Skip to main content

15.11.2019 | Female Sexual Dysfunction and Disorders (T Lorenz & R Nappi, Section Editors) | Ausgabe 4/2019

Current Sexual Health Reports 4/2019

Female Sexual Dysfunction as a Warning Sign of Chronic Disease Development

Current Sexual Health Reports > Ausgabe 4/2019
Vincenza Di Stasi, Nunzia Verde, Elisa Maseroli, Irene Scavello, Sarah Cipriani, Tommaso Todisco, Mario Maggi, Linda Vignozzi
Wichtige Hinweise
Vincenza Di Stasi and Nunzia Verde contributed equally to this work.
This article is part of the Topical Collection on Female Sexual Dysfunction and Disorders

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.


Purpose of Review

Female sexual dysfunctions (FSD) in chronic diseases are often multi-factorial, integrating several bio-psychological and socio-environmental components. The aim of this review is to summarize existing evidence on the association between the most common chronic conditions and FSD and also to frame systematically experimental findings into a comprehensive overview on candidate mechanisms through which chronic diseases drive FSD pathogenesis.

Recent Findings

In men, it is now clear that several chronic diseases favour the development of sexual dysfunction (SD), especially erectile dysfunction (ED), by an integration of multiple pathogenic factors. More importantly, in men, ED has been recognized as a harbinger of several serious underlying medical conditions, including the cardiovascular ones. Conversely, the nature of the relationship between SD and chronic diseases in women remains controversial and, in contrast to the well-established associations with ED in men, FSD is not yet acknowledged as a warning sign of other systemic diseases. In this review of literature, we try to demonstrate that this is changing because there are some clinical and research evidences about the importance to recognize FSD in chronic disease. Specifically, we summarize the recent findings about the relation between cardio-metabolic, respiratory, renal, neurologic and rheumatic diseases and FSD.


Management of FSD is an important task to improve the overall quality of life of patients suffering from chronic, longstanding and often progressive diseases. It is also possible that sexual symptoms might be a warning sign for unrecognized conditions, although this is far to be completely understood. Further studies are needed to fully understand and treat this emerging topic in specific clinical settings.

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

e.Med Interdisziplinär

Für Ihren Erfolg in Klinik und Praxis - Die beste Hilfe in Ihrem Arbeitsalltag als Mediziner

Mit e.Med Interdisziplinär erhalten Sie Zugang zu allen CME-Fortbildungen und Fachzeitschriften auf

Über diesen Artikel

Weitere Artikel der Ausgabe 4/2019

Current Sexual Health Reports 4/2019 Zur Ausgabe

Female Sexual Dysfunction and Disorders (A Pastuszak and N Thirumavalavan, Section Editors)

A Review of Genome Wide Association Studies for Erectile Dysfunction

Female Sexual Dysfunction and Disorders (A Pastuszak and N Thirumavalavan, Section Editors)

The Complex Relationship Between Erectile Dysfunction and Hypogonadism in Diabetes Mellitus

Female Sexual Dysfunction and Disorders (T Lorenz and R Nappi, Section Editors)

Evolutionary Perspectives on Hypoactive Sexual Desire Disorder in Women

Female Sexual Dysfunction and Disorders (T Lorenz amd R Nappi, Section Editors)

Interactions Between Inflammation and Female Sexual Desire and Arousal Function

Male and Female Surgical Interventions (C Carson and M Khera, Section Editors)

Surgical Techniques and Pitfalls for Excision and Grafting

Neu im Fachgebiet Urologie

Mail Icon II Newsletter

Bestellen Sie unseren kostenlosen Newsletter Update Urologie und bleiben Sie gut informiert – ganz bequem per eMail.