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Erschienen in: Updates in Surgery 4/2016

29.01.2016 | Original Article

Functional outcomes of transmetatarsal amputation in the diabetic foot: timing of revascularization, wound healing and ambulatory status

verfasst von: T. Mandolfino, A. Canciglia, M. Salibra, D. Ricciardello, G. Cuticone

Erschienen in: Updates in Surgery | Ausgabe 4/2016

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Abstract

Transmetatarsal amputation (TMA) is an effective surgical approach to treat forefoot infection and gangrene in diabetic patients. However, a high rate of complications and failure to heal require reamputation in a large number of cases. We analysed the outcomes of TMA to define the role of revascularization, wound healing and ambulatory status. From January 2008 to January 2013, 218 diabetic patients with foot infection and gangrene, submitted to TMA associated to revascularization were followed until healing, amputation or death. Revascularization was done in 202 (92 %) cases. In 16 (7 %) no revascularization was required. The TMA was closed in 135 (62 %) and left open in 83 (38 %) cases. The reamputation rate was 34 % and major amputation 12.6 % at 1-year follow-up. Patient following ranged 2–30 months with a mean of 15 months. The functional outcomes, living at home and ambulation outdoors, were 60 and 36 % at hospital discharge after TMA, 81 and 77 % at 1-year follow-up. TMA associated to revascularization can provide an effective limb salvage and functional results in diabetic patients with forefoot tissue loss and infection.
Literatur
1.
Zurück zum Zitat Peterson CM, Peterson KP, Jovanovic I (1998) Influence of diabetes on vascular disease and its complications. In: Moore WS (ed) Vascular surgery: a comprehensive review, 5th edn. WB Saunders, Philadelphia, pp 146–167 Peterson CM, Peterson KP, Jovanovic I (1998) Influence of diabetes on vascular disease and its complications. In: Moore WS (ed) Vascular surgery: a comprehensive review, 5th edn. WB Saunders, Philadelphia, pp 146–167
2.
Zurück zum Zitat Narayan KM, Boyle JP, Geiss LS, Saaddine JB, Thompson TJ (2006) Impact of recent increase in incidence on future diabetes burden: U.S. 2005–2050. Diabetes Care 29:2114–2116CrossRefPubMed Narayan KM, Boyle JP, Geiss LS, Saaddine JB, Thompson TJ (2006) Impact of recent increase in incidence on future diabetes burden: U.S. 2005–2050. Diabetes Care 29:2114–2116CrossRefPubMed
3.
Zurück zum Zitat Taylor LM, Porter JM (1987) The clinical course of diabetics who require emergent foot surgery because of infection or ischemia. J Vasc Surg 6:454–459CrossRefPubMed Taylor LM, Porter JM (1987) The clinical course of diabetics who require emergent foot surgery because of infection or ischemia. J Vasc Surg 6:454–459CrossRefPubMed
4.
Zurück zum Zitat Thomas SRYW, Perkins JMT, Magee TR, Galland RB (2001) Transmetatarsal amputation: an 8-year experience. Ann R Coll Surg Engl 83:164–166PubMedPubMedCentral Thomas SRYW, Perkins JMT, Magee TR, Galland RB (2001) Transmetatarsal amputation: an 8-year experience. Ann R Coll Surg Engl 83:164–166PubMedPubMedCentral
5.
Zurück zum Zitat Miller N, Dardik H, Wolodiger F, Pecoraro J, Kahn M, Ibrahim IM et al (1991) Transmetatarsal amputation: the role of adjunctive revascularization. J Vasc Surg 13:705–711CrossRefPubMed Miller N, Dardik H, Wolodiger F, Pecoraro J, Kahn M, Ibrahim IM et al (1991) Transmetatarsal amputation: the role of adjunctive revascularization. J Vasc Surg 13:705–711CrossRefPubMed
6.
Zurück zum Zitat Sheahan MG, Hamdan AD, Veraldi JR, Mc Arthur CS et al (2005) Lower extremity minor amputations: the roles of diabetes mellitus and timing of revascularization. J Vasc Surg 42:476–480CrossRefPubMed Sheahan MG, Hamdan AD, Veraldi JR, Mc Arthur CS et al (2005) Lower extremity minor amputations: the roles of diabetes mellitus and timing of revascularization. J Vasc Surg 42:476–480CrossRefPubMed
7.
Zurück zum Zitat Frykberg RG (2003) An evidence based approach to diabetic foot infections. Am J Surg 186(5A):44S–55SCrossRefPubMed Frykberg RG (2003) An evidence based approach to diabetic foot infections. Am J Surg 186(5A):44S–55SCrossRefPubMed
8.
Zurück zum Zitat Eneroth M, Apelqvist J, Stenstrom A (1997) Clinical characteristics and out-come in 223 diabetic patients with deep foot infections. Foot Ankle Int 18:716–722CrossRefPubMed Eneroth M, Apelqvist J, Stenstrom A (1997) Clinical characteristics and out-come in 223 diabetic patients with deep foot infections. Foot Ankle Int 18:716–722CrossRefPubMed
9.
Zurück zum Zitat Pollard J, Hamilton GA, Rush SM, Ford LA (2006) Mortality and morbidity after transmetatarsal amputation: retrospective review of 101 cases. J Foot Ankle Surg 45(2):91–97CrossRefPubMed Pollard J, Hamilton GA, Rush SM, Ford LA (2006) Mortality and morbidity after transmetatarsal amputation: retrospective review of 101 cases. J Foot Ankle Surg 45(2):91–97CrossRefPubMed
10.
Zurück zum Zitat Izumi Y, Lee S, Satterfield K, Harkless L (2006) Risk of reamputation in diabetic patients stratified by limb and level of amputation. Diabetes Care 29:566–570CrossRefPubMed Izumi Y, Lee S, Satterfield K, Harkless L (2006) Risk of reamputation in diabetic patients stratified by limb and level of amputation. Diabetes Care 29:566–570CrossRefPubMed
11.
Zurück zum Zitat Snyder DC, Salameh JR, Clericuzio CP (2006) Retrospective review of forefoot amputations at a Veterans Affairs hospital and evaluation of post-amputation follow-up. Am J Surg 192:e51–e54CrossRefPubMed Snyder DC, Salameh JR, Clericuzio CP (2006) Retrospective review of forefoot amputations at a Veterans Affairs hospital and evaluation of post-amputation follow-up. Am J Surg 192:e51–e54CrossRefPubMed
12.
Zurück zum Zitat Nerone VS, Springer KD, Woodruff DM, Atway SA (2013) Reamputation after minor foot amputation in diabetic patients: risk factors leading to limb loss. J Foot Ankle Surg 52:184–187CrossRefPubMedPubMedCentral Nerone VS, Springer KD, Woodruff DM, Atway SA (2013) Reamputation after minor foot amputation in diabetic patients: risk factors leading to limb loss. J Foot Ankle Surg 52:184–187CrossRefPubMedPubMedCentral
13.
Zurück zum Zitat Flu HC, Lardenoye JWHP, Veen EJ, Van Berge Henegouwen DP, Hamming JF (2010) Functional status as a prognostic factor for primary revascularization for critical limb ischemia. J Vasc Surg 51:360–371CrossRefPubMed Flu HC, Lardenoye JWHP, Veen EJ, Van Berge Henegouwen DP, Hamming JF (2010) Functional status as a prognostic factor for primary revascularization for critical limb ischemia. J Vasc Surg 51:360–371CrossRefPubMed
14.
Zurück zum Zitat Nehler MR, Whitehill TA, Bowers SP et al (1999) Intermediate-term outcome of primary digit amputations in patients with diabetes mellitus who have forefoot sepsis requiring hospitalisation and presumed adequate circulatory status. J Vasc Surg 30:509–517CrossRefPubMed Nehler MR, Whitehill TA, Bowers SP et al (1999) Intermediate-term outcome of primary digit amputations in patients with diabetes mellitus who have forefoot sepsis requiring hospitalisation and presumed adequate circulatory status. J Vasc Surg 30:509–517CrossRefPubMed
15.
Zurück zum Zitat Taylor SM, Kalbaugh CA, Blackhurst DW et al (2005) Preoperative clinical factors predict postoperative functional outcomes after major lower limb amputation: an analysis of 553 consecutive patients. J Vasc Surg 42:227–234CrossRefPubMed Taylor SM, Kalbaugh CA, Blackhurst DW et al (2005) Preoperative clinical factors predict postoperative functional outcomes after major lower limb amputation: an analysis of 553 consecutive patients. J Vasc Surg 42:227–234CrossRefPubMed
16.
Zurück zum Zitat Frykberg RG, Wittmayer B, Zgonis T (2007) Surgical management of diabetic foot infections and osteomyelitis. Clin Podiatr Med Surg 24:469–482CrossRefPubMed Frykberg RG, Wittmayer B, Zgonis T (2007) Surgical management of diabetic foot infections and osteomyelitis. Clin Podiatr Med Surg 24:469–482CrossRefPubMed
17.
Zurück zum Zitat Aragon Sanchez FJ, Cabrera Galvan JJ, Quintana Marrero Y, Hernandez Herrero MJ et al (2008) Outcomes of surgical treatment of diabetic foot osteomyelitis: a series of 185 patients with histopathological confirmation of bone involvement. Diabetologia 51(11):1962–1970CrossRefPubMed Aragon Sanchez FJ, Cabrera Galvan JJ, Quintana Marrero Y, Hernandez Herrero MJ et al (2008) Outcomes of surgical treatment of diabetic foot osteomyelitis: a series of 185 patients with histopathological confirmation of bone involvement. Diabetologia 51(11):1962–1970CrossRefPubMed
18.
Zurück zum Zitat Henke PK, Blackburn SA, Wainess RW et al (2005) Osteomyelitis of the foot and toe in adults is a surgical disease: conservative management worsen lower extremity salvage. Ann Surg 214:885–892CrossRef Henke PK, Blackburn SA, Wainess RW et al (2005) Osteomyelitis of the foot and toe in adults is a surgical disease: conservative management worsen lower extremity salvage. Ann Surg 214:885–892CrossRef
Metadaten
Titel
Functional outcomes of transmetatarsal amputation in the diabetic foot: timing of revascularization, wound healing and ambulatory status
verfasst von
T. Mandolfino
A. Canciglia
M. Salibra
D. Ricciardello
G. Cuticone
Publikationsdatum
29.01.2016
Verlag
Springer Milan
Erschienen in
Updates in Surgery / Ausgabe 4/2016
Print ISSN: 2038-131X
Elektronische ISSN: 2038-3312
DOI
https://doi.org/10.1007/s13304-015-0341-0

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