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01.12.2012 | Research article | Ausgabe 1/2012 Open Access

BMC Health Services Research 1/2012

Factors affecting hospital stay in psychiatric patients: the role of active comorbidity

BMC Health Services Research > Ausgabe 1/2012
Athanassios Douzenis, Dionysios Seretis, Stella Nika, Paraskevi Nikolaidou, Athanassia Papadopoulou, Emmanouil N Rizos, Christos Christodoulou, Christos Tsopelas, Dominic Mitchell, Lefteris Lykouras
Wichtige Hinweise

Electronic supplementary material

The online version of this article (doi:10.​1186/​1472-6963-12-166) contains supplementary material, which is available to authorized users.

Competing interests

The authors declare that they have no competing interests.

Authors’ contributions

AD was the principal investigator of the research study; he conceived and designed the study, coordinated the research process, wrote part of the paper and corrected the final draft. DS contributed to the conception and design of the study, coordinated the research, carried out the statistical analysis, wrote part of the paper and contributed to the final draft. SN, PN, AP, ENR, CC and CT collected the data and wrote part of the paper. DM wrote part of the paper and was responsible together with AD, DS and LL for the final draft. LL had the overall overseeing of the research, read and corrected the paper and was responsible together with AD and DS for ethical approval. All authors have read and approved the manuscript.



Research on length of stay (LOS) of psychiatric inpatients is an under-investigated issue. In this naturalistic study factors which affect LOS of two groups of patients were investigated, focusing on the impact on LOS of medical comorbidity severe enough to require referral.


Active medical comorbidity was quantified using referral as the criterion. The study sample consisted of 200 inpatients with the diagnosis of schizophrenia and 228 inpatients suffering from bipolar disorder (type I or II). Jonckheere and Mann–Whitney tests were used to estimate the influence of referrals on LOS, and regression analyses isolated variables associated with LOS separately for each group.


Half of the patients needed one or more referrals for a non-psychiatric problem. The most common medical condition of patients with bipolar disorder was arterial hypertension. Inpatients with schizophrenia suffered mostly from an endocrine/metabolic disease - 12% of referrals were for Hashimoto’s thyroiditis. A positive linear trend was found between LOS and number of referrals; the effect was greater for schizophrenia patients. The effect of referrals on LOS was verified by regression in both groups. Overall, referred patients showed greater improvement in GAF compared to controls.


To our knowledge this was the first study to investigate physical comorbidity in psychiatric inpatients using the criterion of referral to medical subspecialties. Comorbidity severe enough to warrant referral is a significant determinant of hospital stay. This insight may prove useful in health care planning. The results show lack of effective community care in the case of schizophrenia and negative symptoms may be the cause of this. Our findings call for more attention to be paid to the general medical needs of inpatients with severe mental health and concurrent severe medical comorbidity.
Authors’ original file for figure 1
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