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05.03.2020 | Original Article

Fatigue and contributing factors in Chinese patients with ankylosing spondylitis

verfasst von: Wei Zhou, Jiaxin Guo, Mei He, Jing Li, Yuanyuan Chen, Jiefu Liu, Rui Zhao, Yilin Wang, Xingyu Ge, Junling Yang, Zhifeng Gu, Chen Dong

Erschienen in: Clinical Rheumatology | Ausgabe 8/2020

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Abstract

Objectives

Fatigue is a common symptom in patients with ankylosing spondylitis (AS). However, fatigue of AS patients has not been well elucidated in China. This study aimed to evaluate the predictors of fatigue and the effects of fatigue on health-related quality of life among patients with AS.

Method

A total of 150 AS patients were involved in the study. A series of questionnaires included the following: Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Bath Ankylosing Spondylitis Metrology Index (BASMI), Bath Ankylosing Spondylitis Functional Index (BASFI), the 10-cm Visual Analog Scale (VAS), the Self-Rating Anxiety Scale (SAS), the Self-Rating Depression Scale (SDS), the Pittsburgh Sleep Quality Index (PSQI), the Health Assessment Questionnaire-Disability Index (HAQ-DI), the Short Form 36 Health Survey (SF-36), and the Fatigue Severity Scale (FSS). Independent samples t test, Mann-Whitney U test, chi-square analysis, Pearson/Spearman correlation, and binary logistic regression were used to analyze the data.

Results

The results demonstrated that 48.7% individuals with AS suffered from fatigue. Binary logistic regression indicated that waist-to-hip ratio, BASDAI, and sleep disturbance were independent predictors of fatigue in AS patients. Meanwhile, severe fatigue led to lower quality of life.

Conclusion

These findings suggested that medical personnel should pay more attention to AS patients with fatigue and take effective measures to relieve fatigue.

Key Points

• Incidence of fatigue in AS patients is 48.7% according to this cross-sectional study.

• The occurrence of fatigue was associated with higher WHR, higher BASDAI, and sleep disturbance.

• We also found that the occurrence of fatigue significantly reduced the quality of life in AS patients both physically and psychologically.

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Titel: Fatigue and contributing factors in Chinese patients with ankylosing spondylitis
verfasst von: Wei Zhou
Jiaxin Guo
Mei He
Jing Li
Yuanyuan Chen
Jiefu Liu
Rui Zhao
Yilin Wang
Xingyu Ge
Junling Yang
Zhifeng Gu
Chen Dong
Publikationsdatum: 05.03.2020
Verlag: Springer International Publishing
Erschienen in: Clinical Rheumatology / Ausgabe 8/2020
Print ISSN: 0770-3198
Elektronische ISSN: 1434-9949
DOI: https://doi.org/10.1007/s10067-020-04976-x

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Fatigue and contributing factors in Chinese patients with ankylosing spondylitis

Abstract

Objectives

Method

Results

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Conclusion

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