Evaluation of clinical, hematological, and biochemical changes following autologous blood transfusion in goats

Blood transfusion is an important remedy to manage animals with severe anemia. The risk of pathogen transmission can be reduced using autologous blood transfusion. Due to the lack of studies related to the use of autologous blood transfusions in goats, this study was conducted to evaluate the clinical, hematological, and biochemical changes following blood collection and reinfusion in goats. Fifteen milliliters per kilogram of whole blood was collected and reinfused after 7 days. The heart rate and respiratory rate were increased following blood collection and decreased to normal values within 48 and 6 h, respectively (p < 0.05). The hematocrit and red blood cells were increased significantly (p < 0.05) following blood reinfusion and decreased 48 h thereafter. White blood cells were increased 3 h after blood reinfusion and decreased within 96 h (p < 0.05). With respect to biochemical parameters, the total protein was increased significantly (p < 0.05) following blood reinfusion and decreased 96 h thereafter. Urea and creatinine were increased 3 h after blood collection and decreased within 24 h (p < 0.05). In conclusion, slight changes in clinical, hematological, and biochemical parameters indicated that the autologous blood transfusion technique proposed in this study was safe and could be used in clinical practices in goats.