nach oben

Zeitschrift für Rheumatologie

Erschienen in:

12.11.2018 | Originalien

Evaluation of restless legs syndrome and sleep disorders in patients with psoriatic arthritis

verfasst von: S. C. Sandikci, MD, S. Colak, R. Aydoğan Baykara, A. Öktem, E. Cüre, A. Omma, A. Kucuk

Erschienen in: Zeitschrift für Rheumatologie | Ausgabe 10/2019

Einloggen, um Zugang zu erhalten

Abstract

Objectives

Restless legs syndrome (RLS) is a neurological disease with a chronic course that is characterised by sleep disorders and sensorimotor impairment. The aim of this study was to evaluate the prevalence and severity of RLS in psoriatic arthritis (PSA) patients and those with psoriasis (P).

Patients and methods

The study included 50 patients with psoriasis (28 females, 22 males), 50 PSA patients (33 females, 17 males) and 50 healthy control subjects (34 females, 16 males), and all 3 groups were matched with respect to age, gender and body mass index (BMI). Evaluations were made using the International RLS Rating Scale, Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale, Insomnia Severity Index, Fatigue Severity Scale (FSS), Beck Depression Index (BDI) and the SF-36 quality of life scores.

Results

RLS was determined at a higher rate in the PSA patients (64.0%), compared to the P group (20.0%, p < 0.001) and the control group (14.0%, p < 0.001). The number of moderate and severe RLS cases was significantly higher in the PSA group (68.7%) compared to the P group (30%, p < 0.001) and the control group (0%, p < 0.001). In regression analysis, an independent correlation was found between the RLS score and PSQI (beta [β] = 0.269, p = 0.002), FSS (β = 0.243, p = 0.003), SF-36 physical score (β = 0.242, p = 0.004) and BDI (β = 0.177, p = 0.036).

Conclusion

RLS was determined in PSA patients at a higher rate than in psoriasis patients. The presence of RLS in PSA and psoriasis patients is related to impairments in sleep and quality of life, fatigue and depression.

Parisi R, Symmons DP, Griffiths CE et al (2013) Identification and Management of Psoriasis and Associated ComorbidiTy (IMPACT) project team. Globalepidemiology of psoriasis: a systematic review of incidence and prevalence. J Invest Dermatol 133:377–385PubMed

Albanesi C, Madonna S, Gisondi P et al (2018) The interplay between keratinocytes and immune cells in the pathogenesis of psoriasis. Front Immunol 9:1549PubMedPubMedCentral

Pap T, Sunderkötter C (2017) Psoriasis vs. psoriatic arthritis: similarities and differences in the pathophysiology. Z Rheumatol 76:477–483PubMed

Liu JT, Yeh HM, Liu SY et al (2014) Psoriatic arthritis: epidemiology, diagnosis, and treatment. World J Orthop 5:537–543PubMedPubMedCentral

Coates LC, Helliwell PS (2010) Disease measurement—enthesitis, skin, nails, spine and dactylitis. Best Pract Res Clin Rheumatol 24:659–670PubMed

Busse K, Liao W (2010) Which psoriasis patients develop psoriatic arthritis? Psoriasis Forum 16:17–25PubMedPubMedCentral

Ogdie A, Gelfand JM (2015) Clinical risk factors for the development of psoriatic arthritis among patients with psoriasis: a review of available evidence. Curr Rheumatol Rep 17:64PubMedPubMedCentral

Garcia-Borreguero D, Cano-Pumarega I (2017) New concepts in the management of restless legs syndrome. BMJ 356:j104PubMed

Manconi M, Ulfberg J, Berger K et al (2012) When gender matters: restless legs syndrome. Report of the “RLS and woman” workshop endorsed by the European RLS Study Group. Sleep Med Rev 16:297–307PubMed

10.

Bogan RK, Cheray JA (2013) Restless legs syndrome: a review of diagnosis and management in primary care. Postgrad Med 125:99–111PubMed

11.

Mucsi I, Molnar MZ, Ambrus C et al (2005) Restless legs syndrome, insomnia and quality of life in patients on maintenance dialysis. Nephrol Dial Transplant 20:571–577PubMed

12.

Giannaki CD, Hadjigavriel M, Lazarou A et al (2017) Restless legs syndrome is contributing to fatigue and low quality of life levels in hemodialysis patients. World J Nephrol 6:236–242PubMedPubMedCentral

13.

Schell C, Schleich R, Walker F et al (2015) Restless legs syndrome in psoriasis: an unexpected comorbidity. Eur J Dermatol 25:255–260PubMed

14.

Temel AB, Karaman NS, Bozkurt S et al (2016) Prevalence of restless legs syndrome among psoriasis patients and association with depression and sleep quality. Turk J Dermatol 10:110–115

15.

Kucuk A, Uslu AU, Yilmaz R et al (2017) Relationship between prevalence and severity of restless legs syndrome and anemia in patients with systemic lupus erythematosus. Int J Rheum Dis 20:469–473PubMed

16.

Gupta MA, Simpson FC, Gupta AK (2016) Psoriasis and sleep disorders: a systematic review. Sleep Med Rev 29:63–75PubMed

17.

Gezer O, Batmaz I, Sariyildiz MA et al (2017) Sleep quality in patients with psoriatic arthritis. Int J Rheum Dis 20:1212–1218PubMed

18.

Duffin KC, Wong B, Krueger G (2009) Sleep disturbance and medical comorbidities in patients with psoriasis, psoriatic arthritis, and controls. J Am Acad Dermatol 1:AB9

19.

Taylor W, Gladman D, Helliwell P et al (2006) Classification criteria for psoriatic arthritis: development of new criteria from a large international study. Arthritis Rheum 54:2665–2673PubMed

20.

Allen RP, Picchietti D, Hening WA et al (2003) Restless legs syndrome: diagnostic criteria, special considerations, and epidemiology. A report from the restless legs syndrome diagnosis and epidemiology workshop at the national institutes of health. Sleep Med 4:101–119PubMed

21.

Walters AS, LeBrocq C, Dhar A et al (2003) Validation of the international restless legs syndrome study group rating scale for restless legs syndrome. Sleep Med 4:121–132PubMed

22.

Ware JE Jr, Sherbourne CD (1992) The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med Care 30:473–483PubMed

23.

Beck AT, Ward CH, Mehdelson M et al (1961) An inventory for measuring depresssion. Arch Gen Psychiatry 4:561–571PubMed

24.

Johns MWA (1991) New method for measuring daytime sleepiness: the Epworth sleepiness scale. Sleep 14:540–545PubMed

25.

Buysse DJ, Reynolds CF, Monk TH et al (1991) Quantification of subjective sleep quality in healthy elderly men and women using the Pittsburgh Sleep Quality Index (PSQI). Sleep 14:331–338PubMed

26.

Bastien CH, Vallières A, Morin CM (2001) Validation of the Insomnia Severity Index as an outcome measure for insomnia research. Sleep Med 2:297–307PubMed

27.

Valko PO, Bassetti CL, Bloch KE et al (2008) Validation of the fatigue severity scale in a Swiss cohort. Sleep 31:1601–1607PubMedPubMedCentral

28.

Jiménez-Jiménez FJ, Alonso-Navarro H, García-Martín E et al (2018) Genetics of restless legs syndrome: An update. Sleep Med Rev 39:108–121PubMed

29.

Ferré S, García-Borreguero D, Allen RP et al (2018) New insights into the neurobiology of restless legs syndrome. Neuroscientist. https://doi.org/10.1177/1073858418791763 CrossRefPubMed

30.

Guo S, Huang J, Jiang H et al (2017) Restless legs syndrome: from pathophysiology to clinical diagnosis and management. Front Aging Neurosci 9:171PubMedPubMedCentral

31.

Weinstock LB, Walters AS, Paueksakon P (2012) Restless legs syndrome—theoretical roles of inflammatory and immune mechanisms. Sleep Med Rev 16:341–354PubMed

32.

Taylor-Gjevre RM, Gjevre JA, Nair BV (2014) Increased nocturnal periodic limb movements in rheumatoid arthritis patients meeting questionnaire diagnostic criteria for restless legs syndrome. BMC Musculoskelet Disord 18(15):378

33.

Gjevre JA, Taylor Gjevre RM (2013) Restless legs syndrome as a comorbidity in rheumatoid arthritis. Autoimmune Dis 2013:352782PubMedPubMedCentral

34.

Ishaq M, Muhammad JS, Hameed K (2013) Risk of restless legs syndrome in low socioeconomic rheumatoid arthritis patients. Mod Rheumatol 23:705–708PubMed

35.

Ediz L, Hiz O, Toprak M et al (2011) Restless legs syndrome in Behçet’s disease. J Int Med Res 39:759–765PubMed

36.

Tekatas A, Pamuk ON (2015) Increased frequency of restless leg syndrome in patients with ankylosing spondylitis. Int J Rheum Dis 18:58–62PubMed

37.

Feld J, Chandran V, Haroon N (2018) Axial disease in psoriatic arthritis and ankylosing spondylitis: a critical comparison. Nat Rev Rheumatol 14:363–371PubMed

38.

Ferreira BR, Pio-Abreu JL, Reis JP et al (2017) Analysis of the prevalence of mental disorders in psoriasis: the relevance of psychiatric assessment in dermatology. Psychiatr Danub 29:401–406PubMed

39.

Cicek D, Halisdemir N, Dertioglu SB et al (2012) Increased frequency of restless legs syndrome in atopic dermatitis. Clin Exp Dermatol 37:469–476PubMed

40.

Winkelman JW, Redline S, Baldwin CM et al (2009) Polysomnographic and health-related quality of life correlates of restless legs syndrome in the Sleep Heart Health Study. Sleep 32:772–778PubMedPubMedCentral

41.

Wong ITY, Chandran V, Li S et al (2017) Sleep disturbance in psoriatic disease: prevalence and associated factors. J Rheumatol 44:1369–1374PubMed

42.

Henry AL, Kyle SD, Chisholm A et al (2017) A cross-sectional survey of the nature and correlates of sleep disturbance in people with psoriasis. Br J Dermatol 177:1052–1059PubMed

43.

Henry AL, Kyle SD, Bhandari S et al (2016) Measurement, classification and evaluation of sleep disturbance in psoriasis: a systematic review. PLoS ONE 11:e157843PubMedPubMedCentral

44.

Callis Duffin K, Wong B, Horn EJ et al (2009) Psoriatic arthritis is a strong predictor of sleep interference in patients with psoriasis. J Am Acad Dermatol 60:604–608PubMed

45.

Güler S, Tekatas A, Arican O et al (2015) Restless legs syndrome and insomnia frequency in patients with psoriasıs. Ideggyogy Sz 68:331–336PubMed

46.

Akdag Uzun Z, Kurt S, Karaer Unaldi H (2018) The relationship with restless legs syndrome, fibromyalgia, and depressive symptoms in migraine patients. Neurol Sci 39:1409–1414PubMed

Titel: Evaluation of restless legs syndrome and sleep disorders in patients with psoriatic arthritis
verfasst von: S. C. Sandikci, MD
S. Colak
R. Aydoğan Baykara
A. Öktem
E. Cüre
A. Omma
A. Kucuk
Publikationsdatum: 12.11.2018
Verlag: Springer Medizin
Erschienen in: Zeitschrift für Rheumatologie / Ausgabe 10/2019
Print ISSN: 0340-1855
Elektronische ISSN: 1435-1250
DOI: https://doi.org/10.1007/s00393-018-0562-y

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

^{Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag}

Kostenlos registrieren

Neu im Fachgebiet Innere Medizin

24.04.2024 | DGIM 2024 | Kongressbericht | Nachrichten

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen

Springer Medizin

Evaluation of restless legs syndrome and sleep disorders in patients with psoriatic arthritis

Abstract

Objectives

Patients and methods

Results

Conclusion

Leitlinien kompakt für die Innere Medizin

Neu im Fachgebiet Innere Medizin

Metformin rückt in den Hintergrund

Myokarditis nach Infekt – richtig schwierig wird es bei Profisportlern

Thrombophiliescreening – Wenn, dann richtig und nur bei therapeutischer Konsequenz

Bei Senioren mit Prostatakarzinom auf Anämie achten!

Update Innere Medizin

Springer Medizin

Abstract

Objectives

Patients and methods

Results

Conclusion

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 10/2019

Patienten mit rheumatischer Erkrankung auf der Intensivstation

Mitteilungen der DGRh

Therapie von Infektionen bei kritisch Kranken unter Immunsuppression

Was sind die Indikationen für Rescue-Verfahren?

Macrophage depletion with clodronate-containing liposomes affects the incidence and development of rheumatoid arthritis

Raynaud-Phänomen

Leitlinien kompakt für die Innere Medizin

Neu im Fachgebiet Innere Medizin

Metformin rückt in den Hintergrund

Myokarditis nach Infekt – richtig schwierig wird es bei Profisportlern

Thrombophiliescreening – Wenn, dann richtig und nur bei therapeutischer Konsequenz

Bei Senioren mit Prostatakarzinom auf Anämie achten!

Update Innere Medizin