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Erschienen in: Child's Nervous System 7/2017

16.05.2017 | Focus Session

Fetal ventriculomegaly: Diagnosis, treatment, and future directions

verfasst von: Jared M. Pisapia, Saurabh Sinha, Deborah M. Zarnow, Mark P. Johnson, Gregory G. Heuer

Erschienen in: Child's Nervous System | Ausgabe 7/2017

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Abstract

Fetal ventriculomegaly (VM) refers to the enlargement of the cerebral ventricles in utero. It is associated with the postnatal diagnosis of hydrocephalus. VM is clinically diagnosed on ultrasound and is defined as an atrial diameter greater than 10 mm. Because of the anatomic detailed seen with advanced imaging, VM is often further characterized by fetal magnetic resonance imaging (MRI). Fetal VM is a heterogeneous condition with various etiologies and a wide range of neurodevelopmental outcomes. These outcomes are heavily dependent on the presence or absence of associated anomalies and the direct cause of the ventriculomegaly rather than on the absolute degree of VM. In this review article, we discuss diagnosis, work-up, counseling, and management strategies as they relate to fetal VM. We then describe imaging-based research efforts aimed at using prenatal data to predict postnatal outcome. Finally, we review the early experience with fetal therapy such as in utero shunting, as well as the advances in prenatal diagnosis and fetal surgery that may begin to address the limitations of previous therapeutic efforts.
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Metadaten
Titel
Fetal ventriculomegaly: Diagnosis, treatment, and future directions
verfasst von
Jared M. Pisapia
Saurabh Sinha
Deborah M. Zarnow
Mark P. Johnson
Gregory G. Heuer
Publikationsdatum
16.05.2017
Verlag
Springer Berlin Heidelberg
Erschienen in
Child's Nervous System / Ausgabe 7/2017
Print ISSN: 0256-7040
Elektronische ISSN: 1433-0350
DOI
https://doi.org/10.1007/s00381-017-3441-y

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