Evaluation of plasma fibrinogen levels in type 2 diabetes mellitus

The aim of the study was to assess the plasma fibrinogen levels in type 2 diabetes mellitus patients and to compare with that of healthy controls. To correlate plasma fibrinogen levels with blood pressure (BP), BMI (Body Mass Index) and HbA1c (Glycated hemoglobin) among diabetics and healthy controls. Blood samples were collected for Plasma fibrinogen levels and HbA1c from 30 diagnosed type 2 diabetes mellitus patients. Their BP and BMI were recorded. 30 age and sex matched healthy subjects were included as a control group. There was a rise in plasma fibrinogen levels in diabetics with BMI < 25 kg/m² as compared to controls of the same BMI group (P = 0.097). Also, there was a trend of raised plasma fibrinogen levels among male diabetics as compared to male control subjects (P = 0.079). However, there appears no such difference among female individuals. However, there was no significant correlation between fibrinogen levels, blood pressure and HbA1c both among controls and diabetic cases (P >0.05). Though there was a slight trend of increasing levels of plasma fibrinogen among diabetics as compared to controls. However, a significant positive correlation between BMI, male gender and increasing age with plasma fibrinogen was found.