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Erschienen in: Medical Oncology 3/2012

01.09.2012 | Review Article

Evaluation of molecular prognostic and predictive factors: an important step towards personalised treatment in non small cell lung cancer

verfasst von: Alfredo Tartarone, Rose Lerose, Giuseppina Gallucci, Raffaele Ardito, Michele Aieta

Erschienen in: Medical Oncology | Ausgabe 3/2012

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Abstract

Treatment for patients with advanced NSCLC generally consists of chemotherapy, but response rates are modest and recurrence occurs for most patients after standard first-line platinum-based doublet therapy. Tailoring therapy to individual patient according to certain prognostic and predictive factors has the potential to improve outcome in NSCLC. This review focuses on the most important molecular prognostic and/or predictive factors in the treatment of advanced NSCLC; considering these molecular features, we also suggest a molecular-based treatment algorithm.
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Metadaten
Titel
Evaluation of molecular prognostic and predictive factors: an important step towards personalised treatment in non small cell lung cancer
verfasst von
Alfredo Tartarone
Rose Lerose
Giuseppina Gallucci
Raffaele Ardito
Michele Aieta
Publikationsdatum
01.09.2012
Verlag
Springer US
Erschienen in
Medical Oncology / Ausgabe 3/2012
Print ISSN: 1357-0560
Elektronische ISSN: 1559-131X
DOI
https://doi.org/10.1007/s12032-011-9992-y

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