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Pediatric Radiology

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01.04.2019 | Minisymposium: Quality and safety

Gadolinium-based contrast agents — review of recent literature on magnetic resonance imaging signal intensity changes and tissue deposits, with emphasis on pediatric patients

verfasst von: Einat Blumfield, David W. Swenson, Ramesh S. Iyer, A. Luana Stanescu

Erschienen in: Pediatric Radiology | Ausgabe 4/2019

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Abstract

Gadolinium has been used as a base for contrast agents in MRI for the last three decades. Numerous studies over the last 4 years have reported increased signal intensity in deep brain nuclei in non-contrast MRI images following gadolinium-based contrast agent (GBCA) administration. Pathology studies performed on adults and children, and rodent necropsy studies have also shown gadolinium deposition in brain and other tissues after GBCA administration. The purpose of this review was to summarize and discuss the knowledge gained from these reports and the relevance for imaging pediatric patients.

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Titel: Gadolinium-based contrast agents — review of recent literature on magnetic resonance imaging signal intensity changes and tissue deposits, with emphasis on pediatric patients
verfasst von: Einat Blumfield
David W. Swenson
Ramesh S. Iyer
A. Luana Stanescu
Publikationsdatum: 01.04.2019
Verlag: Springer Berlin Heidelberg
Erschienen in: Pediatric Radiology / Ausgabe 4/2019
Print ISSN: 0301-0449
Elektronische ISSN: 1432-1998
DOI: https://doi.org/10.1007/s00247-018-4304-8

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Gadolinium-based contrast agents — review of recent literature on magnetic resonance imaging signal intensity changes and tissue deposits, with emphasis on pediatric patients

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