10.07.2023 | Original reports
Genetic portrait of 23 Y-STR loci in the Brahmin population of Haryana, India
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In India, there is a lack of Y‑STR haplotype data of different castes/groups. In this direction, we have conducted the present study for the first time to generate the Y‑STR haplotype data of Haryana Brahmin population. Forensic application and genetic diversity of the Brahmin population of Haryana (India) were studied using 23 Y-STR markers in 104 male individuals. Several forensic parameters such as haplotype diversity (HD), allelic and haplotype frequency, discrimination power (PD), polymorphism information content (PIC) and random match probability (PM) were assessed for this population. Pairwise Rst values were also evaluated by analyzing AMOVA and envisioned through multidimensional scaling (MDS) plot. The average discrimination capacity (DC), HD and gene diversity (GD) values of the panel were found to be 0.9696, 0.999 and 0.654, respectively. Overall, 99 complete haplotype profiles were generated in 104 individuals of whom 93 were unique and three haplotypes were found twice. DYS576 and DYS481 markers showed the presence of micro-variant alleles. Our results conclude that 23 Y-STRs loci in the Brahmins of Haryana are forensically potent and might contribute to our understanding of the genealogical relationship between Brahmin and other Indian populations. In addition, generated genetic data of the Brahmin population of Haryana will enrich the population data bank.