Ausgabe 2/2025
Inhalt (22 Artikel)
Urinary excretion profiles of the orexin receptor antagonist suvorexant and its metabolites
- Original Article
Misato Wada, Hiroe Kamata, Noriaki Shima, Atsushi Nitta, Hidenao Kakehashi, Shihoko Fujii, Shuntaro Matsuta, Tooru Kamata, Munehiro Katagi, Hiroshi Nishioka
Identification of a novel imidazole-derived GABA agonist isopropoxate: simultaneous detection and quantification of imidazole-derived analogs from human hairs in abused cases by LC–MS/MS
- Original Article
Xiaolong Zhang, Yuxuan Chen, Jinlei Liu, Mengchao Wang, Yinyin Dai, Kundi Zhao, Jie Gu, Huimin Zhang, Amin Wurita, Koutaro Hasegawa
Benzoylmesaconine alters the native structure and activity of hen egg white lysozyme: revealing possible mechanism of aconitum-induced toxicity
- Original Article
Manka Marycleopha, Jennifer Johnson, Abhishek Singh, Satish Kumar
Detection and quantification of drugs on banknotes by LC–MS/MS with a fast and non-destructive sample preparation: a comparison of three cities
- Open Access
- Original Article
Göksun Demirel, Yeter Erol Öztürk, Oya Yeter, Hızır Aslıyüksek
GC/MS-based quantitative analysis of sulfide ion in whole blood using ethenesulfonyl fluoride as a derivatization reagent
- Open Access
- Original Article
Ryosuke Shiraki, Shin Ogawa, Kengo Wakigawa, Hidehiko Okazaki, Akinaga Gohda, Takeshi Mori, Yoshiki Katayama
Eleven new metabolites of fluvoxamine detected in the solid tissues and body fluids obtained from a deceased overdosed with fluvoxamine in vivo, and the metabolites in the human liver microsomes in vitro using LC-HR–MS/MS
- Original Article
Kayoko Minakata, Hideki Nozawa, Itaru Yamagishi, Kenta Yuyama, Masako Suzuki, Takuya Kitamoto, Minako Kondo, Osamu Suzuki, Koutaro Hasegawa
Analysis of cyanide exposure status in fire-related deaths using a physiologically based pharmacokinetic model
- Open Access
- Original Article
Kazuo Harada, Yuri Tokugawa, Kazunari Henmi, Yohei Miyashita, Yuji Sakahashi, Taichi Nishihori, Yukari Sakamoto, Chihpin Yang, Yu Isobe, Kana Sugimoto, Kentaro Nakama, Ryuichi Katada, Hiroshi Matsumoto
Enzymatic hydrolysis of ∆8-THC-O, ∆9-THC-O, 11-α-HHC-O, and 11-β-HHC-O by pooled human liver microsomes to generate ∆8-THC, ∆9-THC, 11-α-HHC, and 11-β-HHC
- Original Article
Shuangli Zhao, Jorge Carlos Pineda García, Ren-shi Li, Ruri Kikura-Hanajiri, Yosuke Demizu, Yoshitaka Tanaka, Yuji Ishii
Acute and subacute cardiovascular effects of synthetic cannabinoid JWH-018 in rat
- Open Access
- Original Article
Onural Ozhan, Necip Ermis, Osman Celbis, Emine Samdanci, Semih Petekkaya, Mucahit Oruc, Ozcan Soylu, Pelin Koparir, Ahmet Acet, Hakan Parlakpinar
Evaluation of dried blood spot sampling for verification of exposure to chemical threat agents
- Open Access
- Original Article
Katie A. Walker, Trinity K. Rudd, Justin N. Vignola, Thomas M. McClymont, Noah D. Roberts, Kevin Laitipaya, Robert C. diTargiani
Preparation of highly concentrated extracts from large volume of urine as the first step in detecting trace amounts of hypnotics in urine collected in drug-facilitated crime cases
- Original Article
Kenji Kuwayama, Hajime Miyaguchi, Tatsuyuki Kanamori, Kenji Tsujikawa, Tadashi Yamamuro, Hiroki Segawa, Yuki Okada, Yuko T. Iwata
Electromembrane extraction (EME)–LC–MS/MS of khat: improving separation and determination of bioactive ingredients in traditional plant and vitreous humor
- Original Article
Aijia Zhang, Shuang Ye, Zilong Liu, Lingzhi Tan, Man Liang
Development of a novel Δ9-THC-specific color test reagent
- Original Article
Kenji Tsujikawa, Yuki Okada, Hiroki Segawa, Tadashi Yamamuro, Kenji Kuwayama, Tatsuyuki Kanamori, Yuko. T. Iwata
Evaluating the value of entomotoxicology in forensic toxicology casework using the first minipig model
- Open Access
- Original Article
Olwen C. Groth, Anaëlle Pi, Andres E. Jensen, Frank Reckel, Jiri Hodecek, Abderrahmane Kori Yahia, Susan Rahaus, Martin H. Villet, Matthias Graw
Beware of misattributing ‘modafinil’ in diphenhydramine-positive cases
- Short Communication
Karolina Nowak, Marcin Zawadzki, Paweł Szpot
Investigation of commercially available recombinant and conventional β-glucuronidases to evaluate the hydrolysis efficiencies against O-glucuronides and N-glucuronides in urinary drug screening
- Open Access
- Short Communication
Akira Namera, Takeshi Saito, Masataka Nagao
Cross-reactivity of the epimers of 11-nor-9-carboxy-hexahydrocannabinol, metabolites of hexahydrocannabinol, with panel tests for urinary Δ9-tetrahydrocannabinol metabolites
- Short Communication
Kenji Tsujikawa, Yuki Okada, Hiroki Segawa, Tadashi Yamamuro, Kenji Kuwayama, Tatsuyuki Kanamori, Yuko. T. Iwata
Identification of two lysergic acid diethylamide analogs, 1-(3-(trimethylsilyl) propionyl) lysergic acid diethylamide (1S-LSD) and 1-(2-thienoyl)-6-allyl-nor-d-lysergic acid diethylamide (1T-AL-LAD), in paper sheet products distributed on the internet
- Short Communication
Rie Tanaka, Maiko Kawamura, Michiho Ito, Ruri Kikura-Hanajiri
Quantitative analysis of stimulants in whole blood using an evaporation free precipitation salt assisted liquid–liquid extraction (SALLE) sample preparation approach
- Short Communication
Jon Stephenson, Joseph Austin, Bailey Carney, Melanie Flater, Skye Mullarkey, Michael Morrison
Method for determination of cytisine in post-mortem biological matrices and its application to two forensic cases
- Case Report
Karolina Nowak, Paweł Szpot, Marcin Zawadzki, Agnieszka Chłopaś-Konowałek
Non-consensual administration of mifepristone for hidden abortion: a rare case of drug-facilitated crime
- Case Report
Laurie Gheddar, Audrey Farrugia, Jean-Sébastien Raul, Pascal Kintz
A simple method for the determination of stimulant substances in postmortem blood: development, validation, and application in nearly 1000 forensic cases
- Case Report
Letícia Birk, Bruno Pereira dos Santos, Daniela Souza Ossanes, Patrícia de Souza Schwarz, Mariana Lopes Mesquita, Sarah Eller, Tiago Franco de Oliveira