Skip to main content
Hauptrubriken
CME Facharzt-Training Webinare Zeitschriften Bücher e.Medpedia Podcast
Service
Jobbörse Info & Hilfe
Fachgebiete
Anästhesiologie Allgemeinmedizin Arbeitsmedizin Augenheilkunde Chirurgie Dermatologie Gynäkologie und Geburtshilfe HNO Innere Medizin Kardiologie Neurologie Onkologie und Hämatologie Orthopädie und Unfallchirurgie Pädiatrie Pathologie Psychiatrie Radiologie Rechtsmedizin Urologie Zahnmedizin
Themen
Klimawandel und Gesundheit Neues aus dem Markt COVID-19 Praxis und Beruf Seltene Erkrankungen GOÄ & EBM Panorama
Sammlungen
Kasuistiken Algorithmen & Infografiken Blickdiagnosen Arthropedia FlapFinder (für Dermatochirurgen) Videos Kongressberichterstattung Medizin für Apothekerinnen und Apotheker Für Ärztinnen und Ärzte in Weiterbildung Für Medizinstudierende

Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Konkret geht es um den Diabetes-Patienten mit kardiovaskulären Erkrankungen oder Risiken, die Herzinsuffizienz sowie die kardiovaskuläre Primär- und Sekundärprävention. Sind Sie hier schon auf dem neuesten Stand? Unsere Experten beleuchten, wo und warum das bisherige Procedere geändert werden soll und was in der Praxis sinnvoll ist. Holen Sie sich Ihr Update und 2 CME-Punkte beim MMW-Webinar am 24. April von 17.30 bis 19 Uhr. 
Erweiterte Suche
Anmelden
nach oben
European Journal of Applied Physiology
Erschienen in: European Journal of Applied Physiology 5/2018

13.02.2018 | Invited Review

Exercise-induced fatigue in young people: advances and future perspectives

verfasst von: Dimitrios A. Patikas, Craig A. Williams, Sébastien Ratel

Erschienen in: European Journal of Applied Physiology | Ausgabe 5/2018

Einloggen, um Zugang zu erhalten

Abstract

Purpose

In recent decades, the interest for exercise-induced fatigue in youth has substantially increased, and the effects of growth on the peripheral (muscular) and central (neural) mechanisms underpinning differences in neuromuscular fatigue between healthy children and adults have been described more extensively. The purpose of this review is to retrieve, report, and analyse the findings of studies comparing neuromuscular fatigue between children and adults. Objective measures of the evaluation of the physiological mechanisms are discussed.

Method

Major databases (PubMed, Ovid, Scopus and Web of Science) were systematically searched and limited to English language from inception to September 2017.

Result

Collectively, the analyzed studies indicate that children experience less muscular and potentially more neural fatigue than adults. However, there are still many unknown aspects of fatigue regarding neural (supraspinal and spinal) and peripheral mechanisms that should be more thoroughly examined in children.

Conclusion

Suitable methods, such as transcranial magnetic stimulation, transcranial electrical stimulation, functional magnetic resonance imaging, near-infrared spectroscopy, tendon vibration, H-reflex, and ultrasound are recommended in the research field of fatigue in youth. By designing studies that test the fatigue effects in movements that replicate daily activities, new knowledge will be acquired. The linkage and interaction between physiological, cognitive, and psychological aspects of human performance remain to be resolved in young people. This can only be successful if research is based on a foundation of basic research focused on the mechanisms of fatigue while measuring all three above aspects.
Literatur
Allen DG, Lamb GD, Westerblad H (2008) Skeletal muscle fatigue: cellular mechanisms. Physiol Rev 88:287–332PubMedCrossRef
Amann M, Dempsey JA (2008) The concept of peripheral locomotor muscle fatigue as a regulated variable. J Physiol 7:2029–2030CrossRef
Amann M, Blain GM, Proctor LT, Sebranek JJ, Pegelow DF, Dempsey JA (2011) Implications of group III and IV muscle afferents for high-intensity endurance exercise performance in humans. J Physiol 589:5299–5309PubMedPubMedCentralCrossRef
Armatas V, Bassa E, Patikas D, Kitsas I, Zangelidis G, Kotzamanidis C (2010) Neuromuscular differences between men and prepubescent boys during a peak isometric knee extension intermittent fatigue test. Pediatr Exerc Sci 22:205–217PubMedCrossRef
Asmussen E (1979) Muscle fatigue. Med Sci Sports 11:313–321PubMed
Belanger AY, McComas AJ (1989) Contractile properties of human skeletal muscle in childhood and adolescence. Eur J Appl Physiol 58:563–567CrossRef
Berg A, Keul J (1988) Biochemical changes during exercise in children. In: Malina RM (ed) Young athletes/biological, psychological and educational perspectives. Human Kinetics, Champaign, pp 61–77
Bigland-Ritchie BR, Furbush FH, Woods JJ (1986) Fatigue of intermittent submaximal voluntary contractions: central and peripheral factors. J Appl Physiol 61:421–429PubMedCrossRef
Bottaro M, Brown LE, Celes R, Martorelli S, Carregaro R, de Brito Vidal JC (2011) Effect of rest interval on neuromuscular and metabolic responses between children and adolescents. Pediatr Exerc Sci 23:311–321PubMedCrossRef
Callewaert M, Boone J, Celie B, De Clercq D, Bourgois J (2013) Quadriceps muscle fatigue in trained and untrained boys. Int J Sports Med 34:14–20PubMed
Chen TC, Chen HL, Liu YC, Nosaka K (2014) Eccentric exercise-induced muscle damage of pre-adolescent and adolescent boys in comparison to young men. Eur J Appl Physiol 114:1183–1195PubMedCrossRef
Chin ER, Balnave CD, Allen DG (1997) Role of intracellular calcium and metabolites in low-frequency fatigue of mouse skeletal muscle. Am J Physiol 272(2 Pt 1):C550–559PubMedCrossRef
Crone C, Nielsen JB (1989) Methodological implications of the post activation depression of the soleus H-reflex in man. Exp Brain Res 78:28–32PubMedCrossRef
De Ste Croix MBA, Deighan MA, Ratel S, Armstrong N (2009) Age- and sex-associated differences in isokinetic knee muscle endurance between young children and adults. Appl Physiol Nutr Metab 34:725–731PubMedCrossRef
De Luca CJ, Chang SS, Roy SH, Kline JC, Nawab SH (2015) Decomposition of surface EMG signals from cyclic dynamic contractions. J Neurophysiol 113:1941–1951PubMedCrossRef
Dipla K, Tsirini T, Zafeiridis A, Manou V, Dalamitros A, Kellis E, Kellis S (2009) Fatigue resistance during high-intensity intermittent exercise from childhood to adulthood in males and females. Eur J Appl Physiol 106:645–653PubMedCrossRef
Enoka RM (1995) Mechanisms of muscle fatigue: central factors and task dependency. J Electromyogr Kinesiol 5:141–149PubMedCrossRef
Faigenbaum AD, Ratamess NA, McFarland J, Kaczmarek J, Coraggio MJ, Kang J, Hoffman JR (2008) Effect of rest interval length on bench press performance in boys, teens, and men. Pediatr Exerc Sci 20:457–469PubMedCrossRef
Falk B, Dotan R (2006) Child–adult differences in the recovery from high-intensity exercise. Exerc Sport Sci Rev 34:107–112PubMedCrossRef
Farina D, Merletti R, Enoka RM (2004) The extraction of neural strategies from the surface EMG. J Appl Physiol 96:1486–1495PubMedCrossRef
Fleischman A, Makimura H, Stanley TL, McCarthy MA, Kron M, Sun N, Chuzi S, Hrovat MI, Systrom DM, Grinspoon SK (2010) Skeletal muscle phosphocreatine recovery after submaximal exercise in children and young and middle-aged adults. J Clin Endocrinol Metab 95:69–74CrossRef
Folland JP, Williams AG (2007) The adaptations to strength training increased strength. Sport Med 37:145–168CrossRef
Gandevia SC (2001) Spinal and supraspinal factors in human muscle fatigue. Physiol Rev 81:1725–1789CrossRefPubMed
Gandevia SC, Petersen NT, Butler JE, Taylor JL (1999) Impaired response of human motoneurones to corticospinal stimulation after voluntary exercise. J Physiol 521:749–759PubMedPubMedCentralCrossRef
Garcia-Vicencio S, Martin V, Kluka V, Cardenoux C, Jegu AG, Fourot AV, Coudeyre E, Ratel S (2015) Obesity-related differences in neuromuscular fatigue in adolescent girls. Eur J Appl Physiol 115:2421–2432PubMedCrossRef
Glenmark BB, Hedberg GG, Kaijser LL, Jansson EE (1994) Muscle strength from adolescence to adulthood-relationship to muscle fibre types. Eur J Appl Physiol 68:9–19CrossRef
Gorianovas G, Skurvydas A, Streckis V, Brazaitis M, Kamandulis S, McHugh MP (2013) Repeated bout effect was more expressed in young adult males than in elderly males and boys. Biomed Res Int 2013:218970PubMedPubMedCentralCrossRef
Grosset J-F, Mora I, Lambertz D, Pérot C (2008) Voluntary activation of the triceps surae in prepubertal children. J Electromyogr Kinesiol 18:455–465PubMedCrossRef
Halin R, Germain P, Bercier S, Kapitaniak B, Buttelli O (2003) Neuromuscular response of young boys versus men during sustained maximal contraction. Med Sci Sports Exerc 35:1042–1048PubMedCrossRef
Hamada T, Sale DG, MacDougall JD, Tarnopolsky MA (2003) Interaction of fibre type, potentiation and fatigue in human knee extensor muscles. Acta Physiol Scand 178:165–173PubMedCrossRef
Hatzikotoulas K, Patikas D, Bassa E, Hadjileontiadis L, Koutedakis Y, Kotzamanidis C (2009) Submaximal fatigue and recovery in boys and men. Int J Sports Med 30:741–746PubMedCrossRef
Hatzikotoulas K, Patikas D, Ratel S, Bassa E, Kotzamanidis C (2014) Central and peripheral fatigability in boys and men during maximal contraction. Med Sci Sports Exerc 46:1326–1333PubMedCrossRef
Hebestreit H, Mimura K, Bar-Or O (1993) Recovery of muscle power after high-intensity short-term exercise: comparing boys and men. J Appl Physiol 74:2875–2880PubMedCrossRef
Heckman CJ, Gorassini MA, Bennett DJ (2005) Persistent inward currents in motoneuron dendrites: implications for motor output. Muscle Nerve 31:135–156CrossRef
Herbert RD, Gandevia SC (1999) Twitch interpolation in human muscles: mechanisms and implications for measurement of voluntary activation. J Neurophysiol 82:2271–2283PubMedCrossRef
Hultborn H, Meunier S, Pierrot-Deseilligny E, Shindo M (1987) Changes in presynaptic inhibition of Ia fibres at the onset of voluntary contraction in man. J Physiol 389:757–772PubMedPubMedCentralCrossRef
Hunter SK, Critchlow A, Shin I-S, Enoka RM (2004) Fatigability of the elbow flexor muscles for a sustained submaximal contraction is similar in men and women matched for strength. J Appl Physiol 96:195–202PubMedCrossRef
Kanehisa H, Okuyama H, Ikegawa S, Fukunaga T (1995) Fatigability during repetitive maximal knee extensions in 14-year-old boys. Eur J Appl Physiol 72:170–174CrossRef
Kappenstein J, Ferrauti A, Runkel B, Fernandez-Fernandez J, Müller K, Zange J (2013) Changes in phosphocreatine concentration of skeletal muscle during high-intensity intermittent exercise in children and adults. Eur J Appl Physiol 113:2769–2779PubMedCrossRef
Kinugasa R, Akima H, Ota A, Ohta A, Sugiura K, Kuno SY (2004) Short-term creatine supplementation does not improve muscle activation or sprint performance in humans. Eur J Appl Physiol 91:230–237PubMedCrossRef
Kluka V, Martin V, Vicencio SG, Jegu AG, Cardenoux C, Morio C, Coudeyre E, Ratel S (2015) Effect of muscle length on voluntary activation level in children and adults. Med Sci Sports Exerc 47:718–724PubMedCrossRef
Kluka V, Martin V, Vicencio SG, Giustiniani M, Morel C, Morio C, Coudeyre E, Ratel S (2016) Effect of muscle length on voluntary activation of the plantar flexors in boys and men. Eur J Appl Physiol 116:1043–1051PubMedCrossRef
Lazaridis S, Patikas DA, Bassa E, Tsatalas T, Hatzikotoulas K, Ftikas C, Kotzamanidis C (2018) The acute effects of an intense stretch–shortening cycle fatigue protocol on the neuromechanical parameters of lower limbs in men and prepubescent boys. J Sports Sci 36:131–139PubMedCrossRef
Lexell J, Sjöström M, Nordlund AS, Taylor CC (1992) Growth and development of human muscle: a quantitative morphological study of whole vastus lateralis from childhood to adult age. Muscle Nerve 15:404–409PubMedCrossRef
Mademli L, Arampatzis A (2005) Behaviour of the human gastrocnemius muscle architecture during submaximal isometric fatigue. Eur J Appl Physiol 94:611–617PubMedCrossRef
Martin V, Kluka V, Garcia Vicencio S, Maso F, Ratel S (2015) Children have a reduced maximal voluntary activation level of the adductor pollicis muscle compared to adults. Eur J Appl Physiol 115:1485–1491PubMedCrossRef
McNeil CJ, Murray BJ, Rice CL (2006) Differential changes in muscle oxygenation between voluntary and stimulated isometric fatigue of human dorsiflexors. J Appl Physiol 100:890–895PubMedCrossRef
Moalla W, Merzouk A, Costes F, Tabka Z, Ahmaidi S (2006) Muscle oxygenation and EMG activity during isometric exercise in children. J Sports Sci 24:1195–1201PubMedCrossRef
Moalla W, Elloumi M, Chamari K, Dupont G, Maingourd Y, Tabka Z, Ahmaidi S (2012) Training effects on peripheral muscle oxygenation and performance in children with congenital heart diseases. Appl Physiol Nutr Metab 57:1–10
Mosso A (1904) Fatigue. G.P. Putnam's Sons, New York
Murphy JR, Button DC, Chaouachi A, Behm DG (2014) Prepubescent males are less susceptible to neuromuscular fatigue following resistnace exercise. Eur J Appl Physiol 114:825–835PubMedCrossRef
O’Brien TD, Reeves ND, Baltzopoulos V, Jones DA, Maganaris CN (2009) The effects of agonist and antagonist muscle activation on the knee extension moment–angle relationship in adults and children. Eur J Appl Physiol 106:849–856PubMedCrossRef
Paraschos I, Hassani A, Bassa E, Hatzikotoulas K, Patikas D, Kotzamanidis C (2007) Fatigue differences between adults and prepubertal males. Int J Sports Med 28:958–963PubMedCrossRef
Patikas D, Kansizoglou A, Koutlianos N, Williams CA, Hatzikotoulas K, Bassa E, Kotzamanidis C (2013) Fatigue and recovery in children and adults during sustained contractions at two different submaximal intensities. Appl Physiol Nutr Metab 38:953–959PubMedCrossRef
Pierrot-Deseilligny E, Bussel B (1975) Evidence for recurrent inhibition by motoneurons in human subjects. Brain Res 88:105–108PubMedCrossRef
Ploutz-Snyder LL, Tesch PA, Biro RL, Dudley GA (1994) Effect of resistance training on muscle use during exercise. J Appl Physiol 76:1675–1681CrossRef
Psek JA, Cafarelli E (1993) Behavior of coactive muscles during fatigue. J Appl Physiol 74:170–175PubMedCrossRef
Racinais S, Bishop D, Denis R, Lattier G, Mendez-Villaneuva A, Perrey S (2007) Muscle deoxygenation and neural drive to the muscle during repeated sprint cycling. Med Sci Sports Exerc 39:268–274PubMedCrossRef
Ratel S, Blazevich AJ (2017) Are prepubertal children metabolically comparable to well-trained adult endurance athletes? Sports Med 47:1477–1485PubMedCrossRef
Ratel S, Bedu M, Hennegrave A, Doré E, Duché P (2002a) Effects of age and recovery duration on peak power output during repeated cycling sprints. Int J Sports Med 23:397–402PubMedCrossRef
Ratel S, Duche P, Hennegrave A, Van Praagh E, Bedu M (2002b) Acid–base balance during repeated cycling sprints in boys and men. J Appl Physiol 92:479–485PubMedCrossRef
Ratel S, Williams CA, Oliver J, Armstrong N (2004) Effects of age and mode of exercise on power output profiles during repeated sprints. Eur J Appl Physiol 92:204–210PubMedCrossRef
Ratel S, Duché P, Williams CA (2006a) Muscle fatigue during high-intensity exercise in children. Sports Med 6:1031–1065CrossRef
Ratel S, Williams CA, Oliver J, Armstrong N (2006b) Effects of age and recovery duration on performance during multiple treadmill sprints. Int J Sports Med 26:1–8CrossRef
Ratel S, Tonson A, Le Fur Y, Cozzone P, Bendahan D (2008) Comparative analysis of skeletal muscle oxidative capacity in children and adults: a 31P-MRS study. Appl Physiol Nutr Metab 33:720–727PubMedCrossRef
Ratel S, Kluka V, Vicencio SG, Jegu AG, Cardenoux C, Morio C, Coudeyre E, Martin V (2015) Insights into the mechanisms of neuromuscular fatigue in boys and men. Med Sci Sports Exerc 47:2319–2328PubMedCrossRef
Shield A, Zhou S (2004) Assessing voluntary muscle activation with the twitch interpolation technique. Sport Med 34:253–267CrossRef
Smith KJ, Billaut F (2010) Influence of cerebral and muscle oxygenation on repeated-sprint ability. Eur J Appl Physiol 109:989–999PubMedCrossRef
Streckis V, Skurvydas A, Ratkevicius A (2007) Children are more susceptible to central fatigue than adults. Muscle Nerve 36:357–363PubMedCrossRef
Taylor DJ, Kemp GJ, Thompson CH, Radda GK (1997) Ageing: effects on oxidative function of skeletal muscle in vivo. Mol Cell Biochem 174:321–324PubMedCrossRef
Taylor JL, Butler JE, Gandevia SC (2000) Changes in muscle afferents, motoneurons and motor drive during muscle fatigue. Eur J Appl Physiol 83:106–115PubMedCrossRef
Taylor JL, Todd G, Gandevia SC (2006) Evidence for a supraspinal contribution to human muscle fatigue. Clin Exp Pharmacol Physiol 33:400–405PubMedCrossRef
Tonson A, Ratel S, Le Fur Y, Vilmen C, Cozzone PJ, Bendahan D (2010) Muscle energetics changes throughout maturation: a quantitative 31P-MRS analysis. J Appl Physiol 109:1769–1778PubMedPubMedCentralCrossRef
Tucker KJ, Tuncer M, Türker KS (2005) A review of the H-reflex and M-wave in the human triceps surae. Hum Mov Sci 24:667–688PubMedCrossRef
Waugh CM, Blazevich AJ, Fath F, Korff T (2012) Age-related changes in mechanical properties of the Achilles tendon. J Anat 220:144–155PubMedCrossRef
Westerblad H, Lee JA, Lännergren J, Allen DG (1991) Cellular mechanisms of fatigue in skeletal muscle. Am J Med 261:C195–C209
Williams CA, Ratel S (2009) Human muscle fatigue. Routledge, Taylor & Francis Group, London and New YorkCrossRef
Zafeiridis A, Dalamitros A, Dipla K, Manou V, Galanis N, Kellis S (2005) Recovery during high-intensity intermittent anaerobic exercise in boys, teens, and men. Med Sci Sports Exerc 37:505–512PubMedCrossRef
Metadaten
Titel
Exercise-induced fatigue in young people: advances and future perspectives
verfasst von
Dimitrios A. Patikas
Craig A. Williams
Sébastien Ratel
Publikationsdatum
13.02.2018
Verlag
Springer Berlin Heidelberg
Erschienen in
European Journal of Applied Physiology / Ausgabe 5/2018
Print ISSN: 1439-6319
Elektronische ISSN: 1439-6327
DOI
https://doi.org/10.1007/s00421-018-3823-1

Weitere Artikel der Ausgabe 5/2018

European Journal of Applied Physiology 5/2018 Zur Ausgabe

Original Article

Menstrual phase and the vascular response to acute resistance exercise

Original Article

Forearm vasodilator responses to environmental stress and reactive hyperaemia are impaired in young South Asian men

Original Article

Cutaneous neural activity and endothelial involvement in cold-induced vasodilatation

Original Article

The sag response in human muscle contraction

Original Article

Non-linear growth trends of toe flexor muscle strength among children, adolescents, and young adults: a cross-sectional study

Original Article

Cardiorespiratory and perceptual responses to self-regulated and imposed submaximal arm–leg ergometry

Neu im Fachgebiet Arbeitsmedizin

Open Access 27.03.2024 | ADHS | Leitthema

Elterliches Belastungserleben, Unaufmerksamkeits‑/Hyperaktivitätssymptome und elternberichtete ADHS bei Kindern und Jugendlichen: Ergebnisse aus der KiGGS-Studie

Open Access 25.03.2024 | Leitthema

Substanzkonsum und Nutzung von sozialen Medien, Computerspielen und Glücksspielen unter Auszubildenden an beruflichen Schulen

19.03.2024 | Leitthema

Berufsbelastung und Stressbewältigung von weiblichen und männlichen Auszubildenden

19.03.2024 | COVID-19 | Leitthema

Rauschtrinken in der frühen Adoleszenz
Ergebnisse des Präventionsradars von 2016 bis 2023