Erschienen in:
04.05.2017
Evaluation of biliary ductal anatomy in potential living liver donors: comparison between MRCP and Gd-EOB-DTPA-enhanced MRI
verfasst von:
D. Santosh, A. Goel, I. W. Birchall, A. Kumar, K. H. Lee, V. H. Patel, G. Low
Erschienen in:
Abdominal Radiology
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Ausgabe 10/2017
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Abstract
Purpose
To compare magnetic resonance cholangiopancreatography (MRCP) and Gd-EOB-DTPA-enhanced MRI in the evaluation of the biliary anatomy in potential living liver donors (LLDs).
Methods
A retrospective study was conducted in a tertiary care liver transplant center after obtaining ethics and institutional approvals. A total of 42 potential LLD MRI examinations were performed between November 2013 and March 2016. All patients underwent a standard MRI protocol which included MRCP and Gd-EOB-DTPA-enhanced MRI sequences in a single session. Three abdominal MR radiologists independently reviewed the studies and completed a customized data collection sheet for each MR sequence. The readers subjectively scored the bile duct visualization on each MR sequence on a Likert scale and classified the biliary anatomic configuration. Statistical analysis was performed using intraclass correlation coefficient and the McNemar Chi-square (χ
2) test.
Results
The 42 potential LLDs included 22 males and 20 females with an age range of 18–60 years. There was ‘good’ or ‘excellent’ inter-reader agreement on either MRI examination for the visualization of the first- and second-order ducts and the majority of third-order ducts. ‘Good’ inter-reader agreement on Gd-EOB-DTPA-enhanced MRI and ‘fair’ inter-reader agreement on MRCP was noted for the left third-order medial duct. There was significantly better visualization of the cystic duct, left hepatic duct, and right second-order ducts on Gd-EOB-DTPA-enhanced MRI compared with MRCP. A 12.6% improvement in classifying the biliary branch pattern was also observed on Gd-EOB-DTPA-enhanced MRI compared with MRCP (P = 0.03).
Conclusion
Gd-EOB-DTPA-enhanced MRI provides additional diagnostic confidence over MRCP in the evaluation of the biliary ductal anatomy in potential LLDs.