Background
Methods
Aura (Mean ± SD) | No Aura (Mean ± SD) | HC (Mean ± SD) | |
---|---|---|---|
Age | 41.28 ± 13.44 | 40.75 ± 11.82 | 41.75 ± 12.82 |
Years of education | 15.8 ± 3.2 | 16.7 ± 4.2 | 16.2 ± 4.1 |
Disease duration | 10.9 ± 3.7 | 12.3 ± 5.8 | |
Attack frequency/month (n) | 5.05 ± 2.31 | 6.07 ± 2.81 | |
Single-Attack duration (hours) | 3.58 ± 2.27 | 4.21 ± 2.99 | |
Days to next migraine attack after examination |
Resting state analysis
Results
Demographic characteristics
Test | Aura | No Aura | Controls groups | Cut-off |
---|---|---|---|---|
Attention | ||||
Attentive Matrix | 44.60 ± 4.80 | 45.51 ± 6.91 | 43.35 ± 7.87 | 30 |
Language | ||||
Fluency Phonemic | 32.08 ± 11.72 | 35.35 ± 10.9 | 30.85 ± 6.63 | 17 |
Fluency Semantic | 36.25 ± 6.64 | 36.28 ± 5.86 | 37.42 ± 5.74 | 25 |
Memory | ||||
RAVLT (Immediate recall) | 40.86 ± 25.01 | 36.28 ± 5.86 | 38.17 ± 4.59 | 28.53 |
RAVLT (Delayed recall) | 8.2 ± 2.45 | 9.23 ± 3.10 | 6.85 ± 1.65 | 4.69 |
Executive Functions | ||||
Trial Making Test-A | 42.62 ± 25.01 | 48.73 ± 55.20 | 55.28 ± 15.52 | 93 |
Trial Making Test-B | 123.35 ± 56.28 | 155.14 ± 70.16 | 126.64 ± 30.49 | 282 |
Resting state
MA vs MO
Brain Structure | Peak voxel coordinates (MNI) | Peak T-score | ||
---|---|---|---|---|
x | y | z | ||
Right Central Opercular Cortex | 48 | -6 | 6 | 3.89 |
Right Insular cortex | 42 | −9 | 6 | 4.97 |
Right first and second Heschl’s Gyrus | 45 | −12 | 6 | 4.12 |
Left Central Opercular Cortex | −45 | −9 | 6 | 3.17 |
Left first and second Heschl’s Gyrus | −51 | −15 | 6 | 3.75 |
Left Superior Temporal gyrus | −69 | −27 | 6 | 3.41 |
Right Lingual gyrus | 18 | −66 | −12 | 4.61 |
Right Occipital fusiform gyrus | 18 | −75 | −12 | 5.48 |
Left occipital pole | −12 | −93 | −12 | 6.60 |
Left Lingual gyrus | −12 | −84 | −12 | 6.82 |
MA vs HC
Brain Structure | Peak voxel coordinates (MNI) | Peak T-score | ||
---|---|---|---|---|
x | y | z | ||
Right Heschi’s | 54 | -15 | 6 | 4.20 |
Right Planum temporale | 54 | −21 | 6 | 3.97 |
Left Heschi’s gyrus | −54 | −15 | 6 | 3.80 |
Left Planum temporale | −57 | −21 | 6 | 3.51 |
Left Superior temporal gyrus | −57 | −33 | 6 | 3.75 |
MO vs HC
Brain Structure | Peak voxel coordinates (MNI) | Peak T-score | ||
---|---|---|---|---|
x | y | z | ||
Right Lingual gyrus | 18 | −54 | 0 | 3.54 |
Right Occipital fusiform gyrus | 21 | −75 | 0 | 3.21 |
Right Occipital pole | 9 | −93 | 0 | 4.85 |
Right Cingulate gyrus | 18 | −45 | 0 | 2.8 |
Left Lingual gyrus | −18 | −54 | 0 | 4.0 |
Left Occipital fusiform gyrus | −21 | −75 | 0 | 3.1 |
Left Occipital pole | −9 | −93 | 0 | 4.57 |
Left Cingulate gyrus | −12 | −45 | 0 | 3.5 |