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Erschienen in: Abdominal Radiology 10/2017

04.05.2017

Evaluation of biliary ductal anatomy in potential living liver donors: comparison between MRCP and Gd-EOB-DTPA-enhanced MRI

verfasst von: D. Santosh, A. Goel, I. W. Birchall, A. Kumar, K. H. Lee, V. H. Patel, G. Low

Erschienen in: Abdominal Radiology | Ausgabe 10/2017

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Abstract

Purpose

To compare magnetic resonance cholangiopancreatography (MRCP) and Gd-EOB-DTPA-enhanced MRI in the evaluation of the biliary anatomy in potential living liver donors (LLDs).

Methods

A retrospective study was conducted in a tertiary care liver transplant center after obtaining ethics and institutional approvals. A total of 42 potential LLD MRI examinations were performed between November 2013 and March 2016. All patients underwent a standard MRI protocol which included MRCP and Gd-EOB-DTPA-enhanced MRI sequences in a single session. Three abdominal MR radiologists independently reviewed the studies and completed a customized data collection sheet for each MR sequence. The readers subjectively scored the bile duct visualization on each MR sequence on a Likert scale and classified the biliary anatomic configuration. Statistical analysis was performed using intraclass correlation coefficient and the McNemar Chi-square (χ 2) test.

Results

The 42 potential LLDs included 22 males and 20 females with an age range of 18–60 years. There was ‘good’ or ‘excellent’ inter-reader agreement on either MRI examination for the visualization of the first- and second-order ducts and the majority of third-order ducts. ‘Good’ inter-reader agreement on Gd-EOB-DTPA-enhanced MRI and ‘fair’ inter-reader agreement on MRCP was noted for the left third-order medial duct. There was significantly better visualization of the cystic duct, left hepatic duct, and right second-order ducts on Gd-EOB-DTPA-enhanced MRI compared with MRCP. A 12.6% improvement in classifying the biliary branch pattern was also observed on Gd-EOB-DTPA-enhanced MRI compared with MRCP (P = 0.03).

Conclusion

Gd-EOB-DTPA-enhanced MRI provides additional diagnostic confidence over MRCP in the evaluation of the biliary ductal anatomy in potential LLDs.
Literatur
2.
Zurück zum Zitat Lee VS, Morgan GR, Teperman LW, et al. (2001) MR imaging as the sole preoperative imaging modality for right hepatectomy: a prospective study of living adult-to-adult liver donor candidates. AJR Am J Roentgenol 176(6):1475–1482CrossRefPubMed Lee VS, Morgan GR, Teperman LW, et al. (2001) MR imaging as the sole preoperative imaging modality for right hepatectomy: a prospective study of living adult-to-adult liver donor candidates. AJR Am J Roentgenol 176(6):1475–1482CrossRefPubMed
3.
Zurück zum Zitat Kinner S, Steinweg V, Maderwald S, et al. (2014) Bile duct evaluation of potential living liver donors with Gd-EOB-DTPA enhanced MR cholangiography: single-dose, double dose or half-dose contrast enhanced imaging. Eur J Radiol 83(5):763–767CrossRefPubMed Kinner S, Steinweg V, Maderwald S, et al. (2014) Bile duct evaluation of potential living liver donors with Gd-EOB-DTPA enhanced MR cholangiography: single-dose, double dose or half-dose contrast enhanced imaging. Eur J Radiol 83(5):763–767CrossRefPubMed
4.
Zurück zum Zitat Kim WR, Stock PG, Smith JM, et al. (2013) OPTN/SRTR 2011 annual data report: liver. Am J Transplant 13(1):73–102CrossRefPubMed Kim WR, Stock PG, Smith JM, et al. (2013) OPTN/SRTR 2011 annual data report: liver. Am J Transplant 13(1):73–102CrossRefPubMed
6.
Zurück zum Zitat Xu X, Wei X, Ling Q, et al. (2012) Inaccurate preoperative imaging assessment on biliary anatomy not increases biliary complications after living donor liver transplantation. Eur J Radiol 81(4):e457–e460CrossRefPubMed Xu X, Wei X, Ling Q, et al. (2012) Inaccurate preoperative imaging assessment on biliary anatomy not increases biliary complications after living donor liver transplantation. Eur J Radiol 81(4):e457–e460CrossRefPubMed
7.
Zurück zum Zitat Catalano OA, Singh AH, Uppot RN, et al. (2008) Vascular and biliary variants in the liver: implications for liver surgery. Radiographics 28(2):359–378CrossRefPubMed Catalano OA, Singh AH, Uppot RN, et al. (2008) Vascular and biliary variants in the liver: implications for liver surgery. Radiographics 28(2):359–378CrossRefPubMed
8.
Zurück zum Zitat Mangold S, Bretschneider C, Fenchel M, et al. (2012) MRI for evaluation of potential living liver donors: a new approach including contrast-enhanced magnetic resonance cholangiography. Abdominal imaging. 37(2):244–251CrossRefPubMed Mangold S, Bretschneider C, Fenchel M, et al. (2012) MRI for evaluation of potential living liver donors: a new approach including contrast-enhanced magnetic resonance cholangiography. Abdominal imaging. 37(2):244–251CrossRefPubMed
9.
Zurück zum Zitat Tsang LL, Chen CL, Huang TL, et al. (2008) Preoperative imaging evaluation of potential living liver donors: reasons for exclusion from donation in adult living donor liver transplantation. Transplant Proc 40(8):2460–2462CrossRefPubMed Tsang LL, Chen CL, Huang TL, et al. (2008) Preoperative imaging evaluation of potential living liver donors: reasons for exclusion from donation in adult living donor liver transplantation. Transplant Proc 40(8):2460–2462CrossRefPubMed
10.
Zurück zum Zitat Lee NK, Kim S, Lee JW, et al. (2009) Biliary MR imaging with Gd-EOB-DTPA and its clinical applications. Radiographics 29(6):1707–1724CrossRefPubMed Lee NK, Kim S, Lee JW, et al. (2009) Biliary MR imaging with Gd-EOB-DTPA and its clinical applications. Radiographics 29(6):1707–1724CrossRefPubMed
11.
Zurück zum Zitat Hyodo T, Kumano S, Kushihata F, et al. (1015) CT and MR cholangiography: advantages and pitfalls in perioperative evaluation of biliary tree. Br J Radiol 2012(85):887–896 Hyodo T, Kumano S, Kushihata F, et al. (1015) CT and MR cholangiography: advantages and pitfalls in perioperative evaluation of biliary tree. Br J Radiol 2012(85):887–896
12.
Zurück zum Zitat Limanond P, Raman SS, Ghobrial RM, Busuttil RW, Lu DS (2004) The utility of MRCP in preoperative mapping of biliary anatomy in adult-to-adult living related liver transplant donors. J Magn Reson Imaging 19(2):209–215CrossRefPubMed Limanond P, Raman SS, Ghobrial RM, Busuttil RW, Lu DS (2004) The utility of MRCP in preoperative mapping of biliary anatomy in adult-to-adult living related liver transplant donors. J Magn Reson Imaging 19(2):209–215CrossRefPubMed
13.
Zurück zum Zitat Van Beers BE, Pastor CM, Hussain HK (2012) Primovist, Eovist: what to expect? J Hepatol 57(2):421–429CrossRefPubMed Van Beers BE, Pastor CM, Hussain HK (2012) Primovist, Eovist: what to expect? J Hepatol 57(2):421–429CrossRefPubMed
14.
Zurück zum Zitat Ringe KI, Husarik DB, Sirlin CB, Merkle EM (2010) Gadoxetate disodium-enhanced MRI of the liver: part 1, protocol optimization and lesion appearance in the noncirrhotic liver. AJR Am J Roentgenol 195(1):13–28CrossRefPubMed Ringe KI, Husarik DB, Sirlin CB, Merkle EM (2010) Gadoxetate disodium-enhanced MRI of the liver: part 1, protocol optimization and lesion appearance in the noncirrhotic liver. AJR Am J Roentgenol 195(1):13–28CrossRefPubMed
15.
Zurück zum Zitat Melamud K, LeBedis CA, Anderson SW, Soto JA (2014) Biliary imaging: multimodality approach to imaging of biliary injuries and their complications. Radiographics 34(3):613–623CrossRefPubMed Melamud K, LeBedis CA, Anderson SW, Soto JA (2014) Biliary imaging: multimodality approach to imaging of biliary injuries and their complications. Radiographics 34(3):613–623CrossRefPubMed
16.
Zurück zum Zitat Choi JW, Kim TK, Kim KW, et al. (2003) Anatomic variation in intrahepatic bile ducts: an analysis of intraoperative cholangiograms in 300 consecutive donors for living donor liver transplantation. Korean J Radiol 4(2):85–90CrossRefPubMedPubMedCentral Choi JW, Kim TK, Kim KW, et al. (2003) Anatomic variation in intrahepatic bile ducts: an analysis of intraoperative cholangiograms in 300 consecutive donors for living donor liver transplantation. Korean J Radiol 4(2):85–90CrossRefPubMedPubMedCentral
17.
Zurück zum Zitat Cicchetti DV (1994) Guidelines, criteria, and rules of thumb for evaluating normed and standardized assessment instruments in psychology. Psychol Assess. 6(4):284–290CrossRef Cicchetti DV (1994) Guidelines, criteria, and rules of thumb for evaluating normed and standardized assessment instruments in psychology. Psychol Assess. 6(4):284–290CrossRef
18.
Zurück zum Zitat Girometti R, Baccarani U (2013) Magnetic resonance cholangiopancreatography in assessing living liver donors biliary anatomy: opportunities and challenges. Hepat Surg Nutr 2(3):165–167 Girometti R, Baccarani U (2013) Magnetic resonance cholangiopancreatography in assessing living liver donors biliary anatomy: opportunities and challenges. Hepat Surg Nutr 2(3):165–167
19.
20.
Zurück zum Zitat Gazelle GS, Lee MJ, Mueller PR (1994) Cholangiographic segmental anatomy of the liver. Radiographics 14(5):1005–1013CrossRefPubMed Gazelle GS, Lee MJ, Mueller PR (1994) Cholangiographic segmental anatomy of the liver. Radiographics 14(5):1005–1013CrossRefPubMed
21.
Zurück zum Zitat Puente SG, Bannura GC (1983) Radiological anatomy of the biliary tract: variations and congenital abnormalities. World J Surg 7(2):271–276CrossRefPubMed Puente SG, Bannura GC (1983) Radiological anatomy of the biliary tract: variations and congenital abnormalities. World J Surg 7(2):271–276CrossRefPubMed
23.
Zurück zum Zitat Willinek WA, Schild HH (2008) Clinical advantages of 3.0 T MRI over 1.5 T. Eur J Radiol 65(1):2–14CrossRefPubMed Willinek WA, Schild HH (2008) Clinical advantages of 3.0 T MRI over 1.5 T. Eur J Radiol 65(1):2–14CrossRefPubMed
24.
Zurück zum Zitat Mo YH, Liang PC, Ho MC, et al. (2009) Morphine- and glucagon-augmented magnetic resonance cholangiopancreatography to evaluate living liver donors. Liver Transplant 15(9):1021–1027CrossRef Mo YH, Liang PC, Ho MC, et al. (2009) Morphine- and glucagon-augmented magnetic resonance cholangiopancreatography to evaluate living liver donors. Liver Transplant 15(9):1021–1027CrossRef
Metadaten
Titel
Evaluation of biliary ductal anatomy in potential living liver donors: comparison between MRCP and Gd-EOB-DTPA-enhanced MRI
verfasst von
D. Santosh
A. Goel
I. W. Birchall
A. Kumar
K. H. Lee
V. H. Patel
G. Low
Publikationsdatum
04.05.2017
Verlag
Springer US
Erschienen in
Abdominal Radiology / Ausgabe 10/2017
Print ISSN: 2366-004X
Elektronische ISSN: 2366-0058
DOI
https://doi.org/10.1007/s00261-017-1157-9

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