral blood from patients with varying etiologies of uveitis. Whole blood from patients with different forms of uveitis was tested for the presence of T. gondii using real-time PCR targeting the well-characterized 529 bp fragment. Extracted DNA was both frozen. Thirty-one patients were included in the current study and grouped as follows: acute toxoplasmosis (n = 10); toxoplasmic retinal scars (n = 9); non-infectious etiologies of uveitis (n = 6); and IgG negative for toxoplasmosis (n = 6). In total, only two patients were shown to have circulating T. gondii in peripheral blood; both of these patients were IgG positive for toxoplasmosis, were receiving immunosuppressive therapy for autoimmune uveitis, and had no clinical features of toxoplasmosis. T. gondii was identified in peripheral blood of some immunosuppressed patients. No other patients, including those with acute toxoplasmosis, had circulating parasites in peripheral blood.

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

★ PREMIUM-INHALT
e.Med Interdisziplinär

Für Ihren Erfolg in Klinik und Praxis - Die beste Hilfe in Ihrem Arbeitsalltag als Mediziner

Mit e.Med Interdisziplinär erhalten Sie Zugang zu allen CME-Fortbildungen und Fachzeitschriften auf SpringerMedizin.de.

Jetzt e.Med zum Sonderpreis bestellen!

Literatur
Über diesen Artikel

Weitere Artikel der Ausgabe 1/2017

International Ophthalmology 1/2017 Zur Ausgabe

Neu im Fachgebiet Augenheilkunde

28.08.2020 | Leitthema | Ausgabe 10/2020

Künstliche Intelligenz in der Augenheilkunde

Leitfaden für Ärzte zur kritischen Bewertung von Studien