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Erschienen in: Documenta Ophthalmologica 1/2014

01.02.2014 | Clinical Case Report

Functional and high resolution retinal imaging assessment in a case of ocular siderosis

verfasst von: Céline Faure, Kiyoko Gocho, Yannick Le Mer, José Alain Sahel, Michel Paques, Isabelle Audo

Erschienen in: Documenta Ophthalmologica | Ausgabe 1/2014

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Abstract

Purpose

To report new findings in a case of ocular siderosis explored by high resolution angiography and adaptive optics (AO).

Methods

We report data on a 40-year-old man with an intraocular foreign body (IOFB) embedded in the sclera after hammering.

Results

Nine months after this accident, the patient presented with full-field electroretinogram (FF-ERG) abnormalities. Subsequent IOFB extraction was performed. One month after the surgery, high resolution angiography showed for the first time small iron particles all over the inner retinal surface. Spreading of these deposits was followed by inflammatory prepapillary new vessels and venous retinal vasculatis, which spontaneously resolved within a few months. ERG responses became slightly electronegative at this time. Clearance of the iron particles was followed over a year with AO and ERG recording. AO revealed an arterial tropism with a decrease in the amount of particles overtime, which may be consistent with macrophagic activity.

Conclusion

High resolution angiography and AO are new tools, combined with electrophysiology, to better understand ocular siderosis pathophysiology.
Literatur
1.
Zurück zum Zitat Declercq SS, Meredith PC, Rosenthal AR (1977) Experimental siderosis in the rabbit: correlation between electroretinography and histopathology. Arch Ophthalmol 95(6):1051–1058PubMedCrossRef Declercq SS, Meredith PC, Rosenthal AR (1977) Experimental siderosis in the rabbit: correlation between electroretinography and histopathology. Arch Ophthalmol 95(6):1051–1058PubMedCrossRef
2.
Zurück zum Zitat O’Duffy D, Salmon JF (1999) Siderosis bulbi resulting from an intralenticular foreign body. Am J Ophthalmol 127(2):218–219PubMedCrossRef O’Duffy D, Salmon JF (1999) Siderosis bulbi resulting from an intralenticular foreign body. Am J Ophthalmol 127(2):218–219PubMedCrossRef
3.
Zurück zum Zitat Janssens D, Libert J (1999) Anatomic-clinical study of two cases of ocular siderosis. Bull Soc Belge Ophtalmol 272:115–119PubMed Janssens D, Libert J (1999) Anatomic-clinical study of two cases of ocular siderosis. Bull Soc Belge Ophtalmol 272:115–119PubMed
4.
Zurück zum Zitat Sangermani C, Mora P, Mancini C, Vecchi M, Gandolfi SA (2010) Ultrasound biomicroscopy in two cases of ocular siderosis with secondary glaucoma. Acta Ophthalmol 88(1):e1–e2PubMedCrossRef Sangermani C, Mora P, Mancini C, Vecchi M, Gandolfi SA (2010) Ultrasound biomicroscopy in two cases of ocular siderosis with secondary glaucoma. Acta Ophthalmol 88(1):e1–e2PubMedCrossRef
5.
Zurück zum Zitat Shaikh S, Blumenkranz MS (2001) Fluorescein angiographic findings in ocular siderosis. Am J Ophthalmol 131(1):136–138PubMedCrossRef Shaikh S, Blumenkranz MS (2001) Fluorescein angiographic findings in ocular siderosis. Am J Ophthalmol 131(1):136–138PubMedCrossRef
6.
Zurück zum Zitat Cleary G, Sheth HG, Laidlaw AH (2007) Delayed transient macular ischaemia due to ocular siderosis. Eye (Lond) 21(8):1132–1133 Epub 2007 Jun 15CrossRef Cleary G, Sheth HG, Laidlaw AH (2007) Delayed transient macular ischaemia due to ocular siderosis. Eye (Lond) 21(8):1132–1133 Epub 2007 Jun 15CrossRef
7.
Zurück zum Zitat Sieving PA, Fishman GA, Alexander KR, Goldberg MF (1983) Early receptor potential measurements in human ocular siderosis. Arch Ophthalmol 101(11):1716–1720PubMedCrossRef Sieving PA, Fishman GA, Alexander KR, Goldberg MF (1983) Early receptor potential measurements in human ocular siderosis. Arch Ophthalmol 101(11):1716–1720PubMedCrossRef
8.
Zurück zum Zitat Schechner R, Miller B, Merksamer E, Perlman I (1990) A long term follow up of ocular siderosis: quantitative assessment of the electroretinogram. Doc Ophthalmol 76(3):231–240PubMedCrossRef Schechner R, Miller B, Merksamer E, Perlman I (1990) A long term follow up of ocular siderosis: quantitative assessment of the electroretinogram. Doc Ophthalmol 76(3):231–240PubMedCrossRef
9.
Zurück zum Zitat Marmor MF, Fulton AB, Holder GE, Miyake Y, Brigell M, Bach M (2009) International Society for Clinical Electrophysiology of Vision. ISCEV Standard for full-field clinical electroretinography (2008 update). Doc Ophthalmol 118(1):69–77PubMedCrossRef Marmor MF, Fulton AB, Holder GE, Miyake Y, Brigell M, Bach M (2009) International Society for Clinical Electrophysiology of Vision. ISCEV Standard for full-field clinical electroretinography (2008 update). Doc Ophthalmol 118(1):69–77PubMedCrossRef
10.
Zurück zum Zitat Tanabe J, Shirao Y, Oda N, Kawasaki K (1992) Evaluation of retinal integrity in eyes with retained intraocular metallic foreign body by ERG and EOG. Doc Ophthalmol 79(1):71–78PubMedCrossRef Tanabe J, Shirao Y, Oda N, Kawasaki K (1992) Evaluation of retinal integrity in eyes with retained intraocular metallic foreign body by ERG and EOG. Doc Ophthalmol 79(1):71–78PubMedCrossRef
11.
Zurück zum Zitat Appel I, Barishak YR (1978) Histopathological changes in siderosis bulbi. Ophthalmologica 176(4):205–210PubMedCrossRef Appel I, Barishak YR (1978) Histopathological changes in siderosis bulbi. Ophthalmologica 176(4):205–210PubMedCrossRef
12.
Zurück zum Zitat Tawara A (1986) Transformation and cytotoxicity of iron in siderosis bulbi. Invest Ophthalmol Vis Sci 27(2):226–236PubMed Tawara A (1986) Transformation and cytotoxicity of iron in siderosis bulbi. Invest Ophthalmol Vis Sci 27(2):226–236PubMed
13.
Zurück zum Zitat Weiss MJ, Hofeldt AJ, Behrens M, Fisher K (1997) Ocular siderosis. Diagnosis and management. Retina 17(2):105–108PubMedCrossRef Weiss MJ, Hofeldt AJ, Behrens M, Fisher K (1997) Ocular siderosis. Diagnosis and management. Retina 17(2):105–108PubMedCrossRef
Metadaten
Titel
Functional and high resolution retinal imaging assessment in a case of ocular siderosis
verfasst von
Céline Faure
Kiyoko Gocho
Yannick Le Mer
José Alain Sahel
Michel Paques
Isabelle Audo
Publikationsdatum
01.02.2014
Verlag
Springer Berlin Heidelberg
Erschienen in
Documenta Ophthalmologica / Ausgabe 1/2014
Print ISSN: 0012-4486
Elektronische ISSN: 1573-2622
DOI
https://doi.org/10.1007/s10633-013-9421-y

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