Ausgabe 1/2020
Inhalt (72 Artikel)
Extracranial versus intracranial hydro-hemodynamics during aging: a PC-MRI pilot cross-sectional study
Armelle Lokossou, Serge Metanbou, Catherine Gondry-Jouet, Olivier Balédent
Genetic disruption of slc4a10 alters the capacity for cellular metabolism and vectorial ion transport in the choroid plexus epithelium
Inga Baasch Christensen, Qi Wu, Anders Solitander Bohlbro, Marianne Gerberg Skals, Helle Hasager Damkier, Christian Andreas Hübner, Robert Andrew Fenton, Jeppe Praetorius
Human CD4+ T cell subsets differ in their abilities to cross endothelial and epithelial brain barriers in vitro
Hideaki Nishihara, Sasha Soldati, Adrien Mossu, Maria Rosito, Henriette Rudolph, William A. Muller, Daniela Latorre, Federica Sallusto, Mireia Sospedra, Roland Martin, Hiroshi Ishikawa, Tobias Tenenbaum, Horst Schroten, Fabien Gosselet, Britta Engelhardt
Non-invasive MRI quantification of cerebrospinal fluid dynamics in amyotrophic lateral sclerosis patients
Lucas R. Sass, Mohammadreza Khani, Jacob Romm, Marianne Schmid Daners, Kyle McCain, Tavara Freeman, Gregory T. Carter, Douglas L. Weeks, Brian Petersen, Jason Aldred, Dena Wingett, Bryn A. Martin
Simvastatin, edaravone and dexamethasone protect against kainate-induced brain endothelial cell damage
Lilla Barna, Fruzsina R. Walter, András Harazin, Alexandra Bocsik, András Kincses, Vilmos Tubak, Katalin Jósvay, Ágnes Zvara, Patricia Campos-Bedolla, Mária A. Deli
Corticospinal excitability in idiopathic normal pressure hydrocephalus: a transcranial magnetic stimulation study
Jani Sirkka, Laura Säisänen, Petro Julkunen, Mervi Könönen, Elisa Kallioniemi, Ville Leinonen, Nils Danner
Chemokine CXCL13 in serum, CSF and blood–CSF barrier function: evidence of compartment restriction
Georg Pilz, Irma Sakic, Peter Wipfler, Jörg Kraus, Elisabeth Haschke-Becher, Wolfgang Hitzl, Eugen Trinka, Andrea Harrer
Effects of aging on hydrocephalus after intraventricular hemorrhage
Yingfeng Wan, Feng Gao, Fenghui Ye, Weiming Yang, Ya Hua, Richard F. Keep, Guohua Xi
Longitudinal analysis of cerebral aqueduct flow measures: multiple sclerosis flow changes driven by brain atrophy
Dejan Jakimovski, Robert Zivadinov, Bianca Weinstock-Guttman, Niels Bergsland, Michael G. Dwyer, Marcella Maria Lagana
Cerebrospinal fluid dynamics modulation by diet and cytokines in rats
Zerin Alimajstorovic, Ester Pascual-Baixauli, Cheryl A. Hawkes, Basil Sharrack, A. Jane Loughlin, Ignacio A. Romero, Jane E. Preston
Abnormalities in spinal cord ultrastructure in a rat model of post-traumatic syringomyelia
Joel Berliner, Sarah Hemley, Elmira Najafi, Lynne Bilston, Marcus Stoodley, Magdalena Lam
CNS fluid and solute movement: physiology, modelling and imaging
Hazel C. Jones, Richard F. Keep, Lester R. Drewes
Hypercholesterolemia negatively influences morphology and molecular markers of epithelial cells within the choroid plexus in rabbits
Fumiko Obata, Keishi Narita
Increased age and male sex are independently associated with higher frequency of blood–cerebrospinal fluid barrier dysfunction using the albumin quotient
Massimiliano Castellazzi, Andrea Morotti, Carmine Tamborino, Francesca Alessi, Silvy Pilotto, Eleonora Baldi, Luisa M. Caniatti, Alessandro Trentini, Ilaria Casetta, Enrico Granieri, Maura Pugliatti, Enrico Fainardi, Tiziana Bellini
Aquaporin 1 and the Na+/K+/2Cl− cotransporter 1 are present in the leptomeningeal vasculature of the adult rodent central nervous system
Qianliang Li, Nadia N. Aalling, Benjamin Förstera, Ali Ertürk, Maiken Nedergaard, Kjeld Møllgård, Anna L. R. Xavier
Quantitatively relating brain endothelial cell–cell junction phenotype to global and local barrier properties under varied culture conditions via the Junction Analyzer Program
Kelsey M. Gray, Jae W. Jung, Collin T. Inglut, Huang-Chiao Huang, Kimberly M. Stroka
Choroid plexus LAT2 and SNAT3 as partners in CSF amino acid homeostasis maintenance
Elena Dolgodilina, Simone M. Camargo, Eva Roth, Brigitte Herzog, Virginia Nunes, Manuel Palacín, Francois Verrey
Secondary deterioration in patients with normal pressure hydrocephalus after ventriculoperitoneal shunt placement: a proposed algorithm of treatment
Pawel Gutowski, Sergej Rot, Michael Fritsch, Ullrich Meier, Leonie Gölz, Johannes Lemcke
The pivotal role of micro-environmental cells in a human blood–brain barrier in vitro model of cerebral ischemia: functional and transcriptomic analysis
Anna Gerhartl, Nadja Pracser, Alexandra Vladetic, Sabrina Hendrikx, Heinz-Peter Friedl, Winfried Neuhaus
This was the year that was: brain barriers and brain fluid research in 2019
Richard F. Keep, Hazel C. Jones, Lester R. Drewes
Autophagy-mediated occludin degradation contributes to blood–brain barrier disruption during ischemia in bEnd.3 brain endothelial cells and rat ischemic stroke models
Kyeong-A Kim, Donghyun Kim, Jeong-Hyeon Kim, Young-Jun Shin, Eun-Sun Kim, Muhammad Akram, Eun-Hye Kim, Arshad Majid, Seung-Hoon Baek, Ok-Nam Bae
In vitro modeling of the neurovascular unit: advances in the field
Aditya Bhalerao, Farzane Sivandzade, Sabrina Rahman Archie, Ekram Ahmed Chowdhury, Behnam Noorani, Luca Cucullo
In vitro and numerical simulation of blood removal from cerebrospinal fluid: comparison of lumbar drain to Neurapheresis therapy
Mohammadreza Khani, Lucas R. Sass, M. Keith Sharp, Aaron R. McCabe, Laura M. Zitella Verbick, Shivanand P. Lad, Bryn A. Martin
Cerebrospinal fluid dynamics in non-acute post-traumatic ventriculomegaly
Afroditi D. Lalou, Virginia Levrini, Marek Czosnyka, Laurent Gergelé, Matthew Garnett, Angelos Kolias, Peter J. Hutchinson, Zofia Czosnyka
Laminin 221 fragment is suitable for the differentiation of human induced pluripotent stem cells into brain microvascular endothelial-like cells with robust barrier integrity
Hiromasa Aoki, Misaki Yamashita, Tadahiro Hashita, Takahiro Iwao, Tamihide Matsunaga
In vitro modeling of blood–brain barrier and interface functions in neuroimmune communication
Michelle A. Erickson, Miranda L. Wilson, William A. Banks
Angiomodulin (IGFBP7) is a cerebral specific angiocrine factor, but is probably not a blood–brain barrier inducer
Ofri Bar, Sivan Gelb, Kian Atamny, Shira Anzi, Ayal Ben-Zvi
Evidence for communication of peripheral iron status to cerebrospinal fluid: clinical implications for therapeutic strategy
James R. Connor, Kari Duck, Stephanie Patton, Ian A. Simpson, Lynn Marie Trotti, Richard Allen, Christopher J. Earley, David Rye
Intracranial pressure elevation alters CSF clearance pathways
Vegard Vinje, Anders Eklund, Kent-Andre Mardal, Marie E. Rognes, Karen-Helene Støverud
Recent advances in human iPSC-derived models of the blood–brain barrier
Michael J. Workman, Clive N. Svendsen
Serum-derived factors of breast cancer patients with brain metastases alter permeability of a human blood–brain barrier model
Carolin J. Curtaz, Constanze Schmitt, Saskia-Laureen Herbert, Jonas Feldheim, Nicolas Schlegel, Fabien Gosselet, Carsten Hagemann, Norbert Roewer, Patrick Meybohm, Achim Wöckel, Malgorzata Burek
Culture-induced changes in mRNA expression levels of efflux and SLC-transporters in brain endothelial cells
C. Goldeman, B. Ozgür, B. Brodin
The incidence of significant venous sinus stenosis and cerebral hyperemia in childhood hydrocephalus: prognostic value with regards to differentiating active from compensated disease
Grant Alexander Bateman, Swee Leong Yap, Gopinath Musuwadi Subramanian, Alexander Robert Bateman
Measuring intracranial pressure by invasive, less invasive or non-invasive means: limitations and avenues for improvement
Karen Brastad Evensen, Per Kristian Eide
Choroid plexus and the blood–cerebrospinal fluid barrier in disease
Peter Solár, Alemeh Zamani, Lucie Kubíčková, Petr Dubový, Marek Joukal
Inhibition of transforming growth factor beta signaling pathway promotes differentiation of human induced pluripotent stem cell-derived brain microvascular endothelial-like cells
Misaki Yamashita, Hiromasa Aoki, Tadahiro Hashita, Takahiro Iwao, Tamihide Matsunaga
Development of a human in vitro blood–brain tumor barrier model of diffuse intrinsic pontine glioma to better understand the chemoresistance
Clémence Deligne, Johan Hachani, Sophie Duban-Deweer, Samuel Meignan, Pierre Leblond, Angel M. Carcaboso, Yasuteru Sano, Fumitaka Shimizu, Takashi Kanda, Fabien Gosselet, Marie-Pierre Dehouck, Caroline Mysiorek
Advances in blood–brain barrier modeling in microphysiological systems highlight critical differences in opioid transport due to cortisol exposure
Jacquelyn A. Brown, Shannon L. Faley, Yajuan Shi, Kathleen M. Hillgren, Geri A. Sawada, Thomas K. Baker, John P. Wikswo, Ethan S. Lippmann
Long-term monitoring of intracranial pressure in freely-moving rats; impact of different physiological states
Sajedeh Eftekhari, Connar Stanley James Westgate, Katrine Printz Johansen, Signe Rath Bruun, Rigmor H. Jensen
Review: pathophysiology of intracranial hypertension and noninvasive intracranial pressure monitoring
Nicolas Canac, Kian Jalaleddini, Samuel G. Thorpe, Corey M. Thibeault, Robert B. Hamilton
Altered brain fluid management in a rat model of arterial hypertension
Daphne M. P. Naessens, Bram F. Coolen, Judith de Vos, Ed VanBavel, Gustav J. Strijkers, Erik N. T. P. Bakker
Potential pharmacological approaches for the treatment of HIV-1 associated neurocognitive disorders
Amila Omeragic, Olanre Kayode, Md Tozammel Hoque, Reina Bendayan
Compressed-sensing accelerated 4D flow MRI of cerebrospinal fluid dynamics
Elena Jaeger, Kristina Sonnabend, Frank Schaarschmidt, David Maintz, Kilian Weiss, Alexander C. Bunck
Modeling blood–brain barrier pathology in cerebrovascular disease in vitro: current and future paradigms
Anuska V. Andjelkovic, Svetlana M. Stamatovic, Chelsea M. Phillips, Gabriela Martinez-Revollar, Richard F. Keep
Characterization of a multicenter pediatric-hydrocephalus shunt biobank
Jacob Gluski, Paul Zajciw, Prashant Hariharan, Amanda Morgan, Diego M. Morales, Andrew Jea, William Whitehead, Neena Marupudi, Steven Ham, Sandeep Sood, James P. McAllister II, David D. Limbrick Jr., Carolyn A. Harris
Preterm intraventricular hemorrhage in vitro: modeling the cytopathology of the ventricular zone
Leandro Castaneyra-Ruiz, James P. McAllister II., Diego M. Morales, Steven L. Brody, Albert M. Isaacs, David D. Limbrick Jr.
Differential expression of receptors mediating receptor-mediated transcytosis (RMT) in brain microvessels, brain parenchyma and peripheral tissues of the mouse and the human
Wandong Zhang, Qing Yan Liu, Arsalan S. Haqqani, Sonia Leclerc, Ziying Liu, François Fauteux, Ewa Baumann, Christie E. Delaney, Dao Ly, Alexandra T. Star, Eric Brunette, Caroline Sodja, Melissa Hewitt, Jagdeep K. Sandhu, Danica B. Stanimirovic
Contribution of brain pericytes in blood–brain barrier formation and maintenance: a transcriptomic study of cocultured human endothelial cells derived from hematopoietic stem cells
Marjolein Heymans, Ricardo Figueiredo, Lucie Dehouck, David Francisco, Yasuteru Sano, Fumitaka Shimizu, Takashi Kanda, Rémy Bruggmann, Britta Engelhardt, Peter Winter, Fabien Gosselet, Maxime Culot
Location matters: highly divergent protein levels in samples from different CNS compartments in a clinical trial of rituximab for progressive MS
Joakim Bergman, Anders Svenningsson, Per Liv, Tommy Bergenheim, Joachim Burman
Chronic extradural compression of spinal cord leads to syringomyelia in rat model
Longbing Ma, Qingyu Yao, Can Zhang, Mo Li, Lei Cheng, Fengzeng Jian
Advancing brain barriers RNA sequencing: guidelines from experimental design to publication
David M. F. Francisco, Luca Marchetti, Sabela Rodríguez-Lorenzo, Eduardo Frías-Anaya, Ricardo M. Figueiredo, Marjolein Heymanns, Maxime Culot, Ana Raquel Santa-Maria, Maria A. Deli, Raoul F. V. Germano, Benoit Vanhollebeke, Nikolaos Kakogiannos, Monica Giannotta, Elisabetta Dejana, Amaia Dominguez-Belloso, Stefan Liebner, Markus Schuster, Harm-Anton Klok, Marie Wiatr, Horst Schroten, Tobias Tenenbaum, Gijs Kooij, Peter Winter, Ignacio Andres Romero, Helga E. de Vries, Britta Engelhardt, Rémy Bruggmann
Functional hyperemia drives fluid exchange in the paravascular space
Ravi Teja Kedarasetti, Kevin L. Turner, Christina Echagarruga, Bruce J. Gluckman, Patrick J. Drew, Francesco Costanzo
A face-to-face comparison of claudin-5 transduced human brain endothelial (hCMEC/D3) cells with porcine brain endothelial cells as blood–brain barrier models for drug transport studies
Birthe Gericke, Kerstin Römermann, Andreas Noack, Sandra Noack, Jessica Kronenberg, Ingolf Ernst Blasig, Wolfgang Löscher
Chemically defined human vascular laminins for biologically relevant culture of hiPSC-derived brain microvascular endothelial cells
Pedram Motallebnejad, Samira M. Azarin
The potential role of microvascular pathology in the neurological manifestations of coronavirus infection
M. A. MacLean, L. Kamintsky, E. D. Leck, A. Friedman
David S. Miller: Scientist, Mentor, Friend—a tribute and thank you
Björn Bauer, J. Larry Renfro, Karl J. Karnaky Jr., Rosalinde Masereeuw, Gert Fricker, Ron E. Cannon, Anika M. S. Hartz
Diabetes is associated with familial idiopathic normal pressure hydrocephalus: a case–control comparison with family members
Joel Räsänen, Joel Huovinen, Ville E. Korhonen, Antti Junkkari, Sami Kastinen, Simo Komulainen, Minna Oinas, Cecilia Avellan, Janek Frantzen, Jaakko Rinne, Antti Ronkainen, Mikko Kauppinen, Kimmo Lönnrot, Markus Perola, Anne M. Koivisto, Anne M. Remes, Hilkka Soininen, Mikko Hiltunen, Seppo Helisalmi, Mitja I. Kurki, Juha E. Jääskeläinen, Ville Leinonen
Non-invasive measurement of choroid plexus apparent blood flow with arterial spin labeling
Li Zhao, Manuel Taso, Weiying Dai, Daniel Z. Press, David C. Alsop
The incidence of obesity, venous sinus stenosis and cerebral hyperaemia in children referred for MRI to rule out idiopathic intracranial hypertension at a tertiary referral hospital: a 10 year review
Grant Alexander Bateman, Gopinath Musuwadi Subramanian, Swee Leong Yap, Alexander Robert Bateman
The microvascular extracellular matrix in brains with Alzheimer’s disease neuropathologic change (ADNC) and cerebral amyloid angiopathy (CAA)
Mamatha Damodarasamy, Robert B. Vernon, Jasmine L. Pathan, C. Dirk Keene, Anthony J. Day, William A. Banks, May J. Reed
LC–MS/MS-based in vitro and in vivo investigation of blood–brain barrier integrity by simultaneous quantitation of mannitol and sucrose
Behnam Noorani, Ekram Ahmed Chowdhury, Faleh Alqahtani, Yeseul Ahn, Dhavalkumar Patel, Abraham Al-Ahmad, Reza Mehvar, Ulrich Bickel
Identification and in vivo characterization of a brain-penetrating nanobody
Y Wouters, T Jaspers, B De Strooper, M Dewilde
Comparative investigation of different telemetric methods for measuring intracranial pressure: a prospective pilot study
S. Rot, M. Dweek, P. Gutowski, L. Goelz, U. Meier, J. Lemcke
Commentary on human pluripotent stem cell-based blood–brain barrier models
Ethan S. Lippmann, Samira M. Azarin, Sean P. Palecek, Eric V. Shusta
Cerebrospinal fluid analysis in 108 patients with progressive multifocal leukoencephalopathy
Nora Möhn, Yi Luo, Thomas Skripuletz, Philipp Schwenkenbecher, Anne Ladwig, Clemens Warnke, Sven G. Meuth, Heinz Wiendl, Catharina C. Gross, Christoph Schröder, Aiden Haghikia, Martin Stangel
Permeability of the windows of the brain: feasibility of dynamic contrast-enhanced MRI of the circumventricular organs
Inge C. M. Verheggen, Joost J. A. de Jong, Martin P. J. van Boxtel, Alida A. Postma, Frans R. J. Verhey, Jacobus F. A. Jansen, Walter H. Backes
Sex difference in cerebrospinal fluid/blood albumin quotients in patients with schizophreniform and affective psychosis
Sophie Meixensberger, Karl Bechter, Rick Dersch, Bernd Feige, Simon Maier, Miriam A. Schiele, Kimon Runge, Dominik Denzel, Kathrin Nickel, Derek Spieler, Horst Urbach, Harald Prüss, Katharina Domschke, Ludger Tebartz van Elst, Dominique Endres
Ex-vivo quantification of ovine pia arachnoid complex biomechanical properties under uniaxial tension
Gabryel Conley Natividad, Sophia K. Theodossiou, Nathan R. Schiele, Gordon K. Murdoch, Alkiviadis Tsamis, Bertrand Tanner, Gabriel Potirniche, Martin Mortazavi, David A. Vorp, Bryn A. Martin
A blood–brain barrier overview on structure, function, impairment, and biomarkers of integrity
Hossam Kadry, Behnam Noorani, Luca Cucullo
Water treadmill training attenuates blood-spinal cord barrier disruption in rats by promoting angiogenesis and inhibiting matrix metalloproteinase-2/9 expression following spinal cord injury
Xinwang Ying, Qingfeng Xie, Shengcun Li, Xiaolan Yu, Kecheng Zhou, Jingjing Yue, Xiaolong Chen, Wenzhan Tu, Guanhu Yang, Songhe Jiang
Cerebrospinal fluid drainage kinetics across the cribriform plate are reduced with aging
Molly Brady, Akib Rahman, Abigail Combs, Chethana Venkatraman, R. Tristan Kasper, Conor McQuaid, Wing-Chi Edmund Kwok, Ronald W. Wood, Rashid Deane
In Xenopus ependymal cilia drive embryonic CSF circulation and brain development independently of cardiac pulsatile forces
A. H. Dur, T. Tang, S. Viviano, A. Sekuri, H. R. Willsey, H. D. Tagare, K. T. Kahle, E. Deniz