Skip to main content
Erschienen in: Clinical Research in Cardiology 2/2018

16.05.2018 | Review

German contribution to development and innovations in the management of acute myocardial infarction and cardiogenic shock

verfasst von: Hans-Josef Feistritzer, Steffen Desch, Suzanne de Waha, Alexander Jobs, Uwe Zeymer, Holger Thiele

Erschienen in: Clinical Research in Cardiology | Sonderheft 2/2018

Einloggen, um Zugang zu erhalten

Abstract

Treatment of acute coronary syndromes has evolved over time leading to a significantly reduced mortality. Multiple major trials have been performed in Germany leading to new treatment strategies in acute coronary syndromes including cardiogenic shock. This review article will summarize major trials and their impact on guideline recommendations in acute myocardial infarction highlighting reperfusion strategies, antiplatelet regimens, prognosis assessment and also mechanical circulatory support in stable infarction patients and in cardiogenic shock.
Literatur
1.
Zurück zum Zitat de Vreede JJ, Gorgels AP, Verstraaten GM, Vermeer F, Dassen WR, Wellens HJ (1991) Did prognosis after acute myocardial infarction change during the past 30 years? A meta-analysis. J Am Coll Cardiol 18(3):698–706CrossRefPubMed de Vreede JJ, Gorgels AP, Verstraaten GM, Vermeer F, Dassen WR, Wellens HJ (1991) Did prognosis after acute myocardial infarction change during the past 30 years? A meta-analysis. J Am Coll Cardiol 18(3):698–706CrossRefPubMed
2.
Zurück zum Zitat Kristensen SD, Laut KG, Fajadet J, Kaifoszova Z, Kala P, Di Mario C et al (2014) Reperfusion therapy for ST elevation acute myocardial infarction 2010/2011: current status in 37 ESC countries. Eur Heart J 35(29):1957–1970CrossRefPubMed Kristensen SD, Laut KG, Fajadet J, Kaifoszova Z, Kala P, Di Mario C et al (2014) Reperfusion therapy for ST elevation acute myocardial infarction 2010/2011: current status in 37 ESC countries. Eur Heart J 35(29):1957–1970CrossRefPubMed
3.
Zurück zum Zitat Thiele H, Akin I, Sandri M, Fuernau G, de Waha S, Meyer-Saraei R et al (2017) PCI strategies in patients with acute myocardial infarction and cardiogenic shock. N Engl J Med 377(25):2419–2432CrossRefPubMed Thiele H, Akin I, Sandri M, Fuernau G, de Waha S, Meyer-Saraei R et al (2017) PCI strategies in patients with acute myocardial infarction and cardiogenic shock. N Engl J Med 377(25):2419–2432CrossRefPubMed
4.
Zurück zum Zitat Thiele H, Zeymer U, Neumann FJ, Ferenc M, Olbrich HG, Hausleiter J et al (2012) Intraaortic balloon support for myocardial infarction with cardiogenic shock. N Engl J Med 367(14):1287–1296CrossRefPubMed Thiele H, Zeymer U, Neumann FJ, Ferenc M, Olbrich HG, Hausleiter J et al (2012) Intraaortic balloon support for myocardial infarction with cardiogenic shock. N Engl J Med 367(14):1287–1296CrossRefPubMed
5.
Zurück zum Zitat Thiele H, Ohman EM, Desch S, Eitel I, de Waha S (2015) Management of cardiogenic shock. Eur Heart J 36(20):1223–1230CrossRefPubMed Thiele H, Ohman EM, Desch S, Eitel I, de Waha S (2015) Management of cardiogenic shock. Eur Heart J 36(20):1223–1230CrossRefPubMed
6.
Zurück zum Zitat Niccoli G, Burzotta F, Galiuto L, Crea F (2009) Myocardial no-reflow in humans. J Am Coll Cardiol 54(4):281–292CrossRefPubMed Niccoli G, Burzotta F, Galiuto L, Crea F (2009) Myocardial no-reflow in humans. J Am Coll Cardiol 54(4):281–292CrossRefPubMed
7.
Zurück zum Zitat Zeymer U, Arntz H-R, Mark B, Fichtlscherer S, Werner G, Schöller R et al (2012) Efficacy and safety of a high loading dose of clopidogrel administered prehospitally to improve primary percutaneous coronary intervention in acute myocardial infarction: the randomized CIPAMI trial. Clin Res Cardiol 101(4):305–312CrossRefPubMed Zeymer U, Arntz H-R, Mark B, Fichtlscherer S, Werner G, Schöller R et al (2012) Efficacy and safety of a high loading dose of clopidogrel administered prehospitally to improve primary percutaneous coronary intervention in acute myocardial infarction: the randomized CIPAMI trial. Clin Res Cardiol 101(4):305–312CrossRefPubMed
8.
Zurück zum Zitat Montalescot G, van ’t Hof AW, Lapostolle F, Silvain J, Lassen JF, Bolognese L et al (2014) Prehospital ticagrelor in ST-segment elevation myocardial infarction. N Engl J Med 371(11):1016–1027CrossRefPubMed Montalescot G, van ’t Hof AW, Lapostolle F, Silvain J, Lassen JF, Bolognese L et al (2014) Prehospital ticagrelor in ST-segment elevation myocardial infarction. N Engl J Med 371(11):1016–1027CrossRefPubMed
9.
Zurück zum Zitat Zeymer U, Hohlfeld T, vom Dahl J, Erbel R, Münzel T, Zahn R et al (2017) Prospective, randomised trial of the time dependent antiplatelet effects of 500 mg and 250 mg acetylsalicylic acid i.v. and 300 mg p.o. in ACS (ACUTE). Thromb Haemostasis 117(3):625 – 35CrossRef Zeymer U, Hohlfeld T, vom Dahl J, Erbel R, Münzel T, Zahn R et al (2017) Prospective, randomised trial of the time dependent antiplatelet effects of 500 mg and 250 mg acetylsalicylic acid i.v. and 300 mg p.o. in ACS (ACUTE). Thromb Haemostasis 117(3):625 – 35CrossRef
10.
Zurück zum Zitat Ibanez B, James S, Agewall S, Antunes MJ, Bucciarelli-Ducci C, Bueno H et al (2018) 2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation: the task force for the management of acute myocardial infarction in patients presenting with ST-segment elevation of the European Society of Cardiology (ESC). Eur Heart J 39(2):119 – 77CrossRefPubMed Ibanez B, James S, Agewall S, Antunes MJ, Bucciarelli-Ducci C, Bueno H et al (2018) 2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation: the task force for the management of acute myocardial infarction in patients presenting with ST-segment elevation of the European Society of Cardiology (ESC). Eur Heart J 39(2):119 – 77CrossRefPubMed
11.
Zurück zum Zitat Zeymer U, Margenet A, Haude M, Bode C, Lablanche J-M, Heuer H et al (2010) Randomized comparison of eptifibatide versus abciximab in primary percutaneous coronary intervention in patients with acute ST-segment elevation myocardial infarction: results of the EVA-AMI trial. J Am Coll Cardiol 56(6):463–469CrossRefPubMed Zeymer U, Margenet A, Haude M, Bode C, Lablanche J-M, Heuer H et al (2010) Randomized comparison of eptifibatide versus abciximab in primary percutaneous coronary intervention in patients with acute ST-segment elevation myocardial infarction: results of the EVA-AMI trial. J Am Coll Cardiol 56(6):463–469CrossRefPubMed
12.
Zurück zum Zitat Thiele H, Wohrle J, Hambrecht R, Rittger H, Birkemeyer R, Lauer B et al (2012) Intracoronary versus intravenous bolus abciximab during primary percutaneous coronary intervention in patients with acute ST-elevation myocardial infarction: a randomised trial. Lancet 379(9819):923–931CrossRefPubMed Thiele H, Wohrle J, Hambrecht R, Rittger H, Birkemeyer R, Lauer B et al (2012) Intracoronary versus intravenous bolus abciximab during primary percutaneous coronary intervention in patients with acute ST-elevation myocardial infarction: a randomised trial. Lancet 379(9819):923–931CrossRefPubMed
13.
Zurück zum Zitat Eitel I, Wohrle J, Suenkel H, Meissner J, Kerber S, Lauer B et al (2013) Intracoronary compared with intravenous bolus abciximab application during primary percutaneous coronary intervention in ST-segment elevation myocardial infarction: cardiac magnetic resonance substudy of the AIDA STEMI trial. J Am Coll Cardiol 61(13):1447–1454CrossRefPubMed Eitel I, Wohrle J, Suenkel H, Meissner J, Kerber S, Lauer B et al (2013) Intracoronary compared with intravenous bolus abciximab application during primary percutaneous coronary intervention in ST-segment elevation myocardial infarction: cardiac magnetic resonance substudy of the AIDA STEMI trial. J Am Coll Cardiol 61(13):1447–1454CrossRefPubMed
14.
Zurück zum Zitat Kastrati A, Neumann FJ, Schulz S, Massberg S, Byrne RA, Ferenc M et al (2011) Abciximab and heparin versus bivalirudin for non-ST-elevation myocardial infarction. N Engl J Med 365(21):1980–1989CrossRefPubMed Kastrati A, Neumann FJ, Schulz S, Massberg S, Byrne RA, Ferenc M et al (2011) Abciximab and heparin versus bivalirudin for non-ST-elevation myocardial infarction. N Engl J Med 365(21):1980–1989CrossRefPubMed
15.
Zurück zum Zitat Grines CL, Browne KF, Marco J, Rothbaum D, Stone GW, O’Keefe J et al (1993) A comparison of immediate angioplasty with thrombolytic therapy for acute myocardial infarction. The Primary Angioplasty in Myocardial Infarction Study Group. N Engl J Med 328(10):673–679CrossRefPubMed Grines CL, Browne KF, Marco J, Rothbaum D, Stone GW, O’Keefe J et al (1993) A comparison of immediate angioplasty with thrombolytic therapy for acute myocardial infarction. The Primary Angioplasty in Myocardial Infarction Study Group. N Engl J Med 328(10):673–679CrossRefPubMed
16.
Zurück zum Zitat Zijlstra F, Hoorntje JC, de Boer MJ, Reiffers S, Miedema K, Ottervanger JP et al (1999) Long-term benefit of primary angioplasty as compared with thrombolytic therapy for acute myocardial infarction. N Engl J Med 341(19):1413–1419CrossRefPubMed Zijlstra F, Hoorntje JC, de Boer MJ, Reiffers S, Miedema K, Ottervanger JP et al (1999) Long-term benefit of primary angioplasty as compared with thrombolytic therapy for acute myocardial infarction. N Engl J Med 341(19):1413–1419CrossRefPubMed
17.
Zurück zum Zitat Schomig A, Kastrati A, Dirschinger J, Mehilli J, Schricke U, Pache J et al (2000) Coronary stenting plus platelet glycoprotein IIb/IIIa blockade compared with tissue plasminogen activator in acute myocardial infarction. Stent versus Thrombolysis for Occluded Coronary Arteries in Patients with Acute Myocardial Infarction Study Investigators. N Engl J Med 343(6):385–391CrossRefPubMed Schomig A, Kastrati A, Dirschinger J, Mehilli J, Schricke U, Pache J et al (2000) Coronary stenting plus platelet glycoprotein IIb/IIIa blockade compared with tissue plasminogen activator in acute myocardial infarction. Stent versus Thrombolysis for Occluded Coronary Arteries in Patients with Acute Myocardial Infarction Study Investigators. N Engl J Med 343(6):385–391CrossRefPubMed
18.
Zurück zum Zitat Kastrati A, Mehilli J, Dirschinger J, Schricke U, Neverve J, Pache J et al (2002) Myocardial salvage after coronary stenting plus abciximab versus fibrinolysis plus abciximab in patients with acute myocardial infarction: a randomised trial. Lancet 359(9310):920–925CrossRefPubMed Kastrati A, Mehilli J, Dirschinger J, Schricke U, Neverve J, Pache J et al (2002) Myocardial salvage after coronary stenting plus abciximab versus fibrinolysis plus abciximab in patients with acute myocardial infarction: a randomised trial. Lancet 359(9310):920–925CrossRefPubMed
19.
Zurück zum Zitat Mehta SR, Granger CB, Boden WE, Steg PG, Bassand JP, Faxon DP et al (2009) Early versus delayed invasive intervention in acute coronary syndromes. N Engl J Med 360(21):2165–2175CrossRefPubMed Mehta SR, Granger CB, Boden WE, Steg PG, Bassand JP, Faxon DP et al (2009) Early versus delayed invasive intervention in acute coronary syndromes. N Engl J Med 360(21):2165–2175CrossRefPubMed
20.
Zurück zum Zitat Thiele H, Rach J, Klein N, Pfeiffer D, Hartmann A, Hambrecht R et al (2012) Optimal timing of invasive angiography in stable non-ST-elevation myocardial infarction: the Leipzig Immediate versus early and late PercutaneouS coronary Intervention triAl in NSTEMI (LIPSIA-NSTEMI Trial). Eur Heart J 33(16):2035–2043CrossRefPubMed Thiele H, Rach J, Klein N, Pfeiffer D, Hartmann A, Hambrecht R et al (2012) Optimal timing of invasive angiography in stable non-ST-elevation myocardial infarction: the Leipzig Immediate versus early and late PercutaneouS coronary Intervention triAl in NSTEMI (LIPSIA-NSTEMI Trial). Eur Heart J 33(16):2035–2043CrossRefPubMed
21.
Zurück zum Zitat Jobs A, Mehta SR, Montalescot G, Vicaut E, van’t Hof AW, Badings EA et al (2017) Optimal timing of invasive strategy in patients with non-ST-elevation acute coronary syndrome: a collaborative meta-analysis of randomised trials. Lancet 390:737–746CrossRefPubMed Jobs A, Mehta SR, Montalescot G, Vicaut E, van’t Hof AW, Badings EA et al (2017) Optimal timing of invasive strategy in patients with non-ST-elevation acute coronary syndrome: a collaborative meta-analysis of randomised trials. Lancet 390:737–746CrossRefPubMed
22.
Zurück zum Zitat Roffi M, Patrono C, Collet JP, Mueller C, Valgimigli M, Andreotti F et al (2016) 2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: Task Force for the Management of Acute Coronary Syndromes in Patients Presenting without Persistent ST-Segment Elevation of the European Society of Cardiology (ESC). Eur Heart J 37(3):267–315CrossRefPubMed Roffi M, Patrono C, Collet JP, Mueller C, Valgimigli M, Andreotti F et al (2016) 2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: Task Force for the Management of Acute Coronary Syndromes in Patients Presenting without Persistent ST-Segment Elevation of the European Society of Cardiology (ESC). Eur Heart J 37(3):267–315CrossRefPubMed
23.
Zurück zum Zitat Thiele H, de Waha S, Zeymer U, Desch S, Scheller B, Lauer B et al (2014) Effect of aspiration thrombectomy on microvascular obstruction in NSTEMI patients: the TATORT-NSTEMI trial. J Am Coll Cardiol 64(11):1117–1124CrossRefPubMed Thiele H, de Waha S, Zeymer U, Desch S, Scheller B, Lauer B et al (2014) Effect of aspiration thrombectomy on microvascular obstruction in NSTEMI patients: the TATORT-NSTEMI trial. J Am Coll Cardiol 64(11):1117–1124CrossRefPubMed
24.
Zurück zum Zitat Meyer-Saraei R, de Waha S, Eitel I, Desch S, Scheller B, Bohm M et al (2017) Thrombus aspiration in non-ST-elevation myocardial infarction – 12-month clinical outcome of the randomised TATORT-NSTEMI trial. Eur Heart J Acute Cardiovasc Care 6(1):10–17CrossRefPubMed Meyer-Saraei R, de Waha S, Eitel I, Desch S, Scheller B, Bohm M et al (2017) Thrombus aspiration in non-ST-elevation myocardial infarction – 12-month clinical outcome of the randomised TATORT-NSTEMI trial. Eur Heart J Acute Cardiovasc Care 6(1):10–17CrossRefPubMed
25.
Zurück zum Zitat Jolly SS, James S, Džavík V, Cairns JA, Mahmoud KD, Zijlstra F et al (2017) Thrombus aspiration in ST-segment–elevation myocardial infarction. An individual patient meta-analysis: thrombectomy trialists collaboration. Circulation 135(2):143–152CrossRefPubMed Jolly SS, James S, Džavík V, Cairns JA, Mahmoud KD, Zijlstra F et al (2017) Thrombus aspiration in ST-segment–elevation myocardial infarction. An individual patient meta-analysis: thrombectomy trialists collaboration. Circulation 135(2):143–152CrossRefPubMed
26.
Zurück zum Zitat Cassese S, Kufner S, Xhepa E, Byrne RA, Kreutzer J, Ibrahim T et al (2016) Three-year efficacy and safety of new- versus early-generation drug-eluting stents for unprotected left main coronary artery disease insights from the ISAR-LEFT MAIN and ISAR-LEFT MAIN 2 trials. Clin Res Cardiol 105(7):575–584CrossRefPubMed Cassese S, Kufner S, Xhepa E, Byrne RA, Kreutzer J, Ibrahim T et al (2016) Three-year efficacy and safety of new- versus early-generation drug-eluting stents for unprotected left main coronary artery disease insights from the ISAR-LEFT MAIN and ISAR-LEFT MAIN 2 trials. Clin Res Cardiol 105(7):575–584CrossRefPubMed
27.
Zurück zum Zitat Zeymer U, Suryapranata H, Monassier JP, Opolski G, Davies J, Rasmanis G et al (2001) The Na+/H + exchange inhibitor eniporide as an adjunct to early reperfusion therapy for acute myocardial infarction. Results of the evaluation of the safety and cardioprotective effects of eniporide in acute myocardial infarction (ESCAMI) trial. J Am Coll Cardiol 38:1644–1650CrossRefPubMed Zeymer U, Suryapranata H, Monassier JP, Opolski G, Davies J, Rasmanis G et al (2001) The Na+/H + exchange inhibitor eniporide as an adjunct to early reperfusion therapy for acute myocardial infarction. Results of the evaluation of the safety and cardioprotective effects of eniporide in acute myocardial infarction (ESCAMI) trial. J Am Coll Cardiol 38:1644–1650CrossRefPubMed
28.
Zurück zum Zitat Eitel I, Stiermaier T, Rommel KP, Fuernau G, Sandri M, Mangner N et al (2015) Cardioprotection by combined intrahospital remote ischaemic perconditioning and postconditioning in ST-elevation myocardial infarction: the randomized LIPSIA CONDITIONING trial. Eur Heart J 36(44):3049–3057CrossRefPubMed Eitel I, Stiermaier T, Rommel KP, Fuernau G, Sandri M, Mangner N et al (2015) Cardioprotection by combined intrahospital remote ischaemic perconditioning and postconditioning in ST-elevation myocardial infarction: the randomized LIPSIA CONDITIONING trial. Eur Heart J 36(44):3049–3057CrossRefPubMed
29.
Zurück zum Zitat Katus H, Ziegler A, Ekinci O, Giannitsis E, Stough WG, Achenbach S et al (2017) Early diagnosis of acute coronary syndrome. Eur Heart J 38(41):3049–3055CrossRefPubMed Katus H, Ziegler A, Ekinci O, Giannitsis E, Stough WG, Achenbach S et al (2017) Early diagnosis of acute coronary syndrome. Eur Heart J 38(41):3049–3055CrossRefPubMed
30.
Zurück zum Zitat Hamm CW, Goldmann BU, Heeschen C, Kreymann G, Berger J, Meinertz T (1997) Emergency room triage of patients with acute chest pain by means of rapid testing for cardiac troponin T or troponin I. N Engl J Med 337(23):1648–1653CrossRefPubMed Hamm CW, Goldmann BU, Heeschen C, Kreymann G, Berger J, Meinertz T (1997) Emergency room triage of patients with acute chest pain by means of rapid testing for cardiac troponin T or troponin I. N Engl J Med 337(23):1648–1653CrossRefPubMed
31.
Zurück zum Zitat Hamm CW, Heeschen C, Goldmann B, Vahanian A, Adgey J, Miguel CM et al (1999) Benefit of abciximab in patients with refractory unstable angina in relation to serum troponin T levels. c7E3 Fab antiplatelet therapy in unstable refractory angina (CAPTURE) Study Investigators. N Engl J Med 340(21):1623–1629CrossRefPubMed Hamm CW, Heeschen C, Goldmann B, Vahanian A, Adgey J, Miguel CM et al (1999) Benefit of abciximab in patients with refractory unstable angina in relation to serum troponin T levels. c7E3 Fab antiplatelet therapy in unstable refractory angina (CAPTURE) Study Investigators. N Engl J Med 340(21):1623–1629CrossRefPubMed
32.
Zurück zum Zitat Keller T, Zeller T, Ojeda F, Tzikas S, Lillpopp L, Sinning C et al (2011) Serial changes in highly sensitive troponin I assay and early diagnosis of myocardial infarction. JAMA 306(24):2684–2693CrossRefPubMed Keller T, Zeller T, Ojeda F, Tzikas S, Lillpopp L, Sinning C et al (2011) Serial changes in highly sensitive troponin I assay and early diagnosis of myocardial infarction. JAMA 306(24):2684–2693CrossRefPubMed
33.
Zurück zum Zitat Keller T, Zeller T, Peetz D, Tzikas S, Roth A, Czyz E et al (2009) Sensitive troponin I assay in early diagnosis of acute myocardial infarction. N Engl J Med 361(9):868–877CrossRefPubMed Keller T, Zeller T, Peetz D, Tzikas S, Roth A, Czyz E et al (2009) Sensitive troponin I assay in early diagnosis of acute myocardial infarction. N Engl J Med 361(9):868–877CrossRefPubMed
34.
Zurück zum Zitat Schroder K, Wegscheider K, Zeymer U, Tebbe U, Schroder R (2001) Extent of ST-segment deviation in a single electrocardiogram lead 90 min after thrombolysis as a predictor of medium-term mortality in acute myocardial infarction. Lancet 358(9292):1479–1486CrossRefPubMed Schroder K, Wegscheider K, Zeymer U, Tebbe U, Schroder R (2001) Extent of ST-segment deviation in a single electrocardiogram lead 90 min after thrombolysis as a predictor of medium-term mortality in acute myocardial infarction. Lancet 358(9292):1479–1486CrossRefPubMed
35.
Zurück zum Zitat Schroder R (2004) Prognostic impact of early ST-segment resolution in acute ST-elevation myocardial infarction. Circulation 110(21):e506-10CrossRefPubMed Schroder R (2004) Prognostic impact of early ST-segment resolution in acute ST-elevation myocardial infarction. Circulation 110(21):e506-10CrossRefPubMed
36.
Zurück zum Zitat Eitel I, de Waha S, Wohrle J, Fuernau G, Lurz P, Pauschinger M et al (2014) Comprehensive prognosis assessment by CMR imaging after ST-segment elevation myocardial infarction. J Am Coll Cardiol 64(12):1217–1226CrossRefPubMed Eitel I, de Waha S, Wohrle J, Fuernau G, Lurz P, Pauschinger M et al (2014) Comprehensive prognosis assessment by CMR imaging after ST-segment elevation myocardial infarction. J Am Coll Cardiol 64(12):1217–1226CrossRefPubMed
37.
Zurück zum Zitat de Waha S, Desch S, Eitel I, Fuernau G, Zachrau J, Leuschner A et al (2010) Impact of early vs. late microvascular obstruction assessed by magnetic resonance imaging on long-term outcome after ST-elevation myocardial infarction: a comparison with traditional prognostic markers. Eur Heart J 31:2660–2668CrossRefPubMed de Waha S, Desch S, Eitel I, Fuernau G, Zachrau J, Leuschner A et al (2010) Impact of early vs. late microvascular obstruction assessed by magnetic resonance imaging on long-term outcome after ST-elevation myocardial infarction: a comparison with traditional prognostic markers. Eur Heart J 31:2660–2668CrossRefPubMed
38.
Zurück zum Zitat de Waha S, Patel MR, Granger CB, Ohman EM, Maehara A, Eitel I et al (2017) Relationship between microvascular obstruction and adverse events following primary PCI for STEMI: An individual patient data pooled analysis from 7 randomised trials. Eur Heart J 38:3502–3510CrossRefPubMed de Waha S, Patel MR, Granger CB, Ohman EM, Maehara A, Eitel I et al (2017) Relationship between microvascular obstruction and adverse events following primary PCI for STEMI: An individual patient data pooled analysis from 7 randomised trials. Eur Heart J 38:3502–3510CrossRefPubMed
39.
Zurück zum Zitat Hochman JS, Sleeper LA, Webb JG, Sanborn TA, White HD, Talley JD et al (1999) Early revascularization in acute myocardial infarction complicated by cardiogenic shock. SHOCK Investigators. Should we emergently revascularize occluded coronaries for cardiogenic shock. N Engl J Med 341(9):625 – 34CrossRefPubMed Hochman JS, Sleeper LA, Webb JG, Sanborn TA, White HD, Talley JD et al (1999) Early revascularization in acute myocardial infarction complicated by cardiogenic shock. SHOCK Investigators. Should we emergently revascularize occluded coronaries for cardiogenic shock. N Engl J Med 341(9):625 – 34CrossRefPubMed
40.
Zurück zum Zitat Hochman JS, Sleeper LA, Webb JG, Dzavik V, Buller CE, Aylward P et al (2006) Early revascularization and long-term survival in cardiogenic shock complicating acute myocardial infarction. JAMA 295(21):2511–2515CrossRefPubMedPubMedCentral Hochman JS, Sleeper LA, Webb JG, Dzavik V, Buller CE, Aylward P et al (2006) Early revascularization and long-term survival in cardiogenic shock complicating acute myocardial infarction. JAMA 295(21):2511–2515CrossRefPubMedPubMedCentral
41.
Zurück zum Zitat Zeymer U, Vogt A, Zahn R, Weber MA, Tebbe U, Gottwik M et al (2004) Predictors of in-hospital mortality in 1333 patients with acute myocardial infarction complicated by cardiogenic shock treated with primary percutaneous coronary intervention (PCI); Results of the primary PCI registry of the Arbeitsgemeinschaft Leitende Kardiologische Krankenhausarzte (ALKK). Eur Heart J 25(4):322–328CrossRefPubMed Zeymer U, Vogt A, Zahn R, Weber MA, Tebbe U, Gottwik M et al (2004) Predictors of in-hospital mortality in 1333 patients with acute myocardial infarction complicated by cardiogenic shock treated with primary percutaneous coronary intervention (PCI); Results of the primary PCI registry of the Arbeitsgemeinschaft Leitende Kardiologische Krankenhausarzte (ALKK). Eur Heart J 25(4):322–328CrossRefPubMed
42.
Zurück zum Zitat Scholz KH, Maier SKG, Maier LS, Lengenfelder B, Jacobshagen C, Jung J et al (2018) Impact of treatment delay on mortality in ST-segment elevation myocardial infarction (STEMI) patients presenting with and without haemodynamic instability: results from the German prospective, multicentre FITT-STEMI trial. Eur Heart J 39(13):1065–1074CrossRefPubMedPubMedCentral Scholz KH, Maier SKG, Maier LS, Lengenfelder B, Jacobshagen C, Jung J et al (2018) Impact of treatment delay on mortality in ST-segment elevation myocardial infarction (STEMI) patients presenting with and without haemodynamic instability: results from the German prospective, multicentre FITT-STEMI trial. Eur Heart J 39(13):1065–1074CrossRefPubMedPubMedCentral
43.
Zurück zum Zitat Stegman BM, Newby LK, Hochman JS, Ohman EM (2012) Post-myocardial infarction cardiogenic shock is a systemic illness in need of systemic treatment: Is therapeutic hypothermia one possibility? J Am Coll Cardiol 59(7):644–647CrossRefPubMed Stegman BM, Newby LK, Hochman JS, Ohman EM (2012) Post-myocardial infarction cardiogenic shock is a systemic illness in need of systemic treatment: Is therapeutic hypothermia one possibility? J Am Coll Cardiol 59(7):644–647CrossRefPubMed
44.
Zurück zum Zitat Fuernau G, Beck J, Desch S, Eitel I, Erbs S, Mangner N et al. Mild hypothermia in cardiogenic shock complicating myocardial infarction—the randomized SHOCK-COOL pilot trial. Eur Heart J. 2016;Abstract Supplement:P5199 Fuernau G, Beck J, Desch S, Eitel I, Erbs S, Mangner N et al. Mild hypothermia in cardiogenic shock complicating myocardial infarction—the randomized SHOCK-COOL pilot trial. Eur Heart J. 2016;Abstract Supplement:P5199
45.
Zurück zum Zitat Shah M, Patnaik S, Patel B, Ram P, Garg L, Agarwal M et al (2018) Trends in mechanical circulatory support use and hospital mortality among patients with acute myocardial infarction and non-infarction related cardiogenic shock in the United States. Clin Res Cardiol 107(4):287–303CrossRefPubMed Shah M, Patnaik S, Patel B, Ram P, Garg L, Agarwal M et al (2018) Trends in mechanical circulatory support use and hospital mortality among patients with acute myocardial infarction and non-infarction related cardiogenic shock in the United States. Clin Res Cardiol 107(4):287–303CrossRefPubMed
46.
Zurück zum Zitat Thiele H, Zeymer U, Neumann FJ, Ferenc M, Olbrich HG, Hausleiter J et al (2013) Intra-aortic balloon counterpulsation in acute myocardial infarction complicated by cardiogenic shock (IABP-SHOCK II): final 12 month results of a randomised, open-label trial. Lancet 382(9905):1638–1645CrossRefPubMed Thiele H, Zeymer U, Neumann FJ, Ferenc M, Olbrich HG, Hausleiter J et al (2013) Intra-aortic balloon counterpulsation in acute myocardial infarction complicated by cardiogenic shock (IABP-SHOCK II): final 12 month results of a randomised, open-label trial. Lancet 382(9905):1638–1645CrossRefPubMed
47.
Zurück zum Zitat de Waha S, Graf T, Desch S, Fuernau G, Eitel I, Pöss J et al (2017) Outcome of elderly undergoing extracorporeal life support in refractory cardiogenic shock. Clin Res Cardiol 106(5):379–385CrossRefPubMed de Waha S, Graf T, Desch S, Fuernau G, Eitel I, Pöss J et al (2017) Outcome of elderly undergoing extracorporeal life support in refractory cardiogenic shock. Clin Res Cardiol 106(5):379–385CrossRefPubMed
48.
Zurück zum Zitat Ouweneel DM, Schotborgh JV, Limpens J, Sjauw KD, Engstrom AE, Lagrand WK et al (2016) Extracorporeal life support during cardiac arrest and cardiogenic shock: a systematic review and meta-analysis. Intensive Care Med 42(12):1922–1934CrossRefPubMedPubMedCentral Ouweneel DM, Schotborgh JV, Limpens J, Sjauw KD, Engstrom AE, Lagrand WK et al (2016) Extracorporeal life support during cardiac arrest and cardiogenic shock: a systematic review and meta-analysis. Intensive Care Med 42(12):1922–1934CrossRefPubMedPubMedCentral
49.
Zurück zum Zitat Thiele H, Jobs A, Ouweneel DM, Henriques JPS, Seyfarth M, Desch S et al (2017) Percutaneous short-term active mechanical support devices in cardiogenic shock: a systematic review and collaborative meta-analysis of randomized trials. Eur Heart J 38:3523–3531CrossRefPubMed Thiele H, Jobs A, Ouweneel DM, Henriques JPS, Seyfarth M, Desch S et al (2017) Percutaneous short-term active mechanical support devices in cardiogenic shock: a systematic review and collaborative meta-analysis of randomized trials. Eur Heart J 38:3523–3531CrossRefPubMed
Metadaten
Titel
German contribution to development and innovations in the management of acute myocardial infarction and cardiogenic shock
verfasst von
Hans-Josef Feistritzer
Steffen Desch
Suzanne de Waha
Alexander Jobs
Uwe Zeymer
Holger Thiele
Publikationsdatum
16.05.2018
Verlag
Springer Berlin Heidelberg
Erschienen in
Clinical Research in Cardiology / Ausgabe Sonderheft 2/2018
Print ISSN: 1861-0684
Elektronische ISSN: 1861-0692
DOI
https://doi.org/10.1007/s00392-018-1276-5

Weitere Artikel der Sonderheft 2/2018

Clinical Research in Cardiology 2/2018 Zur Ausgabe

Update Kardiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.