01.08.2008 | Original Article | Ausgabe 8/2008
Family history as a risk factor for pelvic organ prolapse
- Zeitschrift:
- International Urogynecology Journal > Ausgabe 8/2008
Wichtige Hinweise
Presented at Central Association of Obstetricians and Gynecologists Awarded George W. Morley Paper Award Chicago, IL, USA, 17 October 2007
Abstract
The aim of this study was to determine whether a family history of prolapse and/or hernia is a risk factor for prolapse. A cohort of 458 women seeking gynecological care was classified as exposed (family history) or unexposed (without family history). We used χ
2 to assess confounding and logistic regression to determine risk. Nearly half (47.3%) of the 458 participants reported a positive family history. Of these, 52.5% had prolapse. This was significantly higher than the 28.9% rate of prolapse in women without a family history (p < 0.001). The crude risk ratio for family history of prolapse and/or hernia and prolapse was 1.8 (95% CI 1.4–2.3). After adjusting for vaginal deliveries, incontinence, and hysterectomy, the risk of prolapse was 1.4 (95% CI 1.2–1.8) times higher in women with a family history of prolapse and/or hernia. Heredity is a risk factor for prolapse. History taking should include both male and female family members.
