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Erschienen in: Rechtsmedizin 2/2019

21.03.2019 | CME

Aktuelles zur forensisch-toxikologischen Haaranalytik

verfasst von: Prof. Dr. F. Musshoff

Erschienen in: Rechtsmedizin | Ausgabe 2/2019

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Zusammenfassung

Aufgrund von Innovationen in den Analysetechniken hat sich auch die forensisch-toxikologische Haaranalytik stetig weiterentwickelt. Doch neben der reinen Analytik gilt es, erhaltene Befunde mit einer großen sachverständigen Erfahrung zu interpretieren. Aktuelle Möglichkeiten und Grenzen der Haaranalytik werden aufgezeigt.
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Literatur
1.
Zurück zum Zitat Madea B, Musshoff F (2004) Haaranalytik, Technik und Interpretation in Medizin und Recht. Deutscher Ärzte-Verlag, Köln Madea B, Musshoff F (2004) Haaranalytik, Technik und Interpretation in Medizin und Recht. Deutscher Ärzte-Verlag, Köln
2.
Zurück zum Zitat Musshoff F, Madea B (2007) New trends in hair analysis and scientific demands on validation and technical notes. Forensic Sci Int 165(2–3):204–215CrossRef Musshoff F, Madea B (2007) New trends in hair analysis and scientific demands on validation and technical notes. Forensic Sci Int 165(2–3):204–215CrossRef
3.
Zurück zum Zitat Musshoff F, Madea B (2007) Analytical pitfalls in hair testing. Anal Bioanal Chem 388(7):1475–1479CrossRef Musshoff F, Madea B (2007) Analytical pitfalls in hair testing. Anal Bioanal Chem 388(7):1475–1479CrossRef
4.
Zurück zum Zitat Pragst F (2004) Oral presentation at the Joint GTFCh/TIAFT Symposium “Analytical pitfalls and trends in clinical and forensic toxicology” during the Analytica Conference, May 12th, 2004 in Munich, Germany. Toxichem Krimtech 71:69–83 Pragst F (2004) Oral presentation at the Joint GTFCh/TIAFT Symposium “Analytical pitfalls and trends in clinical and forensic toxicology” during the Analytica Conference, May 12th, 2004 in Munich, Germany. Toxichem Krimtech 71:69–83
5.
Zurück zum Zitat Kintz P, Salomone A, Vincenti M (2015) Hair analysis in clinical and forensic toxicology. Elsevier/Academic Press, Amsterdam Kintz P, Salomone A, Vincenti M (2015) Hair analysis in clinical and forensic toxicology. Elsevier/Academic Press, Amsterdam
6.
Zurück zum Zitat Kintz P (2017) Hair analysis in forensic toxicology: an updated review with a special focus on pitfalls. Curr Pharm Design 23:1–7 Kintz P (2017) Hair analysis in forensic toxicology: an updated review with a special focus on pitfalls. Curr Pharm Design 23:1–7
7.
Zurück zum Zitat Musshoff F, Madea B (2016) Forensisch-toxikologische Eignungsuntersuchungen; Teil 1: Rechtliche Hintergründe und Durchführungsbestimmungen. Rechtsmedizin 26(2):149–165CrossRef Musshoff F, Madea B (2016) Forensisch-toxikologische Eignungsuntersuchungen; Teil 1: Rechtliche Hintergründe und Durchführungsbestimmungen. Rechtsmedizin 26(2):149–165CrossRef
8.
Zurück zum Zitat Musshoff F, Madea B (2016) Forensisch-toxikologische Eignungsuntersuchungen; Teil 2: Untersuchungsmaterialien und Anforderungen an die Analytik. Rechtsmedizin 26(3):237–250CrossRef Musshoff F, Madea B (2016) Forensisch-toxikologische Eignungsuntersuchungen; Teil 2: Untersuchungsmaterialien und Anforderungen an die Analytik. Rechtsmedizin 26(3):237–250CrossRef
9.
Zurück zum Zitat Cooper GA, Kronstrand R, Kintz P, Society of Hair Testing (2012) Society of Hair Testing guidelines for drug testing in hair. Forensic Sci Int 218(1–3):20–24CrossRef Cooper GA, Kronstrand R, Kintz P, Society of Hair Testing (2012) Society of Hair Testing guidelines for drug testing in hair. Forensic Sci Int 218(1–3):20–24CrossRef
10.
Zurück zum Zitat Salomone A, Tsanaclis L, Agius R, Kintz P, Baumgartner MR (2016) European guidelines for workplace drug and alcohol testing in hair. Drug Test Anal 8(10):996–1004CrossRef Salomone A, Tsanaclis L, Agius R, Kintz P, Baumgartner MR (2016) European guidelines for workplace drug and alcohol testing in hair. Drug Test Anal 8(10):996–1004CrossRef
11.
Zurück zum Zitat Schubert W, Dittmann V, Brenner-Hartmann J (2013) Beurteilungskriterien. Urteilsbildung in der Fahreignungsbegutachtung, 3. Aufl. Kirschbaum Verlag, Bonn Schubert W, Dittmann V, Brenner-Hartmann J (2013) Beurteilungskriterien. Urteilsbildung in der Fahreignungsbegutachtung, 3. Aufl. Kirschbaum Verlag, Bonn
12.
Zurück zum Zitat Pötsch L, Skopp G (2004) Inkorporation von Fremdsubstanzen in Haare. In: Madea B, Mußhoff F (Hrsg) Haaranalytik: Technik und Interpretation in Medizin und Recht. Deutscher Ärzte-Verlag, Köln, S 29–98 Pötsch L, Skopp G (2004) Inkorporation von Fremdsubstanzen in Haare. In: Madea B, Mußhoff F (Hrsg) Haaranalytik: Technik und Interpretation in Medizin und Recht. Deutscher Ärzte-Verlag, Köln, S 29–98
13.
Zurück zum Zitat Dussy F, Carson N, Hangartner S, Briellmann T (2014) Is one hair lock really representative? Drug Test Anal 6(Suppl 1):5–8CrossRef Dussy F, Carson N, Hangartner S, Briellmann T (2014) Is one hair lock really representative? Drug Test Anal 6(Suppl 1):5–8CrossRef
14.
Zurück zum Zitat Meier U, Briellmann T, Scheurer E, Dussy F (2017) Distribution pattern of ethyl glucuronide and caffeine concentrations over the scalp of a single person in a forensic context. Drug Test Anal 9(10):1594–1603CrossRef Meier U, Briellmann T, Scheurer E, Dussy F (2017) Distribution pattern of ethyl glucuronide and caffeine concentrations over the scalp of a single person in a forensic context. Drug Test Anal 9(10):1594–1603CrossRef
15.
Zurück zum Zitat Musshoff F (2017) Aktuelles zu Alkoholkonsummarkern in der Fahreignungsdiagnostik. ZVS 63(4):125–135 Musshoff F (2017) Aktuelles zu Alkoholkonsummarkern in der Fahreignungsdiagnostik. ZVS 63(4):125–135
16.
Zurück zum Zitat Brenner-Hartmann J, Graw M, Musshoff F (2016) Beurteilungskriterien. ZVS 62(3):58–59 Brenner-Hartmann J, Graw M, Musshoff F (2016) Beurteilungskriterien. ZVS 62(3):58–59
17.
Zurück zum Zitat Hoelzle C, Scheufler F, Uhl M, Sachs H, Thieme D (2008) Application of discriminant analysis to differentiate between incorporation of cocaine and its congeners into hair and contamination. Forensic Sci Int 176(1):13–18CrossRef Hoelzle C, Scheufler F, Uhl M, Sachs H, Thieme D (2008) Application of discriminant analysis to differentiate between incorporation of cocaine and its congeners into hair and contamination. Forensic Sci Int 176(1):13–18CrossRef
18.
Zurück zum Zitat Ropero-Miller JD, Huestis MA, Stout PR (2012) Cocaine analytes in human hair. Evaluation of concentration ratios in different cocaine sources, drug-user populations and surface-contaminated specimens. J Anal Toxicol 36(6):390–398CrossRef Ropero-Miller JD, Huestis MA, Stout PR (2012) Cocaine analytes in human hair. Evaluation of concentration ratios in different cocaine sources, drug-user populations and surface-contaminated specimens. J Anal Toxicol 36(6):390–398CrossRef
19.
Zurück zum Zitat Schaffer M, Cheng C‑C, Chao O, Hill V, Matsui P (2016) Analysis of cocaine and metabolites in hair: validation and application of measurement of hydroxycocaine metabolites as evidence of cocaine ingestion. Anal Bioanal Chem 408(8):2043–2054CrossRef Schaffer M, Cheng C‑C, Chao O, Hill V, Matsui P (2016) Analysis of cocaine and metabolites in hair: validation and application of measurement of hydroxycocaine metabolites as evidence of cocaine ingestion. Anal Bioanal Chem 408(8):2043–2054CrossRef
20.
Zurück zum Zitat Musshoff F, Thieme D, Schwarz G, Sachs H, Skopp G, Franz T (2018) Determination of hydroxy metabolites of cocaine in hair samples for proof of consumption. Drug Test Anal 10(4):681–688CrossRef Musshoff F, Thieme D, Schwarz G, Sachs H, Skopp G, Franz T (2018) Determination of hydroxy metabolites of cocaine in hair samples for proof of consumption. Drug Test Anal 10(4):681–688CrossRef
21.
Zurück zum Zitat Franz T, Scheufler F, Stein K, Uhl M, Dame T, Schwarz G, Sachs H, Skopp G, Musshoff F (2018) Determination of hydroxy metabolites of cocaine from hair samples and comparison with street cocaine samples. Forensic Sci Int 288:223–226CrossRef Franz T, Scheufler F, Stein K, Uhl M, Dame T, Schwarz G, Sachs H, Skopp G, Musshoff F (2018) Determination of hydroxy metabolites of cocaine from hair samples and comparison with street cocaine samples. Forensic Sci Int 288:223–226CrossRef
22.
Zurück zum Zitat Franz T, Skopp G, Schwarz G, Musshoff F (2018) Proof of active cannabis use comparing 11-hydroxy-∆9-tetrahydrocannabinol with 11-nor-9- carboxy-tetrahydrocannabinol concentrations. Drug Test Anal 10(10):1573–1578CrossRef Franz T, Skopp G, Schwarz G, Musshoff F (2018) Proof of active cannabis use comparing 11-hydroxy-∆9-tetrahydrocannabinol with 11-nor-9- carboxy-tetrahydrocannabinol concentrations. Drug Test Anal 10(10):1573–1578CrossRef
23.
Zurück zum Zitat Moosmann B, Roth N, Auwärter V (2015) Finding cannabinoids in hair does not prove cannabis consumption. Sci Rep 5:14906CrossRef Moosmann B, Roth N, Auwärter V (2015) Finding cannabinoids in hair does not prove cannabis consumption. Sci Rep 5:14906CrossRef
25.
Zurück zum Zitat Hill VA, Schaffer MI, Stowe GN (2016) Carboxy-THC in washed hair. Still the reliable indicator of marijuana ingestion. J Anal Toxicol 40(5):345–349CrossRef Hill VA, Schaffer MI, Stowe GN (2016) Carboxy-THC in washed hair. Still the reliable indicator of marijuana ingestion. J Anal Toxicol 40(5):345–349CrossRef
26.
Zurück zum Zitat Auwärter V, Wohlfarth A, Traber J, Thieme D, Weinmann W (2010) Hair analysis for ∆9-tetrahydrocannabinolic acid A—new insights into the mechanism of drug incorporation of cannabinoids into hair. Forensic Sci Int 196:10–13CrossRef Auwärter V, Wohlfarth A, Traber J, Thieme D, Weinmann W (2010) Hair analysis for ∆9-tetrahydrocannabinolic acid A—new insights into the mechanism of drug incorporation of cannabinoids into hair. Forensic Sci Int 196:10–13CrossRef
27.
Zurück zum Zitat Musshoff F, Graw M (2016) Dauerhafte Arzneimitteleinnahme – Frage nach Fahrsicherheit und Fahreignung – Teil II. Möglichkeiten eines analytischen Labors. Blutalkohol 53:333–346 Musshoff F, Graw M (2016) Dauerhafte Arzneimitteleinnahme – Frage nach Fahrsicherheit und Fahreignung – Teil II. Möglichkeiten eines analytischen Labors. Blutalkohol 53:333–346
28.
Zurück zum Zitat Wang X, Drummer OH (2015) Review: interpretation of drug presence in the hair of children. Forensic Sci Int 257:458–472CrossRef Wang X, Drummer OH (2015) Review: interpretation of drug presence in the hair of children. Forensic Sci Int 257:458–472CrossRef
29.
Zurück zum Zitat Kintz P, Ameline A, Eibel A, Gheddar L, Feisthauer E, Geraut A, Berthelon L, Farrugia A, Raul JS (2017) Interpretation of cannabis findings in the hair of very young children: mission impossible. Curr Pharm Biotechnol 18(10):791–795CrossRef Kintz P, Ameline A, Eibel A, Gheddar L, Feisthauer E, Geraut A, Berthelon L, Farrugia A, Raul JS (2017) Interpretation of cannabis findings in the hair of very young children: mission impossible. Curr Pharm Biotechnol 18(10):791–795CrossRef
30.
Zurück zum Zitat Sachs H (1995) Drogennachweis in Haaren. In: Kijewski H (Hrsg) Das Haar als Spur – Spur der Haare. Schmidt-Römhild, Lübeck, S 119–133 Sachs H (1995) Drogennachweis in Haaren. In: Kijewski H (Hrsg) Das Haar als Spur – Spur der Haare. Schmidt-Römhild, Lübeck, S 119–133
31.
Zurück zum Zitat Pianta A, Liniger B, Baumgartner MR (2013) Ethyl glucuronide in scalp and non-head hair: an intra-individual comparison. Alcohol Alcohol 48(3):295–302CrossRef Pianta A, Liniger B, Baumgartner MR (2013) Ethyl glucuronide in scalp and non-head hair: an intra-individual comparison. Alcohol Alcohol 48(3):295–302CrossRef
32.
Zurück zum Zitat Pragst F, Yegles M (2008) Determination of fatty acid ethyl esters (FAEE) and ethyl glucuronide (EtG) in hair: a promising way for retrospective detection of alcohol abuse during pregnancy? Ther Drug Monit 30(2):255–263CrossRef Pragst F, Yegles M (2008) Determination of fatty acid ethyl esters (FAEE) and ethyl glucuronide (EtG) in hair: a promising way for retrospective detection of alcohol abuse during pregnancy? Ther Drug Monit 30(2):255–263CrossRef
33.
Zurück zum Zitat Tsanaclis L, Kingston R, Wicks J (2009) Testing for alcohol use in hair. Is ethyl glucuronide (EtG) stable in hair? Ann Tox Anal 21(2):67–71CrossRef Tsanaclis L, Kingston R, Wicks J (2009) Testing for alcohol use in hair. Is ethyl glucuronide (EtG) stable in hair? Ann Tox Anal 21(2):67–71CrossRef
34.
Zurück zum Zitat Pragst F, Rothe M, Moench B, Hastedt M, Herre S, Simmert D (2010) Combined use of fatty acid ethyl esters and ethyl glucuronide in hair for diagnosis of alcohol abuse: interpretation and advantages. Forensic Sci Int 196(1–3):101–110CrossRef Pragst F, Rothe M, Moench B, Hastedt M, Herre S, Simmert D (2010) Combined use of fatty acid ethyl esters and ethyl glucuronide in hair for diagnosis of alcohol abuse: interpretation and advantages. Forensic Sci Int 196(1–3):101–110CrossRef
35.
Zurück zum Zitat Fosen JT, Høiseth G, Sempio C, Giarratana N, Enger A, Mørland J, Morini L (2019) Hair EtG: alterations in segment levels accompanying hair growth. Drug Test Anal 11(1):112-118CrossRef Fosen JT, Høiseth G, Sempio C, Giarratana N, Enger A, Mørland J, Morini L (2019) Hair EtG: alterations in segment levels accompanying hair growth. Drug Test Anal 11(1):112-118CrossRef
36.
Zurück zum Zitat Crunelle CL, Cappelle D, Yegles M, de Doncker M, Michielsen P, Dom G, van Nuijs ALN, Maudens KE, Covaci A, Neels H (2016) Ethyl glucuronide concentrations in hair: a controlled alcohol-dosing study in healthy volunteers. Anal Bioanal Chem 408(8):2019–2025CrossRef Crunelle CL, Cappelle D, Yegles M, de Doncker M, Michielsen P, Dom G, van Nuijs ALN, Maudens KE, Covaci A, Neels H (2016) Ethyl glucuronide concentrations in hair: a controlled alcohol-dosing study in healthy volunteers. Anal Bioanal Chem 408(8):2019–2025CrossRef
38.
Zurück zum Zitat Pirro V, Di Corcia D, Seganti F, Salomone A, Vincenti M (2013) Determination of ethyl glucuronide levels in hair for the assessment of alcohol abstinence. Forensic Sci Int 232(1–3):229–236CrossRef Pirro V, Di Corcia D, Seganti F, Salomone A, Vincenti M (2013) Determination of ethyl glucuronide levels in hair for the assessment of alcohol abstinence. Forensic Sci Int 232(1–3):229–236CrossRef
39.
Zurück zum Zitat Mueller A, Jungen H, Iwersen-Bergmann S, Raduenz L, Lezius S, Andresen-Streichert H (2016) Determination of ethyl glucuronide in human hair samples: A multivariate analysis of the impact of extraction conditions on quantitative results. Forensic Sci Int 271:43–48CrossRef Mueller A, Jungen H, Iwersen-Bergmann S, Raduenz L, Lezius S, Andresen-Streichert H (2016) Determination of ethyl glucuronide in human hair samples: A multivariate analysis of the impact of extraction conditions on quantitative results. Forensic Sci Int 271:43–48CrossRef
40.
Zurück zum Zitat Salomone A, Baumgartner MR, Lombardo T, Alladio E, Di Corcia D, Vincenti M (2016) Effects of various sample pretreatment procedures on ethyl glucuronide quantification in hair samples: comparison of positivity rates and appraisal of cut-off values. Forensic Sci Int 267:60–65CrossRef Salomone A, Baumgartner MR, Lombardo T, Alladio E, Di Corcia D, Vincenti M (2016) Effects of various sample pretreatment procedures on ethyl glucuronide quantification in hair samples: comparison of positivity rates and appraisal of cut-off values. Forensic Sci Int 267:60–65CrossRef
41.
Zurück zum Zitat Sporkert F, Kharbouche H, Augsburger MP, Klemm C, Baumgartner MR (2012) Positive EtG findings in hair as a result of a cosmetic treatment. Forensic Sci Int 218:97–100CrossRef Sporkert F, Kharbouche H, Augsburger MP, Klemm C, Baumgartner MR (2012) Positive EtG findings in hair as a result of a cosmetic treatment. Forensic Sci Int 218:97–100CrossRef
42.
Zurück zum Zitat Arndt T, Schrofel S, Stemmerich K (2013) Ethyl glucuronide identified in commercial hair tonics. Forensic Sci Int 231(1–3):195–198CrossRef Arndt T, Schrofel S, Stemmerich K (2013) Ethyl glucuronide identified in commercial hair tonics. Forensic Sci Int 231(1–3):195–198CrossRef
43.
Zurück zum Zitat Crunelle CL, Yegles M, de Doncker M, Dom G, Cappelle D, Maudens KE, van Nuijs ALN, Covaci A, Neels H (2015) Influence of repeated permanent coloring and bleaching on ethyl glucuronide concentrations in hair from alcohol-dependent patients. Forensic Sci Int 247:18–22CrossRef Crunelle CL, Yegles M, de Doncker M, Dom G, Cappelle D, Maudens KE, van Nuijs ALN, Covaci A, Neels H (2015) Influence of repeated permanent coloring and bleaching on ethyl glucuronide concentrations in hair from alcohol-dependent patients. Forensic Sci Int 247:18–22CrossRef
44.
Zurück zum Zitat Binz TM, Baumgartner MR, Kraemer T (2014) The influence of cleansing shampoos on ethyl glucuronide concentration in hair analyzed with an optimized and validated LC-MS/MS method. Forensic Sci Int 244:20–24CrossRef Binz TM, Baumgartner MR, Kraemer T (2014) The influence of cleansing shampoos on ethyl glucuronide concentration in hair analyzed with an optimized and validated LC-MS/MS method. Forensic Sci Int 244:20–24CrossRef
45.
Zurück zum Zitat Pragst F, Auwaerter V, Sporkert F, Spiegel K (2001) Analysis of fatty acid ethyl esters in hair as possible markers of chronically elevated alcohol consumption by headspace solid-phase microextraction (HS-SPME) and gas chromatograph—mass spectrometry (GC-MS). Forensic Sci Int 121:76–88CrossRef Pragst F, Auwaerter V, Sporkert F, Spiegel K (2001) Analysis of fatty acid ethyl esters in hair as possible markers of chronically elevated alcohol consumption by headspace solid-phase microextraction (HS-SPME) and gas chromatograph—mass spectrometry (GC-MS). Forensic Sci Int 121:76–88CrossRef
46.
Zurück zum Zitat Albermann ME, Musshoff F, Madea B (2011) Comparison of ethyl glucuronide (EtG) and fatty acid ethyl esters (FAEEs) concentrations in hair for testing abstinence. Anal Bioanal Chem 400(1):175–181CrossRef Albermann ME, Musshoff F, Madea B (2011) Comparison of ethyl glucuronide (EtG) and fatty acid ethyl esters (FAEEs) concentrations in hair for testing abstinence. Anal Bioanal Chem 400(1):175–181CrossRef
47.
Zurück zum Zitat Hartwig S, Auwärter V, Pragst F (2003) Effect of hair care and hair cosmetics on the concentrations of fatty acid ethyl esters in hair as markers of chronically elevated alcohol consumption. Forensic Sci Int 131(2–3):90–97CrossRef Hartwig S, Auwärter V, Pragst F (2003) Effect of hair care and hair cosmetics on the concentrations of fatty acid ethyl esters in hair as markers of chronically elevated alcohol consumption. Forensic Sci Int 131(2–3):90–97CrossRef
48.
Zurück zum Zitat Gareri J, Appenzeller B, Walasek P, Koren G (2011) Impact of hair-care products on FAEE hair concentrations in substance abuse monitoring. Anal Bioanal Chem 400(1):183–188CrossRef Gareri J, Appenzeller B, Walasek P, Koren G (2011) Impact of hair-care products on FAEE hair concentrations in substance abuse monitoring. Anal Bioanal Chem 400(1):183–188CrossRef
49.
Zurück zum Zitat Kulaga V, Velazquez-Armenta Y, Aleksa K, Vergee Z, Koren G (2009) The effect of hair pigment on the incorporation of fatty acid ethyl esters (FAEE). Alcohol Alcohol 44(3):287–292CrossRef Kulaga V, Velazquez-Armenta Y, Aleksa K, Vergee Z, Koren G (2009) The effect of hair pigment on the incorporation of fatty acid ethyl esters (FAEE). Alcohol Alcohol 44(3):287–292CrossRef
50.
Zurück zum Zitat Suesse S, Pragst F, Mieczkowski T, Selavka CM, Elian A, Sachs H, Hastedt M, Rothe M, Campbell J (2012) Practical experiences in application of hair fatty acid ethyl esters and ethyl glucuronide for detection of chronic alcohol abuse in forensic cases. Forensic Sci Int 218(1–3):82–91CrossRef Suesse S, Pragst F, Mieczkowski T, Selavka CM, Elian A, Sachs H, Hastedt M, Rothe M, Campbell J (2012) Practical experiences in application of hair fatty acid ethyl esters and ethyl glucuronide for detection of chronic alcohol abuse in forensic cases. Forensic Sci Int 218(1–3):82–91CrossRef
53.
Zurück zum Zitat Suesse S, Blueml M, Pragst F (2015) Effect of the analyzed hair length on fatty acid ethyl ester (FAEE) concentrations in hair—is there congruence of cut-offs for 0–3 and 0–6 cm hair segments? Forensic Sci Int 249:1–5CrossRef Suesse S, Blueml M, Pragst F (2015) Effect of the analyzed hair length on fatty acid ethyl ester (FAEE) concentrations in hair—is there congruence of cut-offs for 0–3 and 0–6 cm hair segments? Forensic Sci Int 249:1–5CrossRef
54.
Zurück zum Zitat Busardò FP, Pichini S, Zaami S, Pacifici R, Kintz P (2018) Hair testing of GHB: an everlasting issue in forensic toxicology. Clin Chem Lab Med 56(2):198–208CrossRef Busardò FP, Pichini S, Zaami S, Pacifici R, Kintz P (2018) Hair testing of GHB: an everlasting issue in forensic toxicology. Clin Chem Lab Med 56(2):198–208CrossRef
55.
Zurück zum Zitat Kintz P (2016) A novel approach to document single exposure to GHB: hair analysis after sweat contamination. J Anal Toxicol 40(7):563–564CrossRef Kintz P (2016) A novel approach to document single exposure to GHB: hair analysis after sweat contamination. J Anal Toxicol 40(7):563–564CrossRef
56.
Zurück zum Zitat Boumba VA, Di Rago M, Peka M, Drummer OH, Gerostamoulos D (2017) The analysis of 132 novel psychoactive substances in human hair using a single step extraction by tandem LC/MS. Forensic Sci Int 279:192–202CrossRef Boumba VA, Di Rago M, Peka M, Drummer OH, Gerostamoulos D (2017) The analysis of 132 novel psychoactive substances in human hair using a single step extraction by tandem LC/MS. Forensic Sci Int 279:192–202CrossRef
57.
Zurück zum Zitat Gerostamoulos D, Elliott S, Walls HC, Peters FT, Lynch M, Drummer OH (2016) To measure or not to measure? That is the NPS question. J Anal Toxicol 40(4):318–320CrossRef Gerostamoulos D, Elliott S, Walls HC, Peters FT, Lynch M, Drummer OH (2016) To measure or not to measure? That is the NPS question. J Anal Toxicol 40(4):318–320CrossRef
58.
Zurück zum Zitat Franz F, Angerer V, Hermanns-Clausen M, Auwärter V, Moosmann B (2016) Metabolites of synthetic cannabinoids in hair—proof of consumption or false friends for interpretation? Anal Bioanal Chem 408(13):3445–3452CrossRef Franz F, Angerer V, Hermanns-Clausen M, Auwärter V, Moosmann B (2016) Metabolites of synthetic cannabinoids in hair—proof of consumption or false friends for interpretation? Anal Bioanal Chem 408(13):3445–3452CrossRef
59.
Zurück zum Zitat Thieme D, Sachs H (2007) Examination of a long-term clozapine administration by high resolution segmental hair analysis. Forensic Sci Int 166(2–3):110–114CrossRef Thieme D, Sachs H (2007) Examination of a long-term clozapine administration by high resolution segmental hair analysis. Forensic Sci Int 166(2–3):110–114CrossRef
60.
Zurück zum Zitat Thieme D, Baumer C, Sachs H, Teske J (2013) Screening and long-term retrospection for psychoactive drugs in presumptive drug-facilitated crimes using segmented single hairs. Drug Test Anal 5(9–10):736–740CrossRef Thieme D, Baumer C, Sachs H, Teske J (2013) Screening and long-term retrospection for psychoactive drugs in presumptive drug-facilitated crimes using segmented single hairs. Drug Test Anal 5(9–10):736–740CrossRef
61.
Zurück zum Zitat Allibe N, Kintz P, Faure A, Paysant F, Michard-Lenoir AP, Stanke-Labesque F, Scolan V, Eysseric-Guerin H (2017) Interest of single hair analysis to document drug exposure: literature review and a case report involving zuclopenthixol. Curr Pharm Des 23(36):5502–5510PubMed Allibe N, Kintz P, Faure A, Paysant F, Michard-Lenoir AP, Stanke-Labesque F, Scolan V, Eysseric-Guerin H (2017) Interest of single hair analysis to document drug exposure: literature review and a case report involving zuclopenthixol. Curr Pharm Des 23(36):5502–5510PubMed
Metadaten
Titel
Aktuelles zur forensisch-toxikologischen Haaranalytik
verfasst von
Prof. Dr. F. Musshoff
Publikationsdatum
21.03.2019
Verlag
Springer Medizin
Erschienen in
Rechtsmedizin / Ausgabe 2/2019
Print ISSN: 0937-9819
Elektronische ISSN: 1434-5196
DOI
https://doi.org/10.1007/s00194-019-0309-3

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