Skip to main content
main-content

01.12.2017 | Research article | Ausgabe 1/2017 Open Access

BMC Public Health 1/2017

Exhaled carbon monoxide: a non-invasive biomarker of short-term exposure to outdoor air pollution

Zeitschrift:
BMC Public Health > Ausgabe 1/2017
Autoren:
Herve Lawin, Lucie Ayi Fanou, Vikkey Hinson, Jacqueline Wanjiku, N. Kingsley Ukwaja, Stephen B Gordon, Benjamin Fayomi, John R Balmes, Parfait Houngbegnon, Euripide Avokpaho, Ambaliou Sanni
Wichtige Hinweise

Electronic supplementary material

The online version of this article (doi:10.​1186/​s12889-017-4243-6) contains supplementary material, which is available to authorized users.

Abstract

Background

In urban settings of Africa with rapidly increasing population, traffic-related air pollution is a major contributor to outdoor air pollution (OAP). Although OAP has been identified as a leading cause of global morbidity and mortality, there is however, lack of a simple biomarker to assess levels of exposure to OAP in resource-poor settings. This study evaluated the role of exhaled carbon monoxide (exhCO) as a potential biomarker of exposure to ambient carbon monoxide (ambCO) from OAP.

Methods

This was a descriptive study conducted among male commercial motorcycle riders in Cotonou – the economic capital of Benin. The participants’ AmbCO was measured using a portable carbon monoxide (CO) data logger for 8 h during the period of their shift. ExhCO was measured just before and immediately after their shift (8-h) Participants were asked not to cook or to smoke during the day of the measurements. Linear regression analysis was used to assess the association between ambCO and exhCO for the last 2, 4 and 6 h of their shift.

Results

Of 170 participants who completed the study, their mean ± SD age was 42.2 ± 8.4 years, and their mean ± SD daily income was 7.3 ± 2.7$. Also, 95% of the participants’ used solid fuels for cooking and only 2% had ever smoked. Average exhCO increased by 5.1 ppm at the end of the shift (p = 0.004). Post-shift exhCO was significantly associated to ambCO, this association was strongest for the last 2 h of OAP exposure before exhCO measurement (β = 0.34, p < 0.001).

Conclusion

ExhCO level was associated with recent exposure to ambCO from OAP with measurable increase after 8 h of exposure. These findings suggest that ExhCO may be a potential biomarker of short-term exposure to OAP.
Zusatzmaterial
Literatur
Über diesen Artikel

Weitere Artikel der Ausgabe 1/2017

BMC Public Health 1/2017 Zur Ausgabe