09.08.2016 | Original Article
Growth, metabolic markers, and cognition in 8-year old children born prematurely, follow-up of a randomized controlled trial with essential fatty acids
Erschienen in: European Journal of Pediatrics | Ausgabe 9/2016
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What is Known:
• Preterm children have increased risk of lower intelligence quotient (IQ), reduced growth, and abnormal metabolic status.
• Early intake of docosahexaenoic acid (DHA) and arachidonic acid (AA), as well as early growth pattern, may influence both IQ and metabolic status.
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What is New:
• Early intervention with DHA and AA led to reduced insulin-like growth factor-1 in blood at 8 years of age.
• Weight gain during first year of life was neither associated with impaired metabolic markers nor improved IQ at follow-up.
• Current DHA status was a significant predictor of higher IQ at 8 years, also when maternal education and birth weight were included in the model.
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