Skip to main content
Erschienen in: Archives of Gynecology and Obstetrics 2/2019

05.12.2018 | Maternal-Fetal Medicine

Gestational age and the long-term impact on children’s infectious urinary morbidity

verfasst von: Elisheva Padeh, Tamar Wainstock, Eyal Sheiner, Daniella Landau, Asnat Walfisch

Erschienen in: Archives of Gynecology and Obstetrics | Ausgabe 2/2019

Einloggen, um Zugang zu erhalten

Abstract

Purpose

Given the negative impact of prematurity on offspring’s health, we sought to determine whether different gestational ages at birth impact differently on the prevalence of childhood infectious urinary morbidity in the offspring.

Methods

In this population-based cohort analysis, all singleton deliveries occurring between 1991 and 2014 at a single regional tertiary medical center were included. Gestational age upon delivery was sub-divided into early preterm (< 34 weeks), late preterm (34–36 6/7 weeks), early term (37–38 6/7 weeks), full term (39–40 6/7 weeks), late term (41–41 6/7 weeks) and post-term (> 42 weeks). Congenital malformations were excluded. Rates of infectious urinary morbidity-related hospitalizations of offspring up to age 18 years were assessed using a survival curve and a Cox multivariable model.

Results

During the study period, 238,620 deliveries met the inclusion criteria. Urinary-related hospitalization (n = 1395) rates decreased as gestational age increased, from 1.7% in the early preterm group, 0.9% in the late preterm group, 0.6% in the early-term group and only 0.5% in the full, late and post-term groups (p > 0.001; chi-square test for trends). In the Cox model, controlled for maternal age, preterm as well as early-term deliveries exhibited an independent association with pediatric urinary morbidity as compared with full term (early preterm: aHR—3.305, 95% CI 2.4–4.54; late preterm: aHR—1.63, 95% CI 1.33–1.99; early term: aHR—1.26, 95% CI 1.1–1.43, p = 0.01).

Conclusions

Deliveries occurring at preterm and at early term are independently associated with pediatric urinary morbidity in the offspring. This risk decreases as gestational age advances.
Anhänge
Nur mit Berechtigung zugänglich
Literatur
23.
Zurück zum Zitat Blencowe H, Cousens S, Oestergaard MZ, Chou D, Moller A-B, Narwal R, Adler A, Vera Garcia C, Rohde S, Say L, Lawn JE (2012) National, regional, and worldwide estimates of preterm birth rates in the year 2010 with time trends since 1990 for selected countries: a systematic analysis and implications. Lancet 379(9832):2162–2172. https://doi.org/10.1016/S0140-6736(12)60820-4 CrossRef Blencowe H, Cousens S, Oestergaard MZ, Chou D, Moller A-B, Narwal R, Adler A, Vera Garcia C, Rohde S, Say L, Lawn JE (2012) National, regional, and worldwide estimates of preterm birth rates in the year 2010 with time trends since 1990 for selected countries: a systematic analysis and implications. Lancet 379(9832):2162–2172. https://​doi.​org/​10.​1016/​S0140-6736(12)60820-4 CrossRef
Metadaten
Titel
Gestational age and the long-term impact on children’s infectious urinary morbidity
verfasst von
Elisheva Padeh
Tamar Wainstock
Eyal Sheiner
Daniella Landau
Asnat Walfisch
Publikationsdatum
05.12.2018
Verlag
Springer Berlin Heidelberg
Erschienen in
Archives of Gynecology and Obstetrics / Ausgabe 2/2019
Print ISSN: 0932-0067
Elektronische ISSN: 1432-0711
DOI
https://doi.org/10.1007/s00404-018-4973-4

Weitere Artikel der Ausgabe 2/2019

Archives of Gynecology and Obstetrics 2/2019 Zur Ausgabe

Update Gynäkologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert – ganz bequem per eMail.