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Erschienen in: Aesthetic Plastic Surgery 6/2016

Open Access 11.08.2016 | Original Article

Fat Grafting with Tissue Liquefaction Technology as an Adjunct to Breast Reconstruction

verfasst von: Utku Dolen, Justin B. Cohen, Bo Overschmidt, Marissa M. Tenenbaum, Terence M. Myckatyn

Erschienen in: Aesthetic Plastic Surgery | Ausgabe 6/2016

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Abstract

Background

Tissue liquefaction technology (TLT) delivers warmed saline from the liposuction cannula tip at low pressure pulses to disaggregate adipocytes. This technology differs significantly from that used in other liposuction devices including water jet-assisted liposuction. Here we introduce our early experience with this technology in the setting of fat transfer for revision breast reconstruction.

Methods

A retrospective chart review of 136 consecutive patients who underwent fat harvest with TLT and subsequent transfer into 237 breast reconstructions was conducted at a single institution. This two-surgeon series examined donor and recipient site complication rates over a median follow-up of 143 days [87–233].

Results

The overall complication rate was 28.7 %, of which the majority (22.1 %) was fat necrosis at the recipient site as documented by any clinical, imaging, or pathologic evidence. The abdomen served as the donor site for half of the cases. Donor site complications were limited to widespread ecchymosis of the donor site notable in 10.4 % of cases. Twenty-five percent of patients had received postmastectomy radiotherapy prior to fat transfer. Prior to revision with fat transfer, implant-based breast reconstruction was used in 75.5 % of cases, and autologous flaps in the remainder. Fat transfer was combined with other reconstructive procedures 94.1 % of the time.

Conclusions

TLT can be used to harvest adipocytes for fat transfer with donor site morbidity and recipient site complications comparable to other modalities. The efficiency and quality of harvested fat makes this technology appealing for wide spread adoption during fat transfer.

Level of Evidence IV

This journal requires that the authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.​springer.​com/​00266.
Literatur
1.
Zurück zum Zitat Agnelli G, Bolis G, Capussotti L, Scarpa RM, Tonelli F, Bonizzoni E, Moia M, Parazzini F, Rossi R, Sonaglia F, Valarani B, Bianchini C, Gussoni G (2006) A clinical outcome-based prospective study on venous thromboembolism after cancer surgery: the @RISTOS project. Ann Surg 243(1):89–95CrossRefPubMedPubMedCentral Agnelli G, Bolis G, Capussotti L, Scarpa RM, Tonelli F, Bonizzoni E, Moia M, Parazzini F, Rossi R, Sonaglia F, Valarani B, Bianchini C, Gussoni G (2006) A clinical outcome-based prospective study on venous thromboembolism after cancer surgery: the @RISTOS project. Ann Surg 243(1):89–95CrossRefPubMedPubMedCentral
2.
Zurück zum Zitat Ahmad J, Eaves FF 3rd, Rohrich RJ, Kenkel JM (2011) The American Society for Aesthetic Plastic Surgery (ASAPS) survey: current trends in liposuction. Aesthet Surg J 31(2):214–224CrossRefPubMed Ahmad J, Eaves FF 3rd, Rohrich RJ, Kenkel JM (2011) The American Society for Aesthetic Plastic Surgery (ASAPS) survey: current trends in liposuction. Aesthet Surg J 31(2):214–224CrossRefPubMed
3.
Zurück zum Zitat Albin R, de Campo T (1999) Large-volume liposuction in 181 patients. Aesthet Plast Surg 23(1):5–15CrossRef Albin R, de Campo T (1999) Large-volume liposuction in 181 patients. Aesthet Plast Surg 23(1):5–15CrossRef
4.
Zurück zum Zitat Aly AS, Cram AE, Chao M, Pang J, McKeon M (2003) Belt lipectomy for circumferential truncal excess: the university of iowa experience. Plast Reconstr Surg 111(1):398–413CrossRefPubMed Aly AS, Cram AE, Chao M, Pang J, McKeon M (2003) Belt lipectomy for circumferential truncal excess: the university of iowa experience. Plast Reconstr Surg 111(1):398–413CrossRefPubMed
6.
Zurück zum Zitat Commons GW, Halperin B, Chang CC (2001) Large-volume liposuction: a review of 631 consecutive cases over 12 years. Plast Reconstr Surg 108(6):1753–1763CrossRefPubMed Commons GW, Halperin B, Chang CC (2001) Large-volume liposuction: a review of 631 consecutive cases over 12 years. Plast Reconstr Surg 108(6):1753–1763CrossRefPubMed
7.
Zurück zum Zitat Costantini M, Cipriani A, Belli P, Bufi E, Fubelli R, Visconti G, Salgarello M, Bonomo L (2013) Radiological findings in mammary autologous fat injections: a multi-technique evaluation. Clin Radiol 68(1):27–33CrossRefPubMed Costantini M, Cipriani A, Belli P, Bufi E, Fubelli R, Visconti G, Salgarello M, Bonomo L (2013) Radiological findings in mammary autologous fat injections: a multi-technique evaluation. Clin Radiol 68(1):27–33CrossRefPubMed
8.
Zurück zum Zitat Crawford JL, Hubbard BA, Colbert SH, Puckett CL (2010) Fine tuning lipoaspirate viability for fat grafting. Plast Reconstr Surg 126(4):1342–1348CrossRefPubMed Crawford JL, Hubbard BA, Colbert SH, Puckett CL (2010) Fine tuning lipoaspirate viability for fat grafting. Plast Reconstr Surg 126(4):1342–1348CrossRefPubMed
9.
Zurück zum Zitat Davis K, Rasko Y, Oni G, Bills J, Geissler P, Kenkel JM (2013) Comparison of adipocyte viability and fat graft survival in an animal model using a new tissue liquefaction liposuction device vs standard coleman method for harvesting. Aesthet Surg J 33(8):1175–1185CrossRefPubMed Davis K, Rasko Y, Oni G, Bills J, Geissler P, Kenkel JM (2013) Comparison of adipocyte viability and fat graft survival in an animal model using a new tissue liquefaction liposuction device vs standard coleman method for harvesting. Aesthet Surg J 33(8):1175–1185CrossRefPubMed
10.
Zurück zum Zitat Direkze NC, Jeffery R, Hodivala-Dilke K, Hunt T, Playford RJ, Elia G, Poulsom R, Wright NA, Alison MR (2006) Bone marrow-derived stromal cells express lineage-related messenger RNA species. Cancer Res 66(3):1265–1269CrossRefPubMed Direkze NC, Jeffery R, Hodivala-Dilke K, Hunt T, Playford RJ, Elia G, Poulsom R, Wright NA, Alison MR (2006) Bone marrow-derived stromal cells express lineage-related messenger RNA species. Cancer Res 66(3):1265–1269CrossRefPubMed
11.
Zurück zum Zitat Duscher D, Atashroo D, Maan ZN, Luan A, Brett EA, Barrera J, Khong SM, Zielins ER, Whittam AJ, Hu MS, Walmsley GG, Pollhammer MS, Schmidt M, Schilling AF, Machens HG, Huemer GM, Wan DC, Longaker MT, Gurtner GC (2016) Ultrasound-assisted liposuction does not compromise the regenerative potential of adipose-derived stem cells. Stem Cells Transl Med 5(2):248–257CrossRefPubMed Duscher D, Atashroo D, Maan ZN, Luan A, Brett EA, Barrera J, Khong SM, Zielins ER, Whittam AJ, Hu MS, Walmsley GG, Pollhammer MS, Schmidt M, Schilling AF, Machens HG, Huemer GM, Wan DC, Longaker MT, Gurtner GC (2016) Ultrasound-assisted liposuction does not compromise the regenerative potential of adipose-derived stem cells. Stem Cells Transl Med 5(2):248–257CrossRefPubMed
12.
Zurück zum Zitat Duscher D, Luan A, Rennert RC, Atashroo D, Maan ZN, Brett EA, Whittam AJ, Ho N, Lin M, Hu MS, Walmsley GG, Wenny R, Schmidt M, Schilling AF, Machens HG, Huemer GM, Wan DC, Longaker MT, Gurtner GC (2016) Suction assisted liposuction does not impair the regenerative potential of adipose derived stem cells. J Transl Med 14(1):126CrossRefPubMedPubMedCentral Duscher D, Luan A, Rennert RC, Atashroo D, Maan ZN, Brett EA, Whittam AJ, Ho N, Lin M, Hu MS, Walmsley GG, Wenny R, Schmidt M, Schilling AF, Machens HG, Huemer GM, Wan DC, Longaker MT, Gurtner GC (2016) Suction assisted liposuction does not impair the regenerative potential of adipose derived stem cells. J Transl Med 14(1):126CrossRefPubMedPubMedCentral
13.
Zurück zum Zitat Erdim M, Tezel E, Numanoglu A, Sav A (2009) The effects of the size of liposuction cannula on adipocyte survival and the optimum temperature for fat graft storage: an experimental study. J Plast Reconstr Aesthet Surg 62(9):1210–1214CrossRefPubMed Erdim M, Tezel E, Numanoglu A, Sav A (2009) The effects of the size of liposuction cannula on adipocyte survival and the optimum temperature for fat graft storage: an experimental study. J Plast Reconstr Aesthet Surg 62(9):1210–1214CrossRefPubMed
14.
Zurück zum Zitat Fabi SG, Goldman MP (2012) Hand rejuvenation: a review and our experience. Dermatol Surg 38(7 Pt 2):1112–1127CrossRefPubMed Fabi SG, Goldman MP (2012) Hand rejuvenation: a review and our experience. Dermatol Surg 38(7 Pt 2):1112–1127CrossRefPubMed
15.
Zurück zum Zitat Fulton JE Jr, Rahimi AD, Helton P, Watson T, Dahlberg K (2000) Lip rejuvenation. Dermatol Surg 26(5):470–474CrossRefPubMed Fulton JE Jr, Rahimi AD, Helton P, Watson T, Dahlberg K (2000) Lip rejuvenation. Dermatol Surg 26(5):470–474CrossRefPubMed
16.
Zurück zum Zitat Gale KL, Rakha EA, Ball G, Tan VK, McCulley SJ, Macmillan RD (2015) A case-controlled study of the oncologic safety of fat grafting. Plast Reconstr Surg 135(5):1263–1275CrossRefPubMed Gale KL, Rakha EA, Ball G, Tan VK, McCulley SJ, Macmillan RD (2015) A case-controlled study of the oncologic safety of fat grafting. Plast Reconstr Surg 135(5):1263–1275CrossRefPubMed
17.
Zurück zum Zitat Girard AC, Atlan M, Bencharif K, Gunasekaran MK, Delarue P, Hulard O, Lefebvre-d’Hellencourt C, Roche R, Hoareau L, Festy F (2013) New insights into lidocaine and adrenaline effects on human adipose stem cells. Aesthet Plast Surg 37(1):144–152CrossRef Girard AC, Atlan M, Bencharif K, Gunasekaran MK, Delarue P, Hulard O, Lefebvre-d’Hellencourt C, Roche R, Hoareau L, Festy F (2013) New insights into lidocaine and adrenaline effects on human adipose stem cells. Aesthet Plast Surg 37(1):144–152CrossRef
18.
Zurück zum Zitat Gosset J, Guerin N, Toussoun G, Delaporte T, Delay E (2008) Radiological evaluation after lipomodelling for correction of breast conservative treatment sequelae. Ann Chir Plast Esthet 53(2):178–189CrossRefPubMed Gosset J, Guerin N, Toussoun G, Delaporte T, Delay E (2008) Radiological evaluation after lipomodelling for correction of breast conservative treatment sequelae. Ann Chir Plast Esthet 53(2):178–189CrossRefPubMed
19.
Zurück zum Zitat Grazer FM, de Jong RH (2000) Fatal outcomes from liposuction: census survey of cosmetic surgeons. Plast Reconstr Surg 105(1):436–446CrossRefPubMed Grazer FM, de Jong RH (2000) Fatal outcomes from liposuction: census survey of cosmetic surgeons. Plast Reconstr Surg 105(1):436–446CrossRefPubMed
20.
Zurück zum Zitat Harrison BL, Malafa M, Davis K, Rohrich RJ (2015) The discordant histology of grafted fat: a systematic review of the literature. Plast Reconstr Surg 135(3):542e–555eCrossRefPubMed Harrison BL, Malafa M, Davis K, Rohrich RJ (2015) The discordant histology of grafted fat: a systematic review of the literature. Plast Reconstr Surg 135(3):542e–555eCrossRefPubMed
21.
Zurück zum Zitat Hester TR Jr, Baird W, Bostwick J 3rd, Nahai F, Cukic J (1989) Abdominoplasty combined with other major surgical procedures: safe or sorry? Plast Reconstr Surg 83(6):997–1004CrossRefPubMed Hester TR Jr, Baird W, Bostwick J 3rd, Nahai F, Cukic J (1989) Abdominoplasty combined with other major surgical procedures: safe or sorry? Plast Reconstr Surg 83(6):997–1004CrossRefPubMed
22.
Zurück zum Zitat Hivernaud V, Lefourn B, Guicheux J, Weiss P, Festy F, Girard AC, Roche R (2015) Autologous fat grafting in the breast: critical points and technique improvements. Aesthet Plast Surg 39(4):547–561CrossRef Hivernaud V, Lefourn B, Guicheux J, Weiss P, Festy F, Girard AC, Roche R (2015) Autologous fat grafting in the breast: critical points and technique improvements. Aesthet Plast Surg 39(4):547–561CrossRef
23.
Zurück zum Zitat Iyengar P, Espina V, Williams TW, Lin Y, Berry D, Jelicks LA, Lee H, Temple K, Graves R, Pollard J, Chopra N, Russell RG, Sasisekharan R, Trock BJ, Lippman M, Calvert VS, Petricoin EF 3rd, Liotta L, Dadachova E, Pestell RG, Lisanti MP, Bonaldo P, Scherer PE (2005) Adipocyte-derived collagen VI affects early mammary tumor progression in vivo, demonstrating a critical interaction in the tumor/stroma microenvironment. J Clin Invest 115(5):1163–1176CrossRefPubMedPubMedCentral Iyengar P, Espina V, Williams TW, Lin Y, Berry D, Jelicks LA, Lee H, Temple K, Graves R, Pollard J, Chopra N, Russell RG, Sasisekharan R, Trock BJ, Lippman M, Calvert VS, Petricoin EF 3rd, Liotta L, Dadachova E, Pestell RG, Lisanti MP, Bonaldo P, Scherer PE (2005) Adipocyte-derived collagen VI affects early mammary tumor progression in vivo, demonstrating a critical interaction in the tumor/stroma microenvironment. J Clin Invest 115(5):1163–1176CrossRefPubMedPubMedCentral
24.
Zurück zum Zitat Keck M, Kober J, Riedl O, Kitzinger HB, Wolf S, Stulnig TM, Zeyda M, Gugerell A (2014) Power assisted liposuction to obtain adipose-derived stem cells: impact on viability and differentiation to adipocytes in comparison to manual aspiration. J Plast Reconstr Aesthet Surg 67(1):e1–e8CrossRefPubMed Keck M, Kober J, Riedl O, Kitzinger HB, Wolf S, Stulnig TM, Zeyda M, Gugerell A (2014) Power assisted liposuction to obtain adipose-derived stem cells: impact on viability and differentiation to adipocytes in comparison to manual aspiration. J Plast Reconstr Aesthet Surg 67(1):e1–e8CrossRefPubMed
25.
Zurück zum Zitat Keck M, Zeyda M, Gollinger K, Burjak S, Kamolz LP, Frey M, Stulnig TM (2010) Local anesthetics have a major impact on viability of preadipocytes and their differentiation into adipocytes. Plast Reconstr Surg 126(5):1500–1505CrossRefPubMed Keck M, Zeyda M, Gollinger K, Burjak S, Kamolz LP, Frey M, Stulnig TM (2010) Local anesthetics have a major impact on viability of preadipocytes and their differentiation into adipocytes. Plast Reconstr Surg 126(5):1500–1505CrossRefPubMed
26.
Zurück zum Zitat Khouri RK, Rigotti G, Cardoso E, Khouri RK Jr, Biggs TM (2014) Megavolume autologous fat transfer: part I theory and principles. Plast Reconstr Surg 133(3):550–557CrossRefPubMed Khouri RK, Rigotti G, Cardoso E, Khouri RK Jr, Biggs TM (2014) Megavolume autologous fat transfer: part I theory and principles. Plast Reconstr Surg 133(3):550–557CrossRefPubMed
27.
Zurück zum Zitat Khouri RK, Rigotti G, Cardoso E, Khouri RK Jr, Biggs TM (2014) Megavolume autologous fat transfer: part II Practice and techniques. Plast Reconstr Surg 133(6):1369–1377CrossRefPubMed Khouri RK, Rigotti G, Cardoso E, Khouri RK Jr, Biggs TM (2014) Megavolume autologous fat transfer: part II Practice and techniques. Plast Reconstr Surg 133(6):1369–1377CrossRefPubMed
28.
Zurück zum Zitat Khouri RK, Smit JM, Cardoso E, Pallua N, Lantieri L, Mathijssen IM, Khouri RK Jr, Rigotti G (2013) Percutaneous aponeurotomy and lipofilling: a regenerative alternative to flap reconstruction? Plast Reconstr Surg 132(5):1280–1290CrossRefPubMed Khouri RK, Smit JM, Cardoso E, Pallua N, Lantieri L, Mathijssen IM, Khouri RK Jr, Rigotti G (2013) Percutaneous aponeurotomy and lipofilling: a regenerative alternative to flap reconstruction? Plast Reconstr Surg 132(5):1280–1290CrossRefPubMed
29.
Zurück zum Zitat Kling RE, Mehrara BJ, Pusic AL, Young VL, Hume KM, Crotty CA, Rubin JP (2013) Trends in autologous fat grafting to the breast: a national survey of the american society of plastic surgeons. Plast Reconstr Surg 132(1):35–46CrossRefPubMed Kling RE, Mehrara BJ, Pusic AL, Young VL, Hume KM, Crotty CA, Rubin JP (2013) Trends in autologous fat grafting to the breast: a national survey of the american society of plastic surgeons. Plast Reconstr Surg 132(1):35–46CrossRefPubMed
30.
Zurück zum Zitat Klinger M, Caviggioli F, Klinger FM, Giannasi S, Bandi V, Banzatti B, Forcellini D, Maione L, Catania B, Vinci V (2013) Autologous fat graft in scar treatment. J Craniofac Surg 24(5):1610–1615CrossRefPubMed Klinger M, Caviggioli F, Klinger FM, Giannasi S, Bandi V, Banzatti B, Forcellini D, Maione L, Catania B, Vinci V (2013) Autologous fat graft in scar treatment. J Craniofac Surg 24(5):1610–1615CrossRefPubMed
31.
Zurück zum Zitat Largo RD, Tchang LA, Mele V, Scherberich A, Harder Y, Wettstein R, Schaefer DJ (2014) Efficacy, safety and complications of autologous fat grafting to healthy breast tissue: a systematic review. J Plast Reconstr Aesthet Surg 67(4):437–448CrossRefPubMed Largo RD, Tchang LA, Mele V, Scherberich A, Harder Y, Wettstein R, Schaefer DJ (2014) Efficacy, safety and complications of autologous fat grafting to healthy breast tissue: a systematic review. J Plast Reconstr Aesthet Surg 67(4):437–448CrossRefPubMed
32.
Zurück zum Zitat Lohsiriwat V, Curigliano G, Rietjens M, Goldhirsch A, Petit JY (2011) Autologous fat transplantation in patients with breast cancer: “silencing” or “fueling” cancer recurrence? Breast 20(4):351–357CrossRefPubMed Lohsiriwat V, Curigliano G, Rietjens M, Goldhirsch A, Petit JY (2011) Autologous fat transplantation in patients with breast cancer: “silencing” or “fueling” cancer recurrence? Breast 20(4):351–357CrossRefPubMed
33.
Zurück zum Zitat Manabe Y, Toda S, Miyazaki K, Sugihara H (2003) Mature adipocytes, but not preadipocytes, promote the growth of breast carcinoma cells in collagen gel matrix culture through cancer—stromal cell interactions. J Pathol 201(2):221–228CrossRefPubMed Manabe Y, Toda S, Miyazaki K, Sugihara H (2003) Mature adipocytes, but not preadipocytes, promote the growth of breast carcinoma cells in collagen gel matrix culture through cancer—stromal cell interactions. J Pathol 201(2):221–228CrossRefPubMed
34.
Zurück zum Zitat Martin-Padura I, Gregato G, Marighetti P, Mancuso P, Calleri A, Corsini C, Pruneri G, Manzotti M, Lohsiriwat V, Rietjens M, Petit JY, Bertolini F (2012) The white adipose tissue used in lipotransfer procedures is a rich reservoir of CD34+ progenitors able to promote cancer progression. Cancer Res 72(1):325–334CrossRefPubMed Martin-Padura I, Gregato G, Marighetti P, Mancuso P, Calleri A, Corsini C, Pruneri G, Manzotti M, Lohsiriwat V, Rietjens M, Petit JY, Bertolini F (2012) The white adipose tissue used in lipotransfer procedures is a rich reservoir of CD34+ progenitors able to promote cancer progression. Cancer Res 72(1):325–334CrossRefPubMed
35.
Zurück zum Zitat Meyer J, Salamon A, Herzmann N, Adam S, Kleine HD, Matthiesen I, Ueberreiter K, Peters K (2015) Isolation and differentiation potential of human mesenchymal stem cells from adipose tissue harvested by water jet-assisted liposuction. Aesthet Surg J 35(8):1030–1039CrossRefPubMed Meyer J, Salamon A, Herzmann N, Adam S, Kleine HD, Matthiesen I, Ueberreiter K, Peters K (2015) Isolation and differentiation potential of human mesenchymal stem cells from adipose tissue harvested by water jet-assisted liposuction. Aesthet Surg J 35(8):1030–1039CrossRefPubMed
36.
Zurück zum Zitat Nwaogu I, Yan Y, Margenthaler JA, Myckatyn TM (2015) Venous thromboembolism after breast reconstruction in patients undergoing breast surgery: an american college of surgeons NSQIP analysis. J Am Coll Surg 220(5):886–893CrossRefPubMed Nwaogu I, Yan Y, Margenthaler JA, Myckatyn TM (2015) Venous thromboembolism after breast reconstruction in patients undergoing breast surgery: an american college of surgeons NSQIP analysis. J Am Coll Surg 220(5):886–893CrossRefPubMed
37.
Zurück zum Zitat Orecchioni S, Gregato G, Martin-Padura I, Reggiani F, Braidotti P, Mancuso P, Calleri A, Quarna J, Marighetti P, Aldeni C, Pruneri G, Martella S, Manconi A, Petit JY, Rietjens M, Bertolini F (2013) Complementary populations of human adipose CD34+ progenitor cells promote growth, angiogenesis, and metastasis of breast cancer. Cancer Res 73(19):5880–5891CrossRefPubMed Orecchioni S, Gregato G, Martin-Padura I, Reggiani F, Braidotti P, Mancuso P, Calleri A, Quarna J, Marighetti P, Aldeni C, Pruneri G, Martella S, Manconi A, Petit JY, Rietjens M, Bertolini F (2013) Complementary populations of human adipose CD34+ progenitor cells promote growth, angiogenesis, and metastasis of breast cancer. Cancer Res 73(19):5880–5891CrossRefPubMed
38.
Zurück zum Zitat Ozsoy Z, Kul Z, Bilir A (2006) The role of cannula diameter in improved adipocyte viability: a quantitative analysis. Aesthet Surg J 26(3):287–289CrossRefPubMed Ozsoy Z, Kul Z, Bilir A (2006) The role of cannula diameter in improved adipocyte viability: a quantitative analysis. Aesthet Surg J 26(3):287–289CrossRefPubMed
39.
Zurück zum Zitat Padoin AV, Braga-Silva J, Martins P, Rezende K, Rezende AR, Grechi B, Gehlen D, Machado DC (2008) Sources of processed lipoaspirate cells: influence of donor site on cell concentration. Plast Reconstr Surg 122(2):614–618CrossRefPubMed Padoin AV, Braga-Silva J, Martins P, Rezende K, Rezende AR, Grechi B, Gehlen D, Machado DC (2008) Sources of processed lipoaspirate cells: influence of donor site on cell concentration. Plast Reconstr Surg 122(2):614–618CrossRefPubMed
40.
Zurück zum Zitat Panetta NJ, Gupta DM, Kwan MD, Wan DC, Commons GW, Longaker MT (2009) Tissue harvest by means of suction-assisted or third-generation ultrasound-assisted lipoaspiration has no effect on osteogenic potential of human adipose-derived stromal cells. Plast Reconstr Surg 124(1):65–73CrossRefPubMed Panetta NJ, Gupta DM, Kwan MD, Wan DC, Commons GW, Longaker MT (2009) Tissue harvest by means of suction-assisted or third-generation ultrasound-assisted lipoaspiration has no effect on osteogenic potential of human adipose-derived stromal cells. Plast Reconstr Surg 124(1):65–73CrossRefPubMed
41.
Zurück zum Zitat Panfilov DE (2006) Augmentative phalloplasty. Aesthet Plast Surg 30(2):183–197CrossRef Panfilov DE (2006) Augmentative phalloplasty. Aesthet Plast Surg 30(2):183–197CrossRef
42.
Zurück zum Zitat Petit JY, Botteri E, Lohsiriwat V, Rietjens M, De Lorenzi F, Garusi C, Rossetto F, Martella S, Manconi A, Bertolini F, Curigliano G, Veronesi P, Santillo B, Rotmensz N (2012) Locoregional recurrence risk after lipofilling in breast cancer patients. Ann Oncol 23(3):582–588CrossRefPubMed Petit JY, Botteri E, Lohsiriwat V, Rietjens M, De Lorenzi F, Garusi C, Rossetto F, Martella S, Manconi A, Bertolini F, Curigliano G, Veronesi P, Santillo B, Rotmensz N (2012) Locoregional recurrence risk after lipofilling in breast cancer patients. Ann Oncol 23(3):582–588CrossRefPubMed
43.
Zurück zum Zitat Petit JY, Lohsiriwat V, Clough KB, Sarfati I, Ihrai T, Rietjens M, Veronesi P, Rossetto F, Scevola A, Delay E (2011) The oncologic outcome and immediate surgical complications of lipofilling in breast cancer patients: a multicenter study-milan-paris-lyon experience of 646 lipofilling procedures. Plast Reconstr Surg 128(2):341–346CrossRefPubMed Petit JY, Lohsiriwat V, Clough KB, Sarfati I, Ihrai T, Rietjens M, Veronesi P, Rossetto F, Scevola A, Delay E (2011) The oncologic outcome and immediate surgical complications of lipofilling in breast cancer patients: a multicenter study-milan-paris-lyon experience of 646 lipofilling procedures. Plast Reconstr Surg 128(2):341–346CrossRefPubMed
44.
Zurück zum Zitat Petit JY, Rietjens M, Botteri E, Rotmensz N, Bertolini F, Curigliano G, Rey P, Garusi C, De Lorenzi F, Martella S, Manconi A, Barbieri B, Veronesi P, Intra M, Brambullo T, Gottardi A, Sommario M, Lomeo G, Iera M, Giovinazzo V, Lohsiriwat V (2013) Evaluation of fat grafting safety in patients with intraepithelial neoplasia: a matched-cohort study. Ann Oncol 24(6):1479–1484CrossRefPubMed Petit JY, Rietjens M, Botteri E, Rotmensz N, Bertolini F, Curigliano G, Rey P, Garusi C, De Lorenzi F, Martella S, Manconi A, Barbieri B, Veronesi P, Intra M, Brambullo T, Gottardi A, Sommario M, Lomeo G, Iera M, Giovinazzo V, Lohsiriwat V (2013) Evaluation of fat grafting safety in patients with intraepithelial neoplasia: a matched-cohort study. Ann Oncol 24(6):1479–1484CrossRefPubMed
45.
Zurück zum Zitat Prado A, Andrades P, Danilla S, Leniz P, Castillo P, Gaete F (2006) A prospective, randomized, double-blind, controlled clinical trial comparing laser-assisted lipoplasty with suction-assisted lipoplasty. Plast Reconstr Surg 118(4):1032–1045CrossRefPubMed Prado A, Andrades P, Danilla S, Leniz P, Castillo P, Gaete F (2006) A prospective, randomized, double-blind, controlled clinical trial comparing laser-assisted lipoplasty with suction-assisted lipoplasty. Plast Reconstr Surg 118(4):1032–1045CrossRefPubMed
46.
Zurück zum Zitat Sasaki GH (2011) Water-assisted liposuction for body contouring and lipoharvesting: safety and efficacy in 41 consecutive patients. Aesthet Surg J 31(1):76–88CrossRefPubMed Sasaki GH (2011) Water-assisted liposuction for body contouring and lipoharvesting: safety and efficacy in 41 consecutive patients. Aesthet Surg J 31(1):76–88CrossRefPubMed
47.
Zurück zum Zitat Schafer ME, Hicok KC, Mills DC, Cohen SR, Chao JJ (2013) Acute adipocyte viability after third-generation ultrasound-assisted liposuction. Aesthet Surg J 33(5):698–704CrossRefPubMed Schafer ME, Hicok KC, Mills DC, Cohen SR, Chao JJ (2013) Acute adipocyte viability after third-generation ultrasound-assisted liposuction. Aesthet Surg J 33(5):698–704CrossRefPubMed
48.
Zurück zum Zitat Schaffler A, Scholmerich J, Buechler C (2007) Mechanisms of disease: adipokines and breast cancer—endocrine and paracrine mechanisms that connect adiposity and breast cancer. Nat Clin Pract Endocrinol Metab 3(4):345–354CrossRefPubMed Schaffler A, Scholmerich J, Buechler C (2007) Mechanisms of disease: adipokines and breast cancer—endocrine and paracrine mechanisms that connect adiposity and breast cancer. Nat Clin Pract Endocrinol Metab 3(4):345–354CrossRefPubMed
49.
Zurück zum Zitat Shiffman MA, Mirrafati S (2001) Fat transfer techniques: the effect of harvest and transfer methods on adipocyte viability and review of the literature. Dermatol Surg 27(9):819–826PubMed Shiffman MA, Mirrafati S (2001) Fat transfer techniques: the effect of harvest and transfer methods on adipocyte viability and review of the literature. Dermatol Surg 27(9):819–826PubMed
50.
Zurück zum Zitat Sinno S, Mehta K, Reavey PL, Simmons C, Stuzin JM (2015) Current trends in facial rejuvenation: an assessment of asps members’ use of fat grafting during face lifting. Plast Reconstr Surg 136(1):20e–30eCrossRefPubMed Sinno S, Mehta K, Reavey PL, Simmons C, Stuzin JM (2015) Current trends in facial rejuvenation: an assessment of asps members’ use of fat grafting during face lifting. Plast Reconstr Surg 136(1):20e–30eCrossRefPubMed
51.
Zurück zum Zitat Stephan PJ, Kenkel JM (2010) Updates and advances in liposuction. Aesthet Surg J 30(1):83–97CrossRefPubMed Stephan PJ, Kenkel JM (2010) Updates and advances in liposuction. Aesthet Surg J 30(1):83–97CrossRefPubMed
52.
Zurück zum Zitat Strong AL, Cederna PS, Rubin JP, Coleman SR, Levi B (2015) The current state of fat grafting: a review of harvesting, processing, and injection techniques. Plast Reconstr Surg 136(4):897–912CrossRefPubMedPubMedCentral Strong AL, Cederna PS, Rubin JP, Coleman SR, Levi B (2015) The current state of fat grafting: a review of harvesting, processing, and injection techniques. Plast Reconstr Surg 136(4):897–912CrossRefPubMedPubMedCentral
53.
Zurück zum Zitat Sultan SM, Stern CS, Allen RJ Jr, Thanik VD, Chang CC, Nguyen PD, Canizares O, Szpalski C, Saadeh PB, Warren SM, Coleman SR, Hazen A (2011) Human fat grafting alleviates radiation skin damage in a murine model. Plast Reconstr Surg 128(2):363–372CrossRefPubMed Sultan SM, Stern CS, Allen RJ Jr, Thanik VD, Chang CC, Nguyen PD, Canizares O, Szpalski C, Saadeh PB, Warren SM, Coleman SR, Hazen A (2011) Human fat grafting alleviates radiation skin damage in a murine model. Plast Reconstr Surg 128(2):363–372CrossRefPubMed
54.
Zurück zum Zitat Surgeons A. S. o. P. (2013).2012 Plastic surgery statistics report ASPS national clearinghouse of plastic surgery procedural statistics Surgeons A. S. o. P. (2013).2012 Plastic surgery statistics report ASPS national clearinghouse of plastic surgery procedural statistics
55.
Zurück zum Zitat Toledo LS (2015) Gluteal augmentation with fat grafting: The Brazilian Buttock technique: 30 years’ experience. Clin Plast Surg 42(2):253–261CrossRefPubMed Toledo LS (2015) Gluteal augmentation with fat grafting: The Brazilian Buttock technique: 30 years’ experience. Clin Plast Surg 42(2):253–261CrossRefPubMed
56.
Zurück zum Zitat Ullmann Y, Shoshani O, Fodor A, Ramon Y, Carmi N, Eldor L, Gilhar A (2005) Searching for the favorable donor site for fat injection: in vivo study using the nude mice model. Dermatol Surg 31(10):1304–1307CrossRefPubMed Ullmann Y, Shoshani O, Fodor A, Ramon Y, Carmi N, Eldor L, Gilhar A (2005) Searching for the favorable donor site for fat injection: in vivo study using the nude mice model. Dermatol Surg 31(10):1304–1307CrossRefPubMed
57.
Zurück zum Zitat Veber M, Tourasse C, Toussoun G, Moutran M, Mojallal A, Delay E (2011) Radiographic findings after breast augmentation by autologous fat transfer. Plast Reconstr Surg 127(3):1289–1299CrossRefPubMed Veber M, Tourasse C, Toussoun G, Moutran M, Mojallal A, Delay E (2011) Radiographic findings after breast augmentation by autologous fat transfer. Plast Reconstr Surg 127(3):1289–1299CrossRefPubMed
58.
Zurück zum Zitat Voss SC, Sharp HC, Scott JR (1986) Abdominoplasty combined with gynecologic surgical procedures. Obstet Gynecol 67(2):181–185CrossRefPubMed Voss SC, Sharp HC, Scott JR (1986) Abdominoplasty combined with gynecologic surgical procedures. Obstet Gynecol 67(2):181–185CrossRefPubMed
59.
Zurück zum Zitat Yin S, Luan J, Fu S, Wang Q, Zhuang Q (2015) Does water-jet force make a difference in fat grafting? In vitro and in vivo evidence of improved lipoaspirate viability and fat graft survival. Plast Reconstr Surg 135(1):127–138CrossRefPubMed Yin S, Luan J, Fu S, Wang Q, Zhuang Q (2015) Does water-jet force make a difference in fat grafting? In vitro and in vivo evidence of improved lipoaspirate viability and fat graft survival. Plast Reconstr Surg 135(1):127–138CrossRefPubMed
60.
Zurück zum Zitat Zhang Y, Daquinag A, Traktuev DO, Amaya-Manzanares F, Simmons PJ, March KL, Pasqualini R, Arap W, Kolonin MG (2009) White adipose tissue cells are recruited by experimental tumors and promote cancer progression in mouse models. Cancer Res 69(12):5259–5266CrossRefPubMed Zhang Y, Daquinag A, Traktuev DO, Amaya-Manzanares F, Simmons PJ, March KL, Pasqualini R, Arap W, Kolonin MG (2009) White adipose tissue cells are recruited by experimental tumors and promote cancer progression in mouse models. Cancer Res 69(12):5259–5266CrossRefPubMed
61.
Zurück zum Zitat Zimmerlin L, Donnenberg AD, Rubin JP, Basse P, Landreneau RJ, Donnenberg VS (2011) Regenerative therapy and cancer: in vitro and in vivo studies of the interaction between adipose-derived stem cells and breast cancer cells from clinical isolates. Tissue Eng Part A 17(1–2):93–106CrossRefPubMed Zimmerlin L, Donnenberg AD, Rubin JP, Basse P, Landreneau RJ, Donnenberg VS (2011) Regenerative therapy and cancer: in vitro and in vivo studies of the interaction between adipose-derived stem cells and breast cancer cells from clinical isolates. Tissue Eng Part A 17(1–2):93–106CrossRefPubMed
62.
Zurück zum Zitat Zocchi ML, Zuliani F (2008) Bicompartmental breast lipostructuring. Aesthet Plast Surg 32(2):313–328CrossRef Zocchi ML, Zuliani F (2008) Bicompartmental breast lipostructuring. Aesthet Plast Surg 32(2):313–328CrossRef
Metadaten
Titel
Fat Grafting with Tissue Liquefaction Technology as an Adjunct to Breast Reconstruction
verfasst von
Utku Dolen
Justin B. Cohen
Bo Overschmidt
Marissa M. Tenenbaum
Terence M. Myckatyn
Publikationsdatum
11.08.2016
Verlag
Springer US
Erschienen in
Aesthetic Plastic Surgery / Ausgabe 6/2016
Print ISSN: 0364-216X
Elektronische ISSN: 1432-5241
DOI
https://doi.org/10.1007/s00266-016-0690-1

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