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Erschienen in: Forensic Science, Medicine and Pathology 3/2021

04.02.2021 | Images in Forensics

Fatal bleeding after transfemoral coronary angiography in anorexia nervosa

verfasst von: Inga Duval, Elke Doberentz, Burkhard Madea

Erschienen in: Forensic Science, Medicine and Pathology | Ausgabe 3/2021

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Abstract

In 2015, 911,841 left heart catheterizations and 365,038 percutaneous coronary interventions were carried out in Germany. Complication rates for elective cardiac catheterization are low; however, the risk of complications increases with patient age and comorbidity. We present the case of a 49-year-old woman with long-term anorexia nervosa who underwent a diagnostic left heart catheterization on suspicion of takotsubo cardiomyopathy (TTC). She was found with extended hemorrhage from the puncture site approximately 3.5 h after the procedure. Autopsy identified fatal bleeding as the cause of death. Clinical examinations, autopsy findings, and forensic follow-up examinations revealed no pre-existing conditions that could have contributed to fatal bleeding. Anorexia nervosa is an eating disorder with a high mortality rate. Suicide is one of the most frequent causes of death among anorexia nervosa patients. Considering the patient’s history of psychiatric problems and previous suicidal utterances, we assume that she manipulated her pressure bandage with suicidal intent.
Literatur
1.
Zurück zum Zitat Schulz M, Iwersen-Bergmann S, Andresen H, Schmoldt A. Therapeutic and toxic blood concentrations of nearly 1,000 drugs and other xenobiotics. Crit Care. 2012;16:R136.CrossRef Schulz M, Iwersen-Bergmann S, Andresen H, Schmoldt A. Therapeutic and toxic blood concentrations of nearly 1,000 drugs and other xenobiotics. Crit Care. 2012;16:R136.CrossRef
2.
Zurück zum Zitat Lazambi I, Syed S, Reddy V, Jain R, Harbhajanka A, Arunkumar P. Myocardial changes in a patient with anorexia nervosa: A case report and review of literature. Am J Clin Pathol. 2015;143:734–7.CrossRef Lazambi I, Syed S, Reddy V, Jain R, Harbhajanka A, Arunkumar P. Myocardial changes in a patient with anorexia nervosa: A case report and review of literature. Am J Clin Pathol. 2015;143:734–7.CrossRef
3.
Zurück zum Zitat Ohwada R, Hotta M, Kimura H, Takagi S, Matsuda N, Nomura K, et al. Ampulla cardiomyopathy after hypoglycemia in three young female patients with anorexia nervosa. Intern Med. 2005;44:228–33.CrossRef Ohwada R, Hotta M, Kimura H, Takagi S, Matsuda N, Nomura K, et al. Ampulla cardiomyopathy after hypoglycemia in three young female patients with anorexia nervosa. Intern Med. 2005;44:228–33.CrossRef
4.
Zurück zum Zitat Giovinazzo S, Sukkar SG, Rosa GM, Zappi A, Bezante GP, Balbi M, et al. Anorexia nervosa and heart disease: a systematic review. Eat Weight Disord. 2019;24:199–207.CrossRef Giovinazzo S, Sukkar SG, Rosa GM, Zappi A, Bezante GP, Balbi M, et al. Anorexia nervosa and heart disease: a systematic review. Eat Weight Disord. 2019;24:199–207.CrossRef
5.
Zurück zum Zitat Cuntz U, Walter C, Zipfel S. Körperliche folgeerkrankungen von essstörungen. In: Herpertz S, Fichter M, Herpetz-Dahlmann B, Hilbert A, Tuschen-Caffier B, Vocks S, Zeeck A, editors. S3-Leitlinie diagnostik und behandlung der essstörungen. Berlin, Heidelberg: Springer; 2019. p. 331–5.CrossRef Cuntz U, Walter C, Zipfel S. Körperliche folgeerkrankungen von essstörungen. In: Herpertz S, Fichter M, Herpetz-Dahlmann B, Hilbert A, Tuschen-Caffier B, Vocks S, Zeeck A, editors. S3-Leitlinie diagnostik und behandlung der essstörungen. Berlin, Heidelberg: Springer; 2019. p. 331–5.CrossRef
6.
Zurück zum Zitat Abe Y, Kondo M, Matsuoka R, Araki M, Dohyama K, Tanio H. Assessment of clinical features in transient left ventricular apical ballooning. J Am Coll Cardiol. 2003;41:737–42.CrossRef Abe Y, Kondo M, Matsuoka R, Araki M, Dohyama K, Tanio H. Assessment of clinical features in transient left ventricular apical ballooning. J Am Coll Cardiol. 2003;41:737–42.CrossRef
7.
Zurück zum Zitat Nef HM, Möllmann H, Hilpert P, Hamm C, Elsässer A. Tako-Tsubo-Kardiomyopathie. Dtsch Med Wochenschr. 2008;133:1629–36.CrossRef Nef HM, Möllmann H, Hilpert P, Hamm C, Elsässer A. Tako-Tsubo-Kardiomyopathie. Dtsch Med Wochenschr. 2008;133:1629–36.CrossRef
8.
Zurück zum Zitat Templin C, Ghadri JR, Diekmann J, Napp C, Bataiosu DR, Jaguszewski M, et al. Clinical features and outcomes of takotsubo (stress) cardiomyopathy. N Engl J Med. 2015;373:929–38.CrossRef Templin C, Ghadri JR, Diekmann J, Napp C, Bataiosu DR, Jaguszewski M, et al. Clinical features and outcomes of takotsubo (stress) cardiomyopathy. N Engl J Med. 2015;373:929–38.CrossRef
9.
Zurück zum Zitat Tsuchihashi K, Ueshima K, Uchida T, Oh-mura N, Kimura K, Owa M, et al. Transient left ventricular apical ballooning without coronary artery stenosis: A novel heart syndrome mimicking acute myocardial infarction. J Am Coll Cardiol. 2001;38:11–8.CrossRef Tsuchihashi K, Ueshima K, Uchida T, Oh-mura N, Kimura K, Owa M, et al. Transient left ventricular apical ballooning without coronary artery stenosis: A novel heart syndrome mimicking acute myocardial infarction. J Am Coll Cardiol. 2001;38:11–8.CrossRef
10.
Zurück zum Zitat Dote K, Sato H, Tateishi H, Uchida T, Ishihara M. Myocardial stunning due to simultaneous multivessel coronary spasms: a review of 5 cases. J Cardiol. 1991;21:203–14.PubMed Dote K, Sato H, Tateishi H, Uchida T, Ishihara M. Myocardial stunning due to simultaneous multivessel coronary spasms: a review of 5 cases. J Cardiol. 1991;21:203–14.PubMed
11.
Zurück zum Zitat Medeiros K, O’Connor MJ, Baicu CF, Fitzgibbons TP, Shaw P, Tighe DA, et al. Systolic and diastolic mechanics in stress cardiomyopathy. Circulation. 2014;129:1659–67.CrossRef Medeiros K, O’Connor MJ, Baicu CF, Fitzgibbons TP, Shaw P, Tighe DA, et al. Systolic and diastolic mechanics in stress cardiomyopathy. Circulation. 2014;129:1659–67.CrossRef
12.
Zurück zum Zitat Fineschi V, Michalodimitrakis M, D’Errico S, Neri M, Pomara C, Riezzo I, et al. Insight into stress-induced cardiomyopathy and sudden cardiac death due to stress. A forensic cardio-pathologist point of view. Forensic Sci Int. 2010;194:1–8.CrossRef Fineschi V, Michalodimitrakis M, D’Errico S, Neri M, Pomara C, Riezzo I, et al. Insight into stress-induced cardiomyopathy and sudden cardiac death due to stress. A forensic cardio-pathologist point of view. Forensic Sci Int. 2010;194:1–8.CrossRef
13.
Zurück zum Zitat Kammal A, Püschel K, Tsokos M. Tako-Tsubo-Kardiomyopathie Rechtsmed. 2015;25:474–80.CrossRef Kammal A, Püschel K, Tsokos M. Tako-Tsubo-Kardiomyopathie Rechtsmed. 2015;25:474–80.CrossRef
14.
Zurück zum Zitat Saito Y. Hypoglycemic attack: A rare triggering factor for takotsubo cardiomyopathy. Intern Med. 2005;44:171–2.CrossRef Saito Y. Hypoglycemic attack: A rare triggering factor for takotsubo cardiomyopathy. Intern Med. 2005;44:171–2.CrossRef
15.
Zurück zum Zitat Ansari M, Prasad A, Pellikka P, Klarich K. Takotsubo cardiomyopathy caused by hypoglycemia: a unique association with coronary arterial calcification. Int J Cardiol. 2011;147:e21–3.CrossRef Ansari M, Prasad A, Pellikka P, Klarich K. Takotsubo cardiomyopathy caused by hypoglycemia: a unique association with coronary arterial calcification. Int J Cardiol. 2011;147:e21–3.CrossRef
16.
Zurück zum Zitat Fedorowicz VJ, Falissard B, Foulon C, Dardennes R, Divac SM, Guelfi JD, et al. Factors associated with suicidal behaviors in a large French sample of inpatients with eating disorders. Int J Eat Disord. 2007;40:589–95.CrossRef Fedorowicz VJ, Falissard B, Foulon C, Dardennes R, Divac SM, Guelfi JD, et al. Factors associated with suicidal behaviors in a large French sample of inpatients with eating disorders. Int J Eat Disord. 2007;40:589–95.CrossRef
17.
Zurück zum Zitat Hoek HW. Incidence, prevalence and mortality of anorexia nervosa and other eating disorders. Curr Opin Psychiatry. 2006;19:389–94.CrossRef Hoek HW. Incidence, prevalence and mortality of anorexia nervosa and other eating disorders. Curr Opin Psychiatry. 2006;19:389–94.CrossRef
18.
Zurück zum Zitat Kaplan M, McFarland B, Huguet N. The relationship of body weight to suicide risk among men and women. J Nerv Ment Dis. 2007;195:948–51.CrossRef Kaplan M, McFarland B, Huguet N. The relationship of body weight to suicide risk among men and women. J Nerv Ment Dis. 2007;195:948–51.CrossRef
19.
Zurück zum Zitat Landi K. A review of anorexia and bulimia nervosa for the forensic pathologist. Acad Forensic Pathol. 2013;3:54–61.CrossRef Landi K. A review of anorexia and bulimia nervosa for the forensic pathologist. Acad Forensic Pathol. 2013;3:54–61.CrossRef
20.
Zurück zum Zitat Zipfel S, Löwe B, Reas DL, Deter H, Herzog W. Long-term prognosis in anorexia nervosa: lessons from a 21-year follow-up study. Lancet. 2000;355:721–2.CrossRef Zipfel S, Löwe B, Reas DL, Deter H, Herzog W. Long-term prognosis in anorexia nervosa: lessons from a 21-year follow-up study. Lancet. 2000;355:721–2.CrossRef
21.
Zurück zum Zitat Mehler P, Brown C. Anorexia nervosa-medical complications. J. Eat Disord. 2015;3:11.CrossRef Mehler P, Brown C. Anorexia nervosa-medical complications. J. Eat Disord. 2015;3:11.CrossRef
Metadaten
Titel
Fatal bleeding after transfemoral coronary angiography in anorexia nervosa
verfasst von
Inga Duval
Elke Doberentz
Burkhard Madea
Publikationsdatum
04.02.2021
Verlag
Springer US
Erschienen in
Forensic Science, Medicine and Pathology / Ausgabe 3/2021
Print ISSN: 1547-769X
Elektronische ISSN: 1556-2891
DOI
https://doi.org/10.1007/s12024-021-00354-4

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