nach oben

Pediatric Surgery International

Erschienen in:

28.07.2018 | Original Article

Experimental validation of laryngotracheal growth and recurrent laryngeal nerve preservation after partial cricotracheal resection in a growing rabbit model

verfasst von: Keiichi Morita, Kosaku Maeda, Insu Kawahara, Yuko Bitoh

Erschienen in: Pediatric Surgery International | Ausgabe 10/2018

Einloggen, um Zugang zu erhalten

Abstract

Purpose

The aim of this study was to confirm laryngotracheal growth and recurrent laryngeal nerve (RLN) preservation after partial cricotracheal resection (PCTR) in a growing rabbit model by performing the procedure in pediatric animals.

Methods

Six female Japanese white rabbits, 12 weeks of age, underwent PCTR. The course of the RLN was evaluated during surgery (n = 3). Endoscopic and histologic examinations were performed at 22 weeks of age (n = 6). Four non-operated rabbits, 22 weeks of age, underwent endoscopic and histologic examinations as controls.

Results

The RLN was preserved at the esophageal side and entered the larynx behind the cricothyroid joint after PCTR. Endoscopic examination showed normal vocal cord movements and the large reconstructed subglottis. Histologically, sufficient submucosal vessels and cartilage growth were identified at the reconstructed larynx. The median inside luminal area at the anastomotic site in the PCTR group was 24.8 mm² (range 21.8–29.0 mm²), and that at the cricoid cartilage and trachea in the control group was 23.4 mm² (range 20.0–26.6 mm²) and 25.6 mm² (range 22.9–28.8 mm²), respectively.

Conclusion

No interference with laryngotracheal growth was seen, and RLN preservation was confirmed after PCTR. Use of PCTR in the pediatric age group seems appropriate.

Jefferson ND, Cohen AP, Rutter MJ (2016) Subglottic stenosis. Semin Pediatr Surg 25:138–143. https://doi.org/10.1053/j.sempedsurg.2016.02.006 CrossRefPubMed

Morita K, Yokoi A, Bitoh Y, Fukuzawa H, Okata Y, Iwade T, Endo K, Takemoto J, Tamaki A, Maeda K (2015) Severe acquired subglottic stenosis in children: analysis of clinical features and surgical outcomes based on the range of stenosis. Pediatr Surg Int 31:943–937. https://doi.org/10.1007/s00383-015-3773-1 CrossRefPubMed

Hartnick CJ, Hartley BE, Lacy PD, Liu J, Willging JP, Myer CM 3rd, Cotton RT (2001) Surgery for pediatric subglottic stenosis: disease-specific outcomes. Ann Otol Rhinol Laryngol 110:1109–1113CrossRefPubMed

Yamamoto K, Monnier P, Holtz F, Jaquet Y (2014) Laryngotracheal reconstruction for pediatric glotto-subglottic stenosis. Int J Pediatr Otorhinolaryngol 78:1476–1479. https://doi.org/10.1016/j.ijporl.2014.06.012 CrossRefPubMed

White DR, Cotton RT, Bean JA, Rutter MJ (2005) Pediatric cricotracheal resection: surgical outcomes and risk factor analysis. Arch Otolaryngol Head Neck Surg 131:896–899CrossRefPubMed

Yamamoto K, Jaquet Y, Ikonomidis C, Monnier P (2015) Partial cricotracheal resection for paediatric subglottic stenosis: update of the Lausanne experience with 129 cases. Eur J Cardiothorac Surg 47:876–882. https://doi.org/10.1093/ejcts/ezu273 CrossRefPubMed

Monnier P, Savary M, Chapuis G (1993) Partial cricoid resection with primary tracheal anastomosis for subglottic stenosis in infants and children. Laryngoscope 103:1273–1283CrossRefPubMed

Stern Y, Gerber ME, Walner DL, Cotton RT (1997) Partial cricotracheal resection with primary anastomosis in the pediatric age group. Ann Otol Rhinol Laryngol 106:891–896CrossRefPubMed

Monnier P (2011) Partial cricotracheal resection. In: Monnier P (ed) Pediatric airway surgery: management of laryngotracheal stenosis in infants and children. Springer, Berlin, pp 279–321. https://doi.org/10.1007/978-3-642-13535-4_20 CrossRef

10.

Nofal AA, El-Anwar MW (2016) Recurrent laryngeal nerve identification in thyroidectomy by intra-operative staining with methylene blue in forty-six patients. Clin Otolaryngol 41:296–299. https://doi.org/10.1111/coa.12509 CrossRefPubMed

11.

Monnier P, Lang F, Savary M (1998) Partial cricotracheal resection for severe pediatric subglottic stenosis: update of the Lausanne experience. Ann Otol Rhinol Laryngol 107:961–968CrossRefPubMed

12.

Sullivan MJ, McClatchey KD, Passamani PP (1987) Airway growth following cricotracheal resection in puppies. Arch Otolaryngol Head Neck Surg 113:606–611CrossRefPubMed

13.

Ward RF, Triglia JM (2000) Airway growth after cricotracheal resection in a rabbit model and clinical application to the treatment of subglottic stenosis in children. Laryngoscope 110:835–844CrossRefPubMed

14.

Weidenbecher M, Amann K, Iro H (2003) Laryngotracheal growth following cricotracheal resection combined with laminotomy. An experimental study on rabbits. Ann Otol Rhinol Laryngol 112:697–703CrossRefPubMed

15.

Salassa JR, Pearson BW, Payne WS (1977) Gross and microscopical blood supply of the trachea. Ann Thorac Surg 24:100–107CrossRefPubMed

16.

Manuel D (2016) Recurrent laryngeal nerve branching. In: Randolph GW (ed) Recurrent laryngeal nerve and superior laryngeal nerve. Springer, Switzerland, pp 83–93. https://doi.org/10.1007/978-3-319-27727-1 CrossRef

17.

Alvarez-Neri H, Penchyna-Grub J, Porras-Hernandez JD, Blanco-Rodriguez G, Gonzalez R, Rutter MJ (2005) Primary cricotracheal resection with thyrotracheal anastomosis for the treatment of severe subglottic stenosis in children and adolescents. Ann Otol Rhinol Laryngol 114:2–6CrossRefPubMed

18.

Lee M (1969) A selective stain to detect the vagus nerve in the operation of vagotomy. Br J Surg 56:10–13CrossRefPubMed

19.

Ryan S, McNicholas WT, O’Regan RG, Nolan P (2003) Intralaryngeal neuroanatomy of the recurrent laryngeal nerve of the rabbit. J Anat 202:421–430CrossRefPubMedPubMedCentral

Titel: Experimental validation of laryngotracheal growth and recurrent laryngeal nerve preservation after partial cricotracheal resection in a growing rabbit model
verfasst von: Keiichi Morita
Kosaku Maeda
Insu Kawahara
Yuko Bitoh
Publikationsdatum: 28.07.2018
Verlag: Springer Berlin Heidelberg
Erschienen in: Pediatric Surgery International / Ausgabe 10/2018
Print ISSN: 0179-0358
Elektronische ISSN: 1437-9813
DOI: https://doi.org/10.1007/s00383-018-4314-5

Neu im Fachgebiet Pädiatrie

23.04.2024 | Typ-1-Diabetes | Nachrichten

Update Pädiatrie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen

Springer Medizin

Experimental validation of laryngotracheal growth and recurrent laryngeal nerve preservation after partial cricotracheal resection in a growing rabbit model

Abstract

Purpose

Methods

Results

Conclusion

Neu im Fachgebiet Pädiatrie

Neuer Typ-1-Diabetes bei Kindern am Wochenende eher übersehen

Neue Studienergebnisse zur Myopiekontrolle mit Atropin

Spinale Muskelatrophie: Neugeborenen-Screening lohnt sich

Fünf Dinge, die im Kindernotfall besser zu unterlassen sind

Update Pädiatrie

Springer Medizin

Abstract

Purpose

Methods

Results

Conclusion

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 10/2018

Congenital hyperinsulinism treated by surgical resection of the hyperplastic lesion which had been preoperatively diagnosed by 18F-DOPA PET examination in Japan: a nationwide survey

Introduction of resection of intrahepatic bile duct stenosis-causing membrane or septum into laparoscopic choledochal cyst excision

The effect of the broad-spectrum antibiotics for prevention of postoperative intra-abdominal abscess in pediatric acute appendicitis

Oral administration of eicosapentaenoic acid suppresses liver fibrosis in postoperative patients with biliary atresia

Single-stage laparoscopic transanal pull-through modified Swenson procedure without leaving a muscular cuff for short- and long-type Hirschsprung disease: a comparative study

Clinical features and risk factors of bile duct perforation associated with pediatric congenital biliary dilatation

Neu im Fachgebiet Pädiatrie

Neuer Typ-1-Diabetes bei Kindern am Wochenende eher übersehen

Neue Studienergebnisse zur Myopiekontrolle mit Atropin

Spinale Muskelatrophie: Neugeborenen-Screening lohnt sich

Fünf Dinge, die im Kindernotfall besser zu unterlassen sind

Update Pädiatrie