08.09.2016 | Original Article
Granulocyte transfusions in critically ill children with prolonged neutropenia: side effects and survival rates from a single-center analysis
Erschienen in: European Journal of Pediatrics | Ausgabe 10/2016
Einloggen, um Zugang zu erhaltenAbstract
What is known:
• Granulocyte transfusions for neutropenic patients have been used for over 40 years
• The effectiveness of the technique remains controversial
• Patient and donor safety remain debated
• New mobilization protocols generate higher yields of granulocytes
|
What is new:
• Granulocyte collection can safely be performed
• Granulocytes can safely be administered to patients
• Lower patient weight and age-/sex-adjusted weight are associated with better survival rates
• Patients receiving above 0.13 × 10
10
cells per kg body weight had an excellent outcome
• Further standardized, prospective studies are warranted
|