Erschienen in:
19.04.2017 | Letter
Glycemic control, mortality, secondary infection, and hypoglycemia in critically ill pediatric patients: a systematic review and network meta-analysis of randomized controlled trials
verfasst von:
Tomohide Yamada, Nobuhiro Shojima, Kazuo Hara, Hisashi Noma, Toshimasa Yamauchi, Takashi Kadowaki
Erschienen in:
Intensive Care Medicine
|
Ausgabe 9/2017
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Excerpt
We recently reported a network meta-analysis on the risk of mortality or hypoglycemia associated with different glycemic control targets in critically ill adults [
1,
2]. Our analysis of 36 randomized trials (17,996 patients) showed no reduction of mortality by tight glycemic control (blood glucose: 4.4–<6.1 mmol/l), while hypoglycemia was fivefold more frequent versus mild control (7.8–<10.0 mmol/l) or very mild control (10.0–<12.2 mmol/l) [
1]. …