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Erschienen in: Knee Surgery, Sports Traumatology, Arthroscopy 8/2018

16.02.2018 | Hip

Fascia iliaca blockade with the addition of liposomal bupivacaine vs. plain bupivacaine for perioperative pain management following hip arthroscopy

verfasst von: Richard L. Purcell, Kyle E. Nappo, Daniel W. Griffin, Michael McCabe, Terrence Anderson, Michael Kent

Erschienen in: Knee Surgery, Sports Traumatology, Arthroscopy | Ausgabe 8/2018

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Abstract

Purpose

A newer formulation of bupivacaine, encapsulated within carrier molecules, has garnered attention for its role in providing extended post-operative analgesia. The purpose was to evaluate the addition of liposomal bupivacaine to fascia iliaca blockade during hip arthroscopy.

Methods

Retrospective cohort study of patients undergoing hip arthroscopy with a pre-operative fascia iliaca blockade with either liposomal bupivacaine (Group 1; 266mg + 20 cc 0.5% plain bupivacaine) or bupivacaine (Group 2; 40 cc 0.25% plain bupivacaine). All patients received standardized pre-operative oral pain medications. The primary outcome was the defense veteran pain rating scale (DVPRS). Secondary outcomes included duration of hospital admission, PACU opioid use, PACU pain scores, and duration of nerve blockade.

Results

Thirty-eight males and 30 females, mean age of 33 years (range 14–56). There was no difference in pre-operative DVPRS between the groups (n.s.). There was no difference in post-operative DVPRS pain scores at POD0 (3.7 vs. 3.9, n.s.), POD1 (4.2 vs. 3.8, n.s.), POD2 (4.2 vs. 3.7, n.s.), POD3 (3.9 vs. 3.7, n.s.) or POD14 (2.2 vs. 2.4, n.s.). Group 1 trended towards longer mean total hospital admission time (872 vs. 822 min, n.s.), and greater mean morphine equivalents administered in the PACU (33 vs. 29 mg, n.s.). 68% of patients in group 1 reported continued anterior thigh numbness at POD3, compared to 34% in group 2 (p = 0.008).

Conclusions

Despite the advertised benefits of prolonged post-operative analgesia using liposomal bupivacaine, there were no significant differences in post-operative pain scores or PACU opioid consumption. Our results support that acceptable pain scores are successfully achieved at all time periods with the use of multimodal analgesia including fascia iliaca blockade despite the type of pain medication administered.

Level of evidence

III.
Literatur
1.
Zurück zum Zitat (1973) Evaluation of a local anesthetic agent. Bupivacaine hydrochloride (Marcaine). JAMA 224:1035–1036 (Editorial) (1973) Evaluation of a local anesthetic agent. Bupivacaine hydrochloride (Marcaine). JAMA 224:1035–1036 (Editorial)
2.
Zurück zum Zitat Abildgaard JT, Lonergan KT, Tolan SJ, Kissenberth MJ, Hawkins RJ, Washburn R 3rd et al. (2017) Liposomal bupivacaine versus indwelling interscalene nerve block for postoperative pain control in shoulder arthroplasty: a prospective randomized controlled trial. J Shoulder Elbow Surg 26:1175–1181CrossRefPubMed Abildgaard JT, Lonergan KT, Tolan SJ, Kissenberth MJ, Hawkins RJ, Washburn R 3rd et al. (2017) Liposomal bupivacaine versus indwelling interscalene nerve block for postoperative pain control in shoulder arthroplasty: a prospective randomized controlled trial. J Shoulder Elbow Surg 26:1175–1181CrossRefPubMed
3.
Zurück zum Zitat Alijanipour P, Tan TL, Matthews CN, Viola JR, Purtill JJ, Rothman RH et al (2017) Periarticular injection of liposomal bupivacaine offers no benefit over standard bupivacaine in total knee arthroplasty: a prospective, randomized, controlled trial. J Arthroplasty 32:628–634CrossRefPubMed Alijanipour P, Tan TL, Matthews CN, Viola JR, Purtill JJ, Rothman RH et al (2017) Periarticular injection of liposomal bupivacaine offers no benefit over standard bupivacaine in total knee arthroplasty: a prospective, randomized, controlled trial. J Arthroplasty 32:628–634CrossRefPubMed
4.
Zurück zum Zitat Bozic KJ, Chan V, Valone FH 3rd, Feeley BT, Vail TP (2013) Trends in hip arthroscopy utilization in the United States. J Arthroplasty 28:140–143CrossRefPubMed Bozic KJ, Chan V, Valone FH 3rd, Feeley BT, Vail TP (2013) Trends in hip arthroscopy utilization in the United States. J Arthroplasty 28:140–143CrossRefPubMed
5.
Zurück zum Zitat Bramlett K, Onel E, Viscusi ER, Jones K (2012) A randomized, double-blind, dose-ranging study comparing wound infiltration of DepoFoam bupivacaine, an extended-release liposomal bupivacaine, to bupivacaine HCl for postsurgical analgesia in total knee arthroplasty. Knee 19:530–536CrossRefPubMed Bramlett K, Onel E, Viscusi ER, Jones K (2012) A randomized, double-blind, dose-ranging study comparing wound infiltration of DepoFoam bupivacaine, an extended-release liposomal bupivacaine, to bupivacaine HCl for postsurgical analgesia in total knee arthroplasty. Knee 19:530–536CrossRefPubMed
6.
Zurück zum Zitat Buckenmaier CC, 3rd, Galloway KT, Polomano RC, McDuffie M, Kwon N, Gallagher RM (2013) Preliminary validation of the defense and veterans pain rating scale (DVPRS) in a military population. Pain Med 14:110–123CrossRefPubMed Buckenmaier CC, 3rd, Galloway KT, Polomano RC, McDuffie M, Kwon N, Gallagher RM (2013) Preliminary validation of the defense and veterans pain rating scale (DVPRS) in a military population. Pain Med 14:110–123CrossRefPubMed
7.
Zurück zum Zitat Dalens B, Tanguy A, Vanneuville G (1989) Lumbar plexus blocks and lumbar plexus nerve blocks. Anesth Analg 69:852–854CrossRefPubMed Dalens B, Tanguy A, Vanneuville G (1989) Lumbar plexus blocks and lumbar plexus nerve blocks. Anesth Analg 69:852–854CrossRefPubMed
8.
Zurück zum Zitat Golf M, Daniels SE, Onel E (2011) A phase 3, randomized, placebo-controlled trial of DepoFoam(R) bupivacaine (extended-release bupivacaine local analgesic) in bunionectomy. Adv Ther 28:776–788CrossRefPubMed Golf M, Daniels SE, Onel E (2011) A phase 3, randomized, placebo-controlled trial of DepoFoam(R) bupivacaine (extended-release bupivacaine local analgesic) in bunionectomy. Adv Ther 28:776–788CrossRefPubMed
9.
Zurück zum Zitat Gorfine SR, Onel E, Patou G, Krivokapic ZV (2011) Bupivacaine extended-release liposome injection for prolonged postsurgical analgesia in patients undergoing hemorrhoidectomy: a multicenter, randomized, double-blind, placebo-controlled trial. Dis Colon Rectum 54:1552–1559CrossRefPubMed Gorfine SR, Onel E, Patou G, Krivokapic ZV (2011) Bupivacaine extended-release liposome injection for prolonged postsurgical analgesia in patients undergoing hemorrhoidectomy: a multicenter, randomized, double-blind, placebo-controlled trial. Dis Colon Rectum 54:1552–1559CrossRefPubMed
10.
Zurück zum Zitat Hebbard P, Ivanusic J, Sha S (2011) Ultrasound-guided supra-inguinal fascia iliaca block: a cadaveric evaluation of a novel approach. Anaesthesia 66:300–305CrossRefPubMed Hebbard P, Ivanusic J, Sha S (2011) Ultrasound-guided supra-inguinal fascia iliaca block: a cadaveric evaluation of a novel approach. Anaesthesia 66:300–305CrossRefPubMed
11.
Zurück zum Zitat Ilfeld BM, Malhotra N, Furnish TJ, Donohue MC, Madison SJ (2013) Liposomal bupivacaine as a single-injection peripheral nerve block: a dose–response study. Anesth Analg 117:1248–1256CrossRefPubMed Ilfeld BM, Malhotra N, Furnish TJ, Donohue MC, Madison SJ (2013) Liposomal bupivacaine as a single-injection peripheral nerve block: a dose–response study. Anesth Analg 117:1248–1256CrossRefPubMed
12.
Zurück zum Zitat Kay J, de Sa D, Memon M, Simunovic N, Paul J, Ayeni OR (2016) Examining the role of perioperative nerve blocks in hip arthroscopy: a systematic review. Arthroscopy 32:704–715 (e701) CrossRefPubMed Kay J, de Sa D, Memon M, Simunovic N, Paul J, Ayeni OR (2016) Examining the role of perioperative nerve blocks in hip arthroscopy: a systematic review. Arthroscopy 32:704–715 (e701) CrossRefPubMed
13.
Zurück zum Zitat Krych AJ, Baran S, Kuzma SA, Smith HM, Johnson RL, Levy BA (2014) Utility of multimodal analgesia with fascia iliaca blockade for acute pain management following hip arthroscopy. Knee Surg Sports Traumatol Arthrosc 22:843–847CrossRefPubMed Krych AJ, Baran S, Kuzma SA, Smith HM, Johnson RL, Levy BA (2014) Utility of multimodal analgesia with fascia iliaca blockade for acute pain management following hip arthroscopy. Knee Surg Sports Traumatol Arthrosc 22:843–847CrossRefPubMed
14.
Zurück zum Zitat Kuang MJ, Du Y, Ma JX, He W, Fu L, Ma XL (2017) The efficacy of liposomal bupivacaine using periarticular injection in total knee arthroplasty: a systematic review and meta-analysis. J Arthroplasty 32:1395–1402CrossRefPubMed Kuang MJ, Du Y, Ma JX, He W, Fu L, Ma XL (2017) The efficacy of liposomal bupivacaine using periarticular injection in total knee arthroplasty: a systematic review and meta-analysis. J Arthroplasty 32:1395–1402CrossRefPubMed
15.
Zurück zum Zitat Kumar K, Pandey RK, Bhalla AP, Kashyap L, Garg R, Darlong V et al (2015) Comparison of conventional infrainguinal versus modified proximal suprainguinal approach of fascia iliaca compartment block for postoperative analgesia in total hip arthroplasty. A prospective randomized study. Acta Anaesthesiol Belg 66:95–100PubMed Kumar K, Pandey RK, Bhalla AP, Kashyap L, Garg R, Darlong V et al (2015) Comparison of conventional infrainguinal versus modified proximal suprainguinal approach of fascia iliaca compartment block for postoperative analgesia in total hip arthroplasty. A prospective randomized study. Acta Anaesthesiol Belg 66:95–100PubMed
16.
Zurück zum Zitat Maradit Kremers H, Schilz SR, Van Houten HK, Herrin J, Koenig KM, Bozic KJ et al (2017) Trends in utilization and outcomes of hip arthroscopy in the United States between 2005 and 2013. J Arthroplasty 32:750–755CrossRefPubMed Maradit Kremers H, Schilz SR, Van Houten HK, Herrin J, Koenig KM, Bozic KJ et al (2017) Trends in utilization and outcomes of hip arthroscopy in the United States between 2005 and 2013. J Arthroplasty 32:750–755CrossRefPubMed
17.
Zurück zum Zitat McGraw-Tatum MA, Groover MT, George NE, Urse JS, Heh V (2017) A prospective, randomized trial comparing liposomal bupivacaine vs fascia iliaca compartment block for postoperative pain control in total hip arthroplasty. J Arthroplasty 32:2181–2185CrossRefPubMed McGraw-Tatum MA, Groover MT, George NE, Urse JS, Heh V (2017) A prospective, randomized trial comparing liposomal bupivacaine vs fascia iliaca compartment block for postoperative pain control in total hip arthroplasty. J Arthroplasty 32:2181–2185CrossRefPubMed
19.
Zurück zum Zitat Nassif TH, Hull A, Holliday SB, Sullivan P, Sandbrink F (2015) Concurrent validity of the defense and veterans pain rating scale in VA outpatients. Pain Med 16:2152–2161CrossRefPubMed Nassif TH, Hull A, Holliday SB, Sullivan P, Sandbrink F (2015) Concurrent validity of the defense and veterans pain rating scale in VA outpatients. Pain Med 16:2152–2161CrossRefPubMed
20.
Zurück zum Zitat Okoroha KR, Keller RA, Marshall NE, Jung EK, Mehran N, Owashi E et al (2016) Liposomal bupivacaine versus femoral nerve block for pain control after anterior cruciate ligament reconstruction: a prospective randomized trial. Arthroscopy 32:1838–1845CrossRefPubMed Okoroha KR, Keller RA, Marshall NE, Jung EK, Mehran N, Owashi E et al (2016) Liposomal bupivacaine versus femoral nerve block for pain control after anterior cruciate ligament reconstruction: a prospective randomized trial. Arthroscopy 32:1838–1845CrossRefPubMed
21.
Zurück zum Zitat Polomano RC, Galloway KT, Kent ML, Brandon-Edwards H, Kwon KN, Morales C et al (2016) Psychometric testing of the defense and veterans pain rating scale (DVPRS): a new pain scale for military population. Pain Med 17:1505–1519CrossRefPubMed Polomano RC, Galloway KT, Kent ML, Brandon-Edwards H, Kwon KN, Morales C et al (2016) Psychometric testing of the defense and veterans pain rating scale (DVPRS): a new pain scale for military population. Pain Med 17:1505–1519CrossRefPubMed
22.
Zurück zum Zitat Potter MQ, Sun GS, Fraser JA, Beckmann JT, Swenson JD, Maak TG et al (2014) Psychological distress in hip arthroscopy patients affects postoperative pain control. Arthroscopy 30:195–201CrossRefPubMed Potter MQ, Sun GS, Fraser JA, Beckmann JT, Swenson JD, Maak TG et al (2014) Psychological distress in hip arthroscopy patients affects postoperative pain control. Arthroscopy 30:195–201CrossRefPubMed
23.
Zurück zum Zitat Richard BM, Newton P, Ott LR, Haan D, Brubaker AN, Cole PI et al. (2012) The safety of EXPAREL (R) (bupivacaine liposome injectable suspension) administered by peripheral nerve block in rabbits and dogs. J Drug Deliv 2012:962101CrossRefPubMedPubMedCentral Richard BM, Newton P, Ott LR, Haan D, Brubaker AN, Cole PI et al. (2012) The safety of EXPAREL (R) (bupivacaine liposome injectable suspension) administered by peripheral nerve block in rabbits and dogs. J Drug Deliv 2012:962101CrossRefPubMedPubMedCentral
24.
Zurück zum Zitat Robbins J, Green CL, Parekh SG (2015) Liposomal bupivacaine in forefoot surgery. Foot Ankle Int 36:503–507CrossRefPubMed Robbins J, Green CL, Parekh SG (2015) Liposomal bupivacaine in forefoot surgery. Foot Ankle Int 36:503–507CrossRefPubMed
25.
Zurück zum Zitat Viscusi ER, Sinatra R, Onel E, Ramamoorthy SL (2014) The safety of liposome bupivacaine, a novel local analgesic formulation. Clin J Pain 30:102–110PubMed Viscusi ER, Sinatra R, Onel E, Ramamoorthy SL (2014) The safety of liposome bupivacaine, a novel local analgesic formulation. Clin J Pain 30:102–110PubMed
26.
Zurück zum Zitat YaDeau JT, Tedore T, Goytizolo EA, Kim DH, Green DS, Westrick A et al (2012) Lumbar plexus blockade reduces pain after hip arthroscopy: a prospective randomized controlled trial. Anesth Analg 115:968–972CrossRefPubMed YaDeau JT, Tedore T, Goytizolo EA, Kim DH, Green DS, Westrick A et al (2012) Lumbar plexus blockade reduces pain after hip arthroscopy: a prospective randomized controlled trial. Anesth Analg 115:968–972CrossRefPubMed
Metadaten
Titel
Fascia iliaca blockade with the addition of liposomal bupivacaine vs. plain bupivacaine for perioperative pain management following hip arthroscopy
verfasst von
Richard L. Purcell
Kyle E. Nappo
Daniel W. Griffin
Michael McCabe
Terrence Anderson
Michael Kent
Publikationsdatum
16.02.2018
Verlag
Springer Berlin Heidelberg
Erschienen in
Knee Surgery, Sports Traumatology, Arthroscopy / Ausgabe 8/2018
Print ISSN: 0942-2056
Elektronische ISSN: 1433-7347
DOI
https://doi.org/10.1007/s00167-018-4874-x

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