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Erschienen in: Intensive Care Medicine 9/2017

19.04.2017 | Letter

Glycemic control, mortality, secondary infection, and hypoglycemia in critically ill pediatric patients: a systematic review and network meta-analysis of randomized controlled trials

verfasst von: Tomohide Yamada, Nobuhiro Shojima, Kazuo Hara, Hisashi Noma, Toshimasa Yamauchi, Takashi Kadowaki

Erschienen in: Intensive Care Medicine | Ausgabe 9/2017

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Excerpt

We recently reported a network meta-analysis on the risk of mortality or hypoglycemia associated with different glycemic control targets in critically ill adults [1, 2]. Our analysis of 36 randomized trials (17,996 patients) showed no reduction of mortality by tight glycemic control (blood glucose: 4.4–<6.1 mmol/l), while hypoglycemia was fivefold more frequent versus mild control (7.8–<10.0 mmol/l) or very mild control (10.0–<12.2 mmol/l) [1]. …
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Literatur
1.
Zurück zum Zitat Yamada T, Shojima N, Noma H et al (2017) Glycemic control, mortality, and hypoglycemia in critically ill patients: a systematic review and network meta-analysis of randomized controlled trials. Intensive Care Med 43(1):1–15CrossRefPubMed Yamada T, Shojima N, Noma H et al (2017) Glycemic control, mortality, and hypoglycemia in critically ill patients: a systematic review and network meta-analysis of randomized controlled trials. Intensive Care Med 43(1):1–15CrossRefPubMed
2.
Zurück zum Zitat Yamada T (2017) Achieved glucose level and mortality risk in randomized clinical trials. Resuscitation 110:e3–e4CrossRefPubMed Yamada T (2017) Achieved glucose level and mortality risk in randomized clinical trials. Resuscitation 110:e3–e4CrossRefPubMed
3.
Zurück zum Zitat Agus MS, Wypij D, Hirshberg EL, et al (2017) HALF-PINT Study Investigators and the PALISI Network. Tight Glycemic Control in Critically Ill Children. N Engl J Med. doi:10.1056/NEJMoa1612348 (Epub ahead of print) PubMed PMID: 28118549 Agus MS, Wypij D, Hirshberg EL, et al (2017) HALF-PINT Study Investigators and the PALISI Network. Tight Glycemic Control in Critically Ill Children. N Engl J Med. doi:10.​1056/​NEJMoa1612348 (Epub ahead of print) PubMed PMID: 28118549
4.
Zurück zum Zitat Mesotten D, Gielen M, Sterken C, et al (2012) Neurocognitive development of children 4 years after critical illness and treatment with tight glucose control: a randomized controlled trial. JAMA. 308(16):1641–50. PubMed PMID: 23101118 Mesotten D, Gielen M, Sterken C, et al (2012) Neurocognitive development of children 4 years after critical illness and treatment with tight glucose control: a randomized controlled trial. JAMA. 308(16):1641–50. PubMed PMID: 23101118
5.
Zurück zum Zitat Rhodes A, Evans LE, Alhazzani W, et al (2017) Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016. Intensive Care Med. doi:10.1007/s00134-017-4683-6. (Epub ahead of print) PubMed PMID: 28101605 Rhodes A, Evans LE, Alhazzani W, et al (2017) Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016. Intensive Care Med. doi:10.​1007/​s00134-017-4683-6. (Epub ahead of print) PubMed PMID: 28101605
Metadaten
Titel
Glycemic control, mortality, secondary infection, and hypoglycemia in critically ill pediatric patients: a systematic review and network meta-analysis of randomized controlled trials
verfasst von
Tomohide Yamada
Nobuhiro Shojima
Kazuo Hara
Hisashi Noma
Toshimasa Yamauchi
Takashi Kadowaki
Publikationsdatum
19.04.2017
Verlag
Springer Berlin Heidelberg
Erschienen in
Intensive Care Medicine / Ausgabe 9/2017
Print ISSN: 0342-4642
Elektronische ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-017-4801-5

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