Clavicle fractures are one of the most common around the shoulder girdle, accounting for 2.6% of all fractures and 44% of shoulder girdle fractures. Notably, the majority of clavicle fractures occur at the midshaft of the clavicle (81%), which associates with displacement in 48% of cases and with comminuted patterns in 19% [
1]. These fractures are generally treated conservatively [
2], but those with severely displaced or comminuted patterns have high risk for delayed union or nonunion and are indicated for surgical treatment [
3‐
5]. Among the surgical options for treating midshaft clavicular fractures, plate fixation—either superior or anteroinferior placement—continues to be the most popular surgery due to the plate’s excellent biomechanical strength [
6] and reliable clinical outcomes [
5]. However, postoperative complications with implant failures, caused by plate deformation or breakage, have still required revision surgery in as many as 6.9–16.7% of plate fixations [
7‐
10], especially when wedge or comminuted fractures have been present due to the direct negative impact on the fixation stability [
11]. A previous study identified two risk factors for plate breakage: the use of a reconstruction plate and the bridging plate technique [
7]. Moreover, a recent finite element analysis study on clavicle fracture fixation showed that the maximum stress in the precontoured superior reconstruction plate fixation without lag screws occurred at the edge of screw holes above fracture zone (SHFZ) [
12]. To the best of our knowledge, no previous study has evaluated the biomechanical response of the superior clavicle locking plate (SCLP) without SHFZ. We hypothesized that a new SCLP design without SHFZ would have better biomechanical behaviors for comminuted midshaft clavicular fracture fixation than the standard SCLP (with SHFZ) in terms of the stress distribution under mechanical load. Therefore, the aim of this study was to perform a comparative stress analysis between the SCLP with and without SHFZ in comminuted midshaft clavicular fracture fixation.