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Current Behavioral Neuroscience Reports

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01.06.2019 | Psychosis (A Ahmed, Section Editor)

Frustrative Non-reward and Lab-Based Paradigms for Advancing the Study of Aggression in Persons with Psychosis

verfasst von: Jill Del Pozzo, Christina Athineos, Taylor Zar, Lisa N. Cruz, Christopher M. King

Erschienen in: Current Behavioral Neuroscience Reports | Ausgabe 2/2019

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Abstract

Purpose of Review

Prior research and assessment of aggression in schizophrenia and other psychotic conditions has focused on one or two levels of measurement (third-party observation and self-report) identified by the NIMH Research Domain Criteria (RDoC), while frequently neglecting a third (laboratory behavioral paradigms). We review aggression in psychosis using the RDoC conceptualization of frustrative non-reward; describe how lab-based behavioral paradigms, particularly, the Point Subtraction Aggression Paradigm (PSAP), can help to better understand aggression in individuals with psychosis; and suggest directions for future research.

Recent Findings

Many studies of violence in psychosis focus on field observations of behavior and self-report. However, laboratory behavioral paradigms such as the PSAP, which have not been widely adopted, hold conceptual promise for the study of aggression in schizophrenia.

Summary

The RDoC represent a neurobehavioral approach for advancing behavioral health research that recommends multilevel investigations to include laboratory behavioral paradigms. The PSAP is one such behavioral measure with particular relevance to a frustrative non-reward conceptualization of aggression. The PSAP and its adaptations offer a promising methodology for future research of aggression in schizophrenia and other psychotic conditions. The method may likewise prove useful in individual cases, to enhance the incremental validity of violence risk assessment.

• Silverstein SM, Del Pozzo J, Roché M, Boyle D, Miskimen T. Schizophrenia and violence: realities and recommendations. Crime Psychol Rev. 2015;1(1):21–42. https://doi.org/10.1080/23744006.2015 1033154 Addresses specific schizophrenia and violence risk characteristics.CrossRef

Witt K, Van Dorn R, Fazel S. Risk factors for violence in psychosis: systematic review and meta-regression analysis of 110 studies. PLoS One. 2013;8(2):e55942. https://doi.org/10.1371/journal.pone.0055942.CrossRefPubMedPubMedCentral

Fazel S, Gulati G, Linsell L, Geddes JR, Grann M. Schizophrenia and violence: systematic review and meta-analysis. PLoS Med. 2009;6(8):e1000120. https://doi.org/10.1371/journal.pmed.1000120.CrossRefPubMedPubMedCentral

Fazel S, Långström N, Hjern A, Grann M, Lichtenstein P. Schizophrenia, substance abuse, and violent crime. Jama. 2009;301(19):2016–23. https://doi.org/10.1001/jama.2009.675.CrossRefPubMedPubMedCentral

Swanson JW, Holzer IIICE, Ganju VK, Jono RT. Violence and psychiatric disorder in the community: evidence from the Epidemiologic Catchment Area surveys. Psychiatr Serv. 1990;41(7):761–70. https://doi.org/10.1176/ps.41.7.761.CrossRef

Volavka J. Violence in schizophrenia and bipolar disorder. Psychiatr Danub. 2013;25(1):0–33.

•• Hoptman MJ. Impulsivity and aggression in schizophrenia: a neural circuitry perspective with implications for treatment. CNS Spectrums. 2015;20(3):280–6. https://doi.org/10.1017/S1092852915000206 Discusses the neural circuitry associated with impulsivity and aggression in schizophrenia, with an emphasis on implications for treatment. CrossRefPubMedPubMedCentral

Cherek DR. Effects of smoking different doses of nicotine on human aggressive behavior. Psychopharmacol [Internet]. 1981;75(4):339–45. https://doi.org/10.1007/BF00435849.CrossRef

•• Watson D, Stanton K, Clark LA. Self-report indicators of negative valence constructs within the research domain criteria (RDoC): a critical review. J Affect Disord. 2017;1(216):58–69. https://doi.org/10.1016/j.jad.2016.09.065 Reviews the negative valence systems construct within RDoC.CrossRef

10.

Blair RJ, White SF, Meffert H, Hwang S. Disruptive behavior disorders: taking an RDoC (ish) approach. In: The neurobiology of childhood. Berlin, Heidelberg: Springer; 2013. p. 319–36.CrossRef

11.

•• Lindenmayer JP. The NIMH research domain criteria initiative and comorbidity in schizophrenia: research implications. Psychiatr Ann. 2018;48(12):547–51. https://doi.org/10.3928/00485713-20181108-01 Presents the potential advantage of using the RDoC in the study of behavioral domains within schizophrenia. CrossRef

12.

• Gatzke-Kopp LM, Willner CJ, Jetha MK, Abenavoli RM, DuPuis D, Segalowitz SJ. How does reactivity to frustrative non-reward increase risk for externalizing symptoms? Int J Psychophysiol. 2015;98(2):300–9. https://doi.org/10.1016/j.ijpsycho.2015.04.018 Highlights the frustrative non-reward construct and how excessive anger in response to frustration characterizes multiple forms of externalizing psychopathology. CrossRefPubMedPubMedCentral

13.

Dollard J, Dood L, Miller N, Mowrer O, Sears R. Frustration and aggression. New Haven: Yale University Press; 1939.CrossRef

14.

Berkowitz L. Aggression: a social psychological analysis. New York: McGraw-Hill; 1963.

15.

•• Sukhodolsky DG, Smith SD, McCauley SA, Ibrahim K, Piasecka JB. Behavioral interventions for anger, irritability, and aggression in children and adolescents. Journal of child and adolescent psychopharmacology. 2016;26(1):58–64. https://doi.org/10.1089/cap.2015.0120 Anger, irritability, and aggression within frustrative non-reward. CrossRefPubMedPubMedCentral

16.

Dixon MJ, MacLaren V, Jarick M, Fugelsang JA, Harrigan KA. The frustrating effects of just missing the jackpot: slot machine near-misses trigger large skin conductance responses, but no post- reinforcement pauses. J Gambl Stud. 2013;29:661–4. https://doi.org/10.1007/s10899-012-9333-x.CrossRefPubMed

17.

Hamon-Jones C, Schmeichel BJ, Mennitt E, Harmon-Jones E. The expression of determination: similarities between anger and approach-related positive affect. J Pers Soc Psychol. 2011;100:172–81. https://doi.org/10.1037/a0020966.CrossRef

18.

Wehring HJ, Carpenter WT. Violence and schizophrenia. Schizophr Bull. 2011;37:877–8. https://doi.org/10.1093/schbul/sbr094.CrossRefPubMedPubMedCentral

19.

Volavka J Neurobiology of violence. American Psychiatric Pub; 2008.

20.

McEvoy JP. The costs of schizophrenia. J Clin Psychiatry. 2007;68:4–7.CrossRef

21.

Ferriman A. The stigma of schizophrenia. BMJ. 2000;320(7233):522. https://doi.org/10.1136/bmj.320.7233.522.CrossRefPubMedPubMedCentral

22.

Link BG, Phelan JC, Bresnahan M, Stueve A, Pescosolido BA. Public conceptions of mental illness: labels, causes, dangerousness, and social distance. Am J Public Health. 1999;89(9):1328–33. https://doi.org/10.2105/AJPH.89.9.1328.CrossRefPubMedPubMedCentral

23.

Van Dorn RA, Swanson JW, Elbogen EB, Swartz MS. A comparison of stigmatizing attitudes toward persons with schizophrenia in four stakeholder groups: perceived likelihood of violence and desire for social distance. Psychiatry: Interpersonal and Biological Processes. 2005;68(2):152–63. https://doi.org/10.1521/psyc.2005.68.2.152.CrossRef

24.

Swanson JW, Swartz MS, Van Dorn RA, Elbogen EB, Wagner HR, Rosenheck RA, et al. A national study of violent behavior in persons with schizophrenia. Arch Gen Psychiatry. 2006;63(5):490–9. https://doi.org/10.1001/archpsyc.63.5.490.CrossRefPubMed

25.

Volavka J, Swanson J. Violent behavior in mental illness: the role of substance abuse. JaMa. 2010;304(5):563–4. https://doi.org/10.1001/jama.2010.1097.CrossRefPubMedPubMedCentral

26.

Wallace C, Mullen PE, Burgess P. Criminal offending in schizophrenia over a 25-year period marked by deinstitutionalization and increasing prevalence of comorbid substance use disorders. Am J Psychiatr. 2004;161(4):716–27. https://doi.org/10.1176/appi.ajp.161.4.716.CrossRefPubMed

27.

Joyal CC, Dubreucq JL, Gendron C, Millaud F. Major mental disorders and violence: a critical update. Curr Psychiatr Rev. 2007;3(1):33–50. https://doi.org/10.2174/157340007779815628.CrossRef

28.

Douglas KS, Guy LS, Hart SD. Psychosis as a risk factor for violence to others: a meta-analysis. Psychol Bull. 2009;135(5):679. https://doi.org/10.1037/a0016311.CrossRefPubMed

29.

•• Volavka J. Triggering violence in psychosis. JAMA Psychiatry. 2016;73(8):769–70. https://doi.org/10.1001/jamapsychiatry.2016.1348 Discusses the modifiable risk factors for violence in psychosis including impulsivity. CrossRefPubMed

30.

Monahan J, Steadman HJ, Silver E, Appelbaum PS, Robbins PC, Mulvey EP, Roth LH, Grisso T, Banks S. Rethinking risk assessment: the MacArthur study of mental disorder and violence. Oxford University Press; 2001.

31.

Arce E, Santisteban C. Impulsivity: a review. Psicothema. 2006;18(2):213–20 https://www.redalyc.org/html/727/72718208/. Accessed 12 Feb 2019.

32.

Barratt E, Stanford M, Kent T, Alan F. Neuropsychological and cognitive psychophysiological substrates of impulsive aggression. Biol Psychiatry. 1998;41(10):1045–61. https://doi.org/10.1016/S0006-3223(96)00175-8.CrossRef

33.

Walker J, Bright J. Cognitive therapy for violence: reaching the parts that anger management doesn’t reach. J Forensic Psychiatry Psychol. 2009;20(2):174–201. https://doi.org/10.1080/14789940701656832.CrossRef

34.

Broderick C, Azizian A, Kornbluh R, Warburton K. Prevalence of physical violence in a forensic psychiatric hospital system during 2011–2013: patient assaults, staff assaults, and repeatedly violent patients. CNS Spectrums. 2015;20(3):319–30. https://doi.org/10.1017/S1092852915000188.CrossRefPubMed

35.

Chang WC, Chan SSI, Hui CLM, Chan SKW, Lee EHM, Chen EYH. Prevalence and risk factors for violent behavior in young people presenting with first episode psychosis in Hong Kong: a 3-year follow-up study. Aust N Z J Psychiatry. 2015;49(10):914–22. https://doi.org/10.1177/0004867415603130.CrossRefPubMed

36.

•• Knezevic V, Mitrovic D, Drezgic-Vukic S, Knezevic J, Ivezic A, Siladji-Mladenovic D, et al. Prevalence and correlates of aggression and hostility in hospitalized schizophrenic patients. J. Interpers Violence. 2017;32(2):151–63. https://doi.org/10.1177/0886260515585537 Identifies the incidence as well as clinical and socio-demographic correlates of aggression in hospitalized schizophrenic patients. CrossRefPubMed

37.

Nazmie I, Nebi M, Zylfije H, Bekim H. Poor executive functioning associated with the risk of aggressive behavior recidivism in the forensic community in schizophrenic patients. Int J Biomed. 2013;3(2):94–9.

38.

Krakowski M, Czobor P. The denial of aggression in violent patients with schizophrenia. Schizophr Res. 2012;141(2–3):228–33. https://doi.org/10.1016/j.schres.2012.08.037.CrossRefPubMed

39.

•• Ahmed A, Richardson J, Buckner A, Romanoff S, Feder M, Oragunye N, et al. Do cognitive deficits predict negative emotionality and aggression in schizophrenia? Psychiatry Res. 2018;259:350–7 Describes how cognitive deficits may contribute to aggression in schizophrenia. CrossRef

40.

•• Hundozi Z, Ibishi N, Musliu N. Cognitive functions and recidivism of aggressive behavior in schizophrenic inpatients at Forensic Unit Clinic of Psychiatry in Kosovo. Cogent Psychol. 2016; 3(1). https://doi.org/10.1080/23311908.2016.1233650 How schizophrenia is associated with elevated risk of aggressive behavior and poor cognitive performance.

41.

Lipszyc J, Schachar R. Inhibitory control and psychopathology: a meta-analysis of studies using the stop signal task. J Int Neuropsychol Soc. 2010;16(6):1064–76.CrossRef

42.

Wright L, Lipszyc J, Dupuis A, Thayapararajah SW, Schachar R, Goodman S. Response inhibition and psychopathology: a meta-analysis of go/no-go task performance. J Abnorm Psychol. 2014;123(2):429–39.CrossRef

43.

• Taylor SP. Aggressive behavior and physiological arousal as a function of provocation and the tendency to inhibit aggression. J Pers. 1967;35(2):297–310. https://doi.org/10.1111/j.1467-6494.1967.tb01430x Seminal article on the TAP paradigm. CrossRefPubMed

44.

Skibsted AP, Cunha-Bang SD, Carré JM, Hansen AE, Beliveau V, Knudsen GM, et al. Aggression-related brain function assessed with the Point Subtraction Aggression Paradigm in fMRI. Aggress Behav. 2017;43(6):601–10. https://doi.org/10.1002/ab.21718.CrossRefPubMed

45.

Goldsmith HH, Buss AH, Plomin R, Rothbart MK, Thomas A, Chess S, et al. Roundtable: what is temperament? Four approaches. Child Dev. 1987;58:505–29. https://doi.org/10.2307/1130527.CrossRefPubMed

46.

Rothbart MK. Temperament in childhood: a framework. In: Kohnstamm GA, Bates JE, Rothbart MK, editors. Temperament in Childhood. Chicester, U.K: Wiley; 1989. p. 59–73.

47.

Rothbart MK, Bates JE. Temperament. In: Eisenberg N, editor. Handbook of child psychology: social, emotional, & personality development. New York: Wiley; 1998. p. 105–76.

48.

Gagne JR, Van Hulle CA, Aksan N, Essex MJ, Goldsmith HH. Deriving childhood temperament measures from emotion-eliciting behavioral episodes: scale construction and initial validation. Psychol Assess. 2011;23(2):337. https://doi.org/10.1037/a0021746.CrossRefPubMedPubMedCentral

49.

Caspi A, Roberts BW, Shiner RL. Personality development: stability and change. Annu Rev Psychol. 2005;56:453–84. https://doi.org/10.1146/annurev.psych.55.090902.141913.CrossRefPubMed

50.

Goldsmith HH, Lemery KS, Essex MJ. Temperament as a liability factor for childhood behavioral disorders: the concept of liability. In: DiLalla LF, editor. Behavior genetics principles: perspectives in development, personality, and psychopathology. Washington, DC: American Psychological Association; 2004. p. 19–39.

51.

Shankman SA, Klein DN, Torpey DC, Olino TM, Dyson MW, Kim J, et al. Do positive and negative temperament traits interact in predicting risk for depression? A resting EEG study of 329 preschoolers. Dev Psychopathol. 2011;23(2):551–62. https://doi.org/10.1017/S0954579411000022.CrossRefPubMedPubMedCentral

52.

• McCloskey MS, Berman ME, Coccaro EF. Providing an escape option reduces retaliatory aggression. Aggress Behav. 2005;31(3):228–37 doi.org/10.1002/ab.20084 Examines whether providing an explicit means to escape future attacks by a provocative fictitious participant reduces retaliatory aggression using the PSAP.CrossRef

53.

Björkly S. Psychotic symptoms and violence toward others – a literature review of some preliminary findings. Part 1. Delusions. Aggress Violent Behav. 2002;7(6):617–31. https://doi.org/10.1016/S1359-1789(01)00049-0.CrossRef

54.

Walsh E, Buchanan A, Fahy T. Violence and schizophrenia: examining the evidence. Brit J Psychiatry. 2002;180(6):490–5. https://doi.org/10.1192/bjp.180.6.490.CrossRef

55.

Frésan A, Apiquian R, Fuente-Sandoval C, De La Löyzaga C, García-Anaya M, Meyenberg N, et al. Violent behavior in schizophrenic patients: relationship with clinical symptoms. Aggress Behav. 2005;31(6):511–20. https://doi.org/10.1002/ab.20060.CrossRef

56.

van Dongen JDM, Buck NML, van Marle HJC. The role of ideational distress in the relation between persecutory ideations and reactive aggression. Crim Behav Ment Health. 2012;22(5):350–9. https://doi.org/10.1002/cbm.1836.CrossRefPubMed

57.

van Dongen JDM, Buck NML, Kool AM, Van Marle HJC. Psychometric evaluation of the Dutch persecutory ideation questionnaire (PIQ) and its relation to aggression. Personal Individ Differ. 2011;51(4):527–31. https://doi.org/10.1016/j.paid.2011.05.014.CrossRef

58.

Freeman D, Garety PA, Kuipers E, Fowler D, Bebbington PE, Dunn G. Acting on persecutory delusions: the importance of safety seeking. Behav Res Ther. 2007;45(1):89–99. https://doi.org/10.1016/j.brat.2006.01.014.CrossRefPubMed

59.

Geniole SN, Carré JM, McCormick CM. State, not trait, neuroendocrine function predicts costly reactive aggression in men after social exclusion and inclusion. Biol Psychol. 2011;87(1):137–45. https://doi.org/10.1016/j.biopsycho.2011.02.020.CrossRefPubMed

60.

Pinto DG, Maltby J, Wood AM, Day L. A behavioral test of Horney’s linkage between authenticity and aggression: people living authentically are less-likely to respond aggressively in unfair situations. Personal Individ Differ. 2012;52(1):41–4. https://doi.org/10.1016/j.paid.2011.08.023.CrossRef

61.

Cima M, Raine A. Distinct characteristics of psychopathy relate to different subtypes of aggression. Personal Individ Differ. 2009;47(8):835–40. https://doi.org/10.1016/j.paid.2009.06.031.CrossRef

62.

Sanfey AG, Rilling JK, Aronson JA, Nystrom LE, Cohen JD. The neural basis of economic decision-making in the ultimatum game. Science. 2003;300(5626):1755–8. https://doi.org/10.1126/science.1082976.CrossRefPubMed

63.

Crockett MJ, Apergis-Schoute A, Herrmann B, Lieberman MD, Müller U, Robbins TW, et al. Serotonin modulates striatal responses to fairness and retaliation in humans. J Neurosci. 2013;33(8):3505–13. https://doi.org/10.1523/JNEUROSCI.2761-12.2013.CrossRefPubMedPubMedCentral

64.

Carré JM, Gilchrist JD, Morrissey MD, McCormick CM. Motivational and situational factors and the relationship between testosterone dynamics and human aggression during competition. Biol Psychol. 2010;84(2):346–53. https://doi.org/10.1016/j.biopsycho.2010.04.001.CrossRefPubMed

65.

•• Geniole SN, MacDonell ET, McCormick CM. The Point Subtraction Aggression Paradigm as a laboratory tool for investigating the neuroendocrinology of aggression and competition. Horm Behav. 2017;92:103–16. https://doi.org/10.1016/j.yhbeh.2016.04.006 Compares and contrasts the PSAP to other aggression measures. CrossRefPubMed

66.

• Cherek DR, Pietras CJ, Lane SD. Laboratory measures: Point Subtraction Aggression Paradigm (PSAP). In: Coccaro E, editor. Aggression: assessment and treatment. New York: Marcel Dekker; 2003. p. 215–28. Provocation and retaliation in aggression using the PSAP. CrossRef

67.

Lieving LM, Cherek DR, Lane SD, Tcheremissine OV, Nouvion SO. Effects of acute tiagabine administration on aggressive responses of adult male parolees. J Psychopharmacol. 2008;22(2):144–52. https://doi.org/10.1177/0269881107078489.CrossRefPubMed

68.

Tcheremissine OV, Lane SD, Lieving LM, Rhoades HM, Nouvion S, Cherek DR. Individual differences in aggressive responding to intravenous flumazenil administration in adult male parolees. J Psychopharmacol. 2015;19(6):640–6. https://doi.org/10.1177/0269881105056532.CrossRef

69.

Coccaro EF, Berman ME, Kavoussi RJ. Assessment of life history of aggression: development and psychometric characteristics. Psychiatry Res. 1997;73(3):147–57. https://doi.org/10.1016/S0165-1781(97)00119-4.CrossRefPubMed

70.

Golomb BA, Cortez-Perez M, Jaworski BA, Mednick S, Dimsdale J. Point Subtraction Aggression Paradigm: validity of a brief schedule of use. Violence Vict. 2007;22(1):95–103. https://doi.org/10.1891/vv-v22i1a006.CrossRefPubMed

71.

• McCloskey MS, New AS, Siever LJ, Goodman M, Koenigsberg HW, Flory JD, et al. Evaluation of behavioral impulsivity and aggression tasks as endophenotypes for borderline personality disorder. J Psychiatr Res. 2009;43(12):1036–48. https://doi.org/10.1016/j.jpsychires.2009.01.002 Evaluated the PSAP as a behavioral measure of aggression and impulsivity. CrossRefPubMedPubMedCentral

72.

Cherek DR, Moeller FG, Dougherty DM, Rhoades H. Studies of violent and nonviolent male parolees: II. Laboratory and psychometric measurements of impulsivity. Biol Psychiatry. 1997;42(5):523–9. https://doi.org/10.1016/S0006-3223(96)00426-X.CrossRef

73.

Cherek DR, Lane SD, Dougherty DM, Moeller FG, White S. Laboratory and questionnaire measures of aggression among female parolees with violent or nonviolent histories. Aggress Behav. 2000;26(4):291–307. https://doi.org/10.1002/1098-2337(2000)26:4<291::AID-AB2>3.0.CO;2–9.CrossRef

74.

Moeller FG, Dougherty DM, Rustin T, Swann AC, Allen TJ, Shah N, et al. Antisocial personality disorder and aggression in recently abstinent cocaine dependent subjects. Drug Alcohol Depend. 1997;44(2–3):175–82. https://doi.org/10.1016/S0376-8716(96)01335-X.CrossRefPubMed

75.

New AS, Hazlett EA, Newmark RE, Zhang J, Triebwasser J, Meyerson D, et al. Laboratory induced aggression: a PET study of aggressive individuals with borderline personality disorder. Biol Psychiatry. 2009;66(12):1107–14. https://doi.org/10.1016/j.biopsych.2009.07.015.CrossRefPubMedPubMedCentral

76.

Carré JM, McCormick CM. Aggressive behavior and change in salivary testosterone concentrations predict willingness to engage in a competitive task. Horm Behav. 2008;54:403–9. https://doi.org/10.1016/j.yhbeh.2008.04.008.CrossRefPubMed

77.

Bailly MD, King AR. Trait modulation of alcohol-induced laboratory aggression. Psychiatry Res. 2006;142(2–3):129–38. https://doi.org/10.1016/j.psychres.2005.10.015.CrossRefPubMed

78.

Gowin JL, Green CE, Alcorn IIIJL, Swann AC, Moeller FG, Lane SD. The role of cortisol and psychopathy in the cycle of violence. Psychopharmacol. 2013;227(4):661–72. https://doi.org/10.1007/s00213-013-2992-1.CrossRef

79.

Cote KA, McCormick CM, Geniole SN, Renn RP, MacAulay SD. Sleep deprivation lowers reactive aggression and testosterone in men. Biol Psychol. 2013;92(2):249–56. https://doi.org/10.1016/j.biopsycho.2012.09.011.CrossRefPubMed

80.

Sumner JA, Powers A, Jovanovic T, Koenen KC. Genetic influences on the neural and physiological bases of acute threat: a research domain criteria (RDoC) perspective. Am J Med Genet B Neuropsychiatr Genet. 2016;171(1):44–64.CrossRef

81.

Mandal MK, Pandey R, Prasad AB. Facial expressions of emotions and schizophrenia: a review. Schizophr Bull. 1998;24(3):399–412.CrossRef

82.

Kohler CG, Turner TH, Bilker WB, Brensinger CM, Siegel SJ, Kanes SJ, et al. Facial emotion recognition in schizophrenia: intensity effects and error pattern. Am J Psychiatr. 2003;160(10):1768–74.CrossRef

83.

Hall J, Whalley HC, McKirdy JW, Romaniuk L, McGonigle D, McIntosh AM, et al. Overactivation of fear systems to neutral faces in schizophrenia. Biol Psychiatry. 2008;64(1):70–3.CrossRef

84.

Carter CS, Krus MK. Dynamic cognitive control and frontal-cingulate interactions. In: Cognitive neuroscience of attention. 2nd ed. NY: Guilford Press; 2012. p. 88–98.

85.

Nyberg L. Cognitive control in the prefrontal cortex: a central or distributed executive? Scand J Psychol. 2018;59(1):62–5. https://doi.org/10.1111/sjop.12409.CrossRefPubMed

86.

Laurenson C, Gorwood P, Orsat M, Lhuillier JP, Le Gall D, Richard-Devantoy S. Cognitive control and schizophrenia: the greatest reliability of the Stroop task. Psychiatry Res. 2015;227(1):10–6.CrossRef

87.

Cadena EJ, White DM, Kraguljac NV, Reid MA, Lahti AC. Evaluation of fronto-striatal networks during cognitive control in unmedicated patients with schizophrenia and the effect of antipsychotic medication. NPJ Schizophr. 2018;4(1):8.CrossRef

88.

Kohler S, Wagner G, Bar KJ. Activation of brainstem and midbrain nuclei during cognitive control in medicated patients with schizophrenia. Hum Brain Mapp. 2019;40(1):202–13.CrossRef

89.

Ragland JD, Ranganath C, Phillips J, Boudewyn MA, Kring AM, Lesh TA, et al. Cognitive control of episodic memory in schizophrenia: differential role of dorsolateral and ventrolateral prefrontal cortex. Front Hum Neurosci. 2015;9:604.CrossRef

90.

Barch D, Culbreth C, Sheffield J. Systems level modeling of cognitive control in psychiatric disorders: a focus on schizophrenia. Comp Psychiatry. 2018:145–73.

91.

Cherek DR, Lane SD, Pietras CJ. Laboratory measures: point subtraction aggression paradigm. Med Psychiat. 2003;22:215–28.

92.

Allen TJ, Dougherty DM, Rhoades HM, Cherek DR. A study of male and female aggressive responding under conditions providing an escape response. Psychol Rec. 1996;46(4):651–64. https://doi.org/10.1007/BF03395190.CrossRef

93.

Anderson CA, Bushman BJ. External validity of “trivial” experiments: The case of laboratory aggression. Rev Gen Psychol. 1997;1(1):19–41. https://doi.org/10.1037/1089-2680.1.1.19.CrossRef

94.

Lawrence C. Measuring individual responses to aggression-triggering events: development of the situational triggers of aggressive responses (STAR) scale. Aggress Behav: Official Journal of the International Society for Research on Aggression. 2006;32(3):241–52. https://doi.org/10.1002/ab.20122.CrossRef

95.

•• Beyer F, Buades-Rotger M, Claes M, Krämer UM. hit or run: exploring aggressive and avoidant reactions to interpersonal provocation using a novel fight-or-escape paradigm (FOE). Front Behav Neurosci. 2017;11:190. https://doi.org/10.3389/fnbeh.2017.00190 Explores the approach–avoidance conflict of aggression. CrossRefPubMedPubMedCentral

96.

• Verona E, Bresin K. Aggression proneness: transdiagnostic processes involving negative valence and cognitive systems. Int J Psychophysiol. 2015;98(2):321–9. https://doi.org/10.1016/j.ijpsycho.2015.03.008 Maps the transdiagonistic dimension of aggression proneness to RDoC and suggests both Negative Valence and Cognitive Systems are involved in aggressive behavior. CrossRefPubMed

Titel: Frustrative Non-reward and Lab-Based Paradigms for Advancing the Study of Aggression in Persons with Psychosis
verfasst von: Jill Del Pozzo
Christina Athineos
Taylor Zar
Lisa N. Cruz
Christopher M. King
Publikationsdatum: 01.06.2019
Verlag: Springer International Publishing
Erschienen in: Current Behavioral Neuroscience Reports / Ausgabe 2/2019
Elektronische ISSN: 2196-2979
DOI: https://doi.org/10.1007/s40473-019-00173-6

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Bipolare Störung
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Eine Mutation in einem einzelnen Gen kann bei Mäusen eine Art Bipolarstörung auslösen. PD Dr. Jan Deussing vom Max-Planck-Institut für Psychiatrie in München sieht in solchen Tiermodellen eine Möglichkeit, den Ursachen der Erkrankung auf den Grund zu gehen.

Suizidassistenz erhöht Suizidzahlen: Aktuelle Ergebnisse der geplanten S3-Leitlinie

DGPPN 2024
Kongressbericht

Erstmals wird in Deutschland eine S3-Leitlinie zum Thema Suizidalität erarbeitet. Ziel ist es, die Versorgung in suizidalen Krisen durch einheitliche Standards zu verbessern. Erste Ergebnisse der bisherigen Leitlinienarbeit wurden auf dem DGPPN-Kongress vorgestellt.

Kaum Vorteile durch intraarterielle Lyse während Thrombektomie

17.01.2025
Ischämischer Schlaganfall
Nachrichten

Nach der Thrombektomie kleinere Fragmente über eine intraarterielle Lyse auflösen – dies könnte die Schlaganfalltherapie verbessern. Zwei aktuelle Studien ergeben für die periprozedurale Lyse jedoch keine großen Vorteile. Die Frage, wie viel sie nützt, bleibt weiter offen.

Nasenstimulation lindert chronische Migräne

16.01.2025
Chronische Migräne
Nachrichten

Wird die Naseninnenseite durch Vibrationen stimuliert, kann dies offenbar die Zahl der Migränetage von Menschen mit chronischer Migräne deutlich senken. Darauf deuten die Resultate einer randomisiert-kontrollierten deutsch-finnischen Untersuchung.

Update Neurologie

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Springer Medizin

Frustrative Non-reward and Lab-Based Paradigms for Advancing the Study of Aggression in Persons with Psychosis

Abstract

Purpose of Review

Recent Findings

Summary

Weitere Artikel der Ausgabe 2/2019

Frontal Alpha Asymmetry in Youth at Clinical High Risk for Psychosis

Remote Monitoring for Understanding Mechanisms and Prediction in Psychiatry

Remediation of Visual Processing Impairments in Schizophrenia: Where We Are and Where We Need to Be

Good Clinical Science Needs Rigorous Methodology, Enhanced Reproducibility, and Also Proper Citations

Galantamine-Memantine Combination as an Antioxidant Treatment for Schizophrenia

Kompaktes Leitlinien-Wissen Neurologie (Link öffnet in neuem Fenster)

Neu im Fachgebiet Neurologie

„Wir wollen die Bedeutung von Gen- und Umwelteinflüssen besser verstehen“

Suizidassistenz erhöht Suizidzahlen: Aktuelle Ergebnisse der geplanten S3-Leitlinie

Kaum Vorteile durch intraarterielle Lyse während Thrombektomie

Nasenstimulation lindert chronische Migräne

Update Neurologie

Springer Medizin

Abstract

Purpose of Review

Recent Findings

Summary

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