Background
Methods
Study population
CMR protocol
CMR data analysis
Echocardiography
Clinical outcome
Statistical analysis
Results
Diagnosis | Surgery | BW | GACMR | GAbirth | ICU | Outcome |
---|---|---|---|---|---|---|
(kg) | (weeks) | (weeks) | (days) | |||
Group 1 Normal (n = 12)
| ||||||
Normal | No surgery | [2.0,4.0] | [30,39] | [37,41] | 0 | survived |
Group 2 AS/CoA (n = 7)
| ||||||
THAA | Hybrid, biventricular repair | 2.9 | 37 | 37 | 68 | survived |
MS, AS | Ross and MV replacement | 3.1 | 34 | 37 | 20 | survived |
CoA | Coarctation repair | 3.2 | 34 | 38 | 2 | survived |
CoA | Coarctation repair | 3.2 | 35 | 38 | 8 | survived |
MS, AS | Hybrid | 3.6 | 38 | 38 | 6 | survived |
MS, THAA, VSD | Coarctation/VSD repair, resection supramitral ring | 3.1 | 36 | 40 | 14 | survived |
CoA, Arnold-Chiari malformation | Coarctation repair | 3.4 | 35 | 40 | 17 | survived |
Group 3 HLHS UAS (n = 12)
| ||||||
HLHS UAS, MS, AA | Norwood | 3.2 | 33 | 39 | 29 | survived |
HLHS UAS, MS, AA | no surgery | NA | 34 | NA | NA | termination of pregnancy (35 weeks GA) |
HLHS UAS, MS, AA | Hybrid | 3.6 | 34 | 40 | 18 | survived |
HLHS UAS, MA, AA | Norwood | 3.1 | 35 | 39 | 17 | survived |
HLHS UAS, MA, AA | Hybrid | 3.9 | 38 | 40 | 13 | survived |
HLHS UAS, MA, AA | Norwood | 3.7 | 35 | 40 | 16 | survived |
HLHS UAS, MS, AA | Norwood | 3.2 | 32 | 36 | 25 | survived |
HLHS UAS, MA, AA, LAI | Norwood | 3.6 | 35 | 41 | 6 | survived |
HLHS UAS, MA, AA | Norwood | 3.1 | 37 | 38 | 17 | survived |
HLHS UAS, MA, AA | Norwood | 3.0 | 37 | 38 | 4 | survived |
HLHS UAS, MA, AA | Hybrid, Norwood | 2.8 | 35 | 37 | 119 | survived |
HLHS UAS, MA, AA | Norwood | 3.6 | 35 | 39 | 14 | survived |
Group 4 HLHS I/HRAS (n = 3)
| ||||||
HLHS, MS, AA, TAPVC | Fetal stent, Norwood | 3.1 | 32 | 38 | 99 | survived |
HLHS I/HRAS, MS, AA | Fetal stent, Hybrid | 3.0 | 35 | 40 | 46 | deceased (2 weeks) |
HLHS I/HRAS, MA, AA | Fetal stent | NA | 36 | NA | NA | deceased (36 weeks GA) |
CVO | MPA | AAo | SVC | PBF | FO | DA | DAo | UV |
---|---|---|---|---|---|---|---|---|
Group 1 Normal (n = 12)
| ||||||||
540 | 327 | 198 | 147 | 106 | 107 | 220 | 273 | 160 |
[419,734] | [229,440] | [145,272] | [107,279] | [6,178] | [5,204] | [173,287] | [163,418] | [101,311] |
Group 2 AS/CoA (n = 7)
| ||||||||
454 | 351 | 89 | 134 | 78 | 25 | 266 | 253 | 153 |
[392,569] | [321,400] | [51,152] | [107,152] | [40,152] | [−49,69] | [238,318] | [199,324] | [108,198] |
Group 3 HLHS UAS (n = 13)
| ||||||||
456 | 456 | 0 | 132 | 81 | −81 | 358 | 246 | 133 |
[350,596] | [350,596] | [0,0] | [70,231] | [30,140] | [−140,-30] | [300,456] | [165,337] | [101,165] |
Group 4 HLHS I/HRAS (n = 3)
| ||||||||
331 | 331 | 0 | 112 | 21 | −21 | 300 | 227 | 135 |
[114,479] | [114,479] | [0,0] | [21,195] | [10,38] | [−38,-10] | [89,427] | [75,307] | [57,251] |