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03.09.2024 | CLINICAL PAPER

Exploring Malignant Odontogenic Tumors: Clinical Insights & Literature Analysis

verfasst von: Ferhana Firoz Maliyekkal, Sandeep Vijay, Anoop Attakkil, Faseela Beegum, Ashwathi Krishnan, Aswin Mullath

Erschienen in: Journal of Maxillofacial and Oral Surgery

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Abstract

Introduction

Malignant odontogenic tumors (MOT) are rare malignancies arising either denovo from tooth forming tissues or as malignant transformation of benign odontogenic lesions. Owing to its rarity, there is no available staging or defined evaluation/ treatment guidelines available.

Aim

The aim of this study was to report a case series of six MOT cases, to study their clinicoradiological findings at presentation and available treatment modalities.

Methodology

Data of the patients were collected from medical records including electronic medical records and the pathology reporting section.

Results and Conclusion

Our study showed that all patients who were treated with surgery and adjuvant radiation remained disease free during follow-up. Thus, we recommend that all MOTs should be treated with radical resection followed by adjuvant radiation.
Literatur
1.
Zurück zum Zitat Carlson ER (2016) Malignant odontogenic tumors. J Oral Maxillofac Surg 74(5):877–878CrossRef Carlson ER (2016) Malignant odontogenic tumors. J Oral Maxillofac Surg 74(5):877–878CrossRef
2.
Zurück zum Zitat Soluk-Tekkesin M, Wright JM (2022) The world health organization classification of odontogenic lesions: a summary of the changes of the 2022 (5th) edition. Turk PatolojiDerg 38(2):168–184 Soluk-Tekkesin M, Wright JM (2022) The world health organization classification of odontogenic lesions: a summary of the changes of the 2022 (5th) edition. Turk PatolojiDerg 38(2):168–184
3.
4.
Zurück zum Zitat Avelar RL, Primo BT, Pinheiro-Nogueira CB, Studart-Soares EC, de Oliveira RB, Romulo De Medeiros J et al (2011) Worldwide incidence of odontogenic tumors. J Craniofac Surg 22(6):2118–2123CrossRefPubMed Avelar RL, Primo BT, Pinheiro-Nogueira CB, Studart-Soares EC, de Oliveira RB, Romulo De Medeiros J et al (2011) Worldwide incidence of odontogenic tumors. J Craniofac Surg 22(6):2118–2123CrossRefPubMed
5.
Zurück zum Zitat Silva LPD, Macedo RADP, Serpa MS, Sobral APV, Souza LBD (2017) Global frequency of benign and malignant odontogenic tumors according to the 2005 WHO classification. JORDI - J Oral Diagn 2:1–8CrossRef Silva LPD, Macedo RADP, Serpa MS, Sobral APV, Souza LBD (2017) Global frequency of benign and malignant odontogenic tumors according to the 2005 WHO classification. JORDI - J Oral Diagn 2:1–8CrossRef
6.
Zurück zum Zitat Lim D, Tan CC, Tilakaratne WM, Goh YC (2022) Sclerosing odontogenic carcinoma - review of all published cases: is it a justifiable addition as a malignancy? Braz J Otorhinolaryngol 88(1):118–129CrossRefPubMed Lim D, Tan CC, Tilakaratne WM, Goh YC (2022) Sclerosing odontogenic carcinoma - review of all published cases: is it a justifiable addition as a malignancy? Braz J Otorhinolaryngol 88(1):118–129CrossRefPubMed
7.
Zurück zum Zitat Koutlas IG, Allen CM, Warnock GR, Manivel JC (2008) Sclerosing odontogenic carcinoma: a previously unreported variant of a locally aggressive odontogenic neoplasm without apparent metastatic potential. Am J Surg Pathol 32(11):1613–1619CrossRefPubMed Koutlas IG, Allen CM, Warnock GR, Manivel JC (2008) Sclerosing odontogenic carcinoma: a previously unreported variant of a locally aggressive odontogenic neoplasm without apparent metastatic potential. Am J Surg Pathol 32(11):1613–1619CrossRefPubMed
8.
Zurück zum Zitat Deng L, Wang R, Yang M, Li W, Zou L (2019) Ameloblastic carcinoma: clinicopathological analysis of 18 cases and a systematic review. Head Neck 41(12):4191–4198CrossRefPubMed Deng L, Wang R, Yang M, Li W, Zou L (2019) Ameloblastic carcinoma: clinicopathological analysis of 18 cases and a systematic review. Head Neck 41(12):4191–4198CrossRefPubMed
10.
Zurück zum Zitat Bilodeau EA, Weinreb I, Antonescu CR, Zhang L, Dacic S, Muller S et al (2013) Clear cell odontogenic carcinomas show EWSR1 rearrangements: a novel finding and a biological link to salivary clear cell carcinomas. Am J Surg Pathol 37(7):1001–1005CrossRefPubMed Bilodeau EA, Weinreb I, Antonescu CR, Zhang L, Dacic S, Muller S et al (2013) Clear cell odontogenic carcinomas show EWSR1 rearrangements: a novel finding and a biological link to salivary clear cell carcinomas. Am J Surg Pathol 37(7):1001–1005CrossRefPubMed
11.
Zurück zum Zitat Jia MQ, Jia J, Wang L, Zou HX (2019) Ghost cell odontogenic carcinoma of the jaws: report of two cases and a literature review. World J Clin Cases 7(3):357–365CrossRefPubMedPubMedCentral Jia MQ, Jia J, Wang L, Zou HX (2019) Ghost cell odontogenic carcinoma of the jaws: report of two cases and a literature review. World J Clin Cases 7(3):357–365CrossRefPubMedPubMedCentral
12.
Zurück zum Zitat Chan KC, Pharoah M, Lee L, Weinreb I, Perez-Ordonez B (2013) Intraosseous mucoepidermoid carcinoma: a review of the diagnostic imaging features of four jaw cases. DentoMaxillo Facial Radiol 42(4):20110162CrossRef Chan KC, Pharoah M, Lee L, Weinreb I, Perez-Ordonez B (2013) Intraosseous mucoepidermoid carcinoma: a review of the diagnostic imaging features of four jaw cases. DentoMaxillo Facial Radiol 42(4):20110162CrossRef
13.
Zurück zum Zitat Waldron CA, Mustoe TA (1989) Primary intraosseous carcinoma of the mandible with probable origin in an odontogenic cyst. Oral Surg Oral Med Oral Pathol 67(6):716–724CrossRefPubMed Waldron CA, Mustoe TA (1989) Primary intraosseous carcinoma of the mandible with probable origin in an odontogenic cyst. Oral Surg Oral Med Oral Pathol 67(6):716–724CrossRefPubMed
14.
Zurück zum Zitat Sathasivam HP, Saw CL, Lau SH (2021) Clinico-pathological study of malignant odontogenic tumours from a national referral centre. BMC Oral Health 21(1):129CrossRefPubMedPubMedCentral Sathasivam HP, Saw CL, Lau SH (2021) Clinico-pathological study of malignant odontogenic tumours from a national referral centre. BMC Oral Health 21(1):129CrossRefPubMedPubMedCentral
15.
16.
Zurück zum Zitat Da Silva L, Serpa M, Tenorio J, Do Nascimento G, De Souza AE, Veras-Sobral A (2016) Retrospective study of 289 odontogenic tumors in a Brazilian population. Med Oral Patol Oral CirugiaBucal 21(3):e271–e275CrossRef Da Silva L, Serpa M, Tenorio J, Do Nascimento G, De Souza AE, Veras-Sobral A (2016) Retrospective study of 289 odontogenic tumors in a Brazilian population. Med Oral Patol Oral CirugiaBucal 21(3):e271–e275CrossRef
17.
Zurück zum Zitat Goldenberg D, Sciubba J, Koch W, Tufano RP (2004) Malignant odontogenic tumors: a 22-year experience. Laryngoscope 114(10):1770–1774CrossRefPubMed Goldenberg D, Sciubba J, Koch W, Tufano RP (2004) Malignant odontogenic tumors: a 22-year experience. Laryngoscope 114(10):1770–1774CrossRefPubMed
18.
Zurück zum Zitat Agarwal S, Mark J, Xie C, Ghulam E, Patil Y (2016) Survival and prognosis for malignant tumors of odontogenic origin. Otolaryngol-Head Neck Surg Off J Am AcadOtolaryngol-Head Neck Surg 155(1):113–116CrossRef Agarwal S, Mark J, Xie C, Ghulam E, Patil Y (2016) Survival and prognosis for malignant tumors of odontogenic origin. Otolaryngol-Head Neck Surg Off J Am AcadOtolaryngol-Head Neck Surg 155(1):113–116CrossRef
Metadaten
Titel
Exploring Malignant Odontogenic Tumors: Clinical Insights & Literature Analysis
verfasst von
Ferhana Firoz Maliyekkal
Sandeep Vijay
Anoop Attakkil
Faseela Beegum
Ashwathi Krishnan
Aswin Mullath
Publikationsdatum
03.09.2024
Verlag
Springer India
Erschienen in
Journal of Maxillofacial and Oral Surgery
Print ISSN: 0972-8279
Elektronische ISSN: 0974-942X
DOI
https://doi.org/10.1007/s12663-024-02325-y

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