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31.07.2018 | Forensische Alkohologie und Toxikologie | CME

Propofol – Abhängigkeitspotenzial und forensische Relevanz

verfasst von: A. Maas, D. Lohr, C. Maier, B. Madea

Erschienen in: Rechtsmedizin | Ausgabe 5/2018

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Zusammenfassung

Propofol ist ein weltweit sehr häufig eingesetztes Hypnotikum, das neben seiner Eignung für den medizinischen Einsatz auch ein Abhängigkeitspotenzial aufweist. Spätestens seit dem propofolassoziierten Tod des Sängers Michael Jackson ist die Substanz auch der breiten Öffentlichkeit bekannt. Besonders häufig ist der Missbrauch bei Medizinern und medizinischem Fachpersonal. Aufgrund des engen Fensters zwischen den gewünschten Effekten und einer potenziell lebensbedrohlichen Intoxikation ist der missbräuchliche Konsum von Propofol jedoch auch für Mediziner äußerst riskant. Die hohe Letalitätsrate, die innerhalb des ersten Jahres nach Beginn der Abhängigkeit beobachtet wird, verdeutlicht das Risiko, das mit dieser Suchterkrankung einhergeht. Entsprechend ist es umso wichtiger, dass ein solcher Missbrauch frühzeitig erkannt wird. Der Nachweis eines chronischen Propofolmissbrauchs kann mithilfe einer validen Haaranalytik erfolgen.

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Titel: Propofol – Abhängigkeitspotenzial und forensische Relevanz
verfasst von: A. Maas
D. Lohr
C. Maier
B. Madea
Publikationsdatum: 31.07.2018
Verlag: Springer Medizin
Schlagwörter: Forensische Alkohologie und Toxikologie
Störungen durch psychotrope Substanzen
Substanzabusus und Sucht
Erschienen in: Rechtsmedizin / Ausgabe 5/2018
Print ISSN: 0937-9819
Elektronische ISSN: 1434-5196
DOI: https://doi.org/10.1007/s00194-018-0263-5

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